They are the powerhouses of our cells, essential for the production and management of energy at cell level. Dr Sarah Myhill, together with Dr John McLaren Howard of Acumen Laboratories and Dr Norman Booth of Mansfield College Oxford, has spent many years studying the relationship between their malfunction and the commonest problem seen by GPs in the UK – fatigue. Their research findings have been published in three scientific papers in the International Journal of Clinical and Experimental Medicine, in 2009, 2012 and 2013. These studies showed that poor functioning of the mitochondria is the central problem in CFS. Patients with the worst mitochondrial function had the worst fatigue and vice versa. This is solid scientific evidence that CFS is a problem with mitochondria and has allowed the objective measurement of fatigue for the first time. With the publication of the third study, which showed that mitochondrial function tests and symptoms improved in patients who took measures to address their mitochondrial problems, Dr Myhill was ready to write this book. Here she explains the importance of healthy mitochondria, how we can measure their functioning and what we can do to keep them healthy, or restore them to health if problems arise. CFS is all in our cells, not in our minds!

    This text introduces the basic mathematical and computational methods of theoretical neuroscience and presents applications in a variety of areas including vision, sensory-motor integration, development, learning, and memory.The book is divided into three parts. Part I discusses the relationship between sensory stimuli and neural responses, focusing on the representation of information by the spiking activity of neurons. Part II discusses the modeling of neurons and neural circuits on the basis of cellular and synaptic biophysics. Part III analyzes the role of plasticity in development and learning. An appendix covers the mathematical methods used, and exercises are available on the book's Web site.

    Are you thinking about getting into triathlon or attempting your first race? Maybe you’re curious about this whole “Triathlon” thing and want to know if its right for you?If you've ever thought about doing a triathlon, you’re in the right place . Triathlon: the Beginners Guide Will Be Your Trusted Guide Triathlon can be confusing.  Let me help you get started. Don’t be intimidated by skinny 20-somethings squeezed into lycra. Don’t rush into dangerous amounts of joint-pounding training; risking your health. Don’t be fooled into buying tons of expensive and unnecessary equipment. The Beginners Guide will act as your road-map to Triathlon success It covers every aspect of your triathlon, including: which Triathlon distance is right for you how to swim and get over the fear of swimming in open-water, away from the safety and familiarity of your local pool. becoming a fast (and safe) cyclist, without spending thousands of dollars on a professional-grade bike how to run after you’ve just finished an intense bike ride what to look for in a triathlon training plan, and how to tell if you should tear yours up on the spot what you need to eat and drink; before, during and after your race how to put it all together in the intense “transition area” and how to survive race day nerves and the complex logistics of a triathlon race site. I’ll Also Reveal these Nuggets of Triathlon Gold; Earned from Over 25 Years of Triathlon the same “Six Periods of Training” I use with my $1000 per month one-on-one students the simple truth about structuring your Triathlon training . . . no math formula or science PhD required why “standard” advice about open-water swimming will leave you gasping for air while others swim over the top of you the most powerful cure for fear of swimming ever known . . . and why it’s easier to fix than you’ve ever thought possible the single little-known secret of triathlon training to dramatically reduce your risk of injury . . . by up to as much as 90% the only list you’ll ever need for all your Triathlon planning why most Triathlon coaches are 100% wrong in the way they approach race day how to avoid the embarrassing mistakes even veteran triathletes make on race day Start Your Triathlon Journey Today Triathlons the Beginners Guide is everything a new triathl

     World War Two is at its height. A formidable flyer and outstanding marksman, at twenty Charles Hubbard stands out amongst his comrades. Shooting down an enemy aircraft before even being sent to France, he quickly gains a reputation as an Ace before being himself shot down. Returning to England as the Nazi push continues, Hubbard continues to gain renown as he becomes embroiled in the Battle of Britain before being posted to North Africa. Soon he finds himself fighting a very different war to the one he is used to, a war not just against the Germans and Italians but against the desert itself. In an area known simply as The Cauldron, Hubbard’s bravery and moral stamina are pushed to the very limit time and again. Teetering on the verge of breakdown, his men are looking up to him to lead them on towards victory. Hubbard does not know if he has the strength left within himself to rise up once more and overcome his fears… ‘The Cauldron’ is a thrilling World War Two adventure from Richard Townshend Bickers. Praise for Richard Townshend Bickers: ‘A valuable history of the air war that began it all… by an ex-flyer of the Second World War who has a genuine feeling for the feats of his predecessors’ - THE BIRMINGHAM POST ‘His sympathy with the fighting man (and woman) shines out of every page’ - LIVERPOOL DAILY POST Richard Townshend Bickers volunteered for the RAF on the outbreak of the second world war and served, with a Permanent Commission, for eighteen years. He wrote a range of military fiction and non-fiction books, including ‘Torpedo Attack’, ‘My Enemy Came Nigh’, ‘Bombing Run’ and ‘Summer of No Surrender’. Endeavour Press is the UK's leading independent digital publisher. For more information on our titles please sign up to our newsletter at www.endeavourpress.com. Each week you will receive updates on free and discounted ebooks. Follow us on Twitter: @EndeavourPress and on Facebook via http://on.fb.me/1HweQV7. We are always interested in hearing from our readers. Endeavour Press believes that the future is now.

