Written in short, carefully numbered paragraphs of extreme brilliance, it captured the imagination of a generation of philosophers. For Wittgenstein, logic was something we use to conquer a reality which is in itself both elusive and unobtainable. He famously summarized the book in the following words: 'What can be said at all can be said clearly; and what we cannot talk about we must pass over in silence.' David Pears and Brian McGuinness received the highest praise for their meticulous translation. The work is prefaced by Bertrand Russell's original introduction to the first English edition.

    Around the world, thousands of people have found inspiration in the words of Cheryl Strayed, who in her three prior books and in her Dear Sugar columns has shared the twists and trials of her remarkable life. Her honesty, spirit, and ample supply of tough love have enabled many of us, even in the darkest hours, to somehow put one foot in front of the other--and be brave enough.This book gathers, each on a single page, more than 100 of Strayed's indelible quotes and thoughts--"mini instruction manuals for the soul" that urge us toward the incredible capacity for love, compassion, forgiveness, and endurance that is within us all.Be brave enough to break your own heart.You can't ride to the fair unless you get on the pony.Keep walking.Acceptance is a small, quiet room.Romantic love is not a competitive sport.Forward is the direction of real life.Ask yourself: "What is the best I can do?" And then do that.

    Why do we dream? Do dreams hold psychological meaning or are they merely the reflection of random brain activity? What purpose do dreams serve?When Brains Dream addresses these core questions about dreams while illuminating the most up-to-date science in the field. Written by two world-renowned sleep and dream researchers, it debunks common myths; that we only dream in REM sleep, for example—while acknowledging the mysteries that persist around both the science and experience of dreaming.Antonio Zadra and Robert Stickgold bring together state-of-the-art neuroscientific ideas and findings to propose a new and innovative model of dream function called NEXTUP—Network Exploration to Understand Possibilities. By detailing this model’s workings, they help readers understand key features of several types of dreams, from prophetic dreams to nightmares and lucid dreams.

     Long treasured by literary readers for her uncommon ability to bridge the gap between art and science, celebrated scholar-artist Diane Ackerman returns with the book she was born to write. Her dazzling new work, An Alchemy of Mind, offers an unprecedented exploration and celebration of the mental fantasia in which we spend our days—and does for the human mind what the bestselling A Natural History of the Senses did for the physical senses. Bringing a valuable female perspective to the topic, Diane Ackerman discusses the science of the brain as only she can: with gorgeous, immediate language and imagery that paint an unusually lucid and vibrant picture for the reader. And in addition to explaining memory, thought, emotion, dreams, and language acquisition, she reports on the latest discoveries in neuroscience and addresses controversial subjects like the effects of trauma and male versus female brains. In prose that is not simply accessible but also beautiful and electric, Ackerman distills the hard, objective truths of science in order to yield vivid, heavily anecdotal explanations about a range of existential questions regarding consciousness, human thought, memory, and the nature of identity.

    In 1996 Joseph LeDoux's "The Emotional Brain" presented a revelatory examination of the biological bases of our emotions and memories. Now, the world-renowned expert on the brain has produced with a groundbreaking work that tells a more profound story: how the little spaces between the neurons-the brain's synapses--are the channels through which we think, act, imagine, feel, and remember. Synapses encode the essence of personality, enabling each of us to function as a distinctive, integrated individual from moment to moment. Exploring the functioning of memory, the synaptic basis of mental illness and drug addiction, and the mechanism of self-awareness, "Synaptic Self" is a provocative and mind-expanding work that is destined to become a classic.

    Winner of the Society of Midland Authors Award, this wonderfully crafted collection on medical subjects is witty, urbane, and rich in history and philosophy. "Marvelously original and provocative" (Los Angeles Times).

    - A.D. 65) acquired as Nero's minister were in conflict with his Stoic beliefs. Nevertheless he was the outstanding figure of his age. The Stoic philosophy which Seneca professed in his writings, later supported by Marcus Aurelius, provided Rome with a passable bridge to Christianity. Seneca's major contribution to Stoicism was to spiritualize and humanize a system which could appear cold and unrealistic.Selected from the Epistulae Morales ad Lucilium, these letters illustrate the upright ideals admired by the Stoics and extol the good way of life as seen from their standpoint. They also reveal how far in advance of his time were many of Seneca's ideas - his disgust at the shows in the arena or his criticism of the harsh treatment of slaves. Philosophical in tone and written in the 'pointed' style of the Latin Silver Age these 'essays in disguise' were clearly aimed by Seneca at posterity.

    He asks: How do we "read" other people?What is the neurochemistry behind love and sex?What does it mean that the brain is teeming with powerful chemicals closely related to recreational drugs?Why does music move us to tears?Where do breakthrough ideas come from? Johnson answers these and many more questions arising from the events of our everyday lives. You do not have to be a neuroscientist to wonder, for example, why do you smile? And why do you sometimes smile inappropriately, even if you don't want to? How do others read your inappropriate smile? How does such interplay occur neurochemically, and what, if anything, can you do about it? Fascinating and rewarding, Mind Wide Open speaks to brain buffs, self-obsessed neurotics, barstool psychologists, mystified parents, grumpy spouses, exasperated managers, and anyone who enjoys speculating and gossiping about the motivations and behaviors of other human beings. Steven Johnson shows us the transformative power of understanding brain science and offers new modes of introspection and tools for better parenting, better relationships, and better living.

