Recent progress in genetic manipulations and calorie-restricted diets in laboratory animals hold forth the promise that someday science will enable us to exert total control over our own biological aging.Nearly all scientists who study the biology of aging agree that we will someday be able to substantially slow down the aging process, extending our productive, youthful lives. Dr. Aubrey de Grey is perhaps the most bullish of all such researchers. As has been reported in media outlets ranging from 60 Minutes to The New York Times, Dr. de Grey believes that the key biomedical technology required to eliminate aging-derived debilitation and death entirely--technology that would not only slow but periodically reverse age-related physiological decay, leaving us biologically young into an indefinite future--is now within reach.In Ending Aging, Dr. de Grey and his research assistant Michael Rae describe the details of this biotechnology. They explain that the aging of the human body, just like the aging of man-made machines, results from an accumulation of various types of damage.  As with man-made machines, this damage can periodically be repaired, leading to indefinite extension of the machine's fully functional lifetime, just as is routinely done with classic cars.  We already know what types of damage accumulate in the human body, and we are moving rapidly toward the comprehensive development of technologies to remove that damage.  By demystifying aging and its postponement for the nonspecialist reader, de Grey and Rae systematically dismantle the fatalist presumption that aging will forever defeat the efforts of medical science.

    An evolutionary perspective forms the foundation of the entire discussion. The book begins with the natural history of the planet, considers portions of the whole in the middle chapters, and ends with another perspective of the entire planet in the concluding chapter. Its unique organization of focusing only on several key concepts in each chapter sets it apart from the competition. .

    Looking at the organisms that have made all this possible gives us a new way of understanding how we got here--and perhaps of thinking about where we're going. Instead of a history of which great scientists had which great ideas, this story of passionflowers and hawkweeds, of zebra fish and viruses, offers a bird's (or rodent's) eye view of the work that makes science possible.Mixing the celebrities of genetics, like the fruit fly, with forgotten players such as the evening primrose, the book follows the unfolding history of biological inheritance from Aristotle's search for the "universal, absolute truth of fishiness" to the apparently absurd speculations of eighteenth-century natural philosophers to the spectacular findings of our day--which may prove to be the absurdities of tomorrow.The result is a quirky, enlightening, and thoroughly engaging perspective on the history of heredity and genetics, tracing the slow, uncertain path--complete with entertaining diversions and dead ends--that led us from the ancient world's understanding of inheritance to modern genetics.

    This book surveys the most important computer algorithms currently in use and provides a full treatment of data structures and algorithms for sorting, searching, graph processing, and string processing -- including fifty algorithms every programmer should know. In this edition, new Java implementations are written in an accessible modular programming style, where all of the code is exposed to the reader and ready to use.The algorithms in this book represent a body of knowledge developed over the last 50 years that has become indispensable, not just for professional programmers and computer science students but for any student with interests in science, mathematics, and engineering, not to mention students who use computation in the liberal arts.The companion web site, algs4.cs.princeton.edu contains An online synopsis Full Java implementations Test data Exercises and answers Dynamic visualizations Lecture slides Programming assignments with checklists Links to related material The MOOC related to this book is accessible via the "Online Course" link at algs4.cs.princeton.edu. The course offers more than 100 video lecture segments that are integrated with the text, extensive online assessments, and the large-scale discussion forums that have proven so valuable. Offered each fall and spring, this course regularly attracts tens of thousands of registrants.Robert Sedgewick and Kevin Wayne are developing a modern approach to disseminating knowledge that fully embraces technology, enabling people all around the world to discover new ways of learning and teaching. By integrating their textbook, online content, and MOOC, all at the state of the art, they have built a unique resource that greatly expands the breadth and depth of the educational experience.

    Using the recommended APA undergraduate psychology learning outcomes, the authors establish clear learning objectives for students and tie the text assessment to these objectives.

