Some of these drugs are truly transformative, offering major improvements in how long patients live or how they feel--but what is often missing from the popular narrative is that, far too often, these new drugs have marginal or minimal benefits. Some are even harmful. In Malignant, hematologist-oncologist Dr. Vinayak K. Prasad writes about the many sobering examples of how patients are too often failed by cancer policy and by how oncology is practiced. Throughout this work, Prasad illuminates deceptive practices which- promote novel cancer therapies long before credible data are available to support such treatment; and- exaggerate the potential benefits of new therapies, many of which cost thousands and in some cases hundreds of thousands of dollars.Prasad then critiques the financial conflicts of interest that pervade the oncology field, the pharmaceutical industry, and the US Food and Drug administration.This is a book about how the actions of human beings--our policies, our standards of evidence, and our drug regulation--incentivize the pursuit of marginal or unproven therapies at lofty and unsustainable prices. Prasad takes us through how cancer trials are conducted, how drugs come to market, and how pricing decisions are made, asking how we can ensure that more cancer drugs deliver both greater benefit and a lower price. Ultimately, Prasad says,- more cancer clinical trials should measure outcomes that actually matter to people with cancer;- patients on those trials should look more like actual global citizens;- we need drug regulators to raise, not perpetually lower, the bar for approval; and- we need unbiased patient advocates and experts.This well-written, opinionated, and engaging book explains what we can do differently to make serious and sustained progress against cancer--and how we can avoid repeating the policy and practice mistakes of the past.

    It’s called autophagy, and when it’s turned on, the complex operation not only can slow down the aging process, it can optimize biological function as a whole, helping to stave off all manner of diseases and affording us the healthy life spans we never thought possible. It’s the body’s ultimate switch to life. So how can we positively activate this switch? How frequently should we fast and for how long? Which foods dial up autophagy or, conversely, turn it down? How much exercise and what types are recommended? What’s the sweet spot between intermittent fasting, protein cycling, and ketogenic eating? Backed by a wealth of scientific data and featuring a gallery of guidelines to follow for lasting results, The Switch decodes the science of autophagy and teaches you how to control it and maximize its profound impact.

    She urges us to reclaim our right to protect the earth and her diverse species. Food democracy, she says, is the new agenda for ecological sustainability and social justice.

    We think we know the answer: cut calories. Eat less. We conclude that fat is a failure of willpower, perhaps supplemented by a quirk of genetics. But, neuroscientist and former "Nature Neuroscience" editor Sandra Aamodt explains why dieting not only doesn't work, but is likely to do more harm than good.When you diet, your brain thinks you're starving and goes into survival mode. People who have gone on extreme diets may never lose their food obsession as a result, even if they go back to eating normally.The long-term failure rate for losing weight by willpower dieting is between 80 and 98%, depending on how you define success. There's no evidence that dieting improves long-term health, while some research suggests that weight cycling, or dieting to lose weight and gaining it back, can be more dangerous than being overweight itself. It's better to be fifty pounds overweight and exercise every day than it is to be at your "target weight" but sedentary. By harnessing her knowledge of brain science and biology, the author successfully stabilized her weight at a healthy level and enjoys a better relationship with food.Combining deep research and brutal candor about her own experience as a weight cycler, Aamodt gives us several clues into the obesity epidemic based on the latest science, including new findings about gut bacteria, why bariatric surgery works (it has more to do with your brain than your stomach), and what a real alternative to dieting and weight cycling might look like.

    A complete guide to the healthiest foods you can eat - and how to cook them!Why get your nutrients from expensive supplements when you can enjoy delicious, nourishing foods instead? From almonds to yucca, readers will find out what nutrients each of the 150 featured foods contains, what form contains the most nutrients, if it's been recommended to combat any diseases, where to find it, how to prepare it, and how much to eat - plus wonderful recipes using these sometimes obscure foods! Indexes by nutrient, by disease, and by food make finding what you need a snap, and the at-a-glance format makes the information as easy to digest as the foods themselves.

