Some of these drugs are truly transformative, offering major improvements in how long patients live or how they feel--but what is often missing from the popular narrative is that, far too often, these new drugs have marginal or minimal benefits. Some are even harmful. In Malignant, hematologist-oncologist Dr. Vinayak K. Prasad writes about the many sobering examples of how patients are too often failed by cancer policy and by how oncology is practiced. Throughout this work, Prasad illuminates deceptive practices which- promote novel cancer therapies long before credible data are available to support such treatment; and- exaggerate the potential benefits of new therapies, many of which cost thousands and in some cases hundreds of thousands of dollars.Prasad then critiques the financial conflicts of interest that pervade the oncology field, the pharmaceutical industry, and the US Food and Drug administration.This is a book about how the actions of human beings--our policies, our standards of evidence, and our drug regulation--incentivize the pursuit of marginal or unproven therapies at lofty and unsustainable prices. Prasad takes us through how cancer trials are conducted, how drugs come to market, and how pricing decisions are made, asking how we can ensure that more cancer drugs deliver both greater benefit and a lower price. Ultimately, Prasad says,- more cancer clinical trials should measure outcomes that actually matter to people with cancer;- patients on those trials should look more like actual global citizens;- we need drug regulators to raise, not perpetually lower, the bar for approval; and- we need unbiased patient advocates and experts.This well-written, opinionated, and engaging book explains what we can do differently to make serious and sustained progress against cancer--and how we can avoid repeating the policy and practice mistakes of the past.

    So often, we take our bodies for granted. We’re rarely curious about how they work and what we can do to make them work better. In The Body, Bill Bryson takes you on a tour inside your body so you can gain a better understanding of how it functions and its amazing ability to heal itself. At the times you doubt yourself, or think of yourself as less than wonderful, this summary of The Body will remind you of the miracle you truly are.

    Covering Sid's early years in South Africa and life as a ladies' hairdresser, his obsession with gambling and women, his questioning by Scotland Yard in a murder case, Hancock's Half Hour and the Carry On films, and Sid's death on stage at the age of 63, Cliff Goodwin reveals the amazing truth behing the legend.

    However, the human interaction between patient and care giver is still the essential foundation of healing. “I’m Here” is a personal narrative from the patient’s perspective. Filled with practical advice, packed with humor and overflowing with appreciation, Marcus Engel encourages health care professionals to practice compassionate communications in all its forms.“Marcus’ books and keynote presentation has left an unforgettable impression on our nursing staff. It’s an invaluable reminder of why we do, what we do.”-Dee Evans, Driscoll Children’s Hospital, Corpus Christi, TX“I’m Here” should be required reading for all health practitioners. Marcus’ personal experience of being a patient and his insights into what constitutes compassionate care are marvelous and right on.”-Dr. Norma Stephens Hannigan, Assistant Professor of Clinical Nursing Diplomate of Comprehensive Care, Columbia University in the City of New York. -Professional speaker and author Marcus Engel is considered an expert in communicating the patient’s perspective, and inspiring health care professionals to excellence. Marcus speaks from the heart. After being blinded and suffering catastrophic injuries at the hands of a drunk driver, he endured years of hospitalization, rehab and recovery. Marcus is the author of “After This… An Inspirational Journey for All the Wrong Reasons” and “The Other End of the Stethoscope: 33 Insights for Excellent Patient Care.”

    If you, or a friend or family member, is diagnosed with Bipolar, or if you suspect that someone you know may have Bipolar, this book is a fantastic first port of call for advice and support. Written in an extremely helpful question and answer format, this comprehensive and compassionate guide draws on a broad range of expert opinion, the very latest research, and personal experience to explore and explain everything that someone who has bipolar, friend, relative or carer might want to know about Bipolar Disorder. Including numerous real-life case studies and a full list of support organisations and internet resources around the world, this handy blend of advice and insight will answer all your questions, from how to recognise the symptoms to how to explain to a child that their parent has been diagnosed.

