But things changed dramatically when he began suffering from inexplicable fatigue. In a matter of weeks, his organs were failing and he was read his last rites. Doctors were baffled by his condition, which they had yet to even diagnose. Floating in and out of consciousness, Fajgenbaum prayed for a second chance, the equivalent of a dramatic play to second the game into overtime.Miraculously, Fajgenbaum survived--only to endure repeated near-death relapses from what would eventually be identified as a form of Castleman disease, an extremely deadly and rare condition that acts like a cross between cancer and an autoimmune disorder. When he relapsed while on the only drug in development and realized that the medical community was unlikely to make progress in time to save his life, Fajgenbaum turned his desperate hope for a cure into concrete action: Between hospitalizations he studied his own charts and tested his own blood samples, looking for clues that could unlock a new treatment. With the help of family, friends, and mentors, he also reached out to other Castleman disease patients and physicians, and eventually came up with an ambitious plan to crowdsource the most promising research questions and recruit world-class researchers to tackle them. Instead of waiting for the scientific stars to align, he would attempt to align them himself.More than five years later and now married to his college sweetheart, Fajgenbaum has seen his hard work pay off: A treatment he identified has induced a tentative remission and his novel approach to collaborative scientific inquiry has become a blueprint for advancing rare disease research. His incredible story demonstrates the potency of hope, and what can happen when the forces of determination, love, family, faith, and serendipity collide.

    But nowhere is this drive to do better more important than in medicine, where lives are on the line with every decision. In his new book, Atul Gawande explores how doctors strive to close the gap between best intentions and best performance in the face of obstacles that sometimes seem insurmountable. Gawande's gripping stories of diligence, ingenuity, and what it means to do right by people take us to battlefield surgical tents in Iraq, to labor and delivery rooms in Boston, to a polio outbreak in India, and to malpractice courtrooms around the country. He discusses the ethical dilemmas of doctors participation in lethal injections, examines the influence of money on modern medicine, and recounts the astoundingly contentious history of hand washing. And as in all his writing, Gawande gives us an inside look at his own life as a practicing surgeon, offering a searingly honest firsthand account of work in a field where mistakes are both unavoidable and unthinkable. At once unflinching and compassionate, Better is an exhilarating journey narrated by arguably the best nonfiction doctor-writer around (Salon). Gawande's investigation into medical professionals and how they progress from merely good to great provides rare insight into the elements of success, illuminating every area of human endeavor.

     In his bestselling memoir Tweak, Nic Sheff took readers on an emotionally gripping roller-coaster ride through his days as an addict. In this powerful follow-up about his continued efforts to stay clean, Nic writes candidly about eye-opening stays at rehab centers, devastating relapses, and hard-won realizations about what it means to be a young person living with addiction. By candidly revealing his own failures and small personal triumphs, Nic inspires readers to maintain hope and to remember that they are not alone in their battles. A group reading guide is included. Nic Sheff's Tweak, We All Fall Down, and his father's memoir about him (Beautiful Boy) are the basis of the film Beautiful Boy starring Steve Carell and Timothée Chalamet.

    As the cancer progressed and was treated, the author experienced behavioral and cognitive symptoms connected to a range of mental disorders, including her professional specialty, schizophrenia. Lipska's family and associates were alarmed by the changes in her behavior, which she failed to acknowledge herself. Gradually, after a course of immunotherapy, Lipska returned to normal functioning, recalled her experience and, through her knowledge of neuroscience, identified the ways in which her brain changed during treatment. Lipska admits her condition was unusual; after recovery she was able to return to her research and resume her athletic training and compete in a triathalon. Most patients with similar brain cancers rarely survive to describe their ordeal. Lipska's memoir, coauthored with journalist McArdle, shows that strength and courage but also a encouraging support network are vital to recovery

    And that's what Furiously Happy is all about."Jenny’s readings are standing room only, with fans lining up to have Jenny sign their bottles of Xanax or Prozac as often as they are to have her sign their books. Furiously Happy appeals to Jenny's core fan base but also transcends it. There are so many people out there struggling with depression and mental illness, either themselves or someone in their family—and in Furiously Happy they will find a member of their tribe offering up an uplifting message (via a taxidermied roadkill raccoon). Let's Pretend This Never Happened ostensibly was about embracing your own weirdness, but deep down it was about family. Furiously Happy is about depression and mental illness, but deep down it's about joy—and who doesn't want a bit more of that?