    Cheese. Wine. Beer. Coffee. Chocolate. Most people consume fermented foods and drinks every day. For thousands of years, humans have enjoyed the distinctive flavors and nutrition resulting from the transformative power of microscopic bacteria and fungi. Wild Fermentation: The Flavor, Nutrition, and Craft of Live-Culture Foods is the first cookbook to widely explore the culinary magic of fermentation."Fermentation has been an important journey of discovery for me," writes author Sandor Ellix Katz. "I invite you to join me along this effervescent path, well trodden for thousands of years yet largely forgotten in our time and place, bypassed by the superhighway of industrial food production."The flavors of fermentation are compelling and complex, quite literally alive. This book takes readers on a whirlwind trip through the wide world of fermentation, providing readers with basic and delicious recipes-some familiar, others exotic-that are easy to make at home.The book covers vegetable ferments such as sauerkraut, kimchi, and sour pickles; bean ferments including miso, tempeh, dosas, and idli; dairy ferments including yogurt, kefir, and basic cheesemaking (as well as vegan alternatives); sourdough bread-making; other grain fermentations from Cherokee, African, Japanese, and Russian traditions; extremely simple wine- and beer-making (as well as cider-, mead-, and champagne-making) techniques; and vinegar-making. With nearly 100 recipes, this is the most comprehensive and wide-ranging fermentation cookbook ever published.

    Sugar feeds Cancer: diet and supplements can starve tumors? Nutrition makes chemo and radiation more toxic to the tumor while protecting the patient. Nutrition changes underlying causes of cancer, improving outcome for cancer patients regardless of other therapies. Why Beating Cancer with Nutrition is unique: The book was developed after working with over 500 cancer patients and organizing 3 international symposiums on the subject. The information contained in BCN is both scientifically backed with references and clinically proven in the hospital with patients. This information helps cancer patients to improve quality and quantity of life. BCN had been translated into Japanese and Chinese and is being translated into Korean. BCN had become a home study continuing education course for registered nurses. BCN 2001 version will contain a 72-minute audio CD version in response to the requests from tired cancer patients who said they needed and audio version of the book to get started. BCN had sold 110,000 copies in 7 years in print, which is impressive for small publishers. Why Patrick Quillin is Unique: For the past 10 years, Dr. Patrick Quillin has served as the Director of Nutrition for Cancer Treatment Centers of America. He is an internationally respected expert in the area of nutrition and cancer. He has earned his bachelor's, Master's and doctorate degrees in nutrition and is a registered and licensed dietitian ( RD & LD) and Certified Nutrition Specialist (CNS) with the American College of Nutrition.

    Indeed, what began as an initial response of many institutions -- denial and delay -- has now grown into a crime against humanity. The fossil fuel industry is directing the Bush administration's energy and climate policies-payback for helping Bush get elected. But they're not the only ones to blame: the media and environmental activists are unwittingly worsening the crisis. In his new introduction, Gelbspan reveals that the outlook isn't getting better. The climate continues to change with increasing acceleration: hurricanes devastated Florida; rainfall patterns left two million people starving in Kenya; 2004 was the fourth hottest year on record. At the same time, the coal industry was planning to sabotage an effort in the Senate to begin to regulate carbon dioxide. Officials of Switzerland, France, and Canada said last year that, when the Kyoto Protocol takes effect, they intend to take the United States to court under the World Trade Organization, reasoning that the U.S.'s refusal to lower their carbon emissions amounts to an illegal subsidy-a "carbon subsidy"-on its exports. With the reelection of George W. Bush and a Republican-controlled congress, Boiling Point is more imperative than ever. Both a passionate call-to-arms and a thoughtful roadmap for change, Gelbspan reveals what's at stake for our fragile planet.

    Now, a new edition addresses current developments in cancer research and offers more tips on how people living with cancer can fight it and how healthy people can prevent it. The new edition of Anticancer includes: � The latest research on anticancer foods, including new alternatives to sugar and cautions about some that are now on the market � New information about how vitamin D strengthens the immune system � Warnings about common food contaminants that have recently been proven to contribute to cancer progression � A new chapter on mind-body approaches to stress reduction, with recent studies that show how our reactions to stress can interfere with natural defenses and how friendships can support healing in ways never before understood � A groundbreaking study showing that lifestyle modification, as originally proposed in Anticancer, reduces mortality for breast cancer by an astounding 68 percent after completion of treatment � New supporting evidence for the entire Anticancer program

    Based on more than 40 years of clinical research, this illuminating book unravels the mysteries of nutrition and shows how a low-carbohydrate/high protein diet can help prevent cancer, diabetes, heart disease, and obesity, as well as increase strength, endurance, and muscle mass.

