Kasser launches an ambitious and exciting inquiry into what makes science science, using the tools of philosophy to ask: * Why is science so successful? * Is there such a thing as the scientific method? * How do we distinguish science from pseudoscience? * Is science rational, cumulative, and progressive? Focusing his investigation on the vigorous debate over the nature of science that unfolded during the past 100 years, Professor Kasser covers important philosophers such as Karl Popper, W. V. Quine, Thomas Kuhn, Paul Feyerabend, Imre Lakatos, Carl Hempel, Nelson Goodman, and Bas van Fraassen.All of these thinkers responded in one way or another to logical positivism, the dominant movement influencing the philosophy of science during the first half of the 20 th century. Logical positivism attempted to ground science exclusively in what could be known through direct experience and logic.It sounds reasonable, but logical positivism proved to be riddled with serious problems, and its eventual demise is an object lesson in how truly difficult it is—perhaps impossible—to secure the logical foundations of a subject that seems so unassailably logical: science.

    

    He shows how oxygen underpins the origin of biological complexity, the birth of photosynthesis, the sudden evolution of animals, the need for two sexes, the accelerated aging of cloned animals like Dolly the sheep, and the surprisingly long lives of bats and birds. Drawing on this grand evolutionary canvas, Oxygen offers fresh perspectives on our own lives and deaths, explaining modern killer diseases, why we age, and what we can do about it. Advancing revelatory new ideas, following chains of evidence, the book ranges through many disciplines, from environmental sciences to molecular medicine. The result is a captivating vision of contemporary science and a humane synthesis of our place in nature. This remarkable book will redefine the way we think about the world.

