Ironically, the "discovery" was really no discovery at all: Ether and nitrous oxide had been known for more than forty years to cause insensitivity to pain, yet, with names like "laughing gas," they were used almost solely for entertainment. Meanwhile, patients still underwent operations during which they saw, heard, and felt every cut the surgeon made. The image of a grim and grisly operating room, like the one in Mary Shelley's Frankenstein, was in fact starkly accurate in portraying the conditions of surgery before anesthesia.With hope for relief seemingly long gone, the breakthrough finally came about by means of a combination of coincidence and character, as a cunning Boston dentist crossed paths with an inventive colleague from Hartford and a brilliant Harvard-trained physician. William Morton, Horace Wells, and Charles Jackson: a con man, a dreamer, and an intellectual. Though Wells was crushed by derision when he tried to introduce anesthetics, Morton prevailed, with help from Jackson. The result was Ether Day, October 16, 1846, celebrated around the world. By that point, though, no honor was enough. Ether Day was not only the dawn of modern surgery, but the beginning of commercialized medicine as well, as Morton patented the discovery.What followed was a battle so bitter that it sent all three men spiraling wildly out of control, at the same time that anesthetics began saving countless lives. Meticulously researched and masterfully written, Ether Day is a riveting look at one of history's most remarkable untold stories.

    David Agus tackles these fundamental questions and dismantles misperceptions about what “health” really means. Presenting an eye-opening picture of the human body and all the ways it works—and fails—Dr. Agus shows us how a new perspective on our individual health will allow us to achieve a long, vigorous life. Offering insights and access to powerful new technologies that promise to transform medicine, Dr. Agus emphasizes his belief that there is no “right” answer, no master guide that is “one size fits all.” Each one of us must get to know our bodies in uniquely personal ways, and he shows us exactly how to do that. A bold call for all of us to become our own personal health advocates, The End of Illness is a moving departure from orthodox thinking.

    He was sleek and prosperous, with a dainty goatee. Though he smiled reassuringly, the poet noticed that he kept a safe distance. In a soothing, urbane voice, the physician explained the treatment: stewed prunes to evacuate the bowels; succulent meats to ease digestion; cinnabar and the sweating tub to cleanse the disease from the skin. The doctor warned of minor side effects: uncontrolled drooling, fetid breath, bloody gums, shakes and palsies. Yet desperate diseases called for desperate remedies, of course.Were Shakespeare's shaky handwriting, his obsession with venereal disease, and his premature retirement connected? Did John Milton go blind from his propaganda work for the Puritan dictator Oliver Cromwell, as he believed, or did he have a rare and devastating complication of a very common eye problem? Did Jonathan Swift's preoccupation with sex and filth result from a neurological condition that might also explain his late-life surge in creativity? What Victorian plague wiped out the entire Brontë family? What was the cause of Nathaniel Hawthorne's sudden demise? Were Herman Melville's disabling attacks of eye and back pain the product of "nervous affections," as his family and physicians believed, or did he actually have a malady that was unknown to medical science until well after his death? Was Jack London a suicide, or was his death the product of a series of self-induced medical misadventures? Why did W. B. Yeats's doctors dose him with toxic amounts of arsenic? Did James Joyce need several horrific eye operations because of a strange autoimmune disease acquired from a Dublin streetwalker? Did writing Nineteen Eighty-Four actually kill George Orwell? The Bard meets House, M.D. in this fascinating untold story of the impact of disease on the lives and works of some the finest writers in the English language. In Shakespeare's Tremor and Orwell's Cough, John Ross cheerfully debunks old biographical myths and suggests fresh diagnoses for these writers' real-life medical mysteries. The author takes us way back, when leeches were used for bleeding and cupping was a common method of cure, to a time before vaccinations, sterilized scalpels, or real drug regimens. With a healthy dose of gross descriptions and a deep love for the literary output of these ten greats, Ross is the doctor these writers should have had in their time of need.

    Readers of "The New Yorker" may be familiar with the author's suspenseful tales of strange illnesses, rare diseases, poisons and parasites.