    But then we never think about food more than when we are hungry and we never think about life rafts more than when we are thrown overboard.”The Comfort Book is Haig’s life raft: it’s a collection of notes, lists, and stories written over a span of several years that originally served as gentle reminders to Haig’s future self that things are not always as dark as they may seem. Incorporating a diverse array of sources from across the world, history, science, and his own experiences, Haig offers warmth and reassurance, reminding us to slow down and appreciate the beauty and unpredictability of existence.

    What is it like to encounter cancer? How does it feel to face the unknown, to enter a world of hope, loss, and dread? From the diagnosis of his childhood friend's mother to his poignant memories in the lab, David Scadden's seen the unknown world of cancer from the lens of a young boy, a classmate, a researcher, a friend, a doctor, and a neighbor. Scadden chronicles his personal memories of cancer--his visits to his sick neighbor and his classmate who left school and never came back.Now Dr. David Scadden, co-founder of the Harvard Stem Cell Institute and one of the world's leading experts on immunology and oncology, writes his memoir, Cancerland , with Pulitzer Prize-winning journalist Michael D'Antonio. With riveting stories and moving compassion, Scadden and D'Antonio paint a still rapidly changing landscape in the context of all too common stories of loss. Ranging from Scadden's personal childhood memories to his triumphs and regrets as a doctor, Scadden illuminates a light at the end of a dark tunnel.Through opening a window into the science of medicine in the world of unknown, Scadden and D'Antonio humanize cancer while inspiring action that we all so desperately need.

    They fell in love at eighteen, married at twenty-four, and were living their dream life in San Francisco. When Giulia was twenty-seven, she suffered a terrifying and unexpected psychotic break that landed her in the psych ward for nearly a month. One day she was vibrant and well-adjusted; the next she was delusional and suicidal, convinced that her loved ones were not safe.Eventually, Giulia fully recovered, and the couple had a son. But, soon after Jonas was born, Giulia had another breakdown, and then a third a few years after that. Pushed to the edge of the abyss, everything the couple had once taken for granted was upended.A story of the fragility of the mind, and the tenacity of the human spirit, My Lovely Wife in the Psych Ward is, above all, a love story that raises profound questions: How do we care for the people we love? What and who do we live for? Breathtaking in its candor, radiant with compassion, and written with dazzling lyricism, Lukach’s is an intensely personal odyssey through the harrowing years of his wife’s mental illness, anchored by an abiding devotion to family that will affirm readers’ faith in the power of love.

    I hope you buy it—and not just because each purchase gets me one step closer to buying the leather pants of my dreams.I hope you buy Fat Girl Walking because I want to start a conversation. Or continue a conversation, one I inadvertently started a while ago when I took my clothes off on a stage in front of 700 people. A lot of people thought I was awesome for doing that. A lot of others thought a size 18 woman had absolutely no business showing off her body. Unfortunately for them, I've made it my personal mission on my blog, in social media, on television, and now in this amazing book you're holding, to destroy the ridiculous myth that every woman who is overweight hates her body and herself. I, Brittany Gibbons, and the Curvy Girls I speak to every day on the internet, beg to differ. We love our bodies. We love fashion. We are in loving relationships, having lots of sex. We aren't just a fetish, we're normal women. Sure, sometimes we doubt ourselves, we're not robots, but not anymore than EVERY OTHER WOMAN ON THE PLANET. See, Fat Girls aren't freaks of nature. We're just like you. Maybe we are you.Fat Girl Walking is a collection of stories from my life, my thoughts about the issues that I have faced as a woman, wife, mom, daughter, daughter-in-law, and internet personality in regards to my weight. I have tried to be as honest as I possibly could—apologies in advance to my husband and parents, but hopefully any discomfort you feel is quickly replaced by laughter. The insecure texts to my husband and summer camp hijinks are hilarious if I do say so myself. And I also ask some tough questions, things like "What if my husband weighs less than I do?" and "Is my body hate ruining my daughter's life?" Read Fat Girl Walking and let's start having these conversations. No pressure, but we may just save all of womankind.Love,Brittany

    In this captivating fusion of science, history and personal memoir, writer David Adam explores the weird thoughts that exist within every mind, and how they drive millions of us towards obsessions and compulsions.David has suffered from OCD for twenty years, and The Man Who Couldn’t Stop is his unflinchingly honest attempt to understand the condition and his experiences. What might lead an Ethiopian schoolgirl to eat a wall of her house, piece by piece; or a pair of brothers to die beneath an avalanche of household junk that they had compulsively hoarded? At what point does a harmless idea, a snowflake in a clear summer sky, become a blinding blizzard of unwanted thoughts? Drawing on the latest research on the brain, as well as historical accounts of patients and their treatments, this is a book that will challenge the way you think about what is normal, and what is mental illness.Told with fierce clarity, humour and urgent lyricism, this extraordinary book is both the haunting story of a personal nightmare, and a fascinating doorway into the darkest corners of our minds.

