The format makes learning easy with short, easy-to-read chapters, color tables, key point summaries, and review questions in every chapter. You'll get the latest coverage on regulatory T cells, biology of the Th17 subset of CD4+ T cells, and more. The full-color artwork, comprehensive glossary, and clinical cases are just some of the features that reinforce and test your understanding of how the immune system functions. Student Consult online access lets you search the full text online and pursue further study through integration links. Covers the most up-to-date immunology information including regulatory T cells, and biology of the Th17 subset of CD4+ T cells to keep you completely current. Features integration links through included STUDENT CONSULT access for more in-depth study. Relates basic science to clinical disorders through clinical cases for better application in a real-world setting. Provides a full Glossary to keep you on the cutting edge of immunologic terminology. Includes appendices summarizing the features of CD Molecules, a handy Glossary, and Clinical Cases that test your understanding of how the immune system functions in health and disease. Presents beautiful full-color artwork for enhanced visual learning.

    Like most people, you probably wake up, get hungry for meals and doze off in bed around the same time every day. If you’ve ever experienced jet lag or pulled an all-nighter, you know that this schedule can easily be thrown off kilter. But for some people, that imbalance—difficulty sleeping at night, hunger at odd times, or sudden fatigue at noon—is a constant. If you're one of those people, Dr. Satchin Panda, one of the leading researchers on circadian rhythms, has a plan to reset your body clock.Beginning with an in-depth explanation of the circadian clock—why it’s important, how it works, and how to know it isn’t working—The Circadian Code outlines lifestyle changes to make to get back on track. It's a concrete plan to enhance weight loss, improve sleep, optimize exercise, and manage technology so that it doesn’t interfere with your body’s natural rhythm. Dr. Panda’s life-changing methods show you how to prevent and reverse ailments like diabetes, cancer, and dementia, as well as microbiome conditions like acid reflux, heartburn, and irritable bowel disease.

    In The Beautiful Cure, leading immunologist Professor Daniel Davis describes the scientific quest to understand how it works – and how it is affected by stress, sleep, age and our state of mind – and explains how this knowledge is now unlocking a revolutionary new approach to medicine and well-being.The body's ability to fight disease and heal itself is one of the great mysteries and marvels of nature. But within the last few years painstaking research has resulted in major advances in our understanding of this breathtakingly beautiful inner world: a vast and intricate network of specialist cells, regulatory proteins and dedicated genes that are continually protecting our bodies. Far more powerful than any medicine ever invented, it also plays a crucial role in our daily lives. Already we have found ways to harness these natural defences to create breakthrough drugs and so-called immunotherapies that help us fight cancer, diabetes, arthritis and many age-related diseases, and we are starting to understand whether or not activities such as mindfulness might play a role in enhancing our physical resilience.Written by an expert at the forefront of this adventure, The Beautiful Cure tells a dramatic story of detective work and discovery, of puzzles solved and of the mysteries that remain, of lives sacrificed and saved, introducing the reader to this revelatory new understanding of the human body and what it takes to be healthy.

    Between 1900 and 1907, she infected twenty-two New Yorkers with typhoid fever through her puddings and cakes; one of them died. Tracked down through epidemiological detective work, she was finally apprehended as she hid behind a barricade of trashcans. To protect the public's health, authorities isolated her on Manhattan's North Brother Island, where she died some thirty years later.This book tells the remarkable story of Mary Mallon--the real Typhoid Mary. Combining social history with biography, historian Judith Leavitt re-creates early-twentieth-century New York City, a world of strict class divisions and prejudice against immigrants and women. Leavitt engages the reader with the excitement of the early days of microbiology and brings to life the conflicting perspectives of journalists, public health officials, the law, and Mary Mallon herself.Leavitt's readable account illuminates dilemmas that continue to haunt us. To what degree are we willing to sacrifice individual liberty to protect the public's health? How far should we go in the age of AIDS, drug-resistant tuberculosis, and other diseases? For anyone who is concerned about the threats and quandaries posed by new epidemics, Typhoid Mary is a vivid reminder of the human side of disease and disease control.

    He boarded a friend’s yacht, sailed into the calm blue waters of Long Island Sound, and--poof!--disappeared. He would not be heard from again for five days. What happened during those five days, and in the days and weeks that followed, was so incredible that, even when the truth was finally revealed, many Americans simply would not believe it.The President Is a Sick Man details an extraordinary but almost unknown chapter in American history: Grover Cleveland’s secret cancer surgery and the brazen political cover-up by a politician whose most memorable quote was “Tell the truth.” When an enterprising reporter named E. J. Edwards exposed the secret operation, Cleveland denied it. The public believed the “Honest President,” and Edwards was dismissed as “a disgrace to journalism.” The facts concerning the disappearance of Grover Cleveland that summer were so well concealed that even more than a century later a full and fair account has never been published. Until now.

    In a facility where poverty and social strife are as much a part of the pathology as any microbe, it is the medical students and interns who are thrust into the searing intimacy that is the doctor-patient relationship. With each chapter, Ofri introduces us to a new medical crisis and a human being with an intricate and compelling history.

