We take for granted that we can remember, feel emotion, navigate, empathize, and understand the world around us, but how would our lives change if these abilities were dramatically enhanced--or disappeared overnight?Helen Thomson has spent years traveling the world, tracking down incredibly rare brain disorders. In Unthinkable she tells the stories of nine extraordinary people she encountered along the way. From the man who thinks he's a tiger to the doctor who feels the pain of others just by looking at them to a woman who hears music that’s not there, their experiences illustrate how the brain can shape our lives in unexpected and, in some cases, brilliant and alarming ways.Story by remarkable story, Unthinkable takes us on an unforgettable journey through the human brain. Discover how to forge memories that never disappear, how to grow an alien limb, and how to make better decisions. Learn how to hallucinate and how to make yourself happier in a split second. Find out how to avoid getting lost, how to see more of your reality, even how exactly you can confirm you are alive. Think the unthinkable.

    For centuries, the power of zero savored of the demonic; once harnessed, it became the most important tool in mathematics. Zero follows this number from its birth as an Eastern philosophical concept to its struggle for acceptance in Europe and its apotheosis as the mystery of the black hole. Today, zero lies at the heart of one of the biggest scientific controversies of all time, the quest for the theory of everything. Elegant, witty, and enlightening, Zero is a compelling look at the strangest number in the universe and one of the greatest paradoxes of human thought.

    "A stunning memoir from the astronaut who spent a record-breaking year aboard the International Space Station – a candid account of his remarkable voyage, the journeys that preceded it, and his colorful formative years." Inside book cover comments.

    Charles Darwin played a crucial part in turning heredity into a scientific question, and yet he failed spectacularly to answer it. The birth of genetics in the early 1900s seemed to do precisely that. Gradually, people translated their old notions about heredity into a language of genes. As the technology for studying genes became cheaper, millions of people ordered genetic tests to link themselves to missing parents, to distant ancestors, to ethnic identities. . . .But, Zimmer writes, "Each of us carries an amalgam of fragments of DNA, stitched together from some of our many ancestors. Each piece has its own ancestry, traveling a different path back through human history. A particular fragment may sometimes be cause for worry, but most of our DNA influences who we are--our appearance, our height, our penchants--in inconceivably subtle ways." Heredity isn't just about genes that pass from parent to child. Heredity continues within our own bodies, as a single cell gives rise to trillions of cells that make up our bodies. We say we inherit genes from our ancestors--using a word that once referred to kingdoms and estates--but we inherit other things that matter as much or more to our lives, from microbes to technologies we use to make life more comfortable. We need a new definition of what heredity is and, through Carl Zimmer's lucid exposition and storytelling, this resounding tour de force delivers it. Weaving historical and current scientific research, his own experience with his two daughters, and the kind of original reporting expected of one of the world's best science journalists, Zimmer ultimately unpacks urgent bioethical quandaries arising from new biomedical technologies, but also long-standing presumptions about who we really are and what we can pass on to future generations.

    Robert Oppenheimer, "father of the atomic bomb," the brilliant, charismatic physicist who led the effort to capture the awesome fire of the sun for his country in time of war. Immediately after Hiroshima, he became the most famous scientist of his generation-one of the iconic figures of the twentieth century, the embodiment of modern man confronting the consequences of scientific progress. He was the author of a radical proposal to place international controls over atomic materials-an idea that is still relevant today. He opposed the development of the hydrogen bomb and criticized the Air Force's plans to fight an infinitely dangerous nuclear war. In the now almost-forgotten hysteria of the early 1950s, his ideas were anathema to powerful advocates of a massive nuclear buildup, and, in response, Atomic Energy Commission chairman Lewis Strauss, Superbomb advocate Edward Teller and FBI director J. Edgar Hoover worked behind the scenes to have a hearing board find that Oppenheimer could not be trusted with America's nuclear secrets. American Prometheus sets forth Oppenheimer's life and times in revealing and unprecedented detail. Exhaustively researched, it is based on thousands of records and letters gathered from archives in America and abroad, on massive FBI files and on close to a hundred interviews with Oppenheimer's friends, relatives and colleagues.We follow him from his earliest education at the turn of the twentieth century at New York City's Ethical Culture School, through personal crises at Harvard and Cambridge universities. Then to Germany, where he studied quantum physics with the world's most accomplished theorists; and to Berkeley, California, where he established, during the 1930s, the leading American school of theoretical physics, and where he became deeply involved with social justice causes and their advocates, many of whom were communists. Then to Los Alamos, New Mexico, where he transformed a bleak mesa into the world's most potent nuclear weapons laboratory-and where he himself was transformed. And finally, to the Institute for Advanced Study in Princeton, which he directed from 1947 to 1966. American Prometheus is a rich evocation of America at midcentury, a new and compelling portrait of a brilliant, ambitious, complex and flawed man profoundly connected to its major events—the Depression, World War II and the Cold War. It is at once biography and history, and essential to our understanding of our recent past—and of our choices for the future.