    While it’seasy to see that stress affects health and well-being, or that your blood pressure rises when you’re angry, cutting-edge research shows that the mind-body connection goes much further.Numerous studies on the brain’s interaction with the body demonstrate that health is directly affected by our social environments, socioeconomic status, culture, behaviors, relationships, psychological states, and habits of mind, among many factors. Current mind-body science reveals facts such as these: As few as eight weeks of mindfulness meditation can meaningfully boost your immune system. Extreme stress and low social support increase the risk of breast cancer by a factor of 9. Contact with nature is correlated with numerous positive health outcomes, including improved attention for children, reduced stress, and enhanced work performance. Chronic hostility portends calcification of the coronary arteries, even in young people. Expressive writing by patients is correlated with improved outcomes for both asthma and rheumatoid arthritis.Mind-body medicine—working in tandem with traditional medical practice—makes use of a large spectrum of psychological, physical, and behavioral treatments, drawn from many disciplines, in an approach to health care that aims to treat the whole person. It provides highly effective resources for preventing and treating a wide range of medical conditions, such as cardiovascular disease, stress, cancer, and depression—as well as for fostering the ultimate goals of health care: truly optimal and lasting physical health, and emotional and psychological well-being.A knowledge of this exciting field offers you critical understanding of the state of the art of health care and a significant new direction in medicine. But beyond valuable knowledge, a grounding in mind-body medicine gives you numerous practical, empowering tools for your own health care, as well as that of your family—tools that can make a profound difference for healthful, vibrant living.In Mind-Body Medicine: The New Science of Optimal Health, you’ll study this subject in compelling depth, with the expert guidance of Professor Jason M. Satterfield of the University of California, San Francisco. These 36 eye-opening lectures offer you a comprehensive overview of the field, providing rigorous answers to the questions of what makes us sick, what makes us well, and what we can do about it.You’ll look closely at the anatomical and biological systems through which what is “outside” in the environment gets “inside” to affect our minds and bodies. You’ll also examine recent research on subjects ranging from the impact our emotions and psychology have on health to the crucial roles that social, cultural, and behavioral factors play. And you’ll learn about effective mind-body treatments for numerous common medical conditions and diseases.Finally, you’ll finish the course with a toolbox of ideas and interventions for your personal wellness goals, empowering you to partner more effectively with your medical providers and maximize your own health.A Remarkable New Context for Health Care Professor Satterfield, a highly respected professor of clinical medicine and a specialist on the intersection of psychological factors and physical health, brings to the table his deep knowledge of mind-body science and extensive clinical experience in its application.In the course’s opening, he introduces you to the model of “biopsychosocial medicine,” which looks at the relationship between biological, psychological, and social factors in health.In studying how the biopsychosocial model is applied in modern medicine, you delve into these core subject areas:Biological pathways:You first investigate the anatomy and physiology of four biological systems through which the “outside” gets “in.” By reviewing a detailed study of the autonomic nervous system and the neuroendocrine system, discover how the brain activates the body’s two stress-response systems, and how these systems crucially affect health and well-being. Learn also about the physiology of immune function and the effects of stress on immune response and healing. Study the mechanisms of genetics as well as fascinating research indicating that your behavior can alter your genetic material, for better or worse—changes that can be passed on to future generations.Psychological factors in health: In the course of nine lectures, you look in depth at the critical ways in which psychology affects the body. Learn how negative emotional states such as anger and hostility can influence both the onset and progression of disease, and how positive emotions aid substantially in healing and wellness. Study how cognition—the ways in which we think and process our experiences—affects emotional states and behavior. Drawing from cognitive and other behavioral therapies, learn effective techniques for reshaping thinking, emotions, and behavior. Review evidence that certain personality types may be predisposed to conditions such as cardiovascular disease and depression, and learn how we can compensate for risk-carrying personality traits by working with cognitions and emotions. Investigate the neuroscience of behavior and the important effects of our behaviors on both disease and disease prevention. Look at stress as an integration of biological, cognitive, and social factors, and see how we can approach stress response and coping as a developmental skill. Social and ecological factors: You also study the important effects on health of factors such as culture, identity, socioeconomic status, social support, communities, and public health policy. Examine the studied correlations of income to health, education level to longevity, and ethnicity to susceptibility to disease, and consider how we can use this knowledge to benefit both individual and public health. Review research linking social support to health in many medical conditions, such as heart disease, cancer, and pregnancy; and do a detailed assessment to evaluate and strengthen your own social support network. Investigate how spiritual affiliations and practices have distinct physical benefits, such as reducing blood pressure, cortisol, and inflammation; improving lipid profiles and cardiovascular health; and extending life expectancy. Assess how physical environments affect health, how national and local culture impacts health-related behaviors, and how public initiatives can create healthier behaviors, environments, and communities.Tools and Strategies for Optimal WellnessBuilding on the biopsychosocial model, you study mind-body treatments for common conditions such as cardiovascular disease, stress, cancer, obesity, chronic pain, depression, anxiety, and post-traumatic stress disorder.Here, you learn about specific practices and interventions that you can use in your own health care program, such as these. Stress management: For both personal and occupational stress, learn about a spectrum of stress management approaches, from cognitive restructuring and perspective shifting to meditation, breathing techniques, relaxation training, and the learnable skill of resilience. Strategies for successful behavior change: With reference to concerns such as lifestyle change, weight management, and disease prevention, study the leading models of effective behavior change, as well as specific approaches such as the strategies of motivational interviewing, the four key elements of change, and the internal skills of self-regulation. Heart disease—prevention and treatment: Survey psychosocial interventions for heart disease, including a range of behavior change approaches, stress and emotion management, somatic quieting, social connection, and dramatic evidence that cardiac disease can be reversed through lifestyle change. Treatment of pain: Study mind-body factors in pain experience, and learn about treatments including cognitive and behavior change, acupuncture, mindfulness-based stress reduction, and biofeedback. Fatigue, headaches, insomnia: Investigate the variety of medical conditions that show no clear organic cause, such as chronic fatigue, tension headaches, and sleep disorders; and review effective psychological, physical, and behavioral approaches to treatment.Professor Satterfield’s teaching combines an extraordinary breadth of knowledge, clear and accessible explanations of the science involved, and a highly compassionate approach to patient care. He enriches the lectures with stories and case studies of patients in treatment for stress, heart conditions, insomnia, trauma, and other health challenges, showing you what mind-body medicine looks like in clinical practice and how you can integrate its lessons into your health program and daily life.With the knowledge and tools you’ll learn in Mind-Body Medicine: The New Science of Optimal Health, you can begin your own biopsychosocial assessment, identify your strengths and challenges in partnership with your medical providers, and take authentic steps toward your fullest physical and mental wellness.