    He didn’t leave for two and a half months. Watt had developed a rare life-threatening disease that initially baffled doctors. By the time he was allowed home, his ravaged body was forty-six pounds lighter and he was missing most of his small intestine. Watt injects pathos and humor into his medical nightmare, writing about his childhood, reflecting on his family and on his shared life with band member and partner Tracey Thorn. The result is a provocative and affecting memoir about life, illness, and survival.

    alone: Migraine, a disease that is still little understood, yet debilitating to its sufferers. Konnikova takes a clear-eyed look at migraine’s history, diving into current theories and more recent approaches—and offers a deeply personal account of what it’s like to experience migraine, usually with little warning and always to a level that is devastating to a degree.Eighteen percent of women are thought to suffer from migraine, and Konnikova thinks that it’s not a coincidence that the ailment has not gotten the medical investigation that it deserves. It is unfortunately far too common to see medical data gaps where a predominantly female patient population is concerned.Informative and entertaining, Migraine is an Audible Original for those who suffer from migraine and those with sufferers in their lives—which would amount to just about everyone.

    With a wealth of detail, "A Journal of the Plague Year" seems almost a firsthand account, taking readers through the neighborhoods, houses, and streets that have drastically changed with the rising death toll. The bustle of business and errands gives way to doors marked with the cross to signify a house of death, as well as the dead-carts transporting those struck down to the mass graves as the dead rise in number to nearly 100,000. As the epidemic progresses and the narrator encounters more stories of isolation and horror, Defoe reveals his masterful balance as both a historical and imaginative writer.

    Plus, it helps you identify areas of weakness so you can focus your study time. Sample problems and step-by-step examples with explanations in the math and physics sections show you how to work through each problem so you understand the steps it takes to complete the equation. Practice tests with answer keys for each topic - located in the appendices for quick access - help you assess your understanding of each topic and familiarize you with the types of questions you're likely to encounter on the actual exam. HESI Hints boxes offer valuable test-taking tips, as well as rationales, suggestions, examples, and reminders for specific topics.End-of-chapter review questions help you gauge your understanding of chapter content.A full-color layout and more illustrations in the life science chapters visually reinforce key concepts for better understanding.Expanded and updated content in each chapter ensures you're studying the most current content.Basic algebra review in the math section offers additional review and practice.Color-coded chapters help you quickly find specific topic sections.Helpful organizational features in each chapter include an introduction, key terms, chapter outline, and a bulleted chapter summary to help you focus your study.A glossary at the end of the text offers quick access to key terms and their definitions.

    Because of his studies of the Eskimos, his discoveries of land, the application of new ideas and new methods of exploration, Stefansson was considered the foremost polar explorer of his day, and one of the few great explorers of all time. During a period of three or four years Mr. Stefansson has produced a creditable list of books about the Arctic. In some respects his service in publishing the results of his Northern studies has differed from that of earlier explorers. He has challenged our preconceptions about the Arctic. “Hunters of the Great North” gives details of Northern life such as have doubtless come within the experience of all Arctic explorers, but which are new to the average American reader. In short, it is an elementary text-book of the Arctic. Stefansson lived among the Eskimos of the Mackenzie River, studying their language and adopting their mode of life, and spending ten winters and thirteen summers in the polar regions. Among Stefannson's most famous discovery was that of a race of blond Eskimo on Coronation Gulf. Stefansson writes: "In the present book I have tried by means of diaries and memory to go back to the vivid impressions of my first year among the Eskimos for the story of what I saw and heard." In describing his confrontation with a polar bear, Stefansson writes: “I heard behind me a noise like the spitting of a cat or the hiss of a goose. I looked back and saw, about twenty feet away and almost above me, a polar bear. I had overestimated the bear's distance from shore, and had passed the spot where he lay. From his eye and attitude, as well as the story his trail told afterward there was no doubting his intentions: the hiss was merely his way of saying, "Watch me do it!" Or at least that is how I interpreted it; possibly the motive was chivalry, and the hiss was his way of saying Garde!” Contents I. PREPARATIONS FOR A LIFEWORK OF EXPLORATION II. DOWN THE MACKENZIE RIVER THROUGH 2000 MILES OF INDIAN COUNTRY III. FIRST IMPRESSIONS OF THE ESKIMOS IV. CAPTAIN KLINKENBERG—SEA WOLF AND DISCOVERER V. THE WHALING FLEET SAILS AWAY VI. LEARNING TO LIVE AS AN ESKIMO—ON A DIET OF FISH WITHOUT SALT VII. HOW AN ESKIMO SAILED THROUGH THE STORM VIII. AN AUTUMN JOURNEY THROUGH ARCTIC MOUNTAINS IX. THE SUN GOES AWAY FOR THE WINTER X. LOST IN THE MACKENZIE DELTA XI. AN ARCTIC CHRISTMAS WITH AN ENGLISH COUNTRY GENTLEMAN XII. THE LIFE AT TUKTUYAKTOK XIII. LEARNING TO BUILD A SNOWHOUSE AND TO BE COMFORTABLE IN ONE XIV. TRAVELS AFTER THE SUN CAME BACK XV. WE GO IN SEARCH OF OUR OWN EXPEDITION XVI. A SPRING JOURNEY IN AN ESKIMO SKIN BOAT XVII. A RACE OVER THE ARCTIC MOUNTAINS IN SUMMER XVIII. ON A RAFT DOWN THE PORCUPINE RIVER SHORT STORIES OF ADVENTURE I. HOW I LEARNED TO HUNT CARIBOU II. HOW I LEARNED TO HUNT SEALS III. HOW WE HUNT POLAR BEARS

