Life remains the only way to make life. Are we still missing a vital ingredient in its creation?      Like Richard Dawkins' The Selfish Gene, which provided a new perspective on how evolution works, Life on the Edge alters our understanding of our world's fundamental dynamics. Bringing together first-hand experience at the cutting edge of science with unparalleled gifts of explanation, Jim Al-Khalili and Johnjoe Macfadden reveal that missing ingredient to be quantum mechanics; the phenomena that lie at the heart of this most mysterious of sciences. Drawing on recent ground-breaking experiments around the world, each chapter in Life on the Edge engages by illustrating one of life's puzzles: How do migrating birds know where to go? How do we really smell the scent of a rose? How do our genes copy themselves with such precision? Life on the Edge accessibly reveals how quantum mechanics can answer these probing questions of the universe. Guiding the reader through the rapidly unfolding discoveries of the last few years, Al-Khalili and McFadden communicate the excitement of the explosive new field of quantum biology and its potentially revolutionary applications, while offering insights into the biggest puzzle of all: what is life? As they brilliantly demonstrate in these groundbreaking pages, life exists on the quantum edge.

    The Human Genome Project finished sequencing human DNA. It seemed it was only a matter of time until we had all the answers to the secrets of life on this planet. The cutting-edge of biology, however, is telling us that we still don't even know all of the questions. How is it that, despite each cell in your body carrying exactly the same DNA, you don't have teeth growing out of your eyeballs or toenails on your liver? How is it that identical twins share exactly the same DNA and yet can exhibit dramatic differences in the way that they live and grow? It turns out that cells read the genetic code in DNA more like a script to be interpreted than a mould that replicates the same result each time. This is epigenetics and it's the fastest-moving field in biology today. The Epigenetics Revolution traces the thrilling path this discipline has taken over the last twenty years. Biologist Nessa Carey deftly explains such diverse phenomena as how queen bees and ants control their colonies, why tortoiseshell cats are always female, why some plants need a period of cold before they can flower, why we age, develop disease and become addicted to drugs, and much more. Most excitingly, Carey reveals the amazing possibilities for humankind that epigenetics offers for us all - and in the surprisingly near future.

    In the great halls of science, dogma holds that Darwin's theory of natural selection explains every branch on the tree of life: which species thrive, which wither away to extinction, and what features each evolves. But can adaptation by natural selection really account for everything we see in nature? Yale University ornithologist Richard Prum--reviving Darwin's own views--thinks not. Deep in tropical jungles around the world are birds with a dizzying array of appearances and mating displays: Club-winged Manakins who sing with their wings, Great Argus Pheasants who dazzle prospective mates with a four-foot-wide cone of feathers covered in golden 3D spheres, Red-capped Manakins who moonwalk. In thirty years of fieldwork, Prum has seen numerous display traits that seem disconnected from, if not outright contrary to, selection for individual survival. To explain this, he dusts off Darwin's long-neglected theory of sexual selection in which the act of choosing a mate for purely aesthetic reasons--for the mere pleasure of it--is an independent engine of evolutionary change. Mate choice can drive ornamental traits from the constraints of adaptive evolution, allowing them to grow ever more elaborate. It also sets the stakes for sexual conflict, in which the sexual autonomy of the female evolves in response to male sexual control. Most crucially, this framework provides important insights into the evolution of human sexuality, particularly the ways in which female preferences have changed male bodies, and even maleness itself, through evolutionary time. The Evolution of Beauty presents a unique scientific vision for how nature's splendor contributes to a more complete understanding of evolution and of ourselves.

    At the time, Watson was only 24, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science's greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions & bitter rivalries. With humility unspoiled by false modesty, Watson relates his & Crick's desperate efforts to beat Linus Pauling to the Holy Grail of life sciences, the identification of the basic building block of life. Never has a scientist been so truthful in capturing in words the flavor of his work.

