Devlin's Textbook of Biochemistry with Clinical Correlations presents the biochemistry of mammalian cells, relates events at a cellular level to the subsequent physiological processes in the whole animal, and cites examples of human diseases derived from aberrant biochemical processes. The organization and content are tied together to provide students with the complete picture of biochemistry and how it relates to humans. Loaded with new material and chapters and brimming with detailed, full-color illustrations that clearly explain associated concepts, this sixth edition is an indispensable tool for students and professionals in the medical or health sciences. Key Features of the Sixth Edition Over 250 Clinical Correlations highlighting the significance of the biochemistry to clinical conditions and diseases MCAT-Style Questions with annontated answers in every chapter - in a format similar to that used by the National Board of Medical Examiners More than 1,200 high-quality, full-color illustrations A concise appendix reviewing important Organic Chemistry Concepts New to the Sixth Edition: Fully Updated with a significant revision of all chapters and major topics Two new chapters: Fundamentals of Signal Transduction and Cell Cycle, Programmed Cell Death, and Cancer A Glossary that explains important biochemical terms New sections on the Basal Lamina Protein Complex and Molecular Motors

    The first volume in this annual series of the best writing by Americans, meticulously selected by bestselling author James Gleick, one of the foremost chronicles of scientific social history, debuts with a stellar collection of writers and thinkers.  Many of these cutting-edge essays offer glimpses of new realms of discovery and thought, exploring territory that is unfamiliar to most of us, or finding the unexpected in the midst of the familiar.  Nobel Laureate physicist Steven Weinberg challenges the idea of whether the universe has a designer; Pulitzer Prize winner Natalie Angier reassesses caveman (and-woman) couture; bestselling author and Darwinian theorist Stephen Jay Gould makes a claim for the man whose ideas Darwin discredited; Timothy Ferris proposes a realistic alternative to wrap-speed interseller travel; neurologist and bestselling author Oliver Sacks reminisces about his first loves-chemistry and math.  This diverse, stimulating and accessible collection is required reading for anyone who wants to travel to the frontier of knowledge.

    Everything that makes you you, and all your experiences of the world, are somehow conjured up by 1.4 kilograms of grey matter inside your skull. That might seem impossible, but science has advanced so much that we now understand not just its structures and inner workings but also how it can give rise to perception, consciousness, emotions, memories, intelligence, sleep and more.HOW YOUR BRAIN WORKS explores the amazing world inside your head. Discover the evolution and anatomy of the brain. Learn how we can peer inside it and watch it at work, and how the latest technology can allow us to control our minds and those of others.ABOUT THE SERIESNew Scientist Instant Expert books are definitive and accessible entry points to the most important subjects in science; subjects that challenge, attract debate, invite controversy and engage the most enquiring minds. Designed for curious readers who want to know how things work and why, the Instant Expert series explores the topics that really matter and their impact on individuals, society, and the planet, translating the scientific complexities around us into language that's open to everyone, and putting new ideas and discoveries into perspective and context.

    The germ revolution came after two decades of scientific virtuosity, outstanding feats of intellectual courage and bitter personal rivalries, doctors at last recognised that infectious diseases are caused by mircoscopic organisms.

    They will also develop a deeper understanding of the many interconnections that exist among the different areas of psychology. Goodwin's book not only provides accounts of the lives and contributions of psychology's pioneers set into historical context; it also contains original writings by these psychologists, interwoven with informative comments from the author. The text is written in a conversational and engaging style with discrete attention to recent scholarship in the history of psychology, especially that of the past 150 years.

    Barash, there are even more things that we don't know, genuine evolutionary mysteries that perplex the best minds in biology. Paradoxically, many of these mysteries are very close to home, involving some of the most personalaspects of being human.Homo Mysterious examines a number of these evolutionary mysteries, exploring things that we don't yet know about ourselves, laying out the best current hypotheses, and pointing toward insights that scientists are just beginning to glimpse. Why do women experience orgasm? Why do men have a shorterlifespan than women? Why does homosexuality exist? Why does religion exist in virtually every culture? Why do we have a fondness for the arts? Why do we have such large brains? And why does consciousness exist? Readers are plunged into an ocean of unknowns--the blank spots on the human evolutionarymap, the terra incognita of our own species--and are introduced to the major hypotheses that currently occupy scientists who are attempting to unravel each puzzle (including some solutions proposed here for the first time). Throughout the book, readers are invited to share the thrill of science atits cutting edge, a place where we know what we don't know, and, moreover, where we know enough to come up with some compelling and seductive explanations.Homo Mysterious is a guide to creative thought and future explorations, based on the best, most current thinking by evolutionary scientists. It captures the allure of the not-yet-known for those interested in stretching their scientific imaginations.

