She finds that you cannot immunize your child, or yourself, from the world.In this bold, fascinating book, Biss investigates the metaphors and myths surrounding our conception of immunity and its implications for the individual and the social body. As she hears more and more fears about vaccines, Biss researches what they mean for her own child, her immediate community, America, and the world, both historically and in the present moment. She extends a conversation with other mothers to meditations on Voltaire's Candide, Bram Stoker's Dracula, Rachel Carson's Silent Spring, Susan Sontag's AIDS and Its Metaphors, and beyond.On Immunity is a moving account of how we are all interconnected-our bodies and our fates.

    Now it could be the key to healing millions with genetic diseases of every type—from Alzheimer's and Parkinson's to diabetes and sickle cell anemia.In 1974, Joey O'Donnell was born with strange symptoms. His insatiable appetite, incessant vomiting, and a relentless cough—which shook his tiny, fragile body and made it difficult to draw breath—confounded doctors and caused his parents agonizing, sleepless nights. After six sickly months, his salty skin provided the critical clue: he was one of thousands of Americans with cystic fibrosis, an inherited lung disorder that would most likely kill him before his first birthday.The gene and mutation responsible for CF were found in 1989—discoveries that promised to lead to a cure for kids like Joey. But treatments unexpectedly failed and CF was deemed incurable. It was only after the Cystic Fibrosis Foundation, a grassroots organization founded by parents, formed an unprecedented partnership with a fledgling biotech company that transformative leaps in drug development were harnessed to produce groundbreaking new treatments: pills that could fix the crippled protein at the root of this deadly disease.From science writer Bijal P. Trivedi, Breath from Salt chronicles the riveting saga of cystic fibrosis, from its ancient origins to its identification in the dank autopsy room of a hospital basement, and from the CF gene's celebrated status as one of the first human disease genes ever discovered to the groundbreaking targeted genetic therapies that now promise to cure it.Told from the perspectives of the patients, families, physicians, scientists, and philanthropists fighting on the front lines, Breath from Salt is a remarkable story of unlikely scientific and medical firsts, of setbacks and successes, and of people who refused to give up hope—and a fascinating peek into the future of genetics and medicine.

    With the verve of a novelist, Chris Matthews gives us just that. We see this most beloved president in the company of friends. We see and feel him close-up, having fun and giving off that restlessness of his. We watch him navigate his life from privileged, rebellious youth to gutsy American president. We witness his bravery in war and selfless rescue of his PT boat crew. We watch JFK as a young politician learning to play hardball and watch him grow into the leader who averts a nuclear war.What was he like, this person whose own wife called him “that elusive, unforgettable man”? The Jack Kennedy you discover here wanted never to be alone, never to be bored. He loved courage, hated war, lived each day as if it were his last.Chris Matthews’s extraordinary biography is based on personal interviews with those closest to JFK, oral histories by top political aide Kenneth O’Donnell and others, documents from his years as a student at Choate, and notes from Jacqueline Kennedy’s first interview after Dallas. You’ll learn the origins of his inaugural call to “Ask what you can do for your country.” You’ll discover his role in the genesis of the Peace Corps, his stand on civil rights, his push to put a man on the moon, his ban on nuclear arms testing. You’ll get, more than ever before, to the root of the man, including the unsettling aspects of his personal life. As Matthews writes, “I found a fighting prince never free of pain, never far from trouble, never accepting the world he found, never wanting to be his father’s son. He was a far greater hero than he ever wished us to know.”

    Working in the kitchens of the upper class, she left a trail of disease in her wake, until one enterprising and ruthless “medical engineer” proposed the inconceivable notion of the “asymptomatic carrier”—and from then on Mary Mallon was a hunted woman. In order to keep New York’s citizens safe from Mallon, the Department of Health sent her to North Brother Island where she was kept in isolation from 1907-1910. She was released under the condition that she never work as a cook again. Yet for Mary—spoiled by her status and income and genuinely passionate about cooking—most domestic and factory jobs were heinous. She defied the edict.Bringing early twentieth-century New York alive—the neighborhoods, the bars, the park being carved out of upper Manhattan, the emerging skyscrapers, the boat traffic—Fever is as fiercely compelling as Typhoid Mary herself, an ambitious retelling of a forgotten life. In the hands of Mary Beth Keane, Mary Mallon becomes an extraordinarily dramatic, vexing, sympathetic, uncompromising, and unforgettable character.

    He boarded a friend’s yacht, sailed into the calm blue waters of Long Island Sound, and--poof!--disappeared. He would not be heard from again for five days. What happened during those five days, and in the days and weeks that followed, was so incredible that, even when the truth was finally revealed, many Americans simply would not believe it.The President Is a Sick Man details an extraordinary but almost unknown chapter in American history: Grover Cleveland’s secret cancer surgery and the brazen political cover-up by a politician whose most memorable quote was “Tell the truth.” When an enterprising reporter named E. J. Edwards exposed the secret operation, Cleveland denied it. The public believed the “Honest President,” and Edwards was dismissed as “a disgrace to journalism.” The facts concerning the disappearance of Grover Cleveland that summer were so well concealed that even more than a century later a full and fair account has never been published. Until now.

