We take for granted that we can remember, feel emotion, navigate, empathize, and understand the world around us, but how would our lives change if these abilities were dramatically enhanced--or disappeared overnight?Helen Thomson has spent years traveling the world, tracking down incredibly rare brain disorders. In Unthinkable she tells the stories of nine extraordinary people she encountered along the way. From the man who thinks he's a tiger to the doctor who feels the pain of others just by looking at them to a woman who hears music that’s not there, their experiences illustrate how the brain can shape our lives in unexpected and, in some cases, brilliant and alarming ways.Story by remarkable story, Unthinkable takes us on an unforgettable journey through the human brain. Discover how to forge memories that never disappear, how to grow an alien limb, and how to make better decisions. Learn how to hallucinate and how to make yourself happier in a split second. Find out how to avoid getting lost, how to see more of your reality, even how exactly you can confirm you are alive. Think the unthinkable.

    Sam Halpern, who is "like Socrates, but angrier, and with worse hair," has never minced words, and when Justin moved back home, he began to record all the ridiculous things his dad said to him:"That woman was sexy. . . . Out of your league? Son, let women figure out why they won't screw you. Don't do it for them.""Do people your age know how to comb their hair? It looks like two squirrels crawled on their heads and started fucking.""The worst thing you can be is a liar. . . . Okay, fine, yes, the worst thing you can be is a Nazi, but then number two is liar. Nazi one, liar two."More than a million people now follow Mr. Halpern's philosophical musings on Twitter, and in this book, his son weaves a brilliantly funny, touching coming-of-age memoir around the best of his quotes. An all-American story that unfolds on the Little League field, in Denny's, during excruciating family road trips, and, most frequently, in the Halperns' kitchen over bowls of Grape-Nuts, Sh*t My Dad Says is a chaotic, hilarious, true portrait of a father-son relationship from a major new comic voice.

    One day he was a doctor treating the dying, and the next he was a patient struggling to live. And just like that, the future he and his wife had imagined evaporated. When Breath Becomes Air chronicles Kalanithi's transformation from a naïve medical student "possessed," as he wrote, "by the question of what, given that all organisms die, makes a virtuous and meaningful life" into a neurosurgeon at Stanford working in the brain, the most critical place for human identity, and finally into a patient and new father confronting his own mortality. What makes life worth living in the face of death? What do you do when the future, no longer a ladder toward your goals in life, flattens out into a perpetual present? What does it mean to have a child, to nurture a new life as another fades away? These are some of the questions Kalanithi wrestles with in this profoundly moving, exquisitely observed memoir. Paul Kalanithi died in March 2015, while working on this book, yet his words live on as a guide and a gift to us all. "I began to realize that coming face to face with my own mortality, in a sense, had changed nothing and everything," he wrote. "Seven words from Samuel Beckett began to repeat in my head: 'I can't go on. I'll go on.'" When Breath Becomes Air is an unforgettable, life-affirming reflection on the challenge of facing death and on the relationship between doctor and patient, from a brilliant writer who became both.

    It also makes him enormously vulnerable. Eli lacks the innate skepticism that will help his peers navigate adolescence more safely—and vastly more successfully. Journalist Jennifer Latson follows Eli over three critical years of his life as his mother, Gayle, must decide whether to shield Eli entirely from the world and its dangers or give him the freedom to find his own way and become his own person. By intertwining Eli and Gayle’s story with the science and history of Williams syndrome, the book explores the genetic basis of behavior and the quirks of human nature. More than a case study of a rare disorder, however, The Boy Who Loved Too Much is a universal tale about the joys and struggles of raising a child, of growing up, and of being different.

    In The Dance of Life, developmental and stem-cell biologist Magdalena Zernicka-Goetz takes us to the front lines of efforts to understand the creation of a human life. She has spent two decades unraveling the mysteries of development, as a simple fertilized egg becomes a complex human being of forty trillion cells. Zernicka-Goetz's work is both incredibly practical and astonishingly vast: her groundbreaking experiments with mouse, human, and artificial embryo models give hope to how more women can sustain viable pregnancies. Set at the intersection of science's greatest powers and humanity's greatest concern, The Dance of Life is a revelatory account of the future of fertility -- and life itself.

    She believes that by shedding our armor, we can stop hiding, competing, striving for the mirage of perfection, and making motherhood, marriage, and friendship harder by pretending they’re not hard. In this one woman trying to love herself and others, readers find a wise and witty friend who will inspire them to forgive their own imperfections, make the most of their gifts, and commit to small acts of love that will change the world.

