And despite the advances of science, germs are challenging medicine in ways that were unimaginable ten years ago. No wonder the world is up in arms -- and using antibacterial soaps. From the common cold, E. coli, and Lyme disease to encephalitis, mad cow disease, and flesh-eating bacteria, Tierno takes readers on a historical survey of the microscopic world. Rebuffing scare tactics behind recent "germ events" Tierno explains how the recycling of matter is the key to life. Yes, he'll tell you why it's a good idea to clean children's toys, why those fluffy towels may not be so clean, and why you never want to buy a second-hand mattress, but he also reveals that there is a lot we can do to prevent germ-induced suffering. You'll never look at anything the same way again.

    Your life, your thoughts, your diseases, and your health are all the function of cells.But what do you really know about what goes on inside you?The last time most people thought about cells in any detail was probably in high school or a college general biology class. But the field of cell biology has advanced incredibly rapidly in recent decades, and a great deal of what we may have learned in high school and college is no longer accurate or particularly relevant.The Cell: Inside the Microscopic World that Determines Our Health, Our Consciousness, and Our Future is a fascinating story of the incredible complexity and dynamism inside the cell and of the fantastic advancements in our understanding of this microscopic world.Dr. Joshua Z. Rappoport is at the forefront of this field, and he will take you on a journey to discover:A deeper understanding of how cells work and the basic nature of life on earth.Fascinating histories of some of the key discoveries from the seventeenth century to the last decade and provocative thoughts on the current state of academic research.The knowledge required to better understand the new developments that are announced almost weekly in science and health care, such as cancer, cellular therapies, and the potential promise of stem cells.The ability to make better decisions about health and to debunk the misinformation that comes in daily via media.Using the latest scientific research, The Cell illustrates the diversity of cell biology and what it all means for your everyday life.

    This title is suitable for students preparing for careers in medicine, dentistry, nursing, and allied health, as well as research, teaching, and industry.

    One of the oldest forms of indigenous shelter still in use today, yurts have exploded into the twenty-first century as a multi-faceted, thoroughly modern, utterly versatile, and immensely popular modern structure whose possibilities are still being explored. Kemery introduces the innovators who redesigned the yurt and took it from back country trekking and campground uses to modern permanent homes and offices.

    Some of these drugs are truly transformative, offering major improvements in how long patients live or how they feel--but what is often missing from the popular narrative is that, far too often, these new drugs have marginal or minimal benefits. Some are even harmful. In Malignant, hematologist-oncologist Dr. Vinayak K. Prasad writes about the many sobering examples of how patients are too often failed by cancer policy and by how oncology is practiced. Throughout this work, Prasad illuminates deceptive practices which- promote novel cancer therapies long before credible data are available to support such treatment; and- exaggerate the potential benefits of new therapies, many of which cost thousands and in some cases hundreds of thousands of dollars.Prasad then critiques the financial conflicts of interest that pervade the oncology field, the pharmaceutical industry, and the US Food and Drug administration.This is a book about how the actions of human beings--our policies, our standards of evidence, and our drug regulation--incentivize the pursuit of marginal or unproven therapies at lofty and unsustainable prices. Prasad takes us through how cancer trials are conducted, how drugs come to market, and how pricing decisions are made, asking how we can ensure that more cancer drugs deliver both greater benefit and a lower price. Ultimately, Prasad says,- more cancer clinical trials should measure outcomes that actually matter to people with cancer;- patients on those trials should look more like actual global citizens;- we need drug regulators to raise, not perpetually lower, the bar for approval; and- we need unbiased patient advocates and experts.This well-written, opinionated, and engaging book explains what we can do differently to make serious and sustained progress against cancer--and how we can avoid repeating the policy and practice mistakes of the past.

    It features a biography of the author, a full-length analysis of the novel, and a great deal more. If you're studying this novel, reading it for your book club, or if you simply want to know more about it, you'll find this guide informative and helpful. Part of a new series of guides to contemporary novels. The aim of the series is to give readers accessible and informative introductions to some of the most popular, most acclaimed and most influential novels of recent years - from ‘The Remains of the Day' to ‘White Teeth'. A team of contemporary fiction scholars from both sides of the Atlantic has been assembled to provide a thorough and readable analysis of each of the novels in question.

    You’re unlikely to forget the experiences or regret the sharing.

    Cave paintings of the giant beasts hint at the profound role they played in early human culture-our Ice Age ancestors built igloo-shaped huts out of mammoth bones and even feasted on mammoth tongues. Eager to uncover more clues to this mystical prehistoric age, explorers since the time of Peter the Great have scoured Siberia for mammoth remains. Now a new generation of explorers has taken to the tundra. Armed with GPS, ground-penetrating radar, and Soviet-era military helicopters, they seek an elusive prize: a mammoth carcass that will help determine how the creature lived, how it died-and how it might be brought back to life.In this adventure-filled narrative, science writer Richard Stone follows two teams of explorers-one Russian/Japanese, the other a French-led consortium-as they battle bitter cold, high winds, supply shortages, and the deeply rooted superstitions of indigenous peoples who fear the consequences of awakening the "rat beneath the ice." Stone travels from St. Petersburg to the Arctic Circle, from the North Sea to high-tech Japanese laboratories, as he traces the sometimes-surreal quest of these intrepid scientists, whose work could well rewrite our planet's evolutionary history. A riveting tale of high-stakes adventure and scientific hubris, Mammoth is also an intellectual voyage through uncharted moral terrain, as we confront the promise and peril of resurrecting creatures from the deep past.

