However, scant attention has been paid to the two women who were closest to him: Renee Pelagie de Sade, his adoring wife, and his powerful mother-in-law, Madame de Montreuil.Francine du Plessix Gray draws on thousands of pages of letters exchanged by the married couple, few of which have been published before in English, to explore in the fullest historical and psychological detail what it was like to be married to one of the most maverick spirits of modern history. Gray brings to life two remarkable women and their complex relationship to Sade as they dedicated themselves to protecting him from the law, curbing his excesses, and ultimately confining him. With immediacy, irony, and verve, At Home with the Marquis de Sade also conjures up the extravagant hedonism and terror of late eighteenth-century France.

    The Sackler name adorns the walls of many storied institutions: Harvard, the Metropolitan Museum of Art, Oxford, the Louvre. They are one of the richest families in the world, known for their lavish donations to the arts and sciences. The source of the family fortune was vague, however, until it emerged that the Sacklers were responsible for making and marketing OxyContin, a blockbuster painkiller that was a catalyst for the opioid crisis.Empire of Pain is a masterpiece of narrative reporting and writing, exhaustively documented and ferociously compelling.

    Among all aspects of Jefferson's renowned life, it was perhaps the most hotly contested topic. The publication of Thomas Jefferson and Sally Hemings intensified this debate by identifying glaring inconsistencies in many noted scholars' evaluations of the existing evidence. In this study, Gordon-Reed assembles a fascinating and convincing argument: not that the alleged thirty-eight-year liaison necessarily took place but rather that the evidence for its taking place has been denied a fair hearing.Friends of Jefferson sought to debunk the Hemings story as early as 1800, and most subsequent historians and biographers followed suit, finding the affair unthinkable based upon their view of Jefferson's life, character, and beliefs. Gordon-Reed responds to these critics by pointing out numerous errors and prejudices in their writings, ranging from inaccurate citations, to impossible time lines, to virtual exclusions of evidence--especially evidence concerning the Hemings family. She demonstrates how these scholars may have been misguided by their own biases and may even have tailored evidence to serve and preserve their opinions of Jefferson. This updated edition of the book also includes an afterword in which the author comments on the DNA study that provided further evidence of a Jefferson and Hemings liaison.Possessing both a layperson's unfettered curiosity and a lawyer's logical mind, Annette Gordon-Reed writes with a style and compassion that are irresistible. Each chapter revolves around a key figure in the Hemings drama, and the resulting portraits are engrossing and very personal. Gordon-Reed also brings a keen intuitive sense of the psychological complexities of human relationships--relationships that, in the real world, often develop regardless of status or race. The most compelling element of all, however, is her extensive and careful research, which often allows the evidence to speak for itself. Thomas Jefferson and Sally Hemings: An American Controversy is the definitive look at a centuries-old question that should fascinate general readers and historians alike.

    Braided with that history is the moving story of Powers's beloved son Kevin--spirited, endearing, and gifted--who triumphed even while suffering from schizophrenia until finally he did not, and the story of his courageous surviving son Dean, who is also schizophrenic.A blend of history, biography, memoir, and current affairs ending with a consideration of where we might go from here, this is a thought-provoking look at a dreaded illness that has long been misunderstood.

    In her perceptive introduction to this edition, Irene Diggs sets this classic autobiography against its broad historical context and critically analyzes its theoretical and methodological significance.

    America faced a troubling question: What happened? How was this epidemic allowed to spread so far before it was taken seriously? In answering these questions, Shilts weaves the disparate threads into a coherent story, pinning down every evasion and contradiction at the highest levels of the medical, political, and media establishments. Shilts shows that the epidemic spread wildly because the federal government put budget ahead of the nation's welfare; health authorities placed political expediency before the public health; and scientists were often more concerned with international prestige than saving lives. Against this backdrop, Shilts tells the heroic stories of individuals in science and politics, public health and the gay community, who struggled to alert the nation to the enormity of the danger it faced. And the Band Played On is both a tribute to these heroic people and a stinging indictment of the institutions that failed the nation so badly.

    She explores the culture of genealogy buffs, the science of DNA, and the business of companies like Ancestry and 23andMe, all while tracing the story of one woman, her unusual results, and a relentless methodical drive for answers that becomes a thoroughly modern genetic detective story.

