In every age, in every part of the world, people have pursued intoxication with plants, alcohol, and other mind-altering substances. In fact, this behavior has so much force and persistence that it functions much like our drives for food, sleep, and sex. This "fourth drive," says psychopharmacologist Ronald K. Siegel, is a natural part of our biology, creating the irrepressible demand for intoxicating substances.In Intoxication Siegel draws upon his 20 years of groundbreaking research to provide countless examples of the intoxication urge in humans, animals, and even insects. The detailed observations of his so-called psychonauts--study participants trained to explicitly describe their drug experiences--as well as numerous studies with animals have helped him to identify the behavior patterns induced by different intoxicants. Presenting his conclusions on the biological as well as cultural reasons for the pursuit of intoxication and showing that personality and guidance often define the outcome of a drug experience, Siegel offers a broad understanding of the intoxication phenomenon as well as recommendations for curbing the negative aspects of drug use in Western culture by designing safe intoxicants.

    In this groundbreaking analysis, over thirty of the most popular treatments—acupuncture, homeopathy, aromatherapy, reflexology, chiropractic, and herbal medicines—are examined for their benefits and potential dangers. Questions answered include: What works and what doesn't? What are the secrets, and what are the lies? Who can you trust, and who is ripping you off? Can science decide what is best, or do the old wives' tales really tap into ancient, superior wisdom?In their scrutiny of alternative and complementary cures, authors Simon Singh and Edzard Ernst also strive to reassert the primacy of the scientific method as a means for determining public health practice and policy.

    Start now. All it takes is 2 minutes of your time.'I read this book yesterday and I've done three things today and that is testament to Martin's brilliant vision and ideas. Now it's your turn!' Chris Packham'Once, plastic was the miracle material. Now it's the monster. We all need to cut down our plastic consumption and join Martin's #2minutesolution anti-plastic movement. I'm in.' Julia BradburyOpen this book with your children, give it to your friends. Share your #2minutesolution on twitter and instagram and inspire others. Martin Dorey, anti-plastics expert, has been working to save our beaches from plastic for the past 10 years. His Beach Clean Foundation and global call to arms #2minutebeachclean has been taken up by people all over the world, and has proven that collective small actions can add up to a big difference. Together we can fix this.

    Cells are built out of molecular circuits that perform logical operations, as electronic devices do, but with unique properties. Bray argues that the computational juice of cells provides the basis of all the distinctive properties of living systems: it allows organisms to embody in their internal structure an image of the world, and this accounts for their adaptability, responsiveness, and intelligence.In Wetware, Bray offers imaginative, wide-ranging and perceptive critiques of robotics and complexity theory, as well as many entertaining and telling anecdotes. For the general reader, the practicing scientist, and all others with an interest in the nature of life, the book is an exciting portal to some of biology’s latest discoveries and ideas.

    In this exciting book, paleontologist Phillip Manning presents the most astonishing dinosaur fossil excavations of the past 100 years—including the recent discovery of a remarkably intact dinosaur mummy in the Badlands of North Dakota. Bone structure is just the beginning of our knowledge today, thanks to amazing digs like these. Drawing on new breakthroughs and cutting-edge techniques of analysis, Dr. Manning takes us on a thrilling, globe-spanning tour of dinosaur mummy finds—from the first such excavation in 1908 to a baby dinosaur unearthed in 1980, from a dino with a heart in South Dakota to titanosaur embryos in Argentina. And he discusses his own groundbreaking analysis of "Dakota," discovered by Tyler Lyson. Using state-of-the-art technology to scan and analyse this remarkable discovery, National Geographic and Dr. Manning create an incredibly lifelike portrait of Dakota. The knowledge to be gained from this exceedingly rare find, and those that came before it, will intrigue dinosaur-loving readers of all ages.

    Mary T. Newport has demonstrated through her care for her husband that there is hope, relief, and perhaps a cure.

