NeuroTribes: The Legacy of Autism and the Future of Neurodiversity


Steve Silberman - 2015
      Along the way, he reveals the untold story of Hans Asperger, the father of Asperger’s syndrome, whose “little professors” were targeted by the darkest social-engineering experiment in human history; exposes the covert campaign by child psychiatrist Leo Kanner to suppress knowledge of the autism spectrum for fifty years; and casts light on the growing movement of "neurodiversity" activists seeking respect, support, technological innovation, accommodations in the workplace and in education, and the right to self-determination for those with cognitive differences.

Mind Wide Open: Your Brain and the Neuroscience of Everyday Life


Steven Johnson - 1999
    He asks: How do we "read" other people?What is the neurochemistry behind love and sex?What does it mean that the brain is teeming with powerful chemicals closely related to recreational drugs?Why does music move us to tears?Where do breakthrough ideas come from? Johnson answers these and many more questions arising from the events of our everyday lives. You do not have to be a neuroscientist to wonder, for example, why do you smile? And why do you sometimes smile inappropriately, even if you don't want to? How do others read your inappropriate smile? How does such interplay occur neurochemically, and what, if anything, can you do about it? Fascinating and rewarding, Mind Wide Open speaks to brain buffs, self-obsessed neurotics, barstool psychologists, mystified parents, grumpy spouses, exasperated managers, and anyone who enjoys speculating and gossiping about the motivations and behaviors of other human beings. Steven Johnson shows us the transformative power of understanding brain science and offers new modes of introspection and tools for better parenting, better relationships, and better living.

Connectome: How the Brain's Wiring Makes Us Who We Are


Sebastian Seung - 2012
    Is it in our genes? The structure of our brains? Our genome may determine our eye color and even aspects of our personality. But our friendships, failures, and passions also shape who we are. The question is: how?Sebastian Seung, a dynamic professor at MIT, is on a quest to discover the biological basis of identity. He believes it lies in the pattern of connections between the brain’s neurons, which change slowly over time as we learn and grow. The connectome, as it’s called, is where our genetic inheritance intersects with our life experience. It’s where nature meets nurture.Seung introduces us to the dedicated researchers who are mapping the brain’s connections, neuron by neuron, synapse by synapse. It is a monumental undertaking—the scientific equivalent of climbing Mount Everest—but if they succeed, it could reveal the basis of personality, intelligence, memory, and perhaps even mental disorders. Many scientists speculate that people with anorexia, autism, and schizophrenia are "wired differently," but nobody knows for sure. The brain’s wiring has never been clearly seen.In sparklingly clear prose, Seung reveals the amazing technological advances that will soon help us map connectomes. He also examines the evidence that these maps will someday allow humans to "upload" their minds into computers, achieving a kind of immortality.Connectome is a mind-bending adventure story, told with great passion and authority. It presents a daring scientific and technological vision for at last understanding what makes us who we are. Welcome to the future of neuroscience.

Behave: The Biology of Humans at Our Best and Worst


Robert M. Sapolsky - 2017
    Sapolsky's storytelling concept is delightful but it also has a powerful intrinsic logic: he starts by looking at the factors that bear on a person's reaction in the precise moment a behavior occurs, and then hops back in time from there, in stages, ultimately ending up at the deep history of our species and its evolutionary legacy.And so the first category of explanation is the neurobiological one. A behavior occurs--whether an example of humans at our best, worst, or somewhere in between. What went on in a person's brain a second before the behavior happened? Then Sapolsky pulls out to a slightly larger field of vision, a little earlier in time: What sight, sound, or smell caused the nervous system to produce that behavior? And then, what hormones acted hours to days earlier to change how responsive that individual is to the stimuli that triggered the nervous system? By now he has increased our field of vision so that we are thinking about neurobiology and the sensory world of our environment and endocrinology in trying to explain what happened.Sapolsky keeps going: How was that behavior influenced by structural changes in the nervous system over the preceding months, by that person's adolescence, childhood, fetal life, and then back to his or her genetic makeup? Finally, he expands the view to encompass factors larger than one individual. How did culture shape that individual's group, what ecological factors millennia old formed that culture? And on and on, back to evolutionary factors millions of years old.The result is one of the most dazzling tours d'horizon of the science of human behavior ever attempted, a majestic synthesis that harvests cutting-edge research across a range of disciplines to provide a subtle and nuanced perspective on why we ultimately do the things we do...for good and for ill. Sapolsky builds on this understanding to wrestle with some of our deepest and thorniest questions relating to tribalism and xenophobia, hierarchy and competition, morality and free will, and war and peace. Wise, humane, often very funny, Behave is a towering achievement, powerfully humanizing, and downright heroic in its own right.