    Hemostasis and coagulation theory, testing, and instrumentation are also thoroughly discussed. Beautiful full-color illustrations throughout the text enhance comprehension and allow students to realistically visualize hematology concepts.Detailed, full-color illustrations appear near hematology concept discussions to visually support comprehension and recognition.Opening Case Studies present real-life scenarios to apply concepts presented in each chapter.Learning Objectives and Review Questions work together to list expected outcomes and then test those concepts for each chapter.A Bulleted Summary highlights the key concepts at the end of each chapter.Hematology/Hemostasis Reference Ranges inside the front and back covers provide quick reference.Three new chapters detail significant information: An Overview of Clinical Laboratory Hematology, Hematology in Selected Populations, and Monitoring Anticoagulant Therapy.All chapters have been revised to feature the most current technology and research updates.The included Glossary of Terms and consistent pedagogy ensure a cohesive, effective tool for learning.Two well-respected editors contributed more significantly to this third edition: George Fritsma shared his expertise for the Hemostasis section and Kathy Doig managed the pedagogical features.

    Did you know that two of every three people reading this book will die for reasons connected with the genes they carry? That our DNA gradually changes with age, which is why older parents are more likely to give birth to children with genetic defects than younger parents? That each individual is a kind of living fossil, carrying within a genetic record that goes back to the beginnings of humanity? In The Language of Genes, renowned geneticist Steve Jones explores the meanings and explodes the myths of human genetics, offering up an extraordinary picture of what we are, what we were, and what we may become."An essential book for anyone interested in the development and possible future of our species."--Kirkus Reviews"This is one of the most insightful books on genetics to date and certainly the most entertaining."--The Wall Street Journal

    This book includes a companion CD-ROM that adds a visual emphasis with animations.

    Its job is to protect us from cancer. This gene--known simply as p53--constantly scans our cells to ensure that when they grow and divide as part of the routine maintenance of our bodies, they do so without mishap. If a cell makes a mistake in copying its DNA during the process of division, p53 stops it in its tracks, sending in the repair team before allowing the cell to carry on dividing. If the mistake is irreparable and the rogue cell threatens to grow out of control (as happens in cancer), p53 commands the cell to commit suicide. Cancer cannot develop unless p53 itself is damaged or handicapped by some other fault in the system. Not surprisingly, p53 is the most studied single gene in history. p53: The Gene that Cracked the Cancer Code tells the story of the discovery of the gene and of medical science's mission to unravel its mysteries and get to the heart of what happens in our cells when they turn cancerous. Through the personal accounts of key researchers, the book reveals the excitement of the hunt for new cures--the hype, the enthusiasm, the lost opportunities, the blind alleys and the thrilling breakthroughs. As the long-anticipated revolution in cancer treatment tailored to each individual patient's symptoms starts to take off at last, p53 is at the cutting edge. This is a timely tale of scientific discovery and advances in our understanding of a disease that still affects more than one in three of us at some point in our lives.

    The 10,000 Year Explosion: How Civilization Accelerated Human Evolution

    Its colorful design and conversational writing style make it appealing and accessible to students and has made it the leading Nutrition text for the non-majors or mixed majors/non-majors introductory course.

    Its step-by-step approach guides you through the process, helping you formulate a nursing diagnosis based on known information and assessment findings; identify the appropriate nursing diagnosis; and create a care plan that includes desired outcomes, interventions, and evidence-based rationales. Nursing Diagnosis Handbook is an essential care planning resource you will turn to again and again throughout your nursing education and career.Provides care plans for every NANDA-I approved nursing diagnosis.Includes examples of and suggested NIC and NOC interventions and outcomes for each care plan.A convenient A-to-Z organization in Sections I and II helps you quickly locate key information.Evidence-based practice information is incorporated throughout.Includes complete coverage of pediatric, geriatric, and multicultural considerations, as well as home care and client/family teaching guidelines for each condition.A Care Plan Constructor on the Evolve website helps you create customized plans of care.Features the most up-to-date 2007-2008 NANDA-I approved nursing diagnoses, including approximately 15 new, 20 revised, and 5 replacement diagnoses.Provides a more detailed explanation of NIC and NOC taxonomies and their use in care planning.Explanations of assessment versus action interventions help guide you to the correct choice of intervention.Covers important information on concept mapping.Patient/Family Teaching sections offer expanded wellness and health promotion information.Clustered wellness nursing diagnoses are quick and easy to locate.Includes the latest evidence-based nursing rationales.

    With the addition of new chapters, thorough updating, and a new co-author, this latest edition represents the definitive introduction to behavioral genetics: the crossroads where the fields of psychology, psychiatry, and genetics intersect.

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    It develops an understanding of function and evolution into the discussion of anatomy of the various systems.