Combining historical, social, and economic analysis with personal experiences of love and loss, Jacoby turns a caustic eye not only on the modern fiction that old age can be "defied" but also on the sentimental image of a past in which Americans supposedly revered their elders."Never Say Die" unmasks the fallacies promoted by twenty-first-century hucksters of longevity -- including health gurus claiming that boomers can stay "forever young" if they only live right, self-promoting biomedical businessmen predicting that ninety may soon become the new fifty and that a "cure" for the "disease" of aging is just around the corner, and wishful thinkers asserting that older means wiser. The author offers powerful evidence that America has always been a "youth culture" and that the plight of the neglected old dates from the early years of the republic. Today, as the oldest boomers turn sixty-five, it is imperative for them to distinguish between marketing hype and realistic hope about what lies ahead for the more than 70 million Americans who will be beyond the traditional retirement age by 2030. This wide-ranging reappraisal examines the explosion of Alzheimer's cases, the uncertain economic future of aging boomers, the predicament of women who make up an overwhelming majority of the oldest -- and poorest -- old, and the illusion that we can control the way we age and die.Jacoby raises the fundamental question of whether living longer is a good thing unless it means living better. Her book speaks to Americans, whatever their age, who draw courage and hope from facing reality instead of embracing that oldest of delusions, the fountain of youth.

    And there is no more accomplished and accessible guide than renowned neuroscientist David Eagleman to help us understand the nature and changing texture of that fabric. With his hallmark clarity and enthusiasm he reveals the myriad ways that the brain absorbs experience: developing, redeploying, organizing, and arranging the data it receives from the body's own absorption of external stimuli, which enables us to gain the skills, the facilities, and the practices that make us who we are. Eagleman covers decades of the most important research into the functioning of the brain and presents new discoveries from his own research as well: about the nature of synesthesia, about dreaming, and about wearable devices that are revolutionizing how we think about the five human senses. Finally, Livewired is as deeply informative as it is accessible and brilliantly engaging.

    Many studies have supported this, proving that life expectancy is 75 to 90 percent due to habits and only 10 to 25 percent due to genetics. This means that someone who is genetically destined to die at age 100 may not live past age 60 because of poor habits and lifestyle choices that cause accelerated aging and premature death. Conversely, a person can live to 100 and be functionally healthy. In this highly anticipated follow-up, Diana Schwarzbein, M.D., goes beyond the diet she introduced in her first book—which literally helped thousands of people lose weight—and offers a personalized anti-aging program for readers to heal their metabolisms and stop advanced aging in its tracks. Weaving in groundbreaking research and provocative case studies—including her own regeneration and that of her clients—she leads readers through a series of eye-opening questionnaires, which identify where they are on their path to either accelerated or healthy aging. Based on readers’ answers, she leads them to the “how-to” sections, which explain, in easy-to-follow and personalized detail, the steps they need to take to restore healthy functioning. For each unique situation, she covers five areas: Nutrition , Hormone Replacement Therapy (if needed), Tapering Off Toxic Chemicals or Avoiding Them Completely , Cross-Training Exercises and Stress Management. The Schwarzbein Principle II is sure to follow the success of the first book and will help people live a more healthful lifestyle by embracing a regeneration process to prevent and reverse accelerated aging.

    In 2017, it claimed nearly fifty thousand lives -- more than gunshots and car crashes combined, and almost as many Americans as were killed in the entire Vietnam War. But even as the overdose crisis ravages our nation -- straining our prison system, dividing families, and defying virtually every legislative solution to treat it-- few understand how it came to be.Opium tells the extraordinary and at times harrowing tale of how we arrived at today's crisis, "mak[ing] timely and startling connections among painkillers, politics, finance, and society" (Laurence Bergreen). The story begins with the discovery of poppy artifacts in ancient Mesopotamia, and goes on to explore how Greek physicians and obscure chemists discovered opium's effects and refined its power, how colonial empires marketed it around the world, and eventually how international drug companies developed a range of powerful synthetic opioids that led to an epidemic of addiction. Throughout, Dr. John Halpern and David Blistein reveal the fascinating role that opium has played in building our modern world, from trade networks to medical protocols to drug enforcement policies. Most importantly, they disentangle how crucial misjudgments, patterns of greed, and racial stereotypes served to transform one of nature's most effective painkillers into a source of unspeakable pain-and how, using the insights of history, state-of-the-art science, and a compassionate approach to the illness of addiction, we can overcome today's overdose epidemic.This urgent and masterfully woven narrative tells an epic story of how one beautiful flower became the fascination of leaders, tycoons, and nations through the centuries and in their hands exposed the fragility of our civilization.