    A natural overachiever, Collins' success, in college and medical school led to a surgical residency at one of the most respected medical centers in the world, the famed Mayo Clinic. But compared to his fellow residents Collins feels inadequate and unprepared. All too soon, the euphoria of beginning his career as an orthopedic resident gives way to the feeling he is a counterfeit, an imposter who has infiltrated a society of brilliant surgeons.This story of Collins' four-year surgical residency traces his rise from an eager but clueless first-year resident to accomplished Chief Resident in his final year. With unparalleled humor, he recounts the disparity between people's perceptions of a doctor's glamorous life and the real thing: a succession of run down cars that are towed to the junk yard, long weekends moonlighting at rural hospitals, a family that grows larger every year, and a laughable income.Collins' good nature helps him over some of the rough spots but cannot spare him the harsh reality of a doctor's life. Every day he is confronted with decisions that will change people's lives-or end them-forever. A young boy's leg is mangled by a tractor: risk the boy's life to save his leg, or amputate immediately? A woman diagnosed with bone cancer injures her hip: go through a painful hip operation even though she has only months to live? Like a jolt to the system, he is faced with the reality of suffering and death as he struggles to reconcile his idealism and aspiration to heal with the recognition of his own limitations and imperfections.Unflinching and deeply engaging, Hot Lights, Cold Steel is a humane and passionate reminder that doctors are people too. This is a gripping memoir, at times devastating, others triumphant, but always compulsively readable.

    When death is sudden or unexplained, it falls to Shepherd to establish the cause. Each post-mortem is a detective story in its own right - and Shepherd has performed over 23,000 of them. Through his skill, dedication and insight, Dr Shepherd solves the puzzle to answer our most pressing question: how did this person die?From serial killer to natural disaster, 'perfect murder' to freak accident, Shepherd takes nothing for granted in pursuit of truth. And while he's been involved in some of the most high-profile cases of recent times, it's often the less well known encounters that prove the most perplexing, intriguing and even bizarre. In or out of the public eye, his evidence has put killers behind bars, freed the innocent and turned open-and-shut cases on their heads.But a life in death, bearing witness to some of humanity's darkest corners, exacts a price and Shepherd doesn't flinch from counting the cost to him and his family.

    And unlike dogs, cats offer humans no practical benefit. The truth is they are sadly incompetent mouse-catchers and now pose a threat to many ecosystems. Yet, we love them still.Content:Catacombs Cat's cradle What's the catch? The cats that ate the canaries The cat lobby CAT scan Pandora's litter box Lions and toygers and lykoi Nine likes.

    Award-winning author Jonathan Edlow, M.D., shows the doctor as detective and the epidemiologist as elite sleuth in stories that are as gripping as the best thrillers.In these stories a notorious stomach bug turns a suburban dinner party into a disaster that almost claims its host; a diminutive woman routinely eats more than her football-playing boyfriend but continually loses weight; a young executive is diagnosed with lung cancer, yet the tumors seem to wax and wane inexplicably. Written for the lay person who wishes to better grasp how doctors decipher the myriad clues and puzzling symptoms they often encounter, each story presents a very different case where doctors must work to find the accurate diagnosis before it is too late. Edlow uses his unique ability to relate complex medical concepts in a writing style that is clear, engaging and easily understandable. The resulting stories both entertain us and teach us much about medicine, its history and the subtle interactions among pathogens, humans, and the environment.

    Exploring the history of cannibalism, the neurology of people who are sexually attracted to animals, the evolution of human body fluids, the science of homosexuality, and serious questions about life and death, Bering astutely covers a generous expanse of our kaleidoscope of quirks and origins.With his characteristic irreverence and trademark cheekiness, Bering leaves no topic unturned or curiosity unexamined, and he does it all with an audaciously original voice. Whether you're interested in the psychological history behind the many facets of sexual desire or the evolutionary patterns that have dictated our current mystique and phallic physique, Why Is the Penis Shaped Like That? is bound to create lively discussion and debate for years to come.

    From New England aquarium tanks to the reefs of French Polynesia and the Gulf of Mexico, she has befriended octopuses with strikingly different personalities—gentle Athena, assertive Octavia, curious Kali, and joyful Karma. Each creature shows her cleverness in myriad ways: escaping enclosures like an orangutan; jetting water to bounce balls; and endlessly tricking companions with multiple “sleights of hand” to get food.Scientists have only recently accepted the intelligence of dogs, birds, and chimpanzees but now are watching octopuses solve problems and are trying to decipher the meaning of the animal’s color-changing techniques. With her “joyful passion for these intelligent and fascinating creatures” (Library Journal Editors’ Spring Pick), Montgomery chronicles the growing appreciation of this mollusk as she tells a unique love story. By turns funny, entertaining, touching, and profound, The Soul of an Octopus reveals what octopuses can teach us about the meeting of two very different minds.

