Somehow, within each of our brains, billions of neurons work to create our conscious experience. How does this happen? Why do we experience life in the first person? After over twenty years researching the brain, world-renowned neuroscientist Anil Seth puts forward a radical new theory of consciousness and self. His unique theory of what it means to 'be you' challenges our understanding of perception and reality and it turns what you thought you knew about yourself on its head.'Awe-inspiring and humane.' NEW STATESMAN (Books of the Year)'Fascinating.' FINANCIAL TIMES (Books of the Year)'Profound.' GUARDIAN (Books of the Year)'Brilliant.' CLAIRE TOMALIN, NEW YORK TIMES'Outstanding.' PSYCHOLOGY TODAY 'Amazing . . . a brilliant read.'RUSSELL BRAND'Beautifully written, crystal clear, deeply insightful.'DAVID EAGLEMAN, Pulitzer Prize-nominated author of Livewired'Offers us new cause for astonishment and wonder.'ANNAKA HARRIS, author of Conscious'A fascinating book. A joy to read.'NIGEL WARBURTON'Truly compelling.'PROFESSOR KARL FRISTON, Universty College London'A wonderfully accessible and comprehensive account.'SEAN CARROLL, author of Something Deeply Hidden

    For the healthy but overworked majority, this might sound like an enviable condition, but for Henry, the inability to stay awake is profoundly disabling, especially as it is accompanied by mysterious collapses called cataplexy, poor night-time sleep, hallucinations and sleep paralysis.A writer and biologist, Nicholls explores the science of disordered sleep, discovering that around half of us will experience some kind of sleep dysfunction in our lives. From a CBT course to tackle insomnia to a colony of narcoleptic Dobermans, his journey takes him through the half-lit world of sleep to genuine revelations about his own life and health.Told with humour and intelligence, Sleepyhead uses personal reflections, interviews with those with sleep disorders and the people who study them, anecdotes from medical history and insights from art and literature to change the way we understand our sleeping hours.

    Beginning with the above questions, she began informally researching every affliction that she encountered in humans to learn whether it happened with animals, too. And usually, it did: dinosaurs suffered from brain cancer, koalas can catch chlamydia, reindeer seek narcotic escape in hallucinogenic mushrooms, stallions self-mutilate, and gorillas experience clinical depression. Natterson-Horowitz and science writer Kathryn Bowers have dubbed this pan-species approach to medicine zoobiquity. Here, they present a revelatory understanding of what animals can teach us about the human body and mind, exploring how animal and human commonality can be used to diagnose, treat, and heal patients of all species.

    It is believed that we must commit 10,000 hours to master a skill.  According to Lieberman, each of us has spent 10,000 hours learning to make sense of people and groups by the time we are ten.  Social argues that our need to reach out to and connect with others is a primary driver behind our behavior.  We believe that pain and pleasure alone guide our actions.  Yet, new research using fMRI – including a great deal of original research conducted by Lieberman and his UCLA lab -- shows that our brains react to social pain and pleasure in much the same way as they do to physical pain and pleasure.  Fortunately, the brain has evolved sophisticated mechanisms for securing our place in the social world.  We have a unique ability to read other people’s minds, to figure out their hopes, fears, and motivations, allowing us to effectively coordinate our lives with one another.  And our most private sense of who we are is intimately linked to the important people and groups in our lives.  This wiring often leads us to restrain our selfish impulses for the greater good.  These mechanisms lead to behavior that might seem irrational, but is really just the result of our deep social wiring and necessary for our success as a species.   Based on the latest cutting edge research, the findings in Social have important real-world implications.  Our schools and businesses, for example, attempt to minimalize social distractions.  But this is exactly the wrong thing to do to encourage engagement and learning, and literally shuts down the social brain, leaving powerful neuro-cognitive resources untapped.  The insights revealed in this pioneering book suggest ways to improve learning in schools, make the workplace more productive, and improve our overall well-being.

    But doctors’ emotional responses to the life-and-death dramas of everyday practice have a profound impact on medical care. And while much has been written about the minds and methods of the medical professionals who save our lives, precious little has been said about their emotions. In What Doctors Feel, Dr. Danielle Ofri has taken on the task of dissecting the hidden emotional responses of doctors, and how these directly influence patients.How do the stresses of medical life—from paperwork to grueling hours to lawsuits to facing death—affect the medical care that doctors can offer their patients? Digging deep into the lives of doctors, Ofri examines the daunting range of emotions—shame, anger, empathy, frustration, hope, pride, occasionally despair, and sometimes even love—that permeate the contemporary doctor-patient connection. Drawing on scientific studies, including some surprising research, Dr. Danielle Ofri offers up an unflinching look at the impact of emotions on health care.With her renowned eye for dramatic detail, Dr. Ofri takes us into the swirling heart of patient care, telling stories of caregivers caught up and occasionally torn down by the whirlwind life of doctoring. She admits to the humiliation of an error that nearly killed one of her patients and her forever fear of making another. She mourns when a beloved patient is denied a heart transplant. She tells the riveting stories of an intern traumatized when she is forced to let a newborn die in her arms, and of a doctor whose daily glass of wine to handle the frustrations of the ER escalates into a destructive addiction. But doctors don’t only feel fear, grief, and frustration. Ofri also reveals that doctors tell bad jokes about “toxic sock syndrome,” cope through gallows humor, find hope in impossible situations, and surrender to ecstatic happiness when they triumph over illness.  The stories here reveal the undeniable truth that emotions have a distinct effect on how doctors care for their patients. For both clinicians and patients, understanding what doctors feel can make all the difference in giving and getting the best medical care.