    Alessio Fasano presents the groundbreaking roadmap to a gluten-free lifestyle, and how anyone can live better by going gluten-free. For centuries, bread has been known as the “staff of life.” But for millions of Americans affected by gluten-related disorders, consuming gluten, the complex protein found in wheat, rye, and barley, can be hazardous to their health. In a recent poll presented by Scientific American, over 30% of Americans reported wanting to cut down or eliminate gluten from their diets; the gluten-free market is a $6.3 billion industry and continues to expand.Now, in Gluten Freedom, Alessio Fasano, MD, world-renowned expert and founder of Massachusetts General Hospital’s Center for Celiac Research, reveals the latest developments in scientific research and treatment, and the answers they provide for this rapidly expanding audience. This groundbreaking, authoritative guide is an invaluable roadmap for the newly diagnosed, for those already dealing with gluten-related issues, and for anyone who thinks they may have an issue with gluten. Distinguishing scientific fact from myth, Gluten Freedom explains the latest research, diagnostic procedures, and treatment/diet recommendations, helping consumers make the best choices for themselves and their families. Gluten Freedom also discusses important nutritional implications for behavior-related diagnoses such as autism and conditions such as depression, anxiety, and “foggy mind.” Other highlights include: • The differences between celiac disease, gluten sensitivity, and wheat allergy• Current best practices for gluten-related disorders at any age• Practical information on setting up a gluten-free kitchen, reading labels, and staying safe and healthy in a world filled with hidden sources of gluten• The psychological impact of a diagnosis and its effect on a family• Groundbreaking research for prevention and therapy• Reliable and accurate resources for patients, parents, and physicians• And even recipes for an authentic gluten-free Italian dinner from Dr. Fasano’s home kitchen

    Using everyday language and a range of scientific evidence, Professor Yudkin explores the ins and out of sugar, from the different types - is brown sugar really better than white? - to how it is hidden inside our everyday foods, and how it is damaging our health.Brought up-to-date by childhood obesity expert Dr Robert Lustig M.D., his classic exposé on the hidden dangers of sugar is essential reading for anyone interested in their health, the health of their children and the health of modern society.

    Wiley and Bent Formby deliver staggering findings: Americans really are sick from being tired. Diabetes, heart disease, cancer, and depression are rising in our population. We’re literally dying for a good night’s sleep. Our lifestyle wasn’t always this way. It began with the invention of the lightbulb. When we don’t get enough sleep in sync with seasonal light exposure, we fundamentally alter a balance of nature that has been programmed into our physiology since day one. This delicate biological rhythm rules the hormones and neurotransmitters that determine appetite, fertility, and mental and physical health. When we rely on artificial light to extend our day until 11 p.m., midnight, and beyond, we fool our bodies into living in a perpetual state of summer. Anticipating the scarce food supply and forced inactivity of winter, our bodies begin storing fat and slowing metabolism to sustain us through the months of hibernation and hunger that never arrive. Our own survival instinct, honed over millennia, is now killing us. Wiley and Formby also reveal: -That studies from our own government research prove the role of sleeplessness in diabetes, heart disease, cancer, infertility, mental illness, and premature aging -Why the carbohydrate-rich diets recommended by many health professionals are not only ridiculously ineffective but deadly -Why the lifesaving information that can turn things around is one of the best-kept secrets of our day. Lights Out is one wake-up call none of us can afford to miss.

    Jeffrey Bland has been on the cutting edge of Functional Medicine, which seeks to pinpoint and prevent the cause of illness, rather than treat its symptoms. Managing chronic diseases accounts for three quarters of our total healthcare costs, because we're masking these illnesses with pills and temporary treatments, rather than addressing their underlying causes, he argues. Worse, only treating symptoms leads us down the path of further illness.In The Disease Delusion, Dr. Bland explains what Functional Medicine is and what it can do for you. While advances in modern science have nearly doubled our lifespans in only four generations, our quality of life has not reached its full potential. Outlining the reasons why we suffer chronic diseases from asthma and diabetes to obesity, arthritis and cancer to a host of other ailments, Dr. Bland offers achievable, science-based solutions that can alleviate these common conditions and offers a roadmap for a lifetime of wellness.

    And, like most consumers, he often reads the ingredients label -- without a clue as to what most of it means. So when his young daughter asked, "Daddy, what's polysorbate 60?" he was at a loss -- and determined to find out. From the phosphate mines in Idaho to the corn fields in Iowa, from gypsum mines in Oklahoma to the vanilla harvest in Madagascar, Twinkie, Deconstructed is a fascinating, thoroughly researched romp of a narrative that demystifies some of the most common processed food ingredients -- where they come from, how they are made, how they are used -- and why. Beginning at the source (hint: they're often more closely linked to rock and petroleum than any of the four food groups), we follow each Twinkie ingredient through the process of being crushed, baked, fermented, refined, and/or reacted into a totally unrecognizable goo or powder with a strange name -- all for the sake of creating a simple snack cake. An insightful exploration into the food industry, if you've ever wondered what you're eating when you consume foods containing mono- and diglycerides or calcium sulfate (the latter, a food-grade equivalent) this book is for you.