    If America could send a man to the moon, shouldn’t the best surgeons in the world be able to build an artificial heart? In Ticker, Texas Monthly executive editor and two time National Magazine Award winner Mimi Swartz shows just how complex and difficult it can be to replicate one of nature’s greatest creations. Part investigative journalism, part medical mystery, Ticker is a dazzling story of modern innovation, recounting fifty years of false starts, abysmal failures and miraculous triumphs, as experienced by one the world’s foremost heart surgeons, O.H. “Bud” Frazier, who has given his life to saving the un-savable. His journey takes him from a small town in west Texas to one of the country’s most prestigious medical institutions, The Texas Heart Institute, from the halls of Congress to the animal laboratories where calves are fitted with new heart designs. The roadblocks to success —medical setbacks, technological shortcomings, government regulations – are immense. Still, Bud and his associates persist, finding inspiration in the unlikeliest of places. A field beside the Nile irrigated by an Archimedes screw. A hardware store in Brisbane, Australia. A seedy bar on the wrong side of Houston. Until post WWII, heart surgery did not exist. Ticker provides a riveting history of the pioneers who gave their all to the courageous process of cutting into the only organ humans cannot live without. Heart surgeons Michael DeBakey and Denton Cooley, whose feud dominated the dramatic beginnings of heart surgery. Christian Barnaard, who changed the world overnight by performing the first heart transplant. Inventor Robert Jarvik, whose artificial heart made patient Barney Clark a worldwide symbol of both the brilliant promise of technology and the devastating evils of experimentation run amuck. Rich in supporting players, Ticker introduces us to Bud’s brilliant colleagues in his quixotic quest to develop an artificial heart: Billy Cohn, the heart surgeon and inventor who devotes his spare time to the pursuit of magic and music; Daniel Timms, the Brisbane biomedical engineer whose design of a lightweight, pulseless heart with but a single moving part offers a new way forward. And, as government money dries up, the unlikeliest of backers, Houston’s furniture king, Mattress Mack. In a sweeping narrative of one man’s obsession, Swartz raises some of the hardest questions of the human condition. What are the tradeoffs of medical progress? What is the cost, in suffering and resources, of offering patients a few more months, or years of life? Must science do harm to do good? Ticker takes us on an unforgettable journey into the power and mystery of the human heart.

    But getting here has not been a simple story of selfless men working tirelessly in the pursuit of medical advancement. Instead it's a bloodstained tale of blunders, arrogance, mishap and murder. In trying to keep us alive, surgeons have all too often killed us off, and life-saving solutions have often come from the most surprising places. Accompanying a major BBC series, "Blood and Guts" is an incredible story of stolen corpses, medical fraud, lobotomized patients - and every now and then courageous advances that have saved the lives of millions around the world. You may think twice before going under the knife.

      In 1875, tuberculosis was the deadliest disease in the world, accountable for a third of all deaths. A diagnosis of TB—often called consumption—was a death sentence. Then, in a triumph of medical science, a German doctor named Robert Koch deployed an unprecedented scientific rigor to discover the bacteria that caused TB. Koch soon embarked on a remedy—a remedy that would be his undoing.   When Koch announced his cure for consumption, Arthur Conan Doyle, then a small-town doctor in England and sometime writer, went to Berlin to cover the event. Touring the ward of reportedly cured patients, he was horrified. Koch’s "remedy" was either sloppy science or outright fraud.   But to a world desperate for relief, Koch’s remedy wasn’t so easily dismissed. As Europe’s consumptives descended upon Berlin, Koch urgently tried to prove his case. Conan Doyle, meanwhile, returned to England determined to abandon medicine in favor of writing. In particular, he turned to a character inspired by the very scientific methods that Koch had formulated: Sherlock Holmes.   Capturing the moment when mystery and magic began to yield to science, The Remedy chronicles the stunning story of how the germ theory of disease became a true fact, how two men of ambition were emboldened to reach for something more, and how scientific discoveries evolve into social truths.

    Armed with a healthy dose of wit and curiosity, medical journalist Randi Hutter Epstein reveals the “invigorating history” (Nature) of hormones and the age-old quest to control them through the back rooms, basements, and labs where endocrinology began.

    She finds that you cannot immunize your child, or yourself, from the world.In this bold, fascinating book, Biss investigates the metaphors and myths surrounding our conception of immunity and its implications for the individual and the social body. As she hears more and more fears about vaccines, Biss researches what they mean for her own child, her immediate community, America, and the world, both historically and in the present moment. She extends a conversation with other mothers to meditations on Voltaire's Candide, Bram Stoker's Dracula, Rachel Carson's Silent Spring, Susan Sontag's AIDS and Its Metaphors, and beyond.On Immunity is a moving account of how we are all interconnected-our bodies and our fates.