    Administered off-label in small daily doses (0.5 to 4.5 mg), this generic drug is extremely affordable and presents few known side effects. So why has it languished in relative medical obscurity? The LDN Book explains the drug’s origins, its primary mechanism, and the latest research from practicing physicians and pharmacists as compiled by Linda Elsegood of The LDN Research Trust, the world’s largest LDN charity organization with over 19,000 members worldwide. Featuring ten chapters contributed by medical professionals on LDN’s efficacy and two patient-friendly appendices, The LDN Book is a comprehensive resource for doctors, pharmacists, and patients who want to learn more about how LDN is helping people now, and a clarion call for further research that could help millions more.

    His beat is a nursing home in Miami that some would dismiss as “God’s waiting room.” Nothing in the young doctor’s medical training had quite prepared him for what he was to discover there. As Agronin first learned from ninety-eight-year-old Esther and, later, from countless others, the true scales of aging aren’t one-sided—you can’t list the problems without also tallying the hopes and promises. Drawing on moving personal experiences and in-depth interviews with pioneers in the field, Agronin conjures a spellbinding look at what aging means today—how our bodies and brains age, and the very way we understand aging.

    Amy chronicles her harrowing medical journey from the first misdiagnosis to her astonishing recovery after her heart transplant, which is made all the more dramatic by the romantic bedside courtship with her future husband, and her uncompromising desire to become a mother. She presents a patient's perspective of life after a heart transplant with honesty.

    The outlook was grim. Then she took part in Genentech's clinical trials for a new drug. Five years later she remains cancer-free.Her-2 is the biography of Herceptin, the drug that provoked dramatic responses in Barbara Bradfield and other women in the trials and that offers promise for hundreds of thousands of breast cancer patients. Unlike chemotherapy or radiation, Herceptin has no disabling side effects. It works by inactivating Her-2/neu--a protein that makes cancer cells grow especially quickly-- produced by a gene found in 25 to 30 percent of all breast tumors. Herceptin caused some patients' cancers to disappear completely; in others, it slowed the progression of the disease and gave the women months or years they wouldn't otherwise have had. Herceptin is the first treatment targeted at a gene defect that gives rise to cancer. It marks the beginning of a new era of treatment for all kinds of cancers.Robert Bazell presents a riveting account of how Herceptin was born. Her-2 is a story of dramatic discoveries and strong personalities, showing the combination of scientific investigation, money, politics, ego, corporate decisions, patient activism, and luck involved in moving this groundbreaking drug from the lab to a patient's bedside. Bazell's deft portraits introduce us to the remarkable people instrumental in Herceptin's history, including Dr. Dennis Slamon, the driven UCLA oncologist who played the primary role in developing the treatment; Lily Tartikoff, wife of television executive Brandon Tartikoff, who tapped into Hollywood money and glamour to help fund Slamon's research; and Marti Nelson, who inspired the activists who lobbied for a "compassionate use" program that would allow women outside the clinical trials to have access to the limited supplies of Herceptin prior to FDA approval of the drug. And throughout there are the stories of the heroic women with advanced breast cancer who volunteered for the trials, risking what time they had left on an unproven treatment. Meticulously researched, written with clarity and compassion, Her-2 is masterly reporting on cutting-edge science.

    We rely on them every day of our lives. They make us who we are. And yet the truth is they are far from being the accurate record of the past we like to think they are. True, we can all admit to having suffered occasional memory lapses, such as entering a room and immediately forgetting why, or suddenly being unable to recall the name of someone we've met dozens of times. But what if our minds have the potential for more profound errors, that enable the manipulation or even outright fabrication of our memories?In The Memory Illusion, forensic psychologist and memory expert Dr Julia Shaw uses the latest research to show the astonishing variety of ways in which our brains can indeed be led astray. She shows why we can sometimes misappropriate other people's memories, subsequently believing them to be our own. She explains how police officers can imprison an innocent man for life on the basis of many denials and just one confession. She demonstrates the way radically false memories can be deliberately implanted, leading people to believe they had tea with Prince Charles, or committed crimes that never happened. And she reveals how, in spite of all this, we can improve our memory through simple awareness of its fallibility. Fascinating and unnerving in equal measure, The Memory Illusion offers a unique insight into the human brain, challenging you to question how much you can ever truly know about yourself.

