By 1988 she was living at home but was brain dead after a tragic cycle of misunderstanding, over-medication, and culture clash: "What the doctors viewed as clinical efficiency the Hmong viewed as frosty arrogance." The Spirit Catches You and You Fall Down is a tragedy of Shakespearean dimensions, written with the deepest of human feeling. Sherwin Nuland said of the account, "There are no villains in Fadiman's tale, just as there are no heroes. People are presented as she saw them, in their humility and their frailty—and their nobility.

    There is Edward Oxford, who shot at Queen Victoria, and Richard Dadd, the brilliant artist and murderer of his father. There is also William Chester Minor, the surgeon from America who killed a stranger in London, and then played a key part in creating the world's finest dictionary. Finally, there is Christiana Edmunds, ‘The Chocolate Cream Poisoner’ and frustrated lover.To these four tales are added new ones, previously unknown. There were five women who went on to become mothers in Broadmoor, giving birth to life when three of them had previously taken it. Then there were the numerous escapes, actual and attempted, as the first doctors tried to assert control over their residents.These are stories from the edge of where true crime meets mental illness. Broadmoor Revealed recounts what life was like for the criminally insane, over one hundred years ago.

    That all changed in less than a generation with the discovery and development of a new category of medicine known as antibiotics. By 1955, the age-old evolutionary relationship between humans and microbes had been transformed, trivializing once-deadly infections. William Rosen captures this revolution with all its false starts, lucky surprises, and eccentric characters. He explains why, given the complex nature of bacteria—and their ability to rapidly evolve into new forms—the only way to locate and test potential antibiotic strains is by large-scale, systematic, trial-and-error experimentation. Organizing that research needs large, well-funded organizations and businesses, and so our entire scientific-industrial complex, built around the pharmaceutical company, was born. Timely, engrossing, and eye-opening, Miracle Cure is a must-read science narrative—a drama of enormous range, combining science, technology, politics, and economics to illuminate the reasons behind one of the most dramatic changes in humanity’s relationship with nature since the invention of agriculture ten thousand years ago.

    Formerly handed down under oath of secrecy, this clear, concise handbook discusses: the fundamental principles of alchemy; directions for the formation of an inexpensive home laboratory, with illustrations of the necessary equipment; stepbystep instructions for the work of the Lesser Circulation, the alchemical transformation within the plant kingdomthe necessary prerequisite for any work in the mineral kingdom.

    In this exciting book, we meet a who's who of heartless murderers. Mary Ann Cotton, who used arsenic to murder her mother, three husbands, a lover, eight of her own children, and seven step children; Michael Swango, who may have killed as many as 60 of his patients and several of his colleagues during the 20 years he practiced as a doctor and paramedic; and even Saddam Hussein, who used thallium sulfate to poison his political rivals. Emsley also shows which toxic elements may have been behind the madness of King George III, the delusions of Isaac Newton, and the strange death of King Charles II. In addition, the book examines many modern day environmental catastrophes, including accidental mass poisonings from lead and arsenic, and the Minamata Bay disaster in Japan. Written by a leading science writer, famous for his knowledge of the elements and their curious and colorful histories, The Elements of Murder offers an enticing combination of true crime tales and curious science that adds up to an addictive read.

    Improper use of antibiotics. Local warfare. Massive refugee migration. Changing social and environmental conditions around the world have fostered the spread of new and potentially devastating viruses and diseases—HIV, Lassa, Ebola, and others. Laurie Garrett takes you on a fifty-year journey through the world's battles with microbes and examines the worldwide conditions that have culminated in recurrent outbreaks of newly discovered diseases, epidemics of diseases migrating to new areas, and mutated old diseases that are no longer curable. She argues that it is not too late to take action to prevent the further onslaught of viruses and microbes, and offers possible solutions for a healthier future.

    At the dawn of the sixteenth century, Europe was emerging from an age of ignorance and uncertainty. New lands were being discovered and old ones revitalized. People abandoned the ideals of medieval times to make startling advances in technology, science, and art. Here, award-winning historian Lacey Baldwin Smith vividly brings to life the story of Queen Elizabeth - perhaps the most influential sovereign in England's history - and the age she created. During her reign, Queen Elizabeth, last of the Tudor monarchs, presided over developments that still shape and inform our lives and culture today, including her patronage of William Shakespeare, the formation of the Church of England, victory over the Spanish Armada, even the execution of Mary Queen of Scots. Smith's keen eye for detail and sense of how those details have echoed through the centuries make this book essential reading for anyone who wants to understand how history works.

    It covers history from prehistoric times to the present; the flora of the river; paintings and photographs inspired by the Thames; its geology, smells and colour; its literature, laws and landscapes; its magic and myths; its architecture, trade and weather.This book meanders gloriously, rather as the river does itself: here are Toad of Toad Hall and Julius Caesar, Henry VIII and Shelley, Turner and Three Men in a Boat. The reader learns about the fishes that swam in the river and the boats that plied on its surface; about floods and tides; hauntings and suicides; sewers, miasmas and malaria; locks, weirs and embankments; bridges, docks and palaces. All the towns and villages along the river's 215-mile length are described.Peter Ackroyd has a genius for digging out the most surprising and entertaining details, and for writing about them in the most magisterial prose.