    Prusiner received a Nobel Prize, the world's most prestigious award for achievement in physiology or medicine. That he was the sole recipient of the award for the year was entirely appropriate, for his struggle to identify the agent responsible for ravaging the brains of animals suffering from scrapie and mad cow disease, and of humans with Creutzfeldt-Jakob disease, had been waged largely alone and in some cases in the face of strenuous disagreement.   In this book, Prusiner tells the remarkable story of his discovery of prions—infectious proteins that replicate and cause disease but surprisingly contain no genetic material—and reveals how superb and meticulous science is actually practiced using talented teams of researchers who persevere. He recounts the frustrations and rewards of years of research and offers fascinating portraits of his peers as they raced to discover the causes of fatal brain diseases. Prusiner’s hypothesis, once considered heresy, now stands as accepted science and the basis for developing diagnoses and eventual cures. He closes with a meditation on the legacy of his discovery: What will it take to cure Alzheimer’s, Parkinson’s, Lou Gehrig’s and other devastating diseases of the brain?

    They even became friends over the years, but they parted ways when it came to psychology. While Freud's approach was clinical and scientific in the Western sense, Jung started to draw his inspiration from Eastern philosophies and religions. Because of Carl Jung we have today a bridge between the mythological and mysterious world and the world of psychology. His research into dreams and sub-conscious parts of the minds offers riveting insights into human psychology that none before him have been able to. While Freudian psychology is still the branch most taught within universities, there is a large undercurrent of Jungian psychology seeping into our society. Especially the spiritualists and the New Age movement have embraced Jung as a teacher to better understand their own "Shadows" and dark aspects of the psyche. In this short read you will be given a concise and insightful introduction into the world and psychology of Carl Jung.

    With plenty of engaging material, practice questions, and practical ideas, this updated edition contains everything your students need to succeed in Cambridge IGCSE biology.

    Each clique of scientists has a part of the story correct, but new evidence shows they are all fundamentally wrong.On the one side, we have academics highlighting the astonishing fossil record of China with multiple sites now producing modern human fossils aged between 80 - 120 thousand years, or older. Several extremely ancient fossil finds in China, including Dali, Maba and Jinniushan, place archaic Homo sapiens in this region up to 260,000 years ago.On the other side, we have scientists pointing to Africa's impressive fossil record with its evidence of potential ancestors going back around 6 million years. The evidence of extreme genetic diversity among Africans and the discovery of 300,000-year-old archaic Homo sapiens fossils in Morocco tends to further support the idea that humans came out from Africa. We can understand why both sides are so sure of their positions, and why the debate continues. While leading academics focussed on their own agendas, they overlooked significant evidence. Between the two poles of Out of Africa and Out of Asia Theory, exists a 'Middle Way'. The Forgotten Exodus: The Into Africa Theory of Human Evolution, reveals that within the known fossil record, the current genetic studies and recent paleoclimate models there is compelling evidence for a superior theory of human origins, representing a paradigm displacement.The Into Africa Theory does not dispute the evidence placing the earliest hominins in Africa.However, it does not agree with the consensus view that Homo sapiens emerged there first and later migrated to Eurasia.The Into Africa Theory recognises the extraordinary evidence for critical stages in our development occurring in East and Southeast Asia. It is abundantly clear that as a new concerted effort to gather and evaluate fossil evidence begins in earnest we see astonishing new discoveries. The Into Africa Theorydisputes the claims of Out of Africa and Out of Asia(or Europe) adherents over the starting point for the migration which populated Eurasia approximately 60,000 years ago and identifies the actual location.Amazing facts that you will encounter:-Homo heidelbergensis was not ancestral to modern humans -Denisovan fossils in Siberia carried DNAfrom Australian Aboriginals-An Indonesian supervolcano brought about the end for multiple hominin species-Climate catastrophe locked humans in Africa from 73,000 to 59,000 years ago-There is no African fossil DNA over 10,000 years in age-While supposedly isolated, Aboriginal Australians interbred with Denisovans 44,000 years agoYou will gain access to a long-forgotten conversation involving the famous evolutionary scientists Allan Wilson and Rebecca Cann, in which they admitted that their data suggested Aboriginal Australians were ancestral to all modern humans.Learn why the appearance of the haplogroups foundational to Eurasians, L3 and CT, had to come from a population incursion rather than an in-situ mutation.Explore the cutting-edge scientific findings of 2016 and 2017 alongside a broad range of anomalies long suppressed or ignored in academic circles.The Forgotten Exodus' author Bruce R. Fenton began his journey towards a new understanding of human origins after an expedition to a mysterious megalithic complex in the Ecuadorian Amazon. The Information Systems professional and lifelong scholar of ancient cultures, found himself tracing the threads of the human story across six continents and through 6,000,000 years of history. You will come away with a unique view of humanity and a sense of excitement for revelations still set to arrive. This book reminds all of us that we have a collective ability to overcome enormous obstacles.