The Master and His Emissary: The Divided Brain and the Making of the Western World


Iain McGilchrist - 2009
    In a book of unprecedented scope, McGilchrist draws on a vast body of recent brain research, illustrated with case histories, to reveal that the difference is profound—not just this or that function, but two whole, coherent, but incompatible ways of experiencing the world. The left hemisphere is detail oriented, prefers mechanisms to living things & is inclined to self-interest. The right hemisphere has greater breadth, flexibility & generosity. This division helps explain the origins of music & language, & casts new light on the history of philosophy, as well as on some mental illnesses. The 2nd part of the book takes a journey thru the history of Western culture, illustrating the tension between these two worlds as revealed in the thought & belief of thinkers & artists, from Aeschylus to Magritte. He argues that, despite its inferior grasp of reality, the left hemisphere is increasingly taking precedence in the modern world, with potentially disastrous consequences.List of IllustrationsAcknowledgmentsIntroductionAsymmetry and the brain --What do the two hemispheres 'do'? --Language, truth and music --The nature of the two worlds --The primacy of the right hemisphere --The triumph of the left hemisphere --Imitation and the evolution of culture --The ancient world --The Renaissance and the Reformation --The Enlightenment --Romanticism and the Industrial Revolution --The modern and post-modern worldsConclusionNotes BibliographyIndex

Brain Bugs: How the Brain's Flaws Shape Our Lives


Dean Buonomano - 2011
    Our memory is unreliable; we can't multiply large sums in our heads; advertising manipulates our judgment; we tend to distrust people who are different from us; supernatural beliefs and superstitions are hard to shake; we prefer instant gratification to long-term gain; and what we presume to be rational decisions are often anything but. Drawing on striking examples and fascinating studies, neuroscientist Dean Buonomano illuminates the causes and consequences of these "bugs" in terms of the brain's innermost workings and their evolutionary purposes. He then goes one step further, examining how our brains function-and malfunction-in the digital, predator-free, information-saturated, special effects-addled world that we have built for ourselves. Along the way, Brain Bugs gives us the tools to hone our cognitive strengths while recognizing our inherent weaknesses.

Opening Skinner's Box: Great Psychological Experiments of the Twentieth Century


Lauren Slater - 2004
    F. Skinner and the legend of a child raised in a box, Slater takes us from a deep empathy with Stanley Milgram's obedience subjects to a funny and disturbing re-creation of an experiment questioning the validity of psychiatric diagnosis. Previously described only in academic journals and textbooks, these often daring experiments have never before been narrated as stories, chock-full of plot, wit, personality, and theme.

