It intersects with Darwin’s theory of evolution, and collides with the horrors of Nazi eugenics in the 1940s. The gene transforms post-war biology. It reorganizes our understanding of sexuality, temperament, choice and free will. This is a story driven by human ingenuity and obsessive minds – from Charles Darwin and Gregor Mendel to Francis Crick, James Watson and Rosalind Franklin, and the thousands of scientists still working to understand the code of codes.This is an epic, moving history of a scientific idea coming to life, by the author of The Emperor of All Maladies. But woven through The Gene, like a red line, is also an intimate history – the story of Mukherjee’s own family and its recurring pattern of mental illness, reminding us that genetics is vitally relevant to everyday lives. These concerns reverberate even more urgently today as we learn to “read” and “write” the human genome – unleashing the potential to change the fates and identities of our children.Majestic in its ambition, and unflinching in its honesty, The Gene gives us a definitive account of the fundamental unit of heredity – and a vision of both humanity’s past and future.

    Richard Louis Miller discusses what is happening today in psychedelic medicine--and what will happen in the future--with top researchers and thinkers in this field, including Rick Doblin, Stanislav Grof, James Fadiman, Julie Holland, Dennis McKenna, David Nichols, Charles Grob, Phil Wolfson, Michael and Annie Mithoefer, Roland Griffiths, Katherine MacLean, and Robert Whitaker. Dr. Miller and his contributors cover the tumultuous history of early psychedelic research brought to a halt 50 years ago by the U.S. government as well as offering non-technical summaries of the most recent studies with MDMA, psilocybin, LSD, and ayahuasca. They explore the biochemistry of consciousness and the use of psychedelics for self-discovery and healing. They discuss the use of psilocybin for releasing fear in the terminally ill and the potential for MDMA-assisted psychotherapy in the treatment of PTSD. They examine Dr. Charles Grob’s research on the indigenous use and therapeutic properties of ayahuasca and Dr. Gabor Mate’s attempt to transport this plant medicine to a clinical setting with the help of Canada’s Department of National Health. Dr. Miller and his contributors explore the ongoing efforts to restore psychedelic therapies to the health field, the growing threat of overmedication by the pharmaceutical industry, and the links between psychiatric drugs and mental illness. They also discuss the newly shifting political climate and the push for new research, offering hope for an end to the War on Drugs and a potential renaissance of research into psychedelic medicines around the world.

    Yalom uncovers the mysteries, frustrations, pathos, and humor at the heart of the therapeutic encounter. In recounting his patients' dilemmas, Yalom not only gives us a rare and enthralling glimpse into their personal desires and motivations but also tells us his own story as he struggles to reconcile his all-too human responses with his sensibility as a psychiatrist. Not since Freud has an author done so much to clarify what goes on between a psychotherapist and a patient.

    In pursuit of these things, it is undeterred by emotion, fear, or morality. Dopamine is the source of our every urge, that little bit of biology that makes an ambitious business professional sacrifice everything in pursuit of success, or that drives a satisfied spouse to risk it all for the thrill of someone new. Simply put, it is why we seek and succeed; it is why we discover and prosper. Yet, at the same time, it’s why we gamble and squander. From dopamine’s point of view, it’s not the having that matters. It’s getting something—anything—that’s new. From this understanding—the difference between possessing something versus anticipating it—we can understand in a revolutionary new way why we behave as we do in love, business, addiction, politics, religion – and we can even predict those behaviors in ourselves and others. In The Molecule of More: How a Single Chemical in Your Brain Drives Love, Sex, and Creativity—and will Determine the Fate of the Human Race, George Washington University professor and psychiatrist Daniel Z. Lieberman, MD, and Georgetown University lecturer Michael E. Long present a potentially life-changing proposal: Much of human life has an unconsidered component that explains an array of behaviors previously thought to be unrelated, including why winners cheat, why geniuses often suffer with mental illness, why nearly all diets fail, and why the brains of liberals and conservatives really are different.

    A slip of the hand and life ebbs away.The balance between life and death is so delicate, and the heart surgeon walks that rope between the two. In the operating room there is no time for doubt. It is flesh, blood, rib-retractors and pumping the vital organ with your bare hand to squeeze the life back into it. An off-day can have dire consequences – this job has a steep learning curve, and the cost is measured in human life. Cardiac surgery is not for the faint of heart.Professor Stephen Westaby took chances and pushed the boundaries of heart surgery. He saved hundreds of lives over the course of a thirty-five year career and now, in his astounding memoir, Westaby details some of his most remarkable and poignant cases – such as the baby who had suffered multiple heart attacks by six months old, a woman who lived the nightmare of locked-in syndrome, and a man whose life was powered by a battery for eight years.A powerful, important and incredibly moving book, Fragile Lives offers an exceptional insight into the exhilarating and sometimes tragic world of heart surgery, and how it feels to hold someone’s life in your hands.

