Yet we face soaring worldwide rates of obesity, diabetes, high blood pressure, mental illness, heart disease, and stroke. In his fascinating new book, Dr. Lee Goldman presents a radical explanation: The key protective traits that once ensured our species' survival are now the leading global causes of illness and death. Our capacity to store food, for example, lures us into overeating, and a clotting system designed to protect us from bleeding to death now directly contributes to heart attacks and strokes. A deeply compelling narrative that puts a new spin on evolutionary biology, TOO MUCH OF A GOOD THING also provides a roadmap for getting back in sync with the modern world.

    . . a great read,"" and that has been praised as ""a delightful dance through science"" ("New York Times "bestselling author Mark Hyman, M.D.) and as a ""remarkable and insightful book [that] offers you the chance to achieve the best health of your life"" (Mark Liponis, M.D., Medical Director, Canyon Ranch).Written by bestselling author Gene Stone, "The Secrets of People Who Never Get Sick "arose from his desire to discover what might actually prevent him from getting sick himself. This book, the result of that exploration, tells the stories of twenty-five people who each possess a different secret of excellent health--a secret that makes sense and that Stone discovered has a true scientific underpinning. There are food secrets--why to take garlic and vitamin C, eat more probiotics, becomea vegan, drink a tonic of brewer's yeast. Exercise secrets--the benefits of lifting weights, the power of stretching. Environmental secrets--living in a Blue Zone, understanding the value of germs. Emotional secrets--seek out and stay in touch with friends, cultivate your spirituality. Physical secrets--nap more, take cold showers in the morning. And the wisdom that goes back generations: Yes, chicken soup works.The stories make it personal, the research makes it real, and the do-it-yourself information shows how to integrate each secret into your own life, and become the next person who never gets sick.

    On six medications and suffering constant aches, he needed to make a change. While lecturing in China, he’d heard about a remote mountainous region known as Longevity Village, a wellness Shangri-La free of heart disease, cancer, diabetes, obesity, dementia, depression, and insomnia, and where living past one hundred—in good health—is not uncommon.In the hope of understanding this incredible phenomenon, Day, a Mandarin speaker, decided to spend some time living in Longevity Village. He learned everything he could about this place and its people, and met its centenarians. His research revealed seven principles that work in tandem to create health, happiness, and longevity—rules he applied to his own life. Six months later, he’d lost thirty pounds, dropped one hundred points off his cholesterol and twenty-five points off his blood pressure, and was even cured of his acid reflux and insomnia. In 2014 he began a series of four-month support groups comprised of patients who worked together to apply the lessons of Longevity Village to their lives. Ninety-two percent of the participants were able to adhere to their plans and stay on pace to reach their health goals.

    The chapters introduce each of the main neurotransmitters involved with behavior, discuss its role in the brain, present some background on how it is generally turned on and off, and explain ways to influence it through what we consume.

    Psychiatrist and psychoanalyst, Norman Doidge, M.D., traveled the country to meet both the brilliant scientists championing neuroplasticity and the people whose lives they’ve transformed - people whose mental limitations or brain damage were seen as unalterable. We see a woman born with half a brain that rewired itself to work as a whole, blind people who learn to see, learning disorders cured, IQs raised, aging brains rejuvenated, stroke patients learning to speak, children with cerebral palsy learning to move with more grace, depression and anxiety disorders successfully treated, and lifelong character traits changed. Using these marvelous stories to probe mysteries of the body, emotion, love, sex, culture, and education, Dr. Doidge has written an immensely moving, inspiring book that will permanently alter the way we look at our brains, human nature, and human potential.

    Researchers are delving into the mysteries of stem cells and the human genome, discovering what it means to grow old and how to keep those processes from happening. This isn't science fiction; it's real, it's serious, and it's on track to revolutionize our definitions of life and mortality.In Immortality, Inc., veteran science journalist Chip Walter gains exclusive access to the champions of this radical cause, delivering a book that brings together for the first time the visions of molecular biologist and Apple chairman Arthur Levinson, genomics entrepreneur Craig Venter, futurist Ray Kurzweil, rejuvenation trailblazer Aubrey de Grey, and stem cell expert Robert Hariri. Along the way, Walter weaves in fascinating conversations about life, death, aging, and the future of the human race.