Unthinkable: What the World's Most Extraordinary Brains Can Teach Us About Our Own


Helen Thomson - 2018
    We take for granted that we can remember, feel emotion, navigate, empathize, and understand the world around us, but how would our lives change if these abilities were dramatically enhanced--or disappeared overnight?Helen Thomson has spent years traveling the world, tracking down incredibly rare brain disorders. In Unthinkable she tells the stories of nine extraordinary people she encountered along the way. From the man who thinks he's a tiger to the doctor who feels the pain of others just by looking at them to a woman who hears music that’s not there, their experiences illustrate how the brain can shape our lives in unexpected and, in some cases, brilliant and alarming ways.Story by remarkable story, Unthinkable takes us on an unforgettable journey through the human brain. Discover how to forge memories that never disappear, how to grow an alien limb, and how to make better decisions. Learn how to hallucinate and how to make yourself happier in a split second. Find out how to avoid getting lost, how to see more of your reality, even how exactly you can confirm you are alive. Think the unthinkable.

The Man Who Couldn't Stop


David Adam - 2014
    In this captivating fusion of science, history and personal memoir, writer David Adam explores the weird thoughts that exist within every mind, and how they drive millions of us towards obsessions and compulsions.David has suffered from OCD for twenty years, and The Man Who Couldn’t Stop is his unflinchingly honest attempt to understand the condition and his experiences. What might lead an Ethiopian schoolgirl to eat a wall of her house, piece by piece; or a pair of brothers to die beneath an avalanche of household junk that they had compulsively hoarded? At what point does a harmless idea, a snowflake in a clear summer sky, become a blinding blizzard of unwanted thoughts? Drawing on the latest research on the brain, as well as historical accounts of patients and their treatments, this is a book that will challenge the way you think about what is normal, and what is mental illness.Told with fierce clarity, humour and urgent lyricism, this extraordinary book is both the haunting story of a personal nightmare, and a fascinating doorway into the darkest corners of our minds.

The Language Instinct: How the Mind Creates Language


Steven Pinker - 1994
    With deft use of examples of humor and wordplay, Steven Pinker weaves our vast knowledge of language into a compelling story: language is a human instinct, wired into our brains by evolution. The Language Instinct received the William James Book Prize from the American Psychological Association and the Public Interest Award from the Linguistics Society of America. This edition includes an update on advances in the science of language since The Language Instinct was first published.

The Seven Sins of Memory: How the Mind Forgets and Remembers


Daniel L. Schacter - 2001
    Schacter explores instances of what we would consider memory failure—absent-mindedness, transience, blocking, misattribution, suggestibility, bias, and persistence—and suggests instead that these miscues are actually indications that memory is functioning as designed. Drawing from vivid scientific research and creative literature, as well as high-profile events in which memory has figured significantly (Bill Clinton's grand jury testimony, for instance), The Seven Sins of Memory provides a more nuanced understanding of how memory and the mind influence each other and shape our lives.

Never Enough: The Neuroscience and Experience of Addiction


Judith Grisel - 2019
    With more than one in every five people over the age of fourteen addicted, drug abuse has been called the most formidable health problem worldwide. If we are not victims ourselves, we all know someone struggling with the merciless compulsion to alter their experience by changing how their brain functions.Drawing on years of research--as well as personal experience as a recovered addict--researcher and professor Judy Grisel has reached a fundamental conclusion: for the addict, there will never be enough drugs. The brain's capacity to learn and adapt is seemingly infinite, allowing it to counteract any regular disruption, including that caused by drugs. What begins as a normal state punctuated by periods of being high transforms over time into a state of desperate craving that is only temporarily subdued by a fix, explaining why addicts are unable to live either with or without their drug. One by one, Grisel shows how different drugs act on the brain, the kind of experiential effects they generate, and the specific reasons why each is so hard to kick.Grisel's insights lead to a better understanding of the brain's critical contributions to addictive behavior, and will help inform a more rational, coherent, and compassionate response to the epidemic in our homes and communities.