    Despite having no formal qualifications or experience, she found herself in palliative care. Over the years she spent tending to the needs of those who were dying, Bronnie’s life was transformed. Later, she wrote an Internet blog about the most common regrets expressed to her by the people she had cared for. The article, also called The Top Five Regrets of the Dying, gained so much momentum that it was read by more than three million people around the globe in its first year. At the requests of many, Bronnie now shares her own personal story. Bronnie has had a colourful and diverse past, but by applying the lessons of those nearing their death to her own life, she developed an understanding that it is possible for people, if they make the right choices, to die with peace of mind. In this book, she expresses in a heartfelt retelling how significant these regrets are and how we can positively address these issues while we still have the time. The Top Five Regrets of the Dying gives hope for a better world. It is a story told through sharing her inspiring and honest journey, which will leave you feeling kinder towards yourself and others, and more determined to live the life you are truly here to live. This delightful memoir is a courageous, life-changing book."

    In 1903, while on a three-day camping trip with President Theodore Roosevelt, he convinced the president of the importance of a national conservation program, and he is widely recognized for saving the Grand Canyon and Arizona's Petrified Forest. Muir's writing, based on journals he kept throughout his life, gives our generation a picture of an America still wild and unsettled only one hundred years ago. In The Wildernesss World of John Muir Edwin Way Teale has selected the best of Muir's writing from all of his major works—including My First Summer in the Sierra and Travels in Alaska—to provide a singular collection that provides to be "magnificent, thrilling, exciting, breathtaking, and awe-inspiring" (Kirkus Reviews).

    . . except himself. Out of control of his actions, Billy Milligan was a man tormented by twenty-four distinct personalities battling for supremacy over his body—a battle that culminated when he awoke in jail, arrested for the kidnap and rape of three women. In a landmark trial, Billy was acquitted of his crimes by reason of insanity caused by multiple personality—the first such court decision in history—bringing to public light the most remarkable and harrowing case of multiple personality ever recorded.Twenty-four people live inside Billy Milligan. Philip, a petty criminal; Kevin, who dealt drugs and masterminded a drugstore robbery; April, whose only ambition was to kill Billy's stepfather; Adalana, the shy, lonely, affection-starved lesbian who “used” Billy's body in the rapes that led to his arrest; David, the eight-year-old “keeper of pain”; and all of the others, including men, women, several children, both boys and girls, and the Teacher, the only one who can put them all together. You will meet each in this often shocking true story. And you will be drawn deeply into the mind of this tortured young man and his splintered, terrifying world.

    Laing explains how we all exist in the world as beings, defined by others who carry a model of us in their heads, just as we carry models of them in our heads. In later writings he often takes this to deeper levels, laboriously spelling out how "A knows that B knows that A knows that B knows..."! Our feelings and motivations derive very much from this condition of "being in the world" in the sense of existing for others, who exist for us. Without this we suffer "ontological insecurity", a condition often expressed in terms of "being dead" by people who are clearly still physically alive.This watershed work aimed to make madness comprehensible, and in doing so revolutionized the way we perceive mental illness. Using case studies of patients he had worked with, psychiatrist R. D. Laing argued that psychosis is not a medical condition, but an outcome of the 'divided self', or the tension between the two personas within us: one our authentic, private identity, and the other the false, 'sane' self that we present to the world. Laing's radical approach to insanity offered a rich existential analysis of personal alienation and made him a cult figure in the 1960s, yet his work was most significant for its humane attitude, which put the patient back at the centre of treatment. R.D. Laing (1927-1989), one of the best-known psychiatrists of modern times, was born in Glasgow, Scotland.This work is available on its own or as part of the 7 volume set iSelected Works of R. D. Laing