    It is one of many awe-inspiring, magical processes that have evolved among the fungi, yet this group remains the least studied and most poorly understood kingdom of organisms. In Mushroom, NicholasMoney offers a vibrant introduction to the world of mushrooms, investigating the science behind these organisms as well as their enduring cultural and imaginative appeal. Beginning with the basics of mushroom biology, Money leads us through a history of mushroom research, painting portraits of thecolorful characters involved in their study--among them, Beatrix Potter, the celebrated author and creator of Peter Rabbit, and Captain Charles McIlvaine, a Civil War veteran who engaged in a dangerous quest to determine the edibility of every mushroom in North America. Money also discusses the usesof mushrooms today, exploring their importance as food and medicine, their use as recreational drugs, and as the cause of horrific poisonings. A cultural, natural, and scientific history in one, Mushroom is a must-read for mycophiles, mushroom gatherers, and nature lovers alike.

    All animals, human or otherwise, thrive when they mimic key elements of life in their natural habitat. From diet to movement to sleep, this evolutionary perspective sheds light on some of our most pressing health concerns. What is causing the rise of chronic conditions, such as obesity, diabetes, and depression? Is eating red meat going to kill you? Is avoiding the sun actually the best way to avoid skin cancer? Durant takes readers on a thrilling ride to the Paleolithic and beyond, unlocking the health secrets of our ancient ancestors. What do obese gorillas teach us about weight loss? How can Paleolithic skulls contain beautiful sets of teeth? Why is the Bible so obsessed with hygiene? What do NASA astronauts teach us about getting a good night’s sleep? And how are Silicon Valley techies hacking the human body? Blending science and culture, anthropology and philosophy, John Durant distills the lessons from his adventures and shows how to apply them to day-to-day life, teaching people how to construct their own personal “habitat” that will enable them to thrive. The book doesn’t just address what we eat, but why we eat it; not just how to exercise, but the purpose of functional movement; not just being healthy, but leading a purposeful life. Combining the best of ancient wisdom with cutting edge science, Durant crafts a vision of health that is both fresh and futuristic.

    Today, more than sixty years later, members of a new generation of scientists are attempting to create life from the ground up. Science has moved forward in leaps and bounds since Schrodinger's time, but our understanding of what does and does not constitute life has only grown more complex. An era that has already seen computer chip-implanted human brains, genetically engineered organisms, genetically modified foods, cloned mammals, and brain-dead humans kept alive by machines is one that demands fresh thinking about the concept of life. While a segment of our national debate remains stubbornly mired in moral quandaries over abortion, euthanasia, and other right to life issues, the science writer Ed Regis demonstrates how science can and does provide us with a detailed understanding of the nature of life. Written in a lively and accessible style, and synthesizing a wide range of contemporary research, What Is Life? is a brief and illuminating contribution to an age-old debate.

    But aging does not have to mean decline. World-renowned surgeon Dr. Steven Gundry has been treating mature patients for most of his career. He knows that everyone thinks they want to live forever, until they hit middle age and witness the suffering of their parents and even their peers. So how do we solve the paradox of wanting to live to a ripe old age—but enjoy the benefits of youth?This groundbreaking book holds the answer. Working with thousands of patients, Dr. Gundry has discovered that the “diseases of aging” we most fear are not simply a function of age; rather, they are a byproduct of the way we have lived over the decades. In The Longevity Paradox, he maps out a new approach to aging well—one that is based on supporting the health of the “oldest” parts of us: the microorganisms that live within our bodies.Our gut bugs—the bacteria that make up the microbiome—largely determine our health over the years. From diseases like cancer and Alzheimer’s to common ailments like arthritis to our weight and the appearance of our skin, these bugs are in the driver’s seat, controlling our quality of life as we age.The good news is, it’s never too late to support these microbes and give them what they need to help them—and you—thrive. In The Longevity Paradox, Dr. Gundry outlines a nutrition and lifestyle plan to support gut health and live well for decades to come. A progressive take on the new science of aging, The Longevity Paradox offers an action plan to prevent and reverse disease as well as simple hacks to help anyone look and feel younger and more vital.