    You need a new road map, and fast...When Jennifer Groneberg and her husband learned they'd be having twin boys, their main concern was whether they'd need an addition on their house. Then, five days after Avery and Bennett were born, Avery was diagnosed with Down syndrome.Here, Jennifer shares the story of what followed. She dealt with doctors-some who helped, and some who were disrespectful or even dangerous. She saw some relationships in her life grow stronger, while severing ties with people who proved unsupportive. And she continues to struggle to find balance in the hardships and joys of raising a child with special needs. This book is a resource, a companion for parents, and above all, a story of the love between a mother and her son-as she learns that Avery is exactly the child she never knew she wanted.

    She wore saris and ate delicately from plates of curry at family events; elsewhere she wore a lip ring, designer shades, and a cowboy hat and ordered bloody steaks. She wrote volumes of poetry, made amateur films, singlehandedly ran a chapter of Food Not Bombs, and ended up as a fierce advertising agency executive. She often slept less than five hours per week and would, at the slightest excuse, drive from L.A. to New York in a cool 50 hours. In some moments of danger, she split the lips of menacing strangers. And she gave herself over to the casual knives and fists of others for nothing more than another bag of heroin that she had plenty of money for anyway. Clearly Now, the Rain traces the decade-long relationship of Eli Hastings and his friend Serala: from ill-advised quests for narcotics in Mexican border towns through summer road trips, from southern California to Tennessee and on to New York City and Seattle, from 1996 to the very last days of 2004, when Serala’s journey concluded tragically at age 27.

    Owsley "Bear" Stanley met her in Berkeley in 1965, when LSD was still legal and he was the world's largest producer and distributor of LSD. Rhoney found herself working in an LSD laboratory, and the third corner in a love triangle. We all know the stories from the '60s—but never from the point of view of a woman finding her way through twisted trails of love, jealousy, and paranoia, all the while personally connecting to the most iconic events and people of her time.Bear supported the Grateful Dead in their early years and gave away as much LSD as he sold—millions of hits. He designed and engineered the infamous Wall of Sound system of the early '70s, just before he began his two years in prison, with Rhoney raising their infant son. He died one year ago, but the era he helped create is now being rediscovered by a new generation interested in the meaning of it all.

    Gifted Hands will transplace you into the operating room to witness surgeries that made headlines around the world, and into the private mind of a compassionate, God-fearing physician who lives to help others. In 1987, Dr. Carson gained worldwide recognition for his part in the first successful separation of Siamese twins joined at the back of the head -- an extremely complex and delicate operation that was five months of planning and twenty-two hours of actual surgery, involving a surgical plan that Carson helped initiate. Gifted Hands reveals a man with humility, decency, compassion, courage, and sensitivity who serves as a role model for young people (and everyone else) in need of encouragement to attempt the seemingly impossible and to excel in whatever they attempt. Dr. Carson also describes the key role that his highly intelligent though relatively uneducated mother played in his metamorphosis from an unmotivated ghetto youngster into one of the most respected neurosurgeons in the world.

    Shimi Kang, psychiatrist, bestselling author of The Dolphin Parent"Jessica's ability to open up about painful things in a way that make them hilarious and beautiful is astounding! This book will make you laugh, make you feel brave and make you feel like you are normal and wonderful just the way you are!" --Aisha Alfa, comedian, Just For LaughsComedians live by the mantra tragedy ] time = comedy--hence Jessica Holmes's refreshing and hilarious new memoir about depression, "the cold sore of the mind." She takes us on her journey-- sometimes laugh-out-loud, sometimes cringe-worthy--from successful performer to someone who was basically living the life of a house cat. She muses aboutthe chicken and the egg of depression and comedy marriage counselling (a.k.a. tattling on your spouse) where jokes come from living on the sofa, which now looks like a tornado hit a 7-Eleven her kids' take on the perks of having a depressed mom: "We don't have to clean up anything. Yesterday the cat barfed and Mom just put a cushion on it and went back to playing on the iPad!" the obnoxiousness of anti-depressant commercials: "I never noticed the ocean before!" Holmes shares her two cents on how to play it cool when your medication makes you hear Kate Hudson's voice, and why you don't sneak elk pepperettes into the movies. It's a validating read for anyone who has suffered from depression a little ("I get sad every January") or a lot ("My psychiatrist doesn't have a name for what I've got") or who just thinks real life calls for levity and understanding.