    It could be an oddball researcher’s genius insight, a catalyzing moment in geopolitical history, a new breakthrough technology, or an unexpected but welcome side effect discovered during clinical trials. Piece together these stories, as Thomas Hager does in this remarkable, century-spanning history, and you can trace the evolution of our culture and the practice of medicine.  ​Beginning with opium, the “joy plant,” which has been used for 10,000 years, Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.

    Full of the latest research and ground-breaking evidence, packed with useful advice, this book really could save your life.

    The microbiota interacts with our bodies in a number of powerful ways; the Sonnenburgs argue that it determines in no small part whether we’re sick or healthy, fit or obese, sunny or moody. The microbiota has always been with us, and in fact has coevolved with humans, entwining its functions with ours so deeply, the Sonnenburgs show us, humans are really composite organisms having both microbial and human parts. But now, they argue, because of changes to diet, antibiotic over-use, and over-sterilization, our gut microbiota is facing a “mass extinction event,” which is causing our bodies to go haywire, and may be behind the mysterious spike in some of our most troubling modern afflictions, from food allergies to autism, cancer to depression. It doesn’t have to be this way.The Good Gut offers a new plan for health that focuses on how to nourish your microbiota, including recipes and a menu plan. In this groundbreaking work, the Sonnenburgs show how we can keep our microbiota off the endangered species list and how we can strengthen the community that inhabits our gut and thereby improve our own health. The answer is unique for each of us, and it changes as you age. In this important and timely investigation, the Sonnenburgs look at safe alternatives to antibiotics; dietary and lifestyle choices to encourage microbial health; the management of the aging microbiota; and the nourishment of your own individual microbiome. Caring for our gut microbes may be the most important health choice we can make.

    Despite advice from experts, governments and dieticians about the dangers of too much fat, sugar, protein and lack of exercise, our nutrition - and the global obesity crisis - is getting worse. Why can one person eat a certain meal and gain weight and another eat exactly the same food and lose pounds? Genes provide part of the answer, but we have been overlooking one vital aspect of diet that lies within us. Thanks to recent breakthroughs, scientists have begun to examine the permanent residents in our guts: the thousands of previously unknown but essential microbes whose job it is to digest our food and keep us alive. Drawing on the latest science and his own research team's pioneering work, Professor Tim Spector explores the hidden world of the microbiome and demystifies the common misconceptions about fat, calories, vitamins and nutrients. Only by understanding how our own microbes interact with our bodies can we overcome our confusion about modern diets and nutrition to regain the correct balance of our ancestors.Mixing cutting-edge discoveries, illuminating science and his own case studies, Spector shows why we should stop listening to the myths of diet fads and instead embrace diversity for a healthy gut and a healthy body.