    The Human Genome Project finished sequencing human DNA. It seemed it was only a matter of time until we had all the answers to the secrets of life on this planet. The cutting-edge of biology, however, is telling us that we still don't even know all of the questions. How is it that, despite each cell in your body carrying exactly the same DNA, you don't have teeth growing out of your eyeballs or toenails on your liver? How is it that identical twins share exactly the same DNA and yet can exhibit dramatic differences in the way that they live and grow? It turns out that cells read the genetic code in DNA more like a script to be interpreted than a mould that replicates the same result each time. This is epigenetics and it's the fastest-moving field in biology today. The Epigenetics Revolution traces the thrilling path this discipline has taken over the last twenty years. Biologist Nessa Carey deftly explains such diverse phenomena as how queen bees and ants control their colonies, why tortoiseshell cats are always female, why some plants need a period of cold before they can flower, why we age, develop disease and become addicted to drugs, and much more. Most excitingly, Carey reveals the amazing possibilities for humankind that epigenetics offers for us all - and in the surprisingly near future.

    

    David Christian, professor of history at San Diego State University, surveys the past at all possible scales, from conventional history, to the much larger scales of biology and geology, to the universal scales of cosmology.

    Whether it's something as minor as a brush with the common cold or as serious as Ebola, we all have grappled with infections and will continue to encounter them as we age.On a worldwide scale, infectious diseases account for 26 percent of all deaths, second only to cardiovascular diseases. And unlike chronic diseases, infectious diseases are unique in their potential for explosive global impacts.Now, in the 24 engaging lectures of Introduction to Infectious Diseases, you can get a comprehensive overview of diseases from the mundane to the fatal from renowned physician and award-winning professor Dr. Barry Fox.Begin with an overview of the microscopic particles responsible for disease: bacteria, fungi, hybrid germs, and viruses. You will see how they invade the body; look through the microscope at pathogens to identify their inner components; follow germs through to different body systems and see what effects they have; and learn why we may be losing the battle against some germs.

    And it has an undeniable power to move us in ways that enrich our lives - provided it is understood.If you have ever longed to appreciate great concert music, to learn its glorious language and share in its sublime pleasures, the way is now open to you, through this series of 48 wonderful lectures designed to make music accessible to everyone who yearns to know it, regardless of prior training or knowledge. It's a lecture series that will enable you to first grasp music's forms, techniques, and terms - the grammatical elements that make you fluent in its language - and then use that newfound fluency to finally hear and understand what the greatest composers in history are actually saying to us.And as you learn the gifts given us by nearly every major composer, you'll come to know there is one we share with each of them - a common humanity that lets us finally understand that these were simply people speaking to us, sharing their passion and wanting desperately to be heard. Using digitally recorded musical passages to illustrate his points, Professor Greenberg will take you inside magnificent compositions by Bach, Handel, Haydn, Mozart, Beethoven, Chopin, Verdi, Wagner, Brahms, Tchaikovsky, Stravinsky, and more. Even if you have listened to many of these illustrative pieces throughout your life - as so many of us have - you will never hear them the same way again after experiencing these lectures.