    These are the very same behaviors that typify good soldiering and foster a sense of belonging among troops, whether they’re fighting on the front lines or engaged in non-combat activities away from the action. Drawing from history, psychology, and anthropology, bestselling author Sebastian Junger shows us just how at odds the structure of modern society is with our tribal instincts, arguing that the difficulties many veterans face upon returning home from war do not stem entirely from the trauma they’ve suffered, but also from the individualist societies they must reintegrate into.A 2011 study by the Canadian Forces and Statistics Canada reveals that 78 percent of military suicides from 1972 to the end of 2006 involved veterans. Though these numbers present an implicit call to action, the government is only just taking steps now to address the problems veterans face when they return home. But can the government ever truly eliminate the challenges faced by returning veterans? Or is the problem deeper, woven into the very fabric of our modern existence? Perhaps our circumstances are not so bleak, and simply understanding that beneath our modern guises we all belong to one tribe or another would help us face not just the problems of our nation but of our individual lives as well.Well-researched and compellingly written, this timely look at how veterans react to coming home will reconceive our approach to veteran’s affairs and help us to repair our current social dynamic.

    Lieberman illuminates how these ongoing changes have brought many benefits, but also have created novel conditions to which our bodies are not entirely adapted, resulting in a growing incidence of obesity and new but avoidable diseases, including type-2 diabetes. He proposes that many of these chronic illnesses persist and in some cases are intensifying because of "dysevolution," a pernicious dynamic whereby only the symptoms rather than the causes of these maladies are treated. And finally—provocatively—he advocates the use of evolutionary information to help nudge, push, and sometimes oblige us to create a more salubrious environment.(With charts and line drawings throughout.)From the Hardcover edition.

    In his madness, the world was revealed to him as an enormous architecture of nerves, dominated by a predatory God. It became clear to Schreber that his personal crisis was implicated in what he called a "crisis in God's realm," one that had transformed the rest of humanity into a race of fantasms. There was only one remedy; as his doctor noted: Schreber "considered himself chosen to redeem the world, and to restore to it the lost state of Blessedness. This, however, he could only do by first being transformed from a man into a woman...."

    By demystifying the fantasies surrounding cancer, Sontag shows cancer for what it is--just a disease. Cancer, she argues, is not a curse, not a punishment, certainly not an embarrassment and, it is highly curable, if good treatment is followed.Almost a decade later, with the outbreak of a new, stigmatized disease replete with mystifications and punitive metaphors, Sontag wrote a sequel to Illness as Metaphor, extending the argument of the earlier book to the AIDS pandemic.These two essays now published together, Illness as Metaphor and AIDS and Its Metaphors, have been translated into many languages and continue to have an enormous influence on the thinking of medical professionals and, above all, on the lives of many thousands of patients and caregivers.

    And yet hope has never been more desperately needed.In this urgent book, Jane Goodall, the world's most famous living naturalist and Doug Abrams, internationally-bestselling author, explore--through intimate and thought-provoking dialogue--one of the most sought after and least understood elements of human nature: hope. In The Book of Hope, Jane focuses on her “Four Reasons for Hope”: The Amazing Human Intellect, The Resilience of Nature, The Power of Young People, and The Indomitable Human Spirit.Told through stories from a remarkable career and fascinating research, The Book of Hope touches on vital questions including: How do we stay hopeful when everything seems hopeless? How do we cultivate hope in our children? Filled with engaging dialogue and pictures from Jane’s storied career, The Book of Hope is a deeply personal conversation with one of the most beloved figures in today’s world.And for the first time, Jane tells the story of how she became a messenger of hope: from living through World War II, to her years in Gombe, to realizing she had to leave the forest to travel the world in her role as an advocate for environmental justice. She details the forces that shaped her hopeful worldview, her thoughts on her past, and her revelations about her next--and perhaps final--adventure.There is still hope, and this book will help guide us to it.

    These individuals all lost some part of what we think of as our self, but they then offer remarkable, sometimes heart-wrenching insights into what remains. One man cut off his own leg. Another became one with the universe.We are learning about the self at a level of detail that Descartes (“I think therefore I am”) could never have imagined. Recent research into Alzheimer’s illuminates how memory creates your narrative self by using the same part of your brain for your past as for your future. But wait, those afflicted with Cotard’s syndrome think they are already dead; in a way, they believe that “I think therefore I am not.” Who—or what—can say that? Neuroscience has identified specific regions of the brain that, when they misfire, can cause the self to move back and forth between the body and a doppelgänger, or to leave the body entirely. So where in the brain, or mind, or body, is the self actually located? As Ananthaswamy elegantly reports, neuroscientists themselves now see that the elusive sense of self is both everywhere and nowhere in the human brain.