    The fastest-growing segment of the population, those beyond the age of fifty, are no longer content to simply cope with the losses of age. Mental acuity and vitality are becoming a life-long pursuit. Now, the science of the mind is catching up with the Baby Boom generation. In this landmark book, renowned psychiatrist Gene Cohen challenges the long-held belief that our brain power inevitably declines as we age, and shows that there are actually positive changes taking place in our minds. Based on the latest studies of the brain, as well as moving stories of men and women in the second half of life, The Mature Mind reveals for the first time how we can continue to grow and flourish. Cohen's groundbreaking theory-the first to elaborate on the psychology of later life-describes how the mind gives us "inner pushes" and creates new opportunities for positive change throughout adult life. He shows how we can jump-start that growth at any age and under any circumstances, fine-tuning as we go, actively building brain reserves and new possibilities. The Mature Mind offers a profoundly different and intriguing look at ourselves, challenging old assumptions, raising bold new questions, and providing exciting answers grounded in science and the realities of everyday life.

    Now, America finds itself cash poor, and to a great extent power follows money. In The End of Influence, renowned economic analysts Stephen S. Cohen and J. Bradford DeLong explore the grave consequences this loss will have for America's place in the world. America, Cohen and DeLong argue, will no longer be the world's hyperpower. It will no longer wield soft cultural power or dictate a monolithic foreign policy. More damaging, though, is the blow to the world's ability to innovate economically, financially, and politically. Cohen and DeLong also explore American's complicated relationship with China, the misunderstood role of sovereign wealth funds, and the return of state-led capitalism. An essential read for anyone interested in how global economics and finance interact with national policy, The End of Influence explains the far-reaching and potentially long-lasting but little-noted consequences of our great fiscal crisis.

    It is based on 10 years of research and experiments to figure out what can increase the personal energy of an average lazy person several times. Elements of this system are used by the most energetic people in the world including entrepreneurs, athletes and children. You will gain numerous insights and learn energy techniques accompanied by engaging stories, scientific researches and real-life examples. The concepts of the system are aimed at changing your mindset, maximizing your personal energy and increasing the amount of happy moments in your life. Once you become more energetic you may feel like you have a jet engine inside and can accomplish within a day more than an average person can within a week.

    It is made up of both the long-term chronically poor and new working poor—the tens of millions of victims of a broken economy and an ever more dysfunctional political system. In many ways, for the majority of Americans, financial insecurity has become the new norm.The American Way of Poverty shines a light on this travesty. Sasha Abramsky brings the effects of economic inequality out of the shadows and, ultimately, suggests ways for moving toward a fairer and more equitable social contract. Exploring everything from housing policy to wage protections and affordable higher education, Abramsky lays out a panoramic blueprint for a reinvigorated political process that, in turn, will pave the way for a renewed War on Poverty.It is, Harrington believed, a moral outrage that in a country as wealthy as America, so many people could be so poor. Written in the wake of the 2008 financial collapse, in an era of grotesque economic extremes, The American Way of Poverty brings that same powerful indignation to the topic.

    The word conjures up images of horrific diseases sweeping the globe and killing everyone in their path. But such highly lethal illnesses almost never create pandemics. The reality is deadly serious but far more subtle.In Pandemics: What Everyone Needs to Know�, Peter Doherty, who won the Nobel Prize for his work on how the immune system recognizes virus-infected cells, offers an essential guide to one of the truly life-or-death issues of our age. In concise, question-and-answer format, he explains the causes of pandemics, how they can be counteracted with vaccines and drugs, and how we can better prepare for them in the future. Doherty notes that the term "pandemic" refers not to a disease's severity but to its ability to spread rapidly over a wide geographical area. Extremely lethal pathogens are usually quickly identified and confined. Nevertheless, the rise of high-speed transportation networks and the globalization of trade and travel have radically accelerated the spread of diseases. A traveler from Africa arrived in New York in 1999 carrying the West Nile virus; one mosquito bite later, it was loose in the ecosystem. Doherty explains how the main threat of a pandemic comes from respiratory viruses, such as influenza and SARS, which disseminate with incredible speed through air travel. The climate disruptions of global warming, rising population density, and growing antibiotic resistance all complicate efforts to control pandemics. But Doherty stresses that pandemics can be fought effectively. Often simple health practices, especially in hospitals, can help enormously. And research into the animal reservoirs of pathogens, from SARS in bats to HIV in chimpanzees, show promise for our prevention efforts.Calm, clear, and authoritative, Peter Doherty's Pandemics is one of the most critically important additions to the What Everyone Needs to Know� series.What Everyone Needs to Know� is a registered trademark of Oxford University Press.