    Drawing on the diaries of a midwife and healer in eighteenth-century Maine, this intimate history illuminates the medical practices, household economies, religious rivalries, and sexual mores of the New England frontier.

    Dr. Manheimer describes the plights of twelve very different patients--from dignitaries at the nearby UN, to supermax prisoners at Riker's Island, to illegal immigrants, and Wall Street tycoons.Manheimer was not only the medical director of the country's oldest public hospital for over 13 years, but he was also a patient. As the book unfolds, the narrator is diagnosed with cancer, and he is forced to wrestle with the end of his own life even as he struggles to save the lives of others.

    Israel Regarclie's brilliant and beautiful compilation of many of Crowtey's best magical writings from the rare and expensive eleven number Equinox. Regardie's original Introduction has been posthumously edited and updated for this new edition.

    Fearful that plutonium  might cause a cancer epidemic among workers and desperate to learn more about what it could do to the human body, the Manhattan Project's medical doctors embarked upon an experiment in which eighteen unsuspecting patients in  hospital wards throughout the country were secretly injected with the cancer-causing substance. Most of these patients would go to their graves without ever knowing what had been done to them.Now, in The Plutonium Files, Pulitzer Prize-winning reporter Eileen Welsome reveals for the first time the breadth of the extraordinary fifty-year cover-up surrounding the plutonium injections, as well as the deceitful nature of thousands of other experiments conducted on American citizens in the postwar years. Welsome's remarkable investigation spans the 1930s to the 1990s and draws upon hundreds of newly declassified documents and other primary sources to disclose this shadowy chapter in American history. She gives a voice to such innocents as Helen Hutchison, a young woman who entered a prenatal clinic in Nashville for a routine checkup and was instead given a radioactive "cocktail" to drink; Gordon Shattuck, one of several boys at a state school for the developmentally disabled in Massachusetts who was fed radioactive oatmeal for breakfast; and Maude Jacobs, a Cincinnati woman suffering from cancer and subjected to an experimental radiation treatment designed to help military planners learn how to win a nuclear war. Welsome also tells the stories of the scientists themselves, many of whom learned the ways of secrecy on the Manhattan Project. Among them are Stafford Warren, a grand figure whose bravado masked a cunning intelligence; Joseph Hamilton, who felt he was immune to the dangers of radiation only to suffer later from a fatal leukemia; and physician Louis Hempelmann, one of the most enthusiastic supporters of the plan to inject humans with potentially carcinogenic doses of plutonium. Hidden discussions of fifty years past are reconstructed here, wherein trusted government officials debated the ethical and legal implications of the experiments, demolishing forever the argument that these studies took place in a less enlightened era. Powered by her groundbreaking reportage and singular narrative gifts, Eileen Welsome has created a work of profound humanity as well as major historical significance.From the Hardcover edition.

    It is essentially a death sentence. The only accepted form of treatment - starvation - whittles her down to forty-five pounds skin and bones. Miles away, Canadian researchers Frederick Banting and Charles Best manage to identify and purify insulin from animal pancreases - a miracle soon marred by scientific jealousy, intense business competition and fistfights. In a race against time and a ravaging disease, Elizabeth becomes one of the first diabetics to receive insulin injections - all while its discoverers and a little known pharmaceutical company struggle to make it available to the rest of the world.Relive the heartwarming true story of the discovery of insulin as it's never been told before. Written with authentic detail and suspense, and featuring walk-ons by William Howard Taft, Woodrow Wilson, and Eli Lilly himself, among many others.

    By demystifying the fantasies surrounding cancer, Sontag shows cancer for what it is - just a disease. Cancer, she argues, is not a curse, not a punishment, certainly not an embarrassment and, it is highly curable, if good treatment is followed. Almost a decade later, with the outbreak of a new, stigmatized disease replete with mystifications and punitive metaphors, Sontag wrote a sequel to Illness as Metaphor, extending the argument of the earlier book to the AIDS pandemic.These two essays now published together, Illness as Metaphor and AIDS and Its Metaphors, have been translated into many languages and continue to have an enormous influence on the thinking of medical professionals and, above all, on the lives of many thousands of patients and caregivers.

    In July 1518 a terrifying and mysterious plague struck the medieval city of Strasbourg. Hundreds of men and women danced wildly, day after day, in the punishing summer heat. They did not want to dance, but could not stop. Throughout August and early September more and more were seized by the same terrible compulsion. By the time the epidemic subsided, heat and exhaustion had claimed an untold number of lives, leaving thousands bewildered and bereaved, and an enduring enigma for future generations. Drawing on fresh evidence, John Waller's account of the bizarre events of 1518 explains why Strasbourg's dancing plague took place. In doing so it leads us into a largely vanished world, evoking the sights, sounds, aromas, diseases and hardships, the fervent supernaturalism, and the desperate hedonism of the late medieval world. At the same time, the extraordinary story this book tells offers rich insights into how people behave when driven beyond the limits of endurance. Above all, this is an exploration into the strangest capabilities of the human mind and the extremes to which fear and irrationality can lead us.