Since then, we have sequenced the full genomes of a number of mankind's primate relatives at a remarkable rate. The genomes of the common chimpanzee(2005) and bonobo (2012), orangutan (2011), gorilla (2012), and macaque monkey (2007) have already been identified, and the determination of other primate genomes is well underway. Researchers are beginning to unravel our full genomic history, comparing it with closely related species to answerage-old questions about how and when we evolved. For the first time, we are finding our own ancestors in our genome and are thereby gleaning new information about our evolutionary past.In Ancestors in Our Genome, molecular anthropologist Eugene E. Harris presents us with a complete and up-to-date account of the evolution of the human genome and our species. Written from the perspective of population genetics, and in simple terms, the book traces human origins back to their sourceamong our earliest human ancestors, and explains many of the most intriguing questions that genome scientists are currently working to answer. For example, what does the high level of discordance among the gene trees of humans and the African great apes tell us about our respective separations fromour common ancestor? Was our separation from the apes fast or slow, and when and why did it occur? Where, when, and how did our modern species evolve? How do we search across genomes to find the genomic underpinnings of our large and complex brains and language abilities? How can we find the genomicbases for life at high altitudes, for lactose tolerance, resistance to disease, and for our different skin pigmentations? How and when did we interbreed with Neandertals and the recently discovered ancient Denisovans of Asia? Harris draws upon extensive experience researching primate evolution inorder to deliver a lively and thorough history of human evolution. Ancestors in Our Genome is the most complete discussion of our current understanding of the human genome available.

    In this book you will see how commonly performed operations can be found to be useless or even harmful when properly evaluated. That these claims come from an experienced, practicing orthopedic surgeon who performs many of these operations himself, makes the unsettling argument particularly compelling. Of course no surgeon is recommending invasive surgery in bad faith, but Ian Harris argues that the evidence for the success for many common operations, including knee arthroscopies, back fusion or cardiac stenting, become current accepted practice without full examination of the evidence.

    Scientists around the world are currently monitoring the sixth extinction, predicted to be the most devastating extinction event since the asteroid impact that wiped out the dinosaurs. This time around, the cataclysm is us. In prose that is at once frank, entertaining, and deeply informed, The New Yorker writer Elizabeth Kolbert tells us why and how human beings have altered life on the planet in a way no species has before. Interweaving research in half a dozen disciplines, descriptions of the fascinating species that have already been lost, and the history of extinction as a concept, Kolbert provides a moving and comprehensive account of the disappearances occurring before our very eyes. She shows that the sixth extinction is likely to be mankind's most lasting legacy, compelling us to rethink the fundamental question of what it means to be human.

    But, Alex Bellos says, "math can be inspiring and brilliantly creative. Mathematical thought is one of the great achievements of the human race, and arguably the foundation of all human progress. The world of mathematics is a remarkable place."Bellos has traveled all around the globe and has plunged into history to uncover fascinating stories of mathematical achievement, from the breakthroughs of Euclid, the greatest mathematician of all time, to the creations of the Zen master of origami, one of the hottest areas of mathematical work today. Taking us into the wilds of the Amazon, he tells the story of a tribe there who can count only to five and reports on the latest findings about the math instinct--including the revelation that ants can actually count how many steps they've taken. Journeying to the Bay of Bengal, he interviews a Hindu sage about the brilliant mathematical insights of the Buddha, while in Japan he visits the godfather of Sudoku and introduces the brainteasing delights of mathematical games.Exploring the mysteries of randomness, he explains why it is impossible for our iPods to truly randomly select songs. In probing the many intrigues of that most beloved of numbers, pi, he visits with two brothers so obsessed with the elusive number that they built a supercomputer in their Manhattan apartment to study it. Throughout, the journey is enhanced with a wealth of intriguing illustrations, such as of the clever puzzles known as tangrams and the crochet creation of an American math professor who suddenly realized one day that she could knit a representation of higher dimensional space that no one had been able to visualize. Whether writing about how algebra solved Swedish traffic problems, visiting the Mental Calculation World Cup to disclose the secrets of lightning calculation, or exploring the links between pineapples and beautiful teeth, Bellos is a wonderfully engaging guide who never fails to delight even as he edifies. "Here's Looking at Euclid "is a rare gem that brings the beauty of math to life.