    Wendy Suzuki one day woke up and realized she didn’t have a life. As an almost-40-year-old award-winning college professor, world-renowned neuroscientist, she had—what many considered—everything: tenure as a professor at New York University; her own very successful neuroscience research lab; prizes for scientific discoveries on cognition and memory; articles published in prestigious scientific journals. As a woman and a scientist, she was the envy of her peers and lauded by her superiors. On paper, she had a stellar career and an impeccable record. What could she possibly be missing? Everything else. Suzuki was overweight. She was tired. She was lonely, had strained work relationships, and for the first time in her life, completely without direction. So she resolved to change her life. The first step--get moving. Everyone knows that exercise makes you feel better—that when you hit the gym despite the dread, you leave in a better mood. Healthy Brain, Happy Life offers the real science of how exercise effects your mind. Using Wendy’s journey from frumpy, fat and frustrated to fit and fabulous as a guide, Healthy Brain offers not just the HOWS of making exercise an important part of life, but the WHYS of the benefits it brings. But movement is just the first step to being Brain Healthy. Once you get your body and mind hooked on exercise, you bring in practices in mindfullness to calm stress and allow your minds to wander to unlock creativity. As your brain begins to change (something called neuroplasticity), the benefits build--you get fitter, improve your memory, increase your ability to work quickly and move from task to task easily. Along with Dr. Suzuki’s 4 minute Brain Hacks, Healthy Brain, Happy Life offers a simple program for changing your life, straight from a leading scientist’s personal experience.

     If Buddha had been in an MRI machine and not under the Bodhi tree when he attained enlightenment, what would we have seen on the monitor? Dr. Kevin Nelson offers an answer to that question that is beyond what any scientist has previously encountered on the borderlands of consciousness. In his cutting-edge research, Nelson has discovered that spiritual experiences take place in one of the most primitive areas of the brain. In this eloquent, inspired, and reverent book, he relates the moving stories of patients and research subjects, brain scan analysis, evolutionary biology, and beautiful examples of transcendence from literature to reveal the machinery in our heads that enables us to perceive miracles-whether you are an atheist, Buddhist, or the most devout Catholic. The patients and people Nelson discuss have had an extremely diverse set of spiritual experiences, from arguing with the devil sitting at the foot of their hospital bed to seeing the universe synchronize around the bouncing of the ball in a pinball machine. However, the bizarre experiences don't make the people seem like freaks; they seem strangely very much like us, in surprising ways. Ultimately Nelson makes clear that spiritual experiences are not the exception in human life, but rather an inescapable and precious part of every one of us.

    He is one of the foremost figures of contemporary neuroscience, and his decades-long quest to understand the inner workings of the brain’s memory machine has begun to pay off. Award-winning journalist Terry McDermott spent nearly two years observing Lynch at work and now gives us a fascinating and dramatic account of daily life in his lab—the highs and lows, the drudgery and eureka moments, the agonizing failures. He provides detailed, lucid explanations of the cutting-edge science that enabled Lynch to reveal the inner workings of the molecular machine that manufactures memory. After establishing the building blocks, Lynch then set his sights on uncovering the complicated structure of memory as it is stored across many neurons. Adding practical significance to his groundbreaking work, Lynch discovered a class of drugs that could fix the memory machine when it breaks, drugs that would enhance brain function during the memory process and that hold out the possibility of cures for a wide range of neurological conditions, including Alzheimer’s disease, Parkinson’s disease, and attention deficit hyperactivity disorder. Here is an essential story of science, scientists, and scientific achievement—galvanizing in the telling and thrilling in its far-reaching implications.

    But in the past few years, they've discovered that glial cells are extraordinarily important. In fact, they may hold the key to understanding intelligence, treating psychiatric disorders and brain injuries and perhaps even curing fatal conditions like Alzheimer's, Parkinson's, and Lou Gehrig's Disease. In The Root of Thought, leading neuroscientist Dr. Andrew Koob reveals what we've learned about these remarkable cells, from their unexpected role in information storage to their function as adult stem cells that can keep your brain growing and adapting longer than scientists ever imagined possible. Ranging from fruit flies to Einstein, Koob reveals the surprising correlation between intelligence and the brain's percentage of glial cells - and why these cells' unique wavelike communications may be especially conducive to the fluid information processing human beings depend upon. You'll learn how crucial glial cells grow and develop... why almost all brain tumors are comprised of glial cells and the potential implications for treatment... even the apparent role of glial cells in your every thought and dream!

    It reviews the historical context from which the field emerged, focusing on behavioural implications, and intergrating new developments in cognitive neuroscience. The authors cover current neuroimaging techniques such as PET, SPECT, EEG and MEG. This edition has been updated to incorporate present thinking within hemispheric asymmetry.