    Unable to stand, barely able to think, he waited for hours in an emergency room before being correctly diagnosed and rushed into surgery. Over the next few days, as he clung to life and the first light of a new year came through his window, he found himself reflecting on the fragility of health, not recognized in America as a human right but without which all rights and freedoms have no meaning.And that was before the pandemic. We have since watched American hospitals, long understaffed and undersupplied, buckling under waves of coronavirus patients. The federal government made matters worse through willful ignorance, misinformation, and profiteering. Our system of commercial medicine failed the ultimate test, and thousands of Americans died.In this eye-opening cri de coeur, Snyder traces the societal forces that led us here and outlines the lessons we must learn to survive. In examining some of the darkest moments of recent history and of his own life, Snyder finds glimmers of hope and principles that could lead us out of our current malaise. Only by enshrining healthcare as a human right, elevating the authority of doctors and medical knowledge, and planning for our children's future can we create an America where everyone is truly free.

    This book is that record. But it is also something else: maybe the funniest, most unsparing account of ordinary daily household life ever recorded, from the point of view of the man inside. The remarkable thing about this story isn’t that Lewis is so unusual. It’s that he is so typical. The only wonder is that his wife has allowed him to publish it.

    At first, she toughed it out through searing pain, taking sick days from work, unable to leave the bathroom or her bed. But when it became undeniable that something was seriously wrong, Miller gave in to family pressure and went to the hospital—beginning a yearslong nightmare of procedures, misdiagnoses, and life-threatening infections. Once she was finally correctly diagnosed with Crohn’s disease, Miller faced another battle: accepting that she will never get better.Today, an astonishing three in five adults in the United States suffer from a chronic disease—a percentage expected to rise post-Covid. Whether the illness is arthritis, asthma, Crohn's, diabetes, endometriosis, multiple sclerosis, ulcerative colitis, or any other incurable illness, and whether the sufferer is a colleague, a loved one, or you, these diseases have an impact on just about every one of us. Yet there remains an air of shame and isolation about the topic of chronic sickness. Millions must endure these disorders not only physically but also emotionally, balancing the stress of relationships and work amid the ever-present threat of health complications.Miller segues seamlessly from her dramatic personal experiences into a frank look at the cultural realities (medical, occupational, social) inherent in receiving a lifetime diagnosis. She offers hard-earned wisdom, solidarity, and an ultimately surprising promise of joy for those trying to make sense of it all.

    But in the modern world, the breast is changing. Breasts are getting bigger, arriving earlier, and attracting newfangled chemicals. Increasingly, the odds are stacked against us in the struggle with breast cancer, even among men. What makes breasts so mercurial—and so vulnerable?In this informative and highly entertaining account, intrepid science reporter Florence Williams sets out to uncover the latest scientific findings from the fields of anthropology, biology, and medicine. Her investigation follows the life cycle of the breast from puberty to pregnancy to menopause, taking her from a plastic surgeon’s office where she learns about the importance of cup size in Texas to the laboratory where she discovers the presence of environmental toxins in her own breast milk. The result is a fascinating exploration of where breasts came from, where they have ended up, and what we can do to save them.

     In a culture that idealizes motherhood, it’s scary to confess that, in your house, being a mother is beautiful and dirty and joyful and frustrating all at once. Admitting that it’s not easy doesn’t make you a bad mom; at least, it shouldn’t. If I can’t survive my daughter as a toddler, how the hell am I going to get through the teenage years? When Jill Smokler was first home with her small children, she thought her blog would be something to keep friends and family updated. To her surprise, she hit a chord in the hearts of mothers everywhere. I end up doing my son’s homework. It’s wrong, but so much easier. Total strangers were contributing their views on that strange reality called motherhood. As other women shared their stories, Jill realized she wasn’t alone in her feelings of exhaustion and imperfection. My eighteen month old still can’t say “Mommy” but used the word “shit” in perfect context. But she sensed her readers were still holding back, so decided to start an anonymous confessional, a place where real moms could leave their most honest thoughts without fearing condemnation. I pretend to be happy but I cry every night in the shower. The reactions were amazing: some sad, some pee-in-your-pants funny, some brutally honest. But they were real, not a commercial glamorization. I clock out of motherhood at 8 P.M. and hide in the basement with my laptop and a beer. If you’re already a fan, lock the bathroom door on your whining kids, run a bubble bath, and settle in. If you’ve not encountered Scary Mommy before, break out a glass of champagne as well, because you’ll be toasting your initiation into a select club. I know why some animals eat their young. In chapters that cover husbands (The Biggest Baby of Them All) to homework (Didn’t I Already Graduate?), Confessions of a Scary Mommy combines all-new essays from Jill with the best of the anonymous confessions. Sometimes I wish my son was still little—then I hear kids screaming at the store. As Jill says, “We like to paint motherhood as picture perfect. A newborn peacefully resting on his mother’s chest. A toddler taking tentative first steps into his mother’s loving arms. A mother fluffing her daughter’s prom dress. These moments are indeed miraculous and joyful; they can also be few and far between.” Of course you adore your kids. Of course you would lay down your life for them. But be honest now: Have you ever wondered what possessed you to sign up for the job of motherhood? STOP! DO NOT OPEN THIS BOOK UNTIL YOU RECITE THESE VOWS! I shall remember that no mother is perfect and my children will thrive because, and sometimes even in spite, of me. I shall not preach to a fellow mother who has not asked my opinion. It’s none of my damn business. I shall maintain a sense of humor about all things motherhood.