    We have all benefited from the medical discoveries of primate research--vaccines for polio, rubella, and hepatitis B are just a few. But we have also learned more in recent years about how intelligent apes and monkeys really are: they can speak to us with sign language, they can even play video games (and are as obsessed with the games as any human teenager). And activists have also uncovered widespread and unnecessarily callous treatment of animals by researchers (in 1982, a Silver Spring lab was charged with 17 counts of animal cruelty). It is a complex issue, made more difficult by the combative stance of both researchers and animal activists. In The Monkey Wars, Deborah Blum gives a human face to this often caustic debate--and an all-but-human face to the subjects of the struggle, the chimpanzees and monkeys themselves. Blum criss-crosses America to show us first hand the issues and personalities involved. She offers a wide-ranging, informative look at animal rights activists, now numbering some twelve million, from the moderate Animal Welfare Institute to the highly radical Animal Liberation Front (a group destructive enough to be placed on the FBI's terrorist list). And she interviews a wide variety of researchers, many forced to conduct their work protected by barbed wire and alarm systems, men and women for whom death threats and hate mail are common. She takes us to Roger Fouts's research center in Ellensburg, Washington, where we meet five chimpanzees trained in human sign language, and we visit LEMSIP, a research facility in New York State that has no barbed wire, no alarms--and no protesters chanting outside--because its director, Jan Moor-Jankowski, listens to activists with respect and treats his animals humanely. And along the way, Blum offers us insights into the many side-issues involved: the intense battle to win over school kids fought by both sides, and the danger of transplanting animal organs into humans. As it stands now, Blum concludes, the research community and its activist critics are like two different nations, nations locked in a long, bitter, seemingly intractable political standoff....But if you listen hard, there really are people on both sides willing to accept and work within the complex middle. When they can be freely heard, then we will have progressed to another place, beyond this time of hostilities. In The Monkey Wars, Deborah Blum gives these people their voice.

    Lieberman illuminates how these ongoing changes have brought many benefits, but also have created novel conditions to which our bodies are not entirely adapted, resulting in a growing incidence of obesity and new but avoidable diseases, including type-2 diabetes. He proposes that many of these chronic illnesses persist and in some cases are intensifying because of "dysevolution," a pernicious dynamic whereby only the symptoms rather than the causes of these maladies are treated. And finally—provocatively—he advocates the use of evolutionary information to help nudge, push, and sometimes oblige us to create a more salubrious environment.(With charts and line drawings throughout.)From the Hardcover edition.

    So do our politicians.We're not listening.And no one is listening to us.Despite living in a world where technology allows constant digital communication and opportunities to connect, it seems no one is really listening or even knows how. And it’s making us lonelier, more isolated, and less tolerant than ever before. A listener by trade, New York Times contributor Kate Murphy wanted to know how we got here.In this always illuminating and often humorous deep dive, Murphy explains why we’re not listening, what it’s doing to us, and how we can reverse the trend. She makes accessible the psychology, neuroscience, and sociology of listening while also introducing us to some of the best listeners out there (including a CIA agent, focus group moderator, bartender, radio producer, and top furniture salesman). It’s time to stop talking and start listening.

    Harlen Bretz walked the dry scabland channels of eastern Washington in the 1920s, it dawned on him that he was viewing a landscape sculpted by water. Lots of water. A flood of catastrophic proportions. Glacial Lake Missoula and Its Humongous Floods tells the gripping tale of a huge Ice Age lake that drained suddenly--not just once but repeatedly--and reshaped the landscape of the Northwest. The narrative follows the path of the floodwaters as they raged from western Montana across the Idaho Panhandle, then scoured through eastern Washington and down the Columbia Gorge to the Pacific Ocean. This is also the story of geologists grappling with scientific controversy--"of how personalities, pride, and prejudice sometimes superseded scientific evidence."

    With a brief history of the whole universe, you’ll be left scratching your head and gazing up in absolute wonder.Everything you thought you could never understand about the universe is explained in plain-old filthy English. Giving you a little taste of the glorious reality you inhabit by providing an introduction to some of the incredible stuff out there.Over 50 chapters on subjects including:What actually happened during the big bangblack holestime travelthe degenerate astronomer who drank all night and died from holding his bladder… and also lost his nose in a duel the things you take for granted until you really think about them; like matter – what the fuck is all this shit that we are?Space is Cool as Fuck features more than 100 wild artworks, photographs and illustrations from 40 international young artists curated by brilliant designer Cynthia Larenas. From hand-picked unknowns like Kate Kurucz and Adrian du P.B. through up-and-comers like Aida Azin, Waiton Fong and Cal Sinadinovic, to the more established Kareena Zerefos, Chrissie Abbot, Uno Moralez, Regan Tanamui (Ha Ha) and Marina Zumi, each artist brings their own aesthetic to the majesty and wonder of space giving the book its exquisitely eclectic style.For more information on Lost the Plot, visit ltpbooks.com