    "A profoundly moving, brilliantly perceptive essay by a truly civilized man."--Scientific American

    The medical world has generally ignored these “near-death experiences,” dismissing them as “tricks of the brain” or wishful thinking. But after his patients started describing events that he could not just sweep under the rug, Dr. Bruce Greyson began to investigate.As a physician without a religious belief system, he approached near-death experiences from a scientific perspective. In After, he shares the transformative lessons he has learned over four decades of research. Our culture has tended to view dying as the end of our consciousness, the end of our existence—a dreaded prospect that for many people evokes fear and anxiety.But Dr. Greyson shows how scientific revelations about the dying process can support an alternative theory. Dying could be the threshold between one form of consciousness and another, not an ending but a transition. This new perspective on the nature of death can transform the fear of dying that pervades our culture into a healthy view of it as one more milestone in the course of our lives. After challenges us to open our minds to these experiences and to what they can teach us, and in so doing, expand our understanding of consciousness and of what it means to be human.

     Auditory hallucination is one of the most awe-inspiring, terrifying, and ill-understood tricks the human psyche is capable of. Muses, Madmen, and Prophets reevaluates the popular conception of the phenomenon today and through the ages, and reveals the roots of the medical understanding and treatment of it. It probes history, literature, anthropology, psychology, and neurology to explain and demystify the experience of hearing voices, in a fascinating and at times funny quest for understanding. Daniel B. Smith's personal experience with the phenomenon-his father heard voices, and it was the great torment and shame of his father's life-and his discovery that some people learn to live in peace with their voices fuels this contemplative, brilliantly researched, and inspired book. Science has not been able to fully explain the phenomenon of auditory hallucination. It is a condition that has existed perhaps as long as we have-there is evidence of it in literature and even pre-literate oral histories from across all times and cultures. Smith presents the sophisticated and radical argument that a negative side effect of living as we do in this great age of medical science is that we have come to limit this phenomenon to nothing more than a biochemical glitch for which the only proper response is medical, pharmaceutical treatment. This "pathological assumption" can inflict great harm on the people who hear voices by ignoring the meaning and reality of the experience for them. But it also obscures from the rest of us a rich wellspring of knowledge about the essential source of faith and inspiration. As Smith examines the many incidences of people who have famously heard voices throughout history-Moses, Mohammed, Teresa of Avila, Joan of Arc, Rilke, William Blake, Socrates, and others-he considers the experience of auditory hallucination in light of its relationship to the nature of pure faith and as the key to the source of artistic inspiration. At the heart of Smith's exploration into the many extraordinary, strange, sometimes frightening and sometimes almost supernatural aspects of auditory hallucination is his driving personal need to comprehend an experience that, when considered in good faith, is as profound and complex as human consciousness itself.

    Created primarily for medical and premedical students, 'Neuroscience' emphasizes the structure of the nervous system, the correlation of structure and function, and the structure/function relationships particularly pertinent to the practice of medicine.

    In the majority of cases individuals diagnosed as "brain dead" are the source of the organs without which transplants could not take place. In this compelling and provocative examination, Margaret Lock traces the discourse over the past thirty years that contributed to the locating of a new criterion of death in the brain, and its routinization in clinical practice in North America. She compares this situation with that in Japan where, despite the availability of the necessary technology and expertise, brain death was legally recognized only in 1997, and then under limited and contested circumstances. Twice Dead explores the cultural, historical, political, and clinical reasons for the ready acceptance of the new criterion of death in North America and its rejection, until recently, in Japan, with the result that organ transplantation has been severely restricted in that country. This incisive and timely discussion demonstrates that death is not self-evident, that the space between life and death is historically and culturally constructed, fluid, multiple, and open to dispute. In addition to an analysis of that professional literature on and popular representations of the subject, Lock draws on extensive interviews conducted over ten years with physicians working in intensive care units, transplant surgeons, organ recipients, donor families, members of the general public in both Japan and North America, and political activists in Japan opposed to the recognition of brain death. By showing that death can never be understood merely as a biological event, and that cultural, medical, legal, and political dimensions are inevitably implicated in the invention of brain death, Twice Dead confronts one of the most troubling questions of our era.

    To understand this remarkable trend, Charles R. Morris "embedded" himself with a surgical team at New York-Presbyterian Hospital in New York City, one of the world's premier cardiac surgery and transplant centers. Given unprecedented access, Morris witnessed sophisticated operations and observed the tense meetings where surgeons relentlessly criticize their own performance. In thrilling detail, Morris recounts a late-night against-the-clock "harvest run" to secure a precious transplantable organ; the heart-breaking story of a child's failed transplant; a trainee surgeon's brutal daily regimen; and much more. Along the way, Morris documents the fifty years of research and hundreds of millions of dollars that have been expended on creating a reliable mechanical heart, and he steps back to reflect on how doctors think and how they judge each other, what is really driving health care costs, and the future of health care policy in America.

    Major structural changes mark the revision. The authors have added a new concluding chapter on methods that, along with its companion chapter on moral theory, emphasizes convergence across theories, coherence in moral justification, and the common morality. They have simplified the opening chapter on moral norms which introduces the framework of prima facie moral principles and ways to specify and balance them. Together with the shift of advanced material on theory to the back of the book, this heavily revised introductory chapter will make it easier for the wide range of students entering bioethics courses to use this text. Another important change is the increased emphasis on character and moral agency, drawing the distinction between agents and actions. The sections on truth telling, disclosure of bad news, privacy, conflicts of interest, and research on human subjects have also been thoroughly reworked. The four core chapters on principles (respect for autonomy, nonmaleficence, beneficence, and justice) and the chapter on professional-patient relationships retain their familiar structure, but the authors have completely updated their content to reflect developments in philosophical analysis as well as in research, medicine, and health care. Throughout, they have used a number of actual cases to illuminate and to test their theory, method, and framework of principles.