    Monique Dembele saved lives and dispensed hope in a place where childbirth is a life-and-death matter. This book tells of her unquenchable passion to better the lives of women and children in the face of poverty, unhappy marriages, and endless backbreaking work. Monique's buoyant humor and willingness to defy tradition were uniquely hers. In the course of this deeply personal narrative, as readers immerse themselves in the rhythms of West African village life, they come to know Monique as friend, mother, and inspired woman.

    When Haregwoin Teferra’s husband and daughter died within a few years of each other, her life is shattered and she becomes a recluse. But then a priest delivers an orphan to her door. The another, and another... and together they thrive.The distinguished author of Praying for Sheetrock and two-time National Book award finalist puts a human face on the AIDS crisis in Africa. When Haregwoin Teferra’s husband and 23-year-old daughter died within a few years of each other, her middle-class life in Addis Ababa, Ethiopia, was shattered. Bereft and with little to live for, Haregwoin became a recluse. Her self-imposed exile to a hut near her daughter’s grave was interrupted when a priest delivered first one, then another, orphaned teenager into her care. To everyone’s surprise, the children thrived, and so did Haregwoin. As word spread, children of all ages began to appear at her modest home: an infant brought by a dying mother, an orphaned brother and sister whose grandfather was too poor to feed them, a baby left on her doorstep. Haregwoin’s small compound became known as the rare place where ailing parents and impoverished families could safely leave their children. Soon Haregwoin was caring for sixty children, running an unofficial orphanage and day school, and learning first-hand about her country’s and her continent’s greatest challenge: the AIDS pandemic that is leaving millions of children without parents to care for them. With the flair and grace of a novelist and the reportorial instincts of a seasoned journalist, Melissa Fay Greene gets to the heart of the AIDS crisis, in a story that is nevertheless one of hope. There Is No Me Without You is the story of Haregwoin and her children: a story of struggle and despair, but also of the triumph of saved lives, and the renewed happiness of children welcomed by adoptive parents in Ethiopia, America, and around the world. Haregewoin’s remarkable story convinces us that the crisis in Africa touches every one of us in some fundamental way. At heart, this book is about children and the parents they need to care for them.

    Randy Christensen. Trained as a pediatrician, he works not in a typical hospital setting but, rather, in a 38-foot Winnebago that has been refitted as a doctor’s office on wheels. His patients are the city’s homeless adolescents and children. In the shadow of one affluent American city, Dr. Christensen has dedicated his life to caring for society's throwaway kids—the often-abused, unloved children who live on the streets without access to proper health care, all the while fending off constant threats from thugs, gangs, pimps, and other predators. With the Winnebago as his moveable medical center, Christensen and his team travel around the outskirts of Phoenix, attending to the children and teens who need him most. With tenderness and humor, Dr. Christensen chronicles everything from the struggles of the van’s early beginnings, to the support system it became for the kids, and the ultimate recognition it has achieved over the years. Along with his immense professional challenges, he also describes the trials and joys he faces while raising a growing family with his wife Amy. By turns poignant, heartbreaking, and charming, Dr. Christensen's story is a gripping and rich memoir of his work and family, one of those rare books that stays with you long after you’ve turned the last page.

    When Brooke Shields welcomed her newborn daughter, Rowan Francis, into the world, something unexpected followed--a crippling depression. Now, for the first time ever, in Down Came the Rain, Brooke talks about the trials, tribulations, and finally the triumphs that occurred before, during, and after the birth of her daughter.