In How to Clone a Mammoth, Beth Shapiro, evolutionary biologist and pioneer in "ancient DNA" research, walks readers through the astonishing and controversial process of de-extinction. From deciding which species should be restored, to sequencing their genomes, to anticipating how revived populations might be overseen in the wild, Shapiro vividly explores the extraordinary cutting-edge science that is being used--today--to resurrect the past. Journeying to far-flung Siberian locales in search of ice age bones and delving into her own research--as well as those of fellow experts such as Svante Paabo, George Church, and Craig Venter--Shapiro considers de-extinction's practical benefits and ethical challenges. Would de-extinction change the way we live? Is this really cloning? What are the costs and risks? And what is the ultimate goal?Using DNA collected from remains as a genetic blueprint, scientists aim to engineer extinct traits--traits that evolved by natural selection over thousands of years--into living organisms. But rather than viewing de-extinction as a way to restore one particular species, Shapiro argues that the overarching goal should be the revitalization and stabilization of contemporary ecosystems. For example, elephants with genes modified to express mammoth traits could expand into the Arctic, re-establishing lost productivity to the tundra ecosystem.Looking at the very real and compelling science behind an idea once seen as science fiction, How to Clone a Mammoth demonstrates how de-extinction will redefine conservation's future.

    Illustrations.

    They have brains that are huge for their body size and exhibit an avian kind of eloquence. They mate for life and associate with relatives and neighbors for years. And because they often live near people—in our gardens, parks, and cities—they are also keenly aware of our peculiarities, staying away from and even scolding anyone who threatens or harms them and quickly learning to recognize and approach those who care for and feed them, even giving them numerous, oddly touching gifts in return. With his extraordinary research on the intelligence and startling abilities of corvids—crows, ravens, and jays—scientist John Marzluff teams up with artist-naturalist Tony Angell to tell amazing stories of these brilliant birds in Gifts of the Crow. With narrative, diagrams, and gorgeous line drawings, they offer an in-depth look at these complex creatures and our shared behaviors. The ongoing connection between humans and crows—a cultural coevolution—has shaped both species for millions of years. And the characteristics of crows that allow this symbiotic relationship are language, delinquency, frolic, passion, wrath, risk-taking, and awareness—seven traits that humans find strangely familiar. Crows gather around their dead, warn of impending doom, recognize people, commit murder of other crows, lure fish and birds to their death, swill coffee, drink beer, turn on lights to stay warm, design and use tools, use cars as nutcrackers, windsurf and sled to play, and work in tandem to spray soft cheese out of a can. Their marvelous brains allow them to think, plan, and reconsider their actions. With its abundance of funny, awe-inspiring, and poignant stories, Gifts of the Crow portrays creatures who are nothing short of amazing. A testament to years of painstaking research and careful observation, this fully illustrated, riveting work is a thrilling look at one of nature’s most wondrous creatures.

    The story begins in Africa, six to seven million years ago, and encompasses twenty known human species, of which Homo sapiens is the sole survivor. Illustrated with spectacular, three-dimensional scientific reconstructions portrayed in their natural habitat developed by a team of physical anthropologists at the American Museum of Natural History and in concert with experts from around the world, the book is both a guide to extinct human species and an astonishing hominid family photo album.The Last Human presents a comprehensive account of each species with information on its emergence, chronology, geographic range, classification, physiology, lifestyle, habitat, environment, cultural achievements, co-existing species, and possible reasons for extinction. Also included are summaries of fossil discoveries, controversies, and publications. What emerges from the fossil story is a new understanding of Homo sapiens. No longer credible is the notion that our species is the end product of a single lineage, improved over generations by natural selection. Rather, the fossil record shows, we are a species with widely varied precursors, and our family tree is characterized by many branchings and repeated extinctions.Exhibition information:Photographs of most of the reconstructions that appear in this book will be featured in exhibits appearing in the new Hall of Human Origins at the American Museum of Natural History in New York City.  The opening of the Hall is planned for November 2006.

    Sherwin Nuland, “a gifted and deeply intelligent writer” (San Francisco Chronicle), combines knowledge, compassion, and elegance of expression to shed light on the workings of our bodies from the perspective of a surgeon. Dr. Nuland recounts age-old legends about the functions and "personalities" of the body's organs and, in riveting vignettes of the surgery he has performed, he describes the connections between myth and reality. A brilliant blend of science and folklore, The Mysteries Within reveals the enigmas not only of the body but also of the human imagination.