    Fast Tract Digestion Heartburn is the first book to define and address the real cause of acid reflux. Acid reflux occurs as a result of digestive malabsorption of five difficult-to-digest carbohydrates. It leads to the overgrowth of gas-producing bacteria in the small intestine and the gas pressure drives acid reflux. Dropping a Mentos into a bottle of Coke is the perfect illustration of this phenomenon. Unfortunately, PPI drugs do not address the real cause, but also cause serious side effects including vitamin and mineral malabsorption, bone fractures, pneumonia, low blood magnesium levels, bacterial overgrowth, C diff infection and pneumonia as explained in the book.Fast Tract Digestion Heartburn offers science-based food choices and recipes (Fast Tract Diet) to limit the five difficult-to-digest carbohydrates, so that you can feel relief within a few days Also, it enables you to self-manage all of the symptoms of acid reflux going forward. The Fast Tract Diet is based on a scientific formula called Fermentation Potential (FP). FP is the key measure regardless of the carbohydrate count. Limiting foods with high FP will help control the overgrowth of bacteria in the small intestine and, as a result, acid reflux. The Fast Tract Diet was clinically tested on reflux sufferers in the Boston area. The results were overwhelming and proved the effectiveness of the diet as an alternative to proton pump inhibitor drugs.

    He solidified his standing as the nation's foremost political forecaster with his near perfect prediction of the 2012 election. Silver is the founder and editor in chief of FiveThirtyEight.com. Drawing on his own groundbreaking work, Silver examines the world of prediction, investigating how we can distinguish a true signal from a universe of noisy data. Most predictions fail, often at great cost to society, because most of us have a poor understanding of probability and uncertainty. Both experts and laypeople mistake more confident predictions for more accurate ones. But overconfidence is often the reason for failure. If our appreciation of uncertainty improves, our predictions can get better too. This is the "prediction paradox": The more humility we have about our ability to make predictions, the more successful we can be in planning for the future.In keeping with his own aim to seek truth from data, Silver visits the most successful forecasters in a range of areas, from hurricanes to baseball, from the poker table to the stock market, from Capitol Hill to the NBA. He explains and evaluates how these forecasters think and what bonds they share. What lies behind their success? Are they good-or just lucky? What patterns have they unraveled? And are their forecasts really right? He explores unanticipated commonalities and exposes unexpected juxtapositions. And sometimes, it is not so much how good a prediction is in an absolute sense that matters but how good it is relative to the competition. In other cases, prediction is still a very rudimentary-and dangerous-science.Silver observes that the most accurate forecasters tend to have a superior command of probability, and they tend to be both humble and hardworking. They distinguish the predictable from the unpredictable, and they notice a thousand little details that lead them closer to the truth. Because of their appreciation of probability, they can distinguish the signal from the noise.

    In How Not to Be Wrong, Jordan Ellenberg shows us how terribly limiting this view is: Math isn’t confined to abstract incidents that never occur in real life, but rather touches everything we do—the whole world is shot through with it.Math allows us to see the hidden structures underneath the messy and chaotic surface of our world. It’s a science of not being wrong, hammered out by centuries of hard work and argument. Armed with the tools of mathematics, we can see through to the true meaning of information we take for granted: How early should you get to the airport? What does “public opinion” really represent? Why do tall parents have shorter children? Who really won Florida in 2000? And how likely are you, really, to develop cancer?How Not to Be Wrong presents the surprising revelations behind all of these questions and many more, using the mathematician’s method of analyzing life and exposing the hard-won insights of the academic community to the layman—minus the jargon. Ellenberg chases mathematical threads through a vast range of time and space, from the everyday to the cosmic, encountering, among other things, baseball, Reaganomics, daring lottery schemes, Voltaire, the replicability crisis in psychology, Italian Renaissance painting, artificial languages, the development of non-Euclidean geometry, the coming obesity apocalypse, Antonin Scalia’s views on crime and punishment, the psychology of slime molds, what Facebook can and can’t figure out about you, and the existence of God.Ellenberg pulls from history as well as from the latest theoretical developments to provide those not trained in math with the knowledge they need. Math, as Ellenberg says, is “an atomic-powered prosthesis that you attach to your common sense, vastly multiplying its reach and strength.” With the tools of mathematics in hand, you can understand the world in a deeper, more meaningful way. How Not to Be Wrong will show you how.