    The shift toward automation is about to create a tsunami of unemployment. Not in the distant future—now. One recent estimate predicts 45 million American workers will lose their jobs within the next twelve years—jobs that won't be replaced. In a future marked by restlessness and chronic unemployment, what will happen to American society? In The War on Normal People, Andrew Yang paints a dire portrait of the American economy. Rapidly advancing technologies like artificial intelligence, robotics and automation software are making millions of Americans' livelihoods irrelevant. The consequences of these trends are already being felt across our communities in the form of political unrest, drug use, and other social ills. The future looks dire-but is it unavoidable? In The War on Normal People, Yang imagines a different future—one in which having a job is distinct from the capacity to prosper and seek fulfillment. At this vision's core is Universal Basic Income, the concept of providing all citizens with a guaranteed income-and one that is rapidly gaining popularity among forward-thinking politicians and economists. Yang proposes that UBI is an essential step toward a new, more durable kind of economy, one he calls "human capitalism."

    Now it could be the key to healing millions with genetic diseases of every type—from Alzheimer's and Parkinson's to diabetes and sickle cell anemia.In 1974, Joey O'Donnell was born with strange symptoms. His insatiable appetite, incessant vomiting, and a relentless cough—which shook his tiny, fragile body and made it difficult to draw breath—confounded doctors and caused his parents agonizing, sleepless nights. After six sickly months, his salty skin provided the critical clue: he was one of thousands of Americans with cystic fibrosis, an inherited lung disorder that would most likely kill him before his first birthday.The gene and mutation responsible for CF were found in 1989—discoveries that promised to lead to a cure for kids like Joey. But treatments unexpectedly failed and CF was deemed incurable. It was only after the Cystic Fibrosis Foundation, a grassroots organization founded by parents, formed an unprecedented partnership with a fledgling biotech company that transformative leaps in drug development were harnessed to produce groundbreaking new treatments: pills that could fix the crippled protein at the root of this deadly disease.From science writer Bijal P. Trivedi, Breath from Salt chronicles the riveting saga of cystic fibrosis, from its ancient origins to its identification in the dank autopsy room of a hospital basement, and from the CF gene's celebrated status as one of the first human disease genes ever discovered to the groundbreaking targeted genetic therapies that now promise to cure it.Told from the perspectives of the patients, families, physicians, scientists, and philanthropists fighting on the front lines, Breath from Salt is a remarkable story of unlikely scientific and medical firsts, of setbacks and successes, and of people who refused to give up hope—and a fascinating peek into the future of genetics and medicine.

    This new edition includes an all-embracing and incisive afterword that examines the current state of health care and our relationship with life as it approaches its terminus. It also discusses how we can take control of our own final days and those of our loved ones.Shewin Nuland's masterful How We Die is even more relevant than when it was first published.

    That’s a mistake, Tim Harford says in The Data Detective. We shouldn’t be suspicious of statistics—we need to understand what they mean and how they can improve our lives: they are, at heart, human behavior seen through the prism of numbers and are often “the only way of grasping much of what is going on around us.” If we can toss aside our fears and learn to approach them clearly—understanding how our own preconceptions lead us astray—statistics can point to ways we can live better and work smarter.As “perhaps the best popular economics writer in the world” (New Statesman), Tim Harford is an expert at taking complicated ideas and untangling them for millions of readers. In The Data Detective, he uses new research in science and psychology to set out ten strategies for using statistics to erase our biases and replace them with new ideas that use virtues like patience, curiosity, and good sense to better understand ourselves and the world. As a result, The Data Detective is a big-idea book about statistics and human behavior that is fresh, unexpected, and insightful.

    The ketogenic diet kick-starts your body's metabolism so it burns fat, instead of sugar, as its primary fuel. But most ketogenic plans are meat- and dairy-heavy, creating a host of other problems, especially for those who prefer plants at the center of the plate. Dr. Will Cole comes to the rescue with Ketotarian, which has all the fat-burning benefits without the antibiotics and hormones that are packed into most keto diets.First developed for individuals suffering from seizures, keto diets have been shown to reduce inflammation and lower the risk of many chronic health problems including Alzheimer's and some cancers. Adding a plant-based twist, Ketotarian includes more than 75 recipes that are vegetarian, vegan, or pescatarian, offering a range of delicious and healthy choices for achieving weight loss, renewed health, robust energy, and better brain function.Packed with expert tips, tricks, and advice for going--and staying--Ketotarian, including managing macronutrients, balancing electrolytes, and finding your carb sweet spot, this best-of-both-worlds program is a game-changer for anyone who wants to tame inflammation and achieve peak physical and mental performance. Let the Ketotarian revolution begin!