    Building a house would entail no more work than planting a seed in the ground. These scenarios may seem far-fetched, but pioneering geneticist George Church and science writer Ed Regis show that synthetic biology is bringing us ever closer to making such visions a reality. In Regenesis, Church and Regis explore the possibilities—and perils—of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. Until now, nature has been the exclusive arbiter of life, death, and evolution; with synthetic biology, we now have the potential to write our own biological future. Indeed, as Church and Regis show, it even enables us to revisit crucial points in the evolution of life and, through synthetic biological techniques, choose different paths from those nature originally took. Such exploits will involve far more than just microbial tinkering. Full-blown genomic engineering will make possible incredible feats, from resurrecting woolly mammoths and other extinct organisms to creating mirror life forms with a molecular structure the opposite of our own. These technologies—far from the out-of-control nightmare depicted in science fiction—have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span. A breathtaking look at the potential of this world-changing technology, Regenesis is nothing less than a guide to the future of life.

    But is it? In this provocative, groundbreaking book, renowned anthropologist (and mother) Sarah Blaffer Hrdy shares a radical new vision of motherhood and its crucial role in human evolution.Hrdy strips away stereotypes and gender-biased myths to demonstrate that traditional views of maternal behavior are essentially wishful thinking codified as objective observation. As Hrdy argues, far from being "selfless," successful primate mothers have always combined nurturing with ambition, mother love with sexual love, ambivalence with devotion. In fact all mothers, in the struggle to guarantee both their own survival and that of their offspring, deal nimbly with competing demands and conflicting strategies.In her nuanced, stunningly original interpretation of the relationships between mothers and fathers, mothers and babies, and mothers and their social groups, Hrdy offers not only a revolutionary new meaning to motherhood but an important new understanding of human evolution. Written with grace and clarity, suffused with the wisdom of a long and distinguished career, Mother Nature is a profound contribution to our understanding of who we are as a species--and why we have become this way.

    These personal tragedies will, and must, be told and heard. There is, however, also a truthful and objective scientific narrative to be written about how the virus played out and how the world set about dealing with it. Spike is that story - from the inside. Its author, Jeremy Farrar, is one of the UK's leading scientists and a ­­member of the SAGE emergency committee.As head of the Wellcome Trust, and an expert in emerging infectious diseases, Jeremy Farrar was one of the first people in the world to hear about a mysterious new respiratory disease in China - and to learn that it could readily spread between people. Farrar describes how it feels as one of the key scientists at the sharp end of a fast-moving situation, when complex decisions must be made quickly amid great uncertainty. His book casts light on the UK government's claims to be 'following the science' in its response to the virus, and is informed not just by Farrar's views but by interviews with other top scientists and political figures.Farrar, who has spent his career on the frontlines of epidemics including Nipah virus in Malaysia, bird flu in Vietnam and Ebola in West Africa, also reflects on the wider issues of Covid-19: the breath-taking scientific advances in creating tests, treatments and vaccines; the challenge to world leaders to respond for the global good and the need to address inequalities that hold back success against the virus. All these shape how the world ultimately fares not just against Covid-19, but against all the major he­­alth challenges we face globally.

    The universe is all about extremes, and in this engaging and thought-provoking book, astronomer Bryan Gaensler gives a whirlwind tour of the galaxies, with an emphasis on its fastest, hottest, heaviest, brightest, oldest, densest, and even loudest elements. From supernova explosions a billion times brighter than the sun to an asteroid the size of a beach ball, Extreme Cosmos offers a fascinating, fresh, and informed perspective of the remarkable richness of the universe, and the incredible physics that modern astronomy has revealed.

    But how the mind works remains one of humankind's greatest mysteries. With boundless curiosity and enthusiasm, Shannon Moffett, a Stanford medical student, takes us down the halls of neuroscience to the front lines of cutting-edge research and medicine to meet some of today's most extraordinary scientists and thinkers, all grappling with provocative questions: Why do we dream? How does memory work? How do we see? What happens when we think? Each chapter delves into a different aspect of the brain, following the experts as they chart new ground. Moffett takes us to a lab where fMRI scans reveal the multitude of stimuli that our brains unconsciously take in; inside an operating room where a neurosurgeon removes a bullet from a patient's skull; to the lab of Christof Koch, a neuroscientist tracking individual neurons in order to crack the code of consciousness; and to a research lab where scientists are investigating the relationship between dreams and waking life. She also takes us beyond the scientific world—to a Zen monk's zendo, where she explores the effects of meditation on the brain; inside the home of a woman suffering from dissociative identity disorder; to a conference with the philosopher Daniel Dennett, who uses illusions, magic, tricks, and logic to challenge our assumptions about the mind; and to the home of the late Nobel Laureate Francis Crick, co-discoverer with James Watson of DNA's double-helix structure. Filled with fascinating case studies and featuring a timeline that tracks the development of the brain from conception to death, The Three Pound Enigma is a remarkable exploration of what it means to be human.