    In How to Clone a Mammoth, Beth Shapiro, evolutionary biologist and pioneer in "ancient DNA" research, walks readers through the astonishing and controversial process of de-extinction. From deciding which species should be restored, to sequencing their genomes, to anticipating how revived populations might be overseen in the wild, Shapiro vividly explores the extraordinary cutting-edge science that is being used--today--to resurrect the past. Journeying to far-flung Siberian locales in search of ice age bones and delving into her own research--as well as those of fellow experts such as Svante Paabo, George Church, and Craig Venter--Shapiro considers de-extinction's practical benefits and ethical challenges. Would de-extinction change the way we live? Is this really cloning? What are the costs and risks? And what is the ultimate goal?Using DNA collected from remains as a genetic blueprint, scientists aim to engineer extinct traits--traits that evolved by natural selection over thousands of years--into living organisms. But rather than viewing de-extinction as a way to restore one particular species, Shapiro argues that the overarching goal should be the revitalization and stabilization of contemporary ecosystems. For example, elephants with genes modified to express mammoth traits could expand into the Arctic, re-establishing lost productivity to the tundra ecosystem.Looking at the very real and compelling science behind an idea once seen as science fiction, How to Clone a Mammoth demonstrates how de-extinction will redefine conservation's future.

    It's weirder than we are capable of imagining. And we're all in it together: humans, blue whales, rats, birds of paradise, ridiculous numbers of beetles, molluscs the size of a bus, the sexual gladiators of slugs, bdelliod rotifers who haven't had sex for millions of years and creatures called water bears: you can boil them, freeze them and fire them off into space without killing themWe're all part of the animal kingdom, appearing in what Darwin called 'endless forms most beautiful and most wonderful'. In this breathtakingly audacious book Simon Barnes has brought us all together, seeking not what separates us but what unites us. He takes us white-water rafting through the entire animal kingdom in a book that brings in deep layers of arcane knowledge, the works of Darwin and James Joyce, Barnes's own don't-try-this-at-home adventures in the wild, David Attenborough and Sherlock Holmes.

    But what would it look like to study the whole of history, from the big bang through the present day -- and even into the remote future? How would looking at the full span of time change the way we perceive the universe, the earth, and our very existence?These were the questions David Christian set out to answer when he created the field of "Big History," the most exciting new approach to understanding where we have been, where we are, and where we are going. In Origin Story, Christian takes readers on a wild ride through the entire 13.8 billion years we've come to know as "history." By focusing on defining events (thresholds), major trends, and profound questions about our origins, Christian exposes the hidden threads that tie everything together -- from the creation of the planet to the advent of agriculture, nuclear war, and beyond.With stunning insights into the origin of the universe, the beginning of life, the emergence of humans, and what the future might bring, Origin Story boldly reframes our place in the cosmos.

    Humans have "subdued 75 per cent of the land surface, concocted a wizardry of industrial and medical marvels, strung lights all across the darkness." We now collect the DNA of vanishing species in a "frozen ark," equip orangutans with iPads, create wearable technologies and synthetic species that might one day outsmart us. With her distinctive gift for making scientific discovery intelligible to the layperson, Ackerman takes us on an exciting journey to understand this bewildering new reality, introducing us to many of the people and ideas now creating--perhaps saving--the future.The Human Ageis a surprising, optimistic engagement with the dramatic transformations that have shaped, and continue to alter, our world, our relationship with nature and our prospects for the future.

    The alimentary canal is classic Mary Roach terrain: the questions explored in Gulp are as taboo, in their way, as the cadavers in Stiff and every bit as surreal as the universe of zero gravity explored in Packing for Mars. Why is crunchy food so appealing? Why is it so hard to find words for flavors and smells? Why doesn’t the stomach digest itself? How much can you eat before your stomach bursts? Can constipation kill you? Did it kill Elvis? In Gulp we meet scientists who tackle the questions no one else thinks of—or has the courage to ask. We go on location to a pet-food taste-test lab, a fecal transplant, and into a live stomach to observe the fate of a meal. With Roach at our side, we travel the world, meeting murderers and mad scientists, Eskimos and exorcists (who have occasionally administered holy water rectally), rabbis and terrorists—who, it turns out, for practical reasons do not conceal bombs in their digestive tracts.Like all of Roach’s books, Gulp is as much about human beings as it is about human bodies.

    Will temperatures rise by 2�C or 8�C over the next hundred years? Will sea levels rise by 2 or 30 feet? The only way that we can accurately answer questions like these is by looking into the distant past, for a comparison with the world long before the rise of mankind.We may currently believe that atmospheric shifts, like global warming, result from our impact on the planet, but the earth's atmosphere has been dramatically shifting since its creation. This book reveals the crucial role that plants have played in determining atmospheric change - and hence the conditions on the planet we know today. Along the way a number of fascinating puzzles arise: Why did plants evolve leaves? When and how did forests once grow on Antarctica? How did prehistoric insects manage to grow so large? The answers show the extraordinary amount plants can tell us about the history of the planet -- something that has often been overlooked amongst the preoccuputations with dinosaur bones and animal fossils.David Beerling's surprising conclusions are teased out from various lines of scientific enquiry, with evidence being brought to bear from fossil plants and animals, computer models of the atmosphere, and experimental studies. Intimately bound up with the narrative describing the dynamic evolution of climate and life through Earth's history, we find Victorian fossil hunters, intrepid polar explorers and pioneering chemists, alongside wallowing hippos, belching volcanoes, and restless landmasses.