    But is old age all doom and gloom?Not at all! While it's true that some functions in the aging brain decline, neuroscientists have discovered that many other brain functions remain stable - or even improve - as we age. Furthermore, nurture plays as significant a role as nature, and there are a number of strategies you can implement to stave off declining brain function, including:Incorporating physical activity into your routineEating a healthy dietMaintaining a vibrant social lifeReducing your stressThe science behind the aging brain tells a fascinating - and often counterintuitive - story. Is "aging" a disease or merely a natural occurrence that produces disease-like symptoms? If humans are biologically programmed to survive and thrive, why do we age at all? Is it possible (or even desirable) to "cure" aging altogether?Delve into these questions and more in The Aging Brain. Taught by a neuroscientist and award-winning professor at the University of Michigan, these 12 eye-opening lectures will give you a wealth of new insights into what happens to the brain over time - as well as strategies to mitigate the effects of aging and enhance your quality of life into old age.With a mix of scientific research and practical applications, Professor Polk brings cutting-edge science to life. He takes you down to the cellular and even molecular levels of the brain to show you why certain functions decline, how some aspects of brain aging are under genetic control, and what you can do to prolong your health and keep your mind sharp. Aging affects us all, but you have some control over how it affects you.

    In the mid-1970s, scientists began using DNA sequences to reexamine the history of all life. Perhaps the most startling discovery to come out of this new field—the study of life’s diversity and relatedness at the molecular level—is horizontal gene transfer (HGT), or the movement of genes across species lines. It turns out that HGT has been widespread and important. For instance, we now know that roughly eight percent of the human genome arrived not through traditional inheritance from directly ancestral forms, but sideways by viral infection—a type of HGT.David Quammen chronicles these discoveries through the lives of the researchers who made them—such as Carl Woese, the most important little-known biologist of the twentieth century; Lynn Margulis, the notorious maverick whose wild ideas about “mosaic” creatures proved to be true; and Tsutomu Wantanabe, who discovered that the scourge of antibiotic-resistant bacteria is a direct result of horizontal gene transfer, bringing the deep study of genome histories to bear on a global crisis in public health.