    In what has become one of science's greatest riddles, these large animals vanished in North and South America around the time humans arrived at the end of the last great ice age. Part paleontological adventure and part memoir, Twilight of the Mammoths presents in detail internationally renowned paleoecologist Paul Martin's widely discussed and debated "overkill" hypothesis to explain these mysterious megafauna extinctions. Taking us from Rampart Cave in the Grand Canyon, where he finds himself "chest deep in sloth dung," to other important fossil sites in Arizona and Chile, Martin's engaging book, written for a wide audience, uncovers our rich evolutionary legacy and shows why he has come to believe that the earliest Americans literally hunted these animals to death.As he discusses the discoveries that brought him to this hypothesis, Martin relates many colorful stories and gives a rich overview of the field of paleontology as well as his own fascinating career. He explores the ramifications of the overkill hypothesis for similar extinctions worldwide and examines other explanations for the extinctions, including climate change. Martin's visionary thinking about our missing megafauna offers inspiration and a challenge for today's conservation efforts as he speculates on what we might do to remedy this situation—both in our thinking about what is "natural" and in the natural world itself.

    Radiometric dating of nearby rocks indicated the skeleton, classified as Ardipithecus ramidus, was 4.4 million years old, more than a million years older than "Lucy," then the oldest known human ancestor. The findings challenged many assumptions about human evolution--how we started walking upright, how we evolved our nimble hands, and, most significantly, whether we were descended from an ancestor that resembled today's chimpanzee--and repudiated a half-century of paleoanthropological orthodoxy.Fossil Men is the first full-length exploration of Ardi, the fossil men who found her, and her impact on what we know about the origins of the human species. It is a scientific detective story played out in anatomy and the natural history of the human body. Kermit Pattison brings into focus a cast of eccentric, obsessive scientists, including one of the world's greatest fossil hunters, Tim White--an exacting and unforgiving fossil hunter whose virtuoso skills in the field were matched only by his propensity for making enemies; Gen Suwa, a Japanese savant who sometimes didn't bother going home at night to devote more hours to science; Owen Lovejoy, a onetime creationist-turned-paleoanthropologist; Berhane Asfaw, who survived imprisonment and torture to become Ethiopia's most senior paleoanthropologist and who fought for African scientists to gain equal footing in the study of human origins; and the Leakeys, for decades the most famous family in paloanthropology.An intriguing tale of scientific discovery, obsession and rivalry that moves from the sun-baked desert of Africa and a nation caught in a brutal civil war, to modern high-tech labs and academic lecture halls, Fossil Men is popular science at its best, and a must read for fans of Jared Diamond, Richard Dawkins, and Edward O. Wilson.

    Assuming the reader has little prior knowledge of the subject its importance, the principles of the techniques used and their applications are all carefully laid out, with over 250 clearly presented two-colour illustrations. In addition to a number of informative changes to the text throughout the book, the final four chapters have been significantly updated and extended to reflect the striking advances made in recent years in the applications of gene cloning and DNA analysis in biotechnology: Extended chapter on agriculture including new material on glyphosate resistant plantsNew section on the uses of gene cloning and PCR in archaeologyCoverage of ethical concerns relating to pharming, gene therapy and GM crops Gene Cloning and DNA Analysis remains an essential introductory text to a wide range of biological sciences students; including genetics and genomics, molecular biology, biochemistry, immunology and applied biology. It is also a perfect introductory text for any professional needing to learn the basics of the subject. All libraries in universities where medical, life and biological sciences are studied and taught should have copies available on their shelves. View the Gene Cloning and DNA Analysis webpage at www.blackwellpublishing.com/genecloning

    Carroll, a recognized leader in the field of evolutionary development, to this new edition of Introduction to Genetic Analysis (IGA). The authors’ ambitious new plans for this edition focus on showing how genetics is practiced today. In particular, the new edition renews its emphasis on how genetic analysis can be a powerful tool for answering biological questions of all types.