    She was four years old. Marina Chapman was stolen from her housing estate and then abandoned deep in the Colombian jungle. That she survived is a miracle. Two days later, half-drugged, terrified, and starving, she came upon a troop of capuchin monkeys. Acting entirely on instinct, she tried to do what they did: she ate what they ate and copied their actions, and little by little, learned to fend for herself.So begins the story of her five years among the monkeys, during which time she gradually became feral; she lost the ability to speak, lost all inhibition, lost any real sense of being human, replacing the structure of human society with the social mores of her new simian family. But society was eventually to reclaim her. At age ten she was discovered by a pair of hunters who took her to the lawless Colombian city of Cucuta where, in exchange for a parrot, they sold her to a brothel. When she learned that she was to be groomed for prostitution, she made her plans to escape. But her adventure wasn’t over yet...In the vein of "Slumdog Millionaire" and "City of God," this rousing story of a lost child who overcomes the dangers of the wild and the brutality of the streets to finally reclaim her life will astonish readers everywhere.

    While studying brain scans of several family members, he discovered that one perfectly matched a pattern he d found in the brains of serial killers. This meant one of two things: Either his family s scans had been mixed up with those of felons or someone in his family was a psychopath.Even more disturbing: The scan in question was his own.This is Fallon s account of coming to grips with this discovery and its implications. How could he, a happy family man who had never been prone to violence, be a psychopath? How much did his biology influence his behavior?Fallon shares his journey to answer these questions and the discoveries that ultimately led to his conclusion: Despite everything science can teach, humans are even more complex than we can imagine."

    For most of that time, she didn't know why. All of her trips to the ER and her daily anguish, pain, and lethargy only ever resulted in one question: How could any one person be this sick? Several drug addictions, three major hospitalizations, and over $100,000 later, she finally had a diagnosis: late-stage Lyme disease. Sick is Khakpour's arduous, emotional journey—as a woman, a writer, and a lifelong sufferer of undiagnosed health problems—through the chronic illness that perpetually left her a victim of anxiety, living a life stymied by an unknown condition.Divided by settings, Khakpour guides the reader through her illness by way of the locations that changed her course—New York, LA, New Mexico, and Germany—as she meditates on both the physical and psychological impacts of uncertainty, and the eventual challenge of accepting the diagnosis she had searched for over the course of her adult life. With candor and grace, she examines her subsequent struggles with mental illness, her addiction to the benzodiazepines prescribed by her psychiatrists, and her ever-deteriorating physical health. A story about survival, pain, and transformation, Sick is a candid, illuminating narrative of hope and uncertainty, boldly examining the deep impact of illness on one woman's life.

    Ballet dancers and rock musicians, professors and thieves-"anyone who had fallen, or, often, leapt, onto hard times" and needed extended medical care-ended up here. So did Victoria Sweet, who came for two months and stayed for twenty years. Laguna Honda, lower tech but human paced, gave Sweet the opportunity to practice a kind of attentive medicine that has almost vanished. Gradually, the place transformed the way she understood her work. Alongside the modern view of the body as a machine to be fixed, her extraordinary patients evoked an older idea, of the body as a garden to be tended. God's Hotel tells their story and the story of the hospital itself, which, as efficiency experts, politicians, and architects descended, determined to turn it into a modern "health care facility," revealed its own surprising truths about the essence, cost, and value of caring for body and soul.

    Little did he know, as he kissed her good-bye, that he would spend the next three months in Iran’s most notorious prison, enduring brutal interrogation sessions at the hands of a man he knew only by his smell: Rosewater.For the Bahari family, wars, coups, and revolutions are not distant concepts but intimate realities they have suffered for generations: Maziar’s father was imprisoned by the shah in the 1950s, and his sister by Ayatollah Khomeini in the 1980s. Alone in his cell at Evin Prison, fearing the worst, Maziar draws strength from his memories of the courage of his father and sister in the face of torture, and hears their voices speaking to him across the years. He dreams of being with Paola in London, and imagines all that she and his rambunctious, resilient eighty-four-year-old mother must be doing to campaign for his release. During the worst of his encounters with Rosewater, he silently repeats the names of his loved ones, calling on their strength and love to protect him and praying he will be released in time for the birth of his first child. A riveting, heart-wrenching memoir, Rosewater offers insight into the past seventy years of regime change in Iran, as well as the future of a country where the democratic impulses of the youth continually clash with a government that becomes more totalitarian with each passing day. An intimate and fascinating account of contemporary Iran, it is also the moving and wonderfully written story of one family’s extraordinary courage in the face of repression.Now a major motion picture directed by Jon Stewart - Previously published as Then They Came for Me.