    It touches on its evolutionary development, its algorithmic nature and its scientific history by bridging ideas across Neuroscience, Computer Science, Biotechnology, Evolutionary History, Cognitive Science, Political Philosophy, and Artificial Intelligence.Never before had there been nearly as many scientists, resources or productive research focused on these topics, and humanity has achieved some understanding and some clarification. With the speed of progress it is timely to communicate an overreaching perspective, this book puts an emphasis on conveying the essential questions and what we know about their answers in a simple, clear and exciting way.Humans, along with the first RNA molecules, the first life forms, the first brains, the first conscious animals, the first societies and the first artificial agents constitute an amazing and crucial development in a path of increasingly complex computational intelligence. And yet, we occupy a minuscule time period in the history of Earth, a history that has been written by Genes, by Cultures and by Consciousnesses. If we abandon our anthropomorphic bias it becomes obvious that Humans are not so special after all. We are an important but short and transitory step among many others in a bigger story. The story of our computational minds, which is ours but not only ours. What is the relationship between computation, cognition and everything else? What is life and how did it originate? What is the role of culture in human minds? What do we know about the algorithmic nature of the mind, can we engineer it? What is the computational explanation of consciousness? What are some possible future steps in the evolution of minds? The underlying thread is the computational nature of the Mind which results from the mixture of Genes, Cultures and Consciousness. While these three interact in complex ways, they are ultimately computational systems on their own which appeared at different stages of history and which follow their own selective processes operating at different time scales. As technology progresses, the distinction between the three components materializes and will be a key determinant of the future.Among the many topics covered are the origin of life, the concept of computation and its relation to Turing Machines, cultural evolution and the notion of a Selfish Meme, free will and determinism, moral relativity, the hard problem of consciousness, the different theories of concepts from the perspective of cognitive science, the current status of AI and Machine Learning including the symbolic vs sub-symbolic dichotomy, the contrast between logical reasoning and neural networks, and the recent history of Deep Learning, Geoffrey Hinton, DeepMind and its algorithm AlphaGo. It also develops on the history of science and looks into the possible future building on the work of authors like Daniel Dennett, Yuval Harari, Richard Dawkins, Francis Crick, George Church, David Chalmers, Susan Carey, Stanislas Dehaene, Robert Boyd, Joseph Henrich, Daniel Kahneman, Moran Cerf, Josh Tenenbaum, David Deutsch, Steven Pinker, Ray Kurzweil, John von Neumann, Herbert Simon and many more. Andres Campero is a researcher and PhD student at the Brain and Cognitive Sciences Department and at the Computer Science and Artificial Intelligence Laboratory at the Massachusetts Institute of Technology (MIT).

    Life remains the only way to make life. Are we still missing a vital ingredient in its creation?      Like Richard Dawkins' The Selfish Gene, which provided a new perspective on how evolution works, Life on the Edge alters our understanding of our world's fundamental dynamics. Bringing together first-hand experience at the cutting edge of science with unparalleled gifts of explanation, Jim Al-Khalili and Johnjoe Macfadden reveal that missing ingredient to be quantum mechanics; the phenomena that lie at the heart of this most mysterious of sciences. Drawing on recent ground-breaking experiments around the world, each chapter in Life on the Edge engages by illustrating one of life's puzzles: How do migrating birds know where to go? How do we really smell the scent of a rose? How do our genes copy themselves with such precision? Life on the Edge accessibly reveals how quantum mechanics can answer these probing questions of the universe. Guiding the reader through the rapidly unfolding discoveries of the last few years, Al-Khalili and McFadden communicate the excitement of the explosive new field of quantum biology and its potentially revolutionary applications, while offering insights into the biggest puzzle of all: what is life? As they brilliantly demonstrate in these groundbreaking pages, life exists on the quantum edge.

    In The Compatibility Gene, one of our foremost immunologists tells the remarkable history of these genes' discovery and the unlocking of their secrets. Davis shows how the compatibility gene is radically transforming our knowledge of the way our bodies work - and is having profound consequences for medical research and ethics. Looking to the future, he considers the startling possibilities of what these wondrous discoveries might mean for you and me.

    Ratey, MD.Did you know you can beat stress, lift your mood, fight memory loss, sharpen your intellect, and function better than ever simply by elevating your heart rate and breaking a sweat? The evidence is incontrovertible: Aerobic exercise physically remodels our brains for peak performance. In SPARK, John J. Ratey, M.D., embarks upon a fascinating and entertaining journey through the mind-body connection, presenting startling research to prove that exercise is truly our best defense against everything from depression to ADD to addiction to aggression to menopause to Alzheimer's. Filled with amazing case studies (such as the revolutionary fitness program in Naperville, Illinois, which has put this school district of 19,000 kids first in the world of science test scores), SPARK is the first book to explore comprehensively the connection between exercise and the brain. It will change forever the way you think about your morning run---or, for that matter, simply the way you think

    A lyrical journey from hope to despair and back again, The First Cell explores cancer from every angle: medical, scientific, cultural, and personal. Indeed, Raza describes how she bore the terrible burden of being her own husband's oncologist as he succumbed to leukemia. Like When Breath Becomes Air, The First Cell is no ordinary book of medicine, but a book of wisdom and grace by an author who has devoted her life to making the unbearable easier to bear.