    While concepts like Sanskritization and Westernization have helped the understanding of complex, often seemingly contradictory trends in society, Prof. Srinivas' essay on the study of one's own society continue to engage scholars, opening the way to an understanding of sociological writing itself as a text. This revised edition of the 1966 original includes these classic essays, as also an appendix where Prof. Srinivas deals with the problem of changing values in Indian society today.

    Too bad. Because medicine isn't an industry, it's practically witchcraft. Despite the growth of big pharma, HMOs, and hospital chains, medicine remains the isolated work of individual doctors—and the system is going broke fast.So why is Andy Kessler—the man who told you outrageous stories of Wall Street analysts gone bad in Wall Street Meat and tales from inside a hedge fund in Running Money—poking around medicine for the next big wave of technology?It's because he smells change coming. Heart attacks, strokes, and cancer are a huge chunk of medical spending, yet there's surprisingly little effort to detect disease before it's life threatening. How lame is that—especially since the technology exists today to create computer-generated maps of your heart and colon?Because it's too expensive—for now. But Silicon Valley has turned computing, telecom, finance, music, and media upside down by taking expensive new technologies and making them ridiculously cheap. So why not the $1.8 trillion health care business, where the easiest way to save money is to stop folks from getting sick in the first place?Join Kessler's bizarre search for the next big breakthrough as he tries to keep from passing out while following cardiologists around, cracks jokes while reading mammograms, and watches twitching mice get injected with radioactive probes. Looking for a breakthrough, Kessler even selflessly pokes, scans, and prods himself.CT scans of your heart will identify problems before you have a heart attack or stroke; a nanochip will search your blood for cancer cells--five years before they grow uncontrollably and kill you; and baby boomers can breathe a little easier because it's all starting to happen now.Your doctor can't be certain what's going on inside your body, but technology will. Embedding the knowledge of doctors in silicon will bring a breakout technology to health care, and we will soon see an end of medicine as we know it.

    - Book Review Editor of the journal "Modern Pathology," the official journal of the United States-Canadian Academy of Pathology and prestigious best-selling author. This is the 5th edition of a book that has already established itself as the classic pathology textbook in India. This new edition has been updated, and improved to meet the highest standards of quality and information now required by pathology courses around the world. Editorially this new edition carries particular emphasis on molecular pathology and genetics in the pathogenesis of various diseases, and the pathological discussions of each organ or system is preceded with a short description of its structure and function. The material is integrated with extensive page cross references between chapters and the whole book has been thoroughly re-edited, with new images, illustrations and line drawings. The book is accompanied by the free student revision aid "Pathology - Quick Review and MCQs" and therefore, together as a package, "Textbook of Pathology, 5E" will be a major contribution to the required reading of undergraduate medical students worldwide.

    Now, a former Senior Editor for "Maxim gives a crash course on the men behind our favorite labels, including:

    Orphaned as a teenager, he came to America in search of an education, a home, and the war that would at last bring him fame and honor. As George Washington’s most trusted aide, Hamilton helped to win the American Revolution—but after the war, his enemies lost no time accusing him of trying to sell his country back to the British. He was the most powerful member of Washington’s presidential cabinet—so why did Adams and Jefferson hate him so much?In this book, you will learn how the author of the Federalist Papers and the first Secretary of the Treasury nearly ruined his career by fighting duels, seducing women, and getting involved in America’s first sex scandal. The duel that killed Alexander Hamilton is the most famous duel in American history, but you’ll have to come up with your own answer to its greatest mystery: who shot first, Hamilton or Burr?