    Relativity and quantum physics touch the very basis of physical reality, altering our commonsense notions of space and time, cause and effect. Both have reputations for complexity. But the basic ideas behind relativity and quantum physics are, in fact, simple and comprehensible by anyone. As Professor Wolfson points out, the essence of relativity can be summed up in a single sentence: The laws of physics are the same for all observers in uniform motion. The same goes for quantum theory, which is based on the principle that the "stuff " of the universe-matter and energy-is not infinitely divisible but comes in discrete chunks called "quanta." Profound ... Beautiful ... Relevant Why should you care about these landmark theories? Because relativity and quantum physics are not only profound and beautiful ideas in their own right, they are also the gateway to understanding many of the latest science stories in the media. These are the stories about time travel, string theory, black holes, space telescopes, particle accelerators, and other cutting-edge developments. Consider these ideas: Although Einstein's theory of general relativity dates from 1914, it has not been possible to test certain predictions until recently. The Hubble Space Telescope is providing some of the most striking confirmations of the theory, including certain evidence for the existence of black holes, objects that warp space and time so that not even light can escape. Also, the expansion of the universe predicted by the theory of general relativity is now a known rate. General relativity also predicts an even weirder phenomenon called "wormholes" that offer shortcuts to remote reaches of time and space. According to Einstein's theory of special relativity, two twins would age at different rates if one left on a high-speed journey to a distant star and then returned. This experiment has actually been done, not with twins, but with an atomic clock flown around the world. Another fascinating experiment confirming that time slows as speed increases comes from measuring muons at the top and bottom of mountains. A seemingly absurd consequence of quantum mechanics, called "quantum tunneling," makes it possible for objects to materialize through impenetrable barriers. Quantum tunneling happens all the time on the subatomic scale and plays an important role in electronic devices and the nuclear processes that keep the sun shining. Some predictions about the expansion of the universe were so odd that Einstein himself tried to rewrite the mathematics in order to eliminate them. When Hubble discovered the expansion of the universe, Einstein called the revisions the biggest mistake he had ever made. An intriguing thought experiment called "Schrödinger's cat" suggests that a cat in an enclosed box is simultaneously alive and dead under experimental conditions involving quantum phenomena. From Aristotle to the Theory of Everything Professor Wolfson begins with a brief overview of theories of physical reality starting with Aristotle and culminating in Newtonian or "classical" physics. Then he outlines the logic that led to Einstein's theory of special relativity, and the simple yet far-reaching insight on which it rests. With that insight in mind, you move on to consider Einstein's theory of general relativity and its interpretation of gravitation in terms of the curvature of space and time. Professor Wolfson then shows how inquiry into matter at the atomic and subatomic scales led to quandaries that are resolved-or at least clarified-by quantum mechanics, a vision of physical reality so at odds with our experience that it nearly defies language. Bringing relativity and quantum mechanics into the same picture leads to hypotheses about the origin, development, and possible futures of the entire universe, and the possibility that physics can produce a "theory of everything" to account for all aspects of the physical world. Fascinating Incidents and Ideas Along the way, you'll explore these fascinating incidents and ideas: In the 1880s, Albert Michelson and Edward Morley conducted an experiment to determine the motion of the Earth relative to the ether, which was a supposedly imponderable substance pervading all of space. You'll learn about their experiment, its shocking result, and the resulting theoretical crisis. In 1905, a young Swiss patent clerk named Albert Einstein resolved the crisis by discarding the ether concept and asserting the principle of relativity-that the laws of physics are the same for all observers in uniform motion. Relativity implies that the time order of events can be different in different reference frames. Does this wreak havoc with cause and effect? And why does Einstein assert that nothing can go faster than light? Shortly after publishing his 1905 paper on special relativity, Einstein realized that his theory required a fundamental equivalence between mass and energy, which he expressed in the equation E=mc2. Among other things, this famous formula means that the energy contained in a single raisin could power a large city for a whole day. Historically, the path to general relativity followed Einstein's attempt to incorporate gravity into relativity theory, which led to his understanding of gravity not as a force, but as a local manifestation of geometry in curved spacetime. Quantum theory places severe limits on our ability to observe nature at the atomic scale because it implies that the act of observation necessarily disturbs the thing that is being observed. The result is Werner Heisenberg's famous "uncertainty principle." Are quarks, the particles that make up protons and neutrons, the truly elementary particles? What are the three fundamental forces that physicists identify as holding particles together? Could they be manifestations of a single, universal force? A Teaching Legend On his own Middlebury College campus, Professor Wolfson is a teaching legend with an infectious enthusiasm for his subject and a knack for conveying difficult concepts in a way that fosters true understanding. He is the author of an introductory text on physics, a contributor to the esteemed publication Scientific American, and a specialist in interpreting science for the nonspecialist. In this course, Professor Wolfson uses extensive illustrations and diagrams to help bring to life the theories and concepts that he discusses. Thus we highly recommend our DVD version, although Professor Wolfson is mindful of our audio students and carefully describes visual materials throughout his lectures. Professor Richard Wolfson on the Second Edition of Einstein's Relativity: "The first version of this course was produced in 1995. In this new version, I have chosen to spend more time on the philosophical interpretation of quantum physics, and on recent experiments relevant to that interpretation. I have also added a final lecture on the theory of everything and its possible implementation through string theory. The graphic presentations for the DVD version have also been extensively revised and enhanced. But the goal remains the same: to present the key ideas of modern physics in a way that makes them clear to the interested layperson."