    With all our media now traveling a single network, an unprecedented potential is building for centralized control over what Americans see and hear. Could history repeat itself with the next industrial consolidation? Could the Internet—the entire flow of American information—come to be ruled by one corporate leviathan in possession of “the master switch”? That is the big question of Tim Wu’s pathbreaking book.As Wu’s sweeping history shows, each of the new media of the twentieth century—radio, telephone, television, and film—was born free and open. Each invited unrestricted use and enterprising experiment until some would-be mogul battled his way to total domination. Here are stories of an uncommon will to power, the power over information: Adolph Zukor, who took a technology once used as commonly as YouTube is today and made it the exclusive prerogative of a kingdom called Hollywood . . . NBC’s founder, David Sarnoff, who, to save his broadcast empire from disruptive visionaries, bullied one inventor (of electronic television) into alcoholic despair and another (this one of FM radio, and his boyhood friend) into suicide . . . And foremost, Theodore Vail, founder of the Bell System, the greatest information empire of all time, and a capitalist whose faith in Soviet-style central planning set the course of every information industry thereafter.Explaining how invention begets industry and industry begets empire—a progress often blessed by government, typically with stifling consequences for free expression and technical innovation alike—Wu identifies a time-honored pattern in the maneuvers of today’s great information powers: Apple, Google, and an eerily resurgent AT&T. A battle royal looms for the Internet’s future, and with almost every aspect of our lives now dependent on that network, this is one war we dare not tune out.Part industrial exposé, part meditation on what freedom requires in the information age, The Master Switch is a stirring illumination of a drama that has played out over decades in the shadows of our national life and now culminates with terrifying implications for our future.

    He announced to the public his grandiose plans for the thousands of acres he had secretly purchased.For the eighteen months prior to the announcement, Walt entrusted a small group of men to covertly make these purchases. Next, they were tasked with drafting a legislative act to submit to the state of Florida that would allow Disney to wield nearly absolute legal control over the property under a quasi-government municipality.Staying true to its storytelling roots, Disney wove a tale of mystery centered around a high-ranking CIA operative, who was rumored to have been, just a few short years before, the paymaster behind the Bay of Pigs Invasion in Cuba.This savvy and well-connected CIA agent became the de facto leader for the group of Disney executives and attorneys who orchestrated and executed a nearly perfect plan to keep Disney’s identity a secret from the public by utilizing aliases, shell corporations, and meandering travel itineraries, all in an effort to protect the company’s identity during the land acquisition process.As told through the personal notes and files from the key figures involved in the project, Buying Disney’s World details the story of how Walt Disney World came to be, like you’ve never heard before.From conception to construction and everything in between—including how a parcel of land within Disney’s Fort Wilderness Resort was acquired during a high-stakes poker game—explore how the company most famous for creating Mickey Mouse acquired central Florida’s swamps, orange groves, and cow pastures to build a Disney fiefdom and a Magic Kingdom.

    But for thousands of years, people have done things like this—and things that make radioactive underpants seem downright sensible! In their hit podcast, Sawbones, Sydnee and Justin McElroy breakdown the weird and wonderful way we got to modern healthcare. And some of the terrifying detours along the way.Every week, Dr. Sydnee McElroy and her husband Justin amaze, amuse, and gross out (depending on the week) hundreds of thousands of avid listeners to their podcast, Sawbones. Consistently rated a top podcast on iTunes, with over 15 million total downloads, this rollicking journey through thousands of years of medical mishaps and miracles is not only hilarious but downright educational. While you may never even consider applying  boiled weasel to your forehead (once the height of sophistication when it came to headache cures), you will almost certainly face some questionable medical advice in your everyday life (we’re looking at you, raw water!) and be better able to figure out if this is a miracle cure (it’s not) or a scam. Table of Contents:Part One: The Unnerving The Resurrection Men Fun w Galvanism Weird Weight Loss Miracle Cure: Opium Black Plague Heroes of Misguided Medicine: Pliny the Elder Erectile Dysfunction The Doctor Is In: Listener Questions Answered Don’t Drill a Hole in Your HeadPart Two: The Gross Mummy Medicine The Guthole Bromance The Unkillable Phineas Gage Max Drank Poopy Water Heroes of Misguided Medicine: Robert Liston Golden Showers of Health Miracle Cure-All: Radium Dr. John Romulus Brinkley The Doctor Is In Q&A Just (Four) Humour Me The Camel Dung MiraclePart Three: The Weird The Dancing Plague Bad Medicine: Tobacco for Health The Seasick-Proof Saloon Miracle Cure-All: Vinegar The Doctor Is In Q&A Heroes of Misguided MedicinePart Four: The Awesome The Poison Squad Bad Medicine: Self Experimentation Eat Your Chocolate! Heroes of Misguided Medicine Parrot Fever Miracle Cure-All: Honey The Miraculous Polio Vaccine The Doctor Is In