    In " An Introduction to the Event-Related Potential Technique," Steve Luck offers the first comprehensive guide to the practicalities of conducting ERP experiments in cognitive neuroscience and related fields, including affective neuroscience and experimental psychopathology. The book can serve as a guide for the classroom or the laboratory and as a reference for researchers who do not conduct ERP studies themselves but need to understand and evaluate ERP experiments in the literature. It summarizes the accumulated body of ERP theory and practice, providing detailed, practical advice about how to design, conduct, and interpret ERP experiments, and presents the theoretical background needed to understand why an experiment is carried out in a particular way. Luck focuses on the most fundamental techniques, describing them as they are used in many of the world's leading ERP laboratories. These techniques reflect a long history of electrophysiological recordings and provide an excellent foundation for more advanced approaches.The book also provides advice on the key topic of how to design ERP experiments so that they will be useful in answering questions of broad scientific interest. This reflects the increasing proportion of ERP research that focuses on these broader questions rather than the "ERPology" of early studies, which concentrated primarily on ERP components and methods. Topics covered include the neural origins of ERPs, signal averaging, artifact rejection and correction, filtering, measurement and analysis, localization, and the practicalities of setting up the lab.

    this is one of those rare books that will change your beliefs - and in doing so will change your life. tHE ANt AND tHE FERRARI offers readers a clear, navigable path through the big questions that confront us all today. What is the meaning of life? Can we be ethical beings in today's world? Can we know if there is life after death? Is there such a thing as Absolute truth? What caused the Big Bang and why should you care?

    Poker's biggest players, such as Phil Ivey (2009 WSOP Main Event Finalist), Johnny Chan, Phil Hellmuth, Doyle Brunson and Daniel Negreanu give first-person accounts of their personal journeys and the key moments in their rise to the top of the poker pantheon. These stories will teach, inspire and make you laugh. Deal Me In humanizes the larger-than-life personalities, allowing the reader to understand more about poker strategy through the trials and errors of the best players in the game. Each poker legend tells his or her own story in the book including: Doyle Brunson, Phil Hellmuth, Daniel Negreanu, Phil Ivey, Annie Duke, Johnny Chan, Chris Jesus Ferguson, Carlos Mortensen, Chau Giang, Jennifer Harman, Allen Cunningham, Howard Lederer, Erik Seidel, Chad Brown, David Devilfish Ulliott, Layne Flack, Scotty Nguyen, Annette Obrestad, Tom Dwan and the 2008 Main Event winner Peter Eastgate.

    The top-selling CS review book written by students and IMGs who recently passed 100+ high-yield minicases by chief complaint 30 complete cases simulate the exam experience Contains new Patient Encounters, including telephone interviews Perfect for group or solo study YOUR COMPLETE CS SURVIVAL GUIDE FROM THE AUTHORS OF FIRST AID FOR THE USMLE STEP 1 INSIDER ADVICE FOR STEP 2 CS SUCCESS New miniguide shows US students and IMGs how best to use this book Revised by test veterans to reflect the 2005--2006 exam experience Each complete case features standardized patient checklists and a recommended clinical approach Minicases represent the major chief complaints and diagnoses seen on the Step 2 CS Proven strategies for the patient encounter and patient note High-yield, must-know facts on patient diagnosis and workup.

    Still, many wonder what foods they should be eating for best results. Is there one best diet that works for every one of us? The surprising answer to that question is an emphatic NO! In Feast Without Fear, the follow up to Delay, Don't Deny, you will learn what makes each of us unique, and why there is not a one-size-fits-all approach, no matter what all of the diet books promise you. From your genetic differences to your individual gut microbiome, there are personal factors that affect how your body responds to the foods you eat. In addition, you will examine several well-researched dietary approaches that are linked to vibrant health and longevity. You will discover how to craft an individual eating style that makes you feel your very best, while still eating the foods you love. Get ready to Feast Without Fear!

    It is written to impart a sense of intellectual history of biochemistry, an understanding of the tools and approaches used to solve biochemical puzzles, and a hint of the excitement that accompanies new discoveries. This edition has been thoroughly updated to reflect the most recent advances in biochemistry, particularly in the areas of genomics and structural biology. A new chapter focuses on cytoskeletal and motor proteins, currently one of the most active areas of research in biochemistry.

    This book was originally written by third-year medical students searching for the perfect review book--not finding it on the market, they wrote it themselves! Now in its third edition, Step-Up to Medicine boils down the full scope of tested pathology in a single ingenious tool. Each element is tailored for immediate content absorption, and an all-new, full-color interior differentiate elements for even faster, more efficient review. And, Step-Up to Medicine , third edition provides two types of self-assessment--the kinds of questions you will ask yourself as a clinician plus USMLE-style practice questions. This review book gives you just the Step-Up to the medicine clerkship, accompanying shelf exams, and USMLE Step 2 that you need! NEW Features for this blockbuster edition: Full-color, updated interior design brings the content to you in a rousing, memorable style. Full-color, updated art program illustrates concepts when a picture says it best--plenty of clinical images also supplement topics. New content on evidence-based medicine keeps you current and informed to guide your clinical decision making. Expanded content on drug dosing is added where relevant.CLASSIC Features students swear by: Complete coverage of high-yield medical topics ensures you are test ready Clinical Pearls boxes help you "file away" clinical medicine connections for handy retrieval at test time Quick Hits glimmering in the margins highlight highly testable material--just see how the sparks fly at test timeBONUS Material and study resources: eBook with the fully searchable text is available via thePoint . NEW 300 USMLE-style questions provide another means of self-assessment and practice for those exams NEW Audio clips of breath and heart sounds also available on thePoint