    Robinson, Ph.D., Oxford UniversityThe Great CoursesPhilosophy & Intellectual HistoryThe Teaching CompanyLecture Series60 lectures, 30 minutes/lecture Taught by Daniel N. Robinson Philosophy Faculty, Oxford University; Distinguished Professor, Emeritus, Georgetown University Ph.D., City University of New York Humanity left childhood and entered the troubled but productive world when it started to criticize its own certainties and weigh the worthiness of its most secure beliefs. Thus began that "Long Debate" on the nature of truth, the scale of real values, the life one should aspire to live, the character of justice, the sources of law, the terms of civic and political life-the good, the better, the best. The debate continues, and one remains aloof to it at a very heavy price, for "the unexamined life is not worth living." This course of 60 lectures gives the student a sure guide and interpreter as the major themes within the Long Debate are presented and considered. The persistent themes are understood as problems: * The problem of knowledge, arising from concerns as to how or whether we come to know anything, and are justified in our belief that this knowledge is valid and sound * The problem of conduct, arising from the recognition that our actions, too, require some sort of justification in light of our moral and ethical sensibilities-or lack of them * The problem of governance, which includes an understanding of sources of law and its binding nature. The great speculators of history have exhausted themselves on these problems and have bequeathed to us a storehouse of insights, some so utterly persuasive as to have shaped thought itself. In these coherent and beautifully articulated lectures you will hear Plato and Aristotle, the Stoics and Epicureans, the Scholastic philosophers and the leaders of Renaissance thought. In addition, you will learn about the architects of the Age of Newton and the Enlightenment that followed in its wake-all this, as well as Romanticism and Continental thought, Nietzsche and Darwin, Freud and William James. This course is a veritable banquet of enriching reflection on mental life and the acts of humanity that proceed from it: the plans and purposes, the values and beliefs, the possibilities and vulnerabilities.

    There are good reasons that language fascinates us so. It not only defines humans as a species, placing us head and shoulders above even the most proficient animal communicators, but it also beguiles us with its endless mysteries. For example: * How did different languages come to be? * Why isn’t there just a single language? * How does a language change, and when it does, is that change indicative of decay or growth? * How does a language become extinct? Dr. John McWhorter, one of America’s leading linguists and a frequent commentator on network television and National Public Radio, addresses these and other questions as he takes you on an in-depth, 36-lecture tour of the development of human language, showing how a single tongue spoken 150,000 years ago has evolved into the estimated 6,000 languages used around the world today.An accomplished scholar, Professor McWhorter is also a skilled popularizer, whose book The Power of Babel was called "startling, provocative, and remarkably entertaining," by the San Diego Union-Tribune.The London Times called him "a born teacher." And Steven Pinker, best known as the author of The Language Instinct, offered this praise for the book: "McWhorter’s arguments are sharply reasoned, refreshingly honest, and thoroughly original."Course Lecture Titles1. What Is Language? 2. When Language Began 3. How Language Changes—Sound Change 4. How Language Changes—Building New Material 5. How Language Changes—Meaning and Order 6. How Language Changes—Many Directions 7. How Language Changes—Modern English 8. Language Families—Indo-European 9. Language Families—Tracing Indo-European 10. Language Families—Diversity of Structures 11. Language Families—Clues to the Past 12. The Case Against the World’s First Language 13. The Case For the World’s First Language 14. Dialects—Subspecies of Species 15. Dialects—Where Do You Draw the Line? 16. Dialects—Two Tongues in One Mouth 17. Dialects—The Standard as Token of the Past 18. Dialects—Spoken Style, Written Style 19. Dialects—The Fallacy of Blackboard Grammar 20. Language Mixture—Words 21. Language Mixture—Grammar 22. Language Mixture—Language Areas 23. Language Develops Beyond the Call of Duty 24. Language Interrupted 25. A New Perspective on the Story of English 26. Does Culture Drive Language Change? 27. Language Starts Over—Pidgins 28. Language Starts Over—Creoles I 29. Language Starts Over—Creoles II 30. Language Starts Over—Signs of the New 31. Language Starts Over—The Creole Continuum 32. What Is Black English? 33. Language Death—The Problem 34. Language Death—Prognosis 35. Artificial Languages 36. Finale—Master Class

    Course Lecture TitlesWhat is Judaism?The Stages of HistoryThe Jewish LibraryThe Emergence of Rabbinic JudaismJewish WorshipPrayer and the SynagogueThe CalendarA Communal Life-CycleIndividual Life-CyclesGod and Man; God and CommunityPhilosophers and MysticsThe Legal Frameworks of JudaismHalakhaCommon Judaismor a Plurality of Judaisms?Judaism and Others