Proust and the Squid: The Story and Science of the Reading Brain


Maryanne Wolf - 2007
    Every new reader's brain possesses the extraordinary capacity to rearrange itself beyond its original abilities in order to understand written symbols. But how does the brain learn to read? As world-renowned cognitive neuroscientist and scholar of reading Maryanne Wolf explains in this impassioned book, we taught our brain to read only a few thousand years ago, and in the process changed the intellectual evolution of our species.Wolf tells us that the brain that examined tiny clay tablets in the cuneiform script of the Sumerians is configured differently from the brain that reads alphabets or of one literate in today's technology.There are critical implications to such an evolving brain. Just as writing reduced the need for memory, the proliferation of information and the particular requirements of digital culture may short-circuit some of written language's unique contributions—with potentially profound consequences for our future.Turning her attention to the development of the individual reading brain, Wolf draws on her expertise in dyslexia to investigate what happens when the brain finds it difficult to read. Interweaving her vast knowledge of neuroscience, psychology, literature, and linguistics, Wolf takes the reader from the brains of a pre-literate Homer to a literacy-ambivalent Plato, from an infant listening to Goodnight Moon to an expert reader of Proust, and finally to an often misunderstood child with dyslexia whose gifts may be as real as the challenges he or she faces.As we come to appreciate how the evolution and development of reading have changed the very arrangement of our brain and our intellectual life, we begin to realize with ever greater comprehension that we truly are what we read. Ambitious, provocative, and rich with examples, Proust and the Squid celebrates reading, one of the single most remarkable inventions in history. Once embarked on this magnificent story of the reading brain, you will never again take for granted your ability to absorb the written word.

The Other Brain: From Dementia to Schizophrenia, How New Discoveries about the Brain Are Revolutionizing Medicine and Science


R. Douglas Fields - 2008
    The Other Brain is the story of glia, which make up approximately 85 percent of the cells in the brain. Long neglected as little more than cerebral packing material ("glia" means glue), glia are sparking a revolution in brain science.Glia are completely different from neurons, the brain cells that we are familiar with. Scientists are discovering that glia have their own communication network, which operates in parallel to the more familiar communication among neurons. Glia provide the insulation for the neurons, and glia even regulate the flow of information between neurons.But it is the potential breakthroughs for medical science that are the most exciting frontier in glia research today. Diseases such as brain cancer and multiple sclerosis are caused by diseased glia. Glia are now believed to play an important role in such psychiatric illnesses as schizophrenia and depression, and in neurodegenerative diseases such as Parkinson's and Alzheimer's. They are linked to infectious diseases such as HIV and prion disease (mad cow disease, for example) and to chronic pain. Scientists have discovered that glia repair the brain and spinal cord after injury and stroke. The more we learn about these cells that make up the "other" brain, the more important they seem to be.Written by a neuroscientist who is a leader in the research to reveal the secrets of these brain cells, The Other Brain offers a firsthand account of science in action. It takes us into the laboratories where important discoveries are being made, and it explains how scientists are learning that glial cells come in different types, with different capabilities. It tells the story of glia research from its origins to the most recent discoveries and gives readers a much more complete understanding of how the brain works and where the next breakthroughs in brain science and medicine are likely to come.

Cure: A Journey into the Science of Mind Over Body


Jo Marchant - 2016
    Recently, however, serious scientists from a range of fields have been uncovering evidence that our thoughts, emotions and beliefs can ease pain, heal wounds, fend off infection and heart disease and even slow the progression of AIDS and some cancers.In Cure, award-winning science writer Jo Marchant travels the world to meet the physicians, patients and researchers on the cutting edge of this new world of medicine. We learn how meditation protects against depression and dementia, how social connections increase life expectancy and how patients who feel cared for recover from surgery faster. We meet Iraq war veterans who are using a virtual arctic world to treat their burns and children whose ADHD is kept under control with half the normal dose of medication. We watch as a transplant patient uses the smell of lavender to calm his hostile immune system and an Olympic runner shaves vital seconds off his time through mind-power alone.Drawing on the very latest research, Marchant explores the vast potential of the mind's ability to heal, lays out its limitations and explains how we can make use of the findings in our own lives. With clarity and compassion, Cure points the way towards a system of medicine that treats us not simply as bodies but as human beings.