    S. Ramachandran is at the forefront of his field-so much so that Richard Dawkins dubbed him the "Marco Polo of neuroscience." Now, in a major new work, Ramachandran sets his sights on the mystery of human uniqueness. Taking us to the frontiers of neurology, he reveals what baffling and extreme case studies can teach us about normal brain function and how it evolved. Synesthesia becomes a window into the brain mechanisms that make some of us more creative than others. And autism--for which Ramachandran opens a new direction for treatment--gives us a glimpse of the aspect of being human that we understand least: self-awareness. Ramachandran tackles the most exciting and controversial topics in neurology with a storyteller's eye for compelling case studies and a researcher's flair for new approaches to age-old questions. Tracing the strange links between neurology and behavior, this book unveils a wealth of clues into the deepest mysteries of the human brain.

    People need cheering up. I have the answer. ‘Pills, Thrills and Methadone Spills: Adventures of a Community Pharmacist’ is a collection of the best blogs, tweets and anecdotes about the wonderful world of pharmacy.“If the shutter is three quarters down, then we are shut and not just vertically challenged”...“Gave me huge insight into the ‘real’ world of community pharmacy – I didn’t realise just how much pharmacists deal with on a day to day basis, so for me this was very informative, but in a reallyclever, and massively funny way!” Lucy Pitt, Marketing Manager, The Pharmacy Show“As well as being brilliantly funny, this book is a refreshingly honest view of the world of pharmacy. From student pharmacists to the fully-qualified, every chapter provides a story that the reader can relate to and enjoy.” Georgia Salter, Pharmacy Student“A well observed reflection of life in pharmacy with very funny reflections” Catherine Duggan, Royal Pharmaceutical Society"It is always fun to be reminded that pharmacists' perils and fun at the workplace are similar irrespective of which country we practise in!" Selina Hui-Hoong Wee , Pharmacist, Malaysia“A great entertaining and amusing read" Mike Holden, Chief Executive, National Pharmacy AsociationThanks to Laura Martins for her initial book cover design!

    It develops an understanding of function and evolution into the discussion of anatomy of the various systems.

    But more than this, there was gravity. After that, all hell broke loose… In A Universe from Nothing, Krauss revealed how our entire universe could arise from nothing. Now, he reveals what that something—reality—is. And, reality is not what we think or sense—it’s weird, wild, and counterintuitive; it’s hidden beneath everyday experience; and its inner workings seem even stranger than the idea that something can come from nothing. In a landmark, unprecedented work of scientific history, Krauss leads us to the furthest reaches of space and time, to scales so small they are invisible to microscopes, to the birth and rebirth of light, and into the natural forces that govern our existence. His unique blend of rigorous research and engaging storytelling invites us into the lives and minds of the remarkable, creative scientists who have helped to unravel the unexpected fabric of reality—with reason rather than superstition and dogma. Krauss has himself been an active participant in this effort, and he knows many of them well. The Greatest Story challenges us to re-envision ourselves and our place within the universe, as it appears that “God” does play dice with the universe. In the incisive style of his scintillating essays for The New Yorker, Krauss celebrates the greatest intellectual adventure ever undertaken—to understand why we are here in a universe where fact is stranger than fiction.

    An unprecedented blend of science and art, Daniel Levitin's debut, This Is Your Brain on Music, delighted readers with an exuberant guide to the neural impulses behind those songs that make our heart swell. Now he showcases his daring theory of "six songs," illuminating how the brain evolved to play and listen to music in six fundamental forms—for knowledge, friendship, religion, joy, comfort, and love. Preserving the emotional history of our lives and of our species, from its very beginning music was also allied to dance, as the structure of the brain confirms; developing this neurological observation, Levitin shows how music and dance enabled the social bonding and friendship necessary for human culture and society to evolve. Blending cutting-edge scientific findings with his own sometimes hilarious experiences as a musician and music-industry professional, Levitin's sweeping study also incorporates wisdom gleaned from interviews with icons ranging from Sting and Paul Simon to Joni Mitchell, and David Byrne, along with classical musicians and conductors, historians, anthropologists, and evolutionary biologists. The result is a brilliant revelation of the prehistoric yet elegant systems at play when we sing and dance at a wedding or cheer at a concert—or tune out quietly with an iPod.

    It opens with a question: How would an alien scientist view our species? What would it make of our sex differences, our sexual behavior, our child-rearing patterns, our moral codes, our religions, languages, and science? The book tackles these issues by drawing on ideas from two major schools of thought: evolutionary psychology and cultural evolutionary theory. The guiding assumption is that humans are animals, and that like all animals, we evolved to pass on our genes. At some point, however, we also evolved the capacity for culture - and from that moment, culture began evolving in its own right. This transformed us from a mere ape into an ape capable of reshaping the planet, travelling to other worlds, and understanding the vast universe of which we're but a tiny, fleeting fragment.