    After World War II, Don's work with the Air Force brought them to Colorado, where their twelve children perfectly spanned the baby boom: the oldest born in 1945, the youngest in 1965. In those years, there was an established script for a family like the Galvins—aspiration, hard work, upward mobility, domestic harmony—and they worked hard to play their parts. But behind the scenes was a different story: psychological breakdown, sudden shocking violence, hidden abuse. By the mid-1970s, six of the ten Galvin boys, one after another, were diagnosed as schizophrenic. How could all this happen to one family?What took place inside the house on Hidden Valley Road was so extraordinary that the Galvins became one of the first families to be studied by the National Institute of Mental Health. Their story offers a shadow history of the science of schizophrenia, from the era of institutionalization, lobotomy, and the schizophrenogenic mother to the search for genetic markers for the disease, always amid profound disagreements about the nature of the illness itself. And unbeknownst to the Galvins, samples of their DNA informed decades of genetic research that continues today, offering paths to treatment, prediction, and even eradication of the disease for future generations.With clarity and compassion, bestselling and award-winning author Robert Kolker uncovers one family's unforgettable legacy of suffering, love, and hope.

    The Sackler name adorns the walls of many storied institutions: Harvard, the Metropolitan Museum of Art, Oxford, the Louvre. They are one of the richest families in the world, known for their lavish donations to the arts and sciences. The source of the family fortune was vague, however, until it emerged that the Sacklers were responsible for making and marketing OxyContin, a blockbuster painkiller that was a catalyst for the opioid crisis.Empire of Pain is a masterpiece of narrative reporting and writing, exhaustively documented and ferociously compelling.

    No cloistered don, this tall, married Englishman was a freethinking intellectual. A nudist, he was devoted to quirky folk dancing. In 1937, while working as a biochemist at Cambridge, he fell in love with a visiting Chinese student, with whom he began a lifelong affair. His mistress persuaded him to travel to her home country, where he embarked on a series of expeditions to the frontiers of the ancient empire. He searched for evidence to bolster a conviction that the Chinese were responsible for hundreds of humankind's most familiar innovations—including printing, the compass, explosives, suspension bridges, even toilet paper—often centuries before others. His journeys took him across war-torn China, consolidating his admiration for the Chinese. After the war, he determined to announce what he'd discovered & began writing Science & Civilization in China, describing the country's long history of invention & technology. By the time he died, he'd produced, almost single-handedly, 17 volumes, making him the greatest one-man encyclopedist ever. Epic & intimate, The Man Who Loved China tells the sweeping story of China thru Needham's life. Here's a tale of what makes men, nations & humankind great—related by one of the world's best storytellers.

    A group of young scientists, under the guidance of Dr. George Church, the most brilliant geneticist of our time, works to make fantasy reality by sequencing the DNA of a frozen woolly mammoth harvested from above the Arctic circle, and splicing elements of that sequence into the DNA of a modern elephant. Will they be able to turn the hybrid cells into a functional embryo and bring the extinct creatures to life in our modern world?Along with Church and his team of Harvard scientists, a world-famous conservationist and a genius Russian scientist plan to turn a tract of the Siberian tundra into Pleistocene Park, populating the permafrost with ancient herbivores as a hedge against an environmental ticking time bomb.

    Determined to clone an endangered flower—the rare ghost orchid Polyrrhiza lindenii—a deeply eccentric and oddly attractive man named John Laroche leads Orlean on an unforgettable tour of America’s strange flower-selling subculture, through Florida’s swamps and beyond, along with the Seminoles who help him and the forces of justice who fight him. In the end, Orlean—and the reader—will have more respect for underdog determination and a powerful new definition of passion.   In this new edition, coming fifteen years after its initial publication and twenty years after she first met the “orchid thief,” Orlean revisits this unforgettable world, and the route by which it was brought to the screen in the film Adaptation, in a new retrospective essay.