    The meaning of the business process diagram is the same, regardless of the tool used to create it. But creating models that are correct, complete, and clear demands more than a dictionary of BPMN shapes and symbols. It also requires a methodology for translating process logic consistently into the diagram. And it requires a measure of modeling style as well, conventions that ensure that the process logic is unambiguous from the diagram by itself. In short, "good BPMN" requires a disciplined approach called "method and style."In this book, Bruce Silver explains which BPMN elements process modelers need to understand, in two levels, including exactly where and how to use each element. Level 1 (the Descriptive modeling subclass of BPMN 2.0) is a palette of shapes and symbols largely carried over from traditional flowcharting. Level 2 (the Analytic subclass) expands the palette to be able to describe event-triggered behavior, critical to modeling exception handling.The book explains the real meaning of BPMN's most basic concepts - like activity, process, and end state - essential to using the language correctly, and provides a step-by-step methodology for going from a blank page to a complete end-to-end BPMN model, developed from the top down in a hierarchical structure. From the top-level diagram you can see on a single page exactly how the process starts, its possible end states, what the instance represents, and communications with the Customer, service providers, and other processes. From there you can drill down to see the details of any part of the process. Thie popular first edition of this book was published in 2009 based on the draft BPMN 2.0 specification. This second edition is based on the final BPMN 2.0 specification. Although the diagram elements have changed little since the first edition, both the methodology and style sections have been completely rewritten.The second half of the book, the BPMN Implementer's Guide, is completely new. It puts the focus on the XML serialization of the diagram, for both non-executable and executable process models. It details the BPMN 2.0 metamodel and XML Schema, and describes the BPMN-I Profile, a set of serialization rules that facilitate interchange of BPMN models in the Analytic subclass between tools. It also explains how BPMN 2.0 describes execution-related details, such as process data and data mapping, services, messages, and human task assignment, illustrated with an example executable process created in Bonita Open Solution. It concludes with guidelines for implementers on how to align executable design with business-oriented top-down process modeling.The book is lavishly illustrated with over 100 BPMN diagrams, and the BPMN Implementer's Guide section contains many XML examples as well.Bruce Silver is the leading provider of BPMN training and certification. He has been providing BPMN training since early 2007 and is regarded as an authority in the field.

    It is planned to give a solid basis of the structures and vocabulary of English. Each book contains material for about a year's work, the vocabulary rising to some 3,000 words.The Teacher's Books provide notes on each lesson, the vocabulary to be taught, supplementary grammatical material and answers to exercises.In this new edition some of the grammatical sections have been, rewritten and expanded, and parts of the text and many illustrations have been brought up to date. Fundamentally, however, the new edition remains the same as previous editions.

    In an instructive and conversational tone, Cody clearly explains how to program SAS, illustrating with one or more real-life examples and giving a detailed description of how the program works.

    

    Never before has a reference work of this scope been created to help both the experienced reader and the investigator or new convert understand this important book of scripture. It is like having a teacher beside you as you read and study. Maps, illustrations, photographs, pictures, outlines, and charts combine with the informative articles to enhance understanding and help parents, teachers, and leaders share the message of the Book of Mormon with their families and students. A must-have reference book for every Latter-day Saint library!

    It assumes no prior knowledge of linguistic theory and little of elementary grammar. It will suit students coming to syntactic theory for the first time either as graduates or undergraduates. It will also be useful forthose in fields such as computational science, artificial intelligence, or cognitive psychology who need a sound knowledge of current syntactic theory.

    is an American Board of Emergency Medicine certified ED doctor. His journey began in the mid-1970s, when he chose to pursue a career in medicine. In his youthful perspective, he came to regard doctors as the good guys, the ones who healed people and saved lives. He knew he’d be one of those good guys one day. Now, with a career spanning more than thirty years, he works as an emergency-room physician in North Carolina. In A License to Heal: Random Memories of an ER Doctor, Bentley describes the real world of emergency medicine from the viewpoint of a practicing physician. This memoir is filled with real-life stories of the ER, including life and death, triumph and tragedy. Meet a man named Solomon Darby, who spoke to long-dead relatives during his own near-death experience. Bentley also recalls the heartbreaking story of a young widow who desperately needed to understand and cope with the death of her husband. Amid the grief, there are also episodes of great humor and human comedy. In the dynamic world of emergency medicine, there is a great deal of pain, blood, and tragedy, but there is also hope, compassion, and excitement—for both the patients and the staff."

    

    An introductory chapter surveys the political, religious, and social world of the Gospels, methods of approaching early Christian texts, the genre of the Gospels, and the religious character of these writing. Included also are comments on the Gospels that are not found in the New Testament. Special features, including illustrations and more than two dozen special topics, enhance this convenient volume.

    This Study Guide was developed to meet the exacting requirements of today's Cisco certification candidates. In addition to the engaging and accessible instructional approach that has earned author Todd Lammle the "Best Study Guide Author" award in CertCities Readers' Choice Awards for two consecutive years, this updated fifth edition provides:In-depth coverage of every CCNA exam objective Expanded IP addressing and subnetting coverage More detailed information on EIGRP and OSPF Leading-edge exam preparation software Authoritative coverage of all exam objectives, including:Network planning & designing Implementation & operation LAN and WAN troubleshooting Communications technology

    In many churches, the primary objective of the church discipleship of people into mature followers of Jesus has been outsourced to programs and large-scale efforts to train and teach. But is that happening? Are people growing in spiritual depth and missional determination?Twenty-five years ago, the leaders of Randy Pope s rapidly growing church took serious stock of their own spiritual development and realized all of them had benefitted from a personal discipleship relationship that had helped them grow in their faith and discover where God was calling them to service. As a church, they decided to make personal discipleship their do-or-die aim: applying one person s real life to another s to accomplish something far bigger than that single life. Perimeter calls their approach life-on-life missional discipleship and Insourcing tells their story.Randy Pope writes for church leaders who recognize the value of discipleship and need practical ideas for reorienting church ministries around personal discipleship. Readers will be encouraged that a wide scale personal discipleship program is attainable for any church."