    But for thousands of years, people have done things like this—and things that make radioactive underpants seem downright sensible! In their hit podcast, Sawbones, Sydnee and Justin McElroy breakdown the weird and wonderful way we got to modern healthcare. And some of the terrifying detours along the way.Every week, Dr. Sydnee McElroy and her husband Justin amaze, amuse, and gross out (depending on the week) hundreds of thousands of avid listeners to their podcast, Sawbones. Consistently rated a top podcast on iTunes, with over 15 million total downloads, this rollicking journey through thousands of years of medical mishaps and miracles is not only hilarious but downright educational. While you may never even consider applying  boiled weasel to your forehead (once the height of sophistication when it came to headache cures), you will almost certainly face some questionable medical advice in your everyday life (we’re looking at you, raw water!) and be better able to figure out if this is a miracle cure (it’s not) or a scam. Table of Contents:Part One: The Unnerving The Resurrection Men Fun w Galvanism Weird Weight Loss Miracle Cure: Opium Black Plague Heroes of Misguided Medicine: Pliny the Elder Erectile Dysfunction The Doctor Is In: Listener Questions Answered Don’t Drill a Hole in Your HeadPart Two: The Gross Mummy Medicine The Guthole Bromance The Unkillable Phineas Gage Max Drank Poopy Water Heroes of Misguided Medicine: Robert Liston Golden Showers of Health Miracle Cure-All: Radium Dr. John Romulus Brinkley The Doctor Is In Q&A Just (Four) Humour Me The Camel Dung MiraclePart Three: The Weird The Dancing Plague Bad Medicine: Tobacco for Health The Seasick-Proof Saloon Miracle Cure-All: Vinegar The Doctor Is In Q&A Heroes of Misguided MedicinePart Four: The Awesome The Poison Squad Bad Medicine: Self Experimentation Eat Your Chocolate! Heroes of Misguided Medicine Parrot Fever Miracle Cure-All: Honey The Miraculous Polio Vaccine The Doctor Is In

    All chapters have been thoroughly updated with the latest information as well as new case studies, practice questions, and exercises. This latest edition not only covers the how of clinical testing but also places greater emphasis on the what, why, and when in order to meet the needs of today's clinical laboratorians. A companion Website offers the full text online, objectives, a quiz bank, flashcards, glossary, and appendices for students and improved instructor's resources.

    The doctor-patient relationship--the heart of medicine--is broken: doctors are too distracted and overwhelmed to truly connect with their patients, and medical errors and misdiagnoses abound. In Deep Medicine, leading physician Eric Topol reveals how artificial intelligence can help. AI has the potential to transform everything doctors do, from notetaking and medical scans to diagnosis and treatment, greatly cutting down the cost of medicine and reducing human mortality. By freeing physicians from the tasks that interfere with human connection, AI will create space for the real healing that takes place between a doctor who can listen and a patient who needs to be heard.Innovative, provocative, and hopeful, Deep Medicine shows us how the awesome power of AI can make medicine better, for all the humans involved.

    Every new reader's brain possesses the extraordinary capacity to rearrange itself beyond its original abilities in order to understand written symbols. But how does the brain learn to read? As world-renowned cognitive neuroscientist and scholar of reading Maryanne Wolf explains in this impassioned book, we taught our brain to read only a few thousand years ago, and in the process changed the intellectual evolution of our species.Wolf tells us that the brain that examined tiny clay tablets in the cuneiform script of the Sumerians is configured differently from the brain that reads alphabets or of one literate in today's technology.There are critical implications to such an evolving brain. Just as writing reduced the need for memory, the proliferation of information and the particular requirements of digital culture may short-circuit some of written language's unique contributions—with potentially profound consequences for our future.Turning her attention to the development of the individual reading brain, Wolf draws on her expertise in dyslexia to investigate what happens when the brain finds it difficult to read. Interweaving her vast knowledge of neuroscience, psychology, literature, and linguistics, Wolf takes the reader from the brains of a pre-literate Homer to a literacy-ambivalent Plato, from an infant listening to Goodnight Moon to an expert reader of Proust, and finally to an often misunderstood child with dyslexia whose gifts may be as real as the challenges he or she faces.As we come to appreciate how the evolution and development of reading have changed the very arrangement of our brain and our intellectual life, we begin to realize with ever greater comprehension that we truly are what we read. Ambitious, provocative, and rich with examples, Proust and the Squid celebrates reading, one of the single most remarkable inventions in history. Once embarked on this magnificent story of the reading brain, you will never again take for granted your ability to absorb the written word.