    In June 1962, a young biologist in Philadelphia, using tissue extracted from an aborted fetus from Sweden, produced safe, clean cells that allowed the creation of vaccines against rubella and other common childhood diseases. Two years later, in the midst of a devastating German measles epidemic, his colleague developed the vaccine that would one day wipe out homegrown rubella. The rubella vaccine and others made with those fetal cells have protected more than 150 million people in the United States, the vast majority of them preschoolers. The new cells and the method of making them also led to vaccines that have protected billions of people around the world from polio, rabies, chicken pox, measles, hepatitis A, shingles and adenovirus. Meredith Wadman’s masterful account recovers not only the science of this urgent race, but also the political roadblocks that nearly stopped the scientists. She describes the terrible dilemmas of pregnant women exposed to German measles and recounts testing on infants, prisoners, orphans, and the intellectually disabled, which was common in the era. These events take place at the dawn of the battle over using human fetal tissue in research, during the arrival of big commerce in campus labs, and as huge changes take place in the laws and practices governing who “owns” research cells and the profits made from biological inventions. It is also the story of yet one more unrecognized woman whose cells have been used to save countless lives. With another frightening virus imperiling pregnant women on the rise today, no medical story could have more human drama, impact, or urgency today than The Vaccine Race.

    Join first responders and ER doctors as they encounter life-or-death situations, putting their training and beliefs to the test. Be uplifted as you meet real-life angels, such as Elton, a daring highway patrolman who risks it all to prevent disaster James, the orthopedic tech with a God-given talent for mending hearts Shep, a principled fire captain whose most important lesson spares one of his own Denton, the tireless paramedic who rescues an injured man...from a hospital Maybelle, a faithful nursery volunteer who makes a life-saving diagnosis As you read these heart-pounding stories of faith in the face of impossible odds, you'll be reminded that a loving and merciful God appoints angels, those you can and cannot see, to watch over you and intervene on your behalf.

    In Missing Microbes, Dr. Martin Blaser invites us into the wilds of the human microbiome where for hundreds of thousands of years bacterial and human cells have existed in a peaceful symbiosis that is responsible for the health and equilibrium of our body. Now, this invisible eden is being irrevocably damaged by some of our most revered medical advances—antibiotics—threatening the extinction of our irreplaceable microbes with terrible health consequences. Taking us into both the lab and deep into the fields where these troubling effects can be witnessed firsthand, Blaser not only provides cutting edge evidence for the adverse effects of antibiotics, he tells us what we can do to avoid even more catastrophic health problems in the future. http://us.macmillan.com/missingmicrob...

    In the span of twelve hours, lives can be lost, life-altering medical treatment decisions made, and dreams fulfilled or irrevocably stolen. In Brown’s skilled hands--as both a dedicated nurse and an insightful chronicler of events--we are given an unprecedented view into the individual struggles as well as the larger truths about medicine in this country, and by shift’s end, we have witnessed something profound about hope and healing and humanity. Every day, Theresa Brown holds patients' lives in her hands. On this day there are four. There is Mr. Hampton, a patient with lymphoma to whom Brown is charged with administering a powerful drug that could cure him--or kill him; Sheila, who may have been dangerously misdiagnosed; Candace, a returning patient who arrives (perhaps advisedly) with her own disinfectant wipes, cleansing rituals, and demands; and Dorothy, who after six weeks in the hospital may finally go home. Prioritizing and ministering to their needs takes the kind of skill, sensitivity, and, yes, humor that enable a nurse to be a patient’s most ardent advocate in a medical system marked by heartbreaking dysfunction as well as miraculous success.

    From the conquest of Mexico by smallpox as much as by the Spanish, to the bubonic plague in China, to the typhoid epidemic in Europe, the history of disease is the history of humankind. With the identification of AIDS in the early 1980s, another chapter has been added to this chronicle of events, which William McNeill explores in his new introduction to this updated editon.Thought-provoking, well-researched, and compulsively readable, Plagues and Peoples is that rare book that is as fascinating as it is scholarly, as intriguing as it is enlightening. "A brilliantly conceptualized and challenging achievement" (Kirkus Reviews), it is essential reading, offering a new perspective on human history.

    "A story of tragedy and courage that should be reade by all."—Dallas Morning News.

    R. Reid shows how all the other industrialized democracies have achieved something the United States can’t seem to do: provide health care for everybody at a reasonable cost. In his global quest to find a possible prescription, Reid visits wealthy, free market, industrialized democracies like our own—including France, Germany, Japan, the U.K., and Canada—where he finds inspiration in example. Reid sees problems too: He finds poorly paid doctors in Japan, endless lines in Canada, mistreated patients in Britain, spartan facilities in France. In addition to long-established systems, Reid also studies countries that have carried out major health care reform. The first question facing these countries—and the United States, for that matter—is an ethical issue: Is health care a human right?The Healing of America lays bare the moral question at the heart of our troubled system, dissecting the misleading rhetoric surrounding the health care debate: Is health care a human right?