    In Living With Darwin, Philip Kitcher stokes the flames swirling around Darwin's theory, sifting through the scientific evidence for evolution, Creation Science, and Intelligent Design, and revealing why evolution has been the object of such vehement attack. Kitcher first provides valuable perspective on the present controversy, describing the many puzzles that blocked evolution's acceptance in the early years, and explaining how scientific research eventually found the answers to these conundrums. Interestingly, Kitcher shows that many of these early questions have been resurrected in recent years by proponents of Intelligent Design. In fact, Darwin himself considered the issue of intelligent design, and amassed a mountain of evidence that effectively refuted the idea. Kitcher argues that the problem with Intelligent Design isn't that it's not science, as many critics say, but that it's dead science, raising questions long resolved by scientists. But Kitcher points out that it is also important to recognize the cost of Darwin's success--the price of life with Darwin. Darwinism has a profound effect on our understanding of our place in the universe, on our religious beliefs and aspirations. It is in truth the focal point of a larger clash between religious faith and modern science. Unless we can resolve this larger issue, the war over evolution will go on.

    In captivity, octopuses have been known to identify individual human keepers, raid neighboring tanks for food, turn off lightbulbs by spouting jets of water, plug drains, and make daring escapes. How is it that a creature with such gifts evolved through an evolutionary lineage so radically distant from our own? What does it mean that evolution built minds not once but at least twice? The octopus is the closest we will come to meeting an intelligent alien. What can we learn from the encounter?In Other Minds, Peter Godfrey-Smith, a distinguished philosopher of science and a skilled scuba diver, tells a bold new story of how subjective experience crept into being—how nature became aware of itself. As Godfrey-Smith stresses, it is a story that largely occurs in the ocean, where animals first appeared. Tracking the mind’s fitful development, Godfrey-Smith shows how unruly clumps of seaborne cells began living together and became capable of sensing, acting, and signaling. As these primitive organisms became more entangled with others, they grew more complicated. The first nervous systems evolved, probably in ancient relatives of jellyfish; later on, the cephalopods, which began as inconspicuous mollusks, abandoned their shells and rose above the ocean floor, searching for prey and acquiring the greater intelligence needed to do so. Taking an independent route, mammals and birds later began their own evolutionary journeys.But what kind of intelligence do cephalopods possess? Drawing on the latest scientific research and his own scuba-diving adventures, Godfrey-Smith probes the many mysteries that surround the lineage. How did the octopus, a solitary creature with little social life, become so smart? What is it like to have eight tentacles that are so packed with neurons that they virtually “think for themselves”? What happens when some octopuses abandon their hermit-like ways and congregate, as they do in a unique location off the coast of Australia?By tracing the question of inner life back to its roots and comparing human beings with our most remarkable animal relatives, Godfrey-Smith casts crucial new light on the octopus mind—and on our own.

    But countless questions remain about our great journey from the birthplace of Homo sapiens to the ends of the Earth. How did we end up where we are? When did we get there? Why do we display such a wide range of colors and features? The fossil record offers some answers, but exciting new genetic research reveals many more, since our DNA carries a complete chronicle of our species and its migrations. In Deep Ancestry, scientist and explorer Spencer Wells shows how tiny genetic changes add up over time into a fascinating story. Using scores of real-life examples, helpful analogies, and detailed diagrams and illustrations, he translates complicated concepts into accessible language and explains exactly how each and every individual's DNA contributes another piece to the jigsaw puzzle of human history. The book takes readers inside the Genographic Project, the landmark study now assembling the world's largest collection of population genetic DNA samples and employing the latest in testing technology and computer analysis to examine hundreds of thousands of genetic profiles from all over the globe. Traveling backward through time from today's scattered billions to the handful of early humans who are ancestors to us all, Deep Ancestry shows how universal our human heritage really is. It combines sophisticated science with our compelling interest in family history and ethnic identity—and transcends humankind's shallow distinctions and superficial differences to touch the depths of our common origins.

    Black and white photographs are provided. The fifth edition adds a chapter on a

    Increased emphasis on gene activity, signal transduction and the emphasis on the roles of paracrine factors in development.

    Contrary to what the glossy magazines would have us believe, we do not enjoy potato chips because they crunch just like the insects our forebears snacked on. As Zuk argues, such beliefs incorrectly assume that we’re stuck—finished evolving—and have been for tens of thousands of years. She draws on fascinating evidence that examines everything from adults’ ability to drink milk to the texture of our ear wax to show that we’ve actually never stopped evolving. Our nostalgic visions of an ideal evolutionary past in which we ate, lived, and reproduced as we were “meant to” fail to recognize that we were never perfectly suited to our environment. Evolution is about change, and every organism is full of trade-offs.From debunking the caveman diet to unraveling gender stereotypes, Zuk gives an analysis of widespread paleofantasies and the scientific evidence that undermines them, all the while broadening our understanding of our origins and what they can really tell us about our present and our future.