    Dr. Jeremy Brown, currently Director of Emergency Care Research at the National Institutes of Health, expounds on the flu's deadly past to solve the mysteries that could protect us from the next outbreak. In Influenza, he talks with leading epidemiologists, policy makers, and the researcher who first sequenced the genetic building blocks of the original 1918 virus to offer both a comprehensive history and a roadmap for understanding what’s to come.Dr. Brown digs into the discovery and resurrection of the flu virus in the frozen victims of the 1918 epidemic, as well as the bizarre remedies that once treated the disease, such as whiskey and blood-letting. Influenza also breaks down the current dialogue surrounding the disease, explaining the controversy over vaccinations, antiviral drugs like Tamiflu, and the federal government’s role in preparing for pandemic outbreaks. Though 100 years of advancement in medical research and technology have passed since the 1918 disaster, Dr. Brown warns that many of the most vital questions about the flu virus continue to confound even the leading experts.Influenza is an enlightening and unnerving look at a shapeshifting deadly virus that has been around long before people—and warns us that it may be many more years before we are able to conquer it for good.

    It doesn't shy away from the full range of viewpoints or from the most controversial issues--from superintelligence to meaning, consciousness and the ultimate physical limits on life in the cosmos.

    What's more, its potential is nearly limitless--every hour the sun beams down more energy than the world uses in a year. But in Taming the Sun, energy expert Varun Sivaram warns that the world is not yet equipped to harness erratic sunshine to meet most of its energy needs. And if solar's current surge peters out, prospects for replacing fossil fuels and averting catastrophic climate change will dim.Innovation can brighten those prospects, Sivaram explains, drawing on firsthand experience and original research spanning science, business, and government. Financial innovation is already enticing deep-pocketed investors to fund solar projects around the world, from the sunniest deserts to the poorest villages. Technological innovation could replace today's solar panels with coatings as cheap as paint and employ artificial photosynthesis to store intermittent sunshine as convenient fuels. And systemic innovation could add flexibility to the world's power grids and other energy systems so they can dependably channel the sun's unreliable energy.Unleashing all this innovation will require visionary public policy: funding researchers developing next-generation solar technologies, refashioning energy systems and economic markets, and putting together a diverse clean energy portfolio. Although solar can't power the planet by itself, it can be the centerpiece of a global clean energy revolution.A Council on Foreign Relations Book

     Where are we? Who are we? Are our emotions, our beliefs, and our hopes and dreams ultimately meaningless out there in the void? Does human purpose and meaning fit into a scientific worldview?In short chapters filled with intriguing historical anecdotes, personal asides, and rigorous exposition, readers learn the difference between how the world works at the quantum level, the cosmic level, and the human level--and then how each connects to the other.  Carroll's presentation of the principles that have guided the scientific revolution from Darwin and Einstein to the origins of life, consciousness, and the universe is dazzlingly unique.Carroll shows how an avalanche of discoveries in the past few hundred years has changed our world and what really matters to us. Our lives are dwarfed like never before by the immensity of space and time, but they are redeemed by our capacity to comprehend it and give it meaning.The Big Picture is an unprecedented scientific worldview, a tour de force that will sit on shelves alongside the works of Stephen Hawking, Carl Sagan, Daniel Dennett, and E. O. Wilson for years to come.

    Sapolsky's storytelling concept is delightful but it also has a powerful intrinsic logic: he starts by looking at the factors that bear on a person's reaction in the precise moment a behavior occurs, and then hops back in time from there, in stages, ultimately ending up at the deep history of our species and its evolutionary legacy.And so the first category of explanation is the neurobiological one. A behavior occurs--whether an example of humans at our best, worst, or somewhere in between. What went on in a person's brain a second before the behavior happened? Then Sapolsky pulls out to a slightly larger field of vision, a little earlier in time: What sight, sound, or smell caused the nervous system to produce that behavior? And then, what hormones acted hours to days earlier to change how responsive that individual is to the stimuli that triggered the nervous system? By now he has increased our field of vision so that we are thinking about neurobiology and the sensory world of our environment and endocrinology in trying to explain what happened.Sapolsky keeps going: How was that behavior influenced by structural changes in the nervous system over the preceding months, by that person's adolescence, childhood, fetal life, and then back to his or her genetic makeup? Finally, he expands the view to encompass factors larger than one individual. How did culture shape that individual's group, what ecological factors millennia old formed that culture? And on and on, back to evolutionary factors millions of years old.The result is one of the most dazzling tours d'horizon of the science of human behavior ever attempted, a majestic synthesis that harvests cutting-edge research across a range of disciplines to provide a subtle and nuanced perspective on why we ultimately do the things we do...for good and for ill. Sapolsky builds on this understanding to wrestle with some of our deepest and thorniest questions relating to tribalism and xenophobia, hierarchy and competition, morality and free will, and war and peace. Wise, humane, often very funny, Behave is a towering achievement, powerfully humanizing, and downright heroic in its own right.