    How they got here, persevered, and ultimately thrived is a story that resonates from the Pleistocene to our modern era. The lower sea levels of the Ice Age exposed a vast land bridge between Asia and North America, but the land bridge was not the only way across. Different people arrived from different directions, and not all at the same time.The first explorers of the New World were few, their encampments fleeting. The continent they reached had no people but was inhabited by megafauna--mastodons, giant bears, mammoths, saber-toothed cats, five-hundred-pound panthers, enormous bison, and sloths that stood one story tall. The first people were hunters--Paleolithic spear points are still encrusted with the proteins of their prey--but they were wildly outnumbered and many would themselves have been prey to the much larger animals.Atlas of a Lost World chronicles the last millennia of the Ice Age, the violent oscillations and retreat of glaciers, the clues and traces that document the first encounters of early humans, and the animals whose presence governed the humans' chances for survival. A blend of science and personal narrative reveals how much has changed since the time of mammoth hunters, and how little. Across unexplored landscapes yet to be peopled, readers will see the Ice Age, and their own age, in a whole new light.

    Why do living things and physical phenomena take the forms they do? Analyzing the mathematical and physical aspects of biological processes, this historic work, first published in 1917, has become renowned as well for the poetry of is descriptions.

    It was five feet long, with steel-blue scales, luminescent eyes and remarkable limb-like fins, unlike those of any fish she had ever seen. Determined to preserve her unusual find, she searched for days for a way to save it, but ended up with only the skin and a few bones.A charismatic amateur ichthyologist, J.L.B. Smith, saw a thumbnail sketch of the fish and was thunderstruck. He recognized it as a coelacanth (pronounced see-la-kanth), a creature known from fossils dating back 400 million years and thought to have died out with the dinosaurs. With its extraordinary limbs, the coelacanth was believed to be the first fish to crawl from the sea and evolve into reptiles, mammals and eventually mankind. The discovery was immediately dubbed the "greatest scientific find of the century." Smith devoted his life to the search for a complete specimen, afourteen-year odyssey that culminated in a dramatic act of international piracy. As the fame of the coelacanth spread, so did rumors and obsessions. Nations fought over it, multimillion-dollar expeditions were launched, and submarines hand-built to find it. In 1998, the rumors and the truth came together in a gripping climax, which brought the coelacanth back into the international limelight.A Fish Caught in Time is the entrancing story of the most rare and precious fish in the world--our own great uncle forty million times removed.

    Lavishly illustrated with over sixty original artworks, All Yesterdays aims to challenge our notions of how prehistoric animals looked and behaved. As a critical exploration of palaeontological art, All Yesterdays asks questions about what is probable, what is possible, and what is commonly ignored.Written by palaeozoologist Darren Naish, and palaeontological artists John Conway and C.M. Kosemen, All Yesterdays is scientifically rigorous and artistically imaginative in its approach to fossils of the past - and those of the future.

    The effects of homeopathy don’t go away under rigorous scientific conditions. The laws of nature aren’t what they used to be. Thirty years on, no one has an explanation for a seemingly intelligent signal received from outer space. The US Department of Energy is re-examining cold fusion because the experimental evidence seems too solid to ignore. The placebo effect is put to work in medicine while doctors can’t agree whether it even exists.In an age when science is supposed to be king, scientists are beset by experimental results they simply can’t explain. But, if the past is anything to go by, these anomalies contain the seeds of future revolutions. While taking readers on an entertaining tour d’horizon of the strangest of scientific findings – involving everything from our lack of free will to Martian methane that offers new evidence of life on the planet – Michael Brooks argues that the things we don’t understand are the key to what we are about to discover.This mind-boggling but entirely accessible survey of the outer limits of human knowledge is based on a short article by Michael Brooks for New Scientist magazine. It became the sixth most circulated story on the internet in 2005, and provoked widespread comment and compliments (Google “13 things that do not make sense” to see).Michael Brooks has now dug deeply into those mysteries, with extraordinary results.