    Bennet Omalu, the pathologist who made one of the most significant medical discoveries of the twenty-first century, a discovery that challenges the existence of America’s favorite sport and puts Omalu in the crosshairs of football’s most powerful corporation: the NFL. Jeanne Marie Laskas first met the young forensic pathologist Dr. Bennet Omalu in 2009, while reporting a story for GQ that would go on to inspire the movie Concussion. Omalu told her about a day in September 2002, when, in a dingy morgue in downtown Pittsburgh, he picked up a scalpel and made a discovery that would rattle America in ways he’d never intended. Omalu was new to America, chasing the dream, a deeply spiritual man escaping the wounds of civil war in Nigeria. The body on the slab in front of him belonged to a fifty-year-old named Mike Webster, aka “Iron Mike,” a Hall of Fame center for the Pittsburgh Steelers, one of the greatest ever to play the game. After retiring in 1990, Webster had suffered a dizzyingly steep decline. Toward the end of his life, he was living out of his van, tasering himself to relieve his chronic pain, and fixing his rotting teeth with Super Glue. How did this happen?, Omalu asked himself. How did a young man like Mike Webster end up like this? The search for answers would change Omalu’s life forever and put him in the crosshairs of one of the most powerful corporations in America: the National Football League. What Omalu discovered in Webster’s brain—proof that Iron Mike’s mental deterioration was no accident but a disease caused by blows to the head that could affect everyone playing the game—was the one truth the NFL wanted to ignore.   Taut, gripping, and gorgeously told, Concussion is the stirring story of one unlikely man’s decision to stand up to a multibillion-dollar colossus, and to tell the world the truth.  Advance praise for Concussion “A gripping medical mystery and a dazzling portrait of the young scientist no one wanted to listen to . . . a fabulous, essential read.”—Rebecca Skloot, author of The Immortal Life of Henrietta Lacks“The story of Dr. Bennet Omalu’s battle against the NFL is classic David and Goliath stuff, and Jeanne Marie Laskas—one of my favorite writers on earth—makes it as exciting as any great courtroom or gridiron drama. A riveting, powerful human tale—and a master class on how to tell a story.”—Charles Duhigg, author of The Power of Habit   “Bennet Omalu forced football to reckon with head trauma. The NFL doesn’t want you to hear his story, but Jeanne Marie Laskas makes it unforgettable. This book is gripping, eye-opening, and full of heart.”—Emily Bazelon, author of Sticks and Stones

    It yields an extraordinary account of the rise and fall of Purgatory as both a belief and a lucrative institution--as well as a capacious new reading of the power of Hamlet.In the mid-sixteenth century, English authorities abruptly changed the relationship between the living and dead. Declaring that Purgatory was a false poem, they abolished the institutions and banned the practices that Christians relied on to ease the passage to Heaven for themselves and their dead loved ones. Greenblatt explores the fantastic adventure narratives, ghost stories, pilgrimages, and imagery by which a belief in a grisly prison house of souls had been shaped and reinforced in the Middle Ages. He probes the psychological benefits as well as the high costs of this belief and of its demolition.With the doctrine of Purgatory and the elaborate practices that grew up around it, the church had provided a powerful method of negotiating with the dead. The Protestant attack on Purgatory destroyed this method for most people in England, but it did not eradicate the longings and fears that Catholic doctrine had for centuries focused and exploited. In his strikingly original interpretation, Greenblatt argues that the human desires to commune with, assist, and be rid of the dead were transformed by Shakespeare--consummate conjurer that he was--into the substance of several of his plays, above all the weirdly powerful Hamlet. Thus, the space of Purgatory became the stage haunted by literature's most famous ghost.This book constitutes an extraordinary feat that could have been accomplished by only Stephen Greenblatt. It is at once a deeply satisfying reading of medieval religion, an innovative interpretation of the apparitions that trouble Shakespeare's tragic heroes, and an exploration of how a culture can be inhabited by its own spectral leftovers.

    When we weren't sheltering in place, we were advised to wear masks, wash our hands, and practice social distancing. We watched in horror as medical personnel worked around the clock to care for the sick and dying. Businesses were shuttered, travel stopped, workers were furloughed, and markets dropped. And people continued to die.Amid all this uncertainty, writers and artists from around the world continued to create comics, commenting directly on how individuals, societies, governments, and markets reacted to the worldwide crisis. COVID Chronicles: A Comics Anthology collects more than sixty such short comics from a diverse set of creators, including indie powerhouses, mainstream artists, Ignatz and Eisner Award winners, and media cartoonists. In narrative styles ranging from realistic to fantastic, they tell stories about adjusting to working from home, homeschooling their kids, missing birthdays and weddings, and being afraid just to leave the house. They probe the failures of government leaders and the social safety net. They dig into the racial bias and systemic inequities that this pandemic helped bring to light. We see what it's like to get the virus and live to tell about it, or to stand by helplessly as a loved one passes.At times heartbreaking and at others hopeful and humorous, these comics express the anger, anxiety, fear, and bewilderment we feel in the era of COVID-19. Above all, they highlight the power of art and community to help us make sense of a world in crisis, reminding us that we are truly all in this together.The comics in this collection have been generously donated by their creators. A portion of the the proceeds from the sale of this volume are being donated by the publisher to the Book Industry Charitable Foundation (Binc) in support of comics shops, bookstores, and their employees who have been adversely affected by the pandemic.

    . . when it comes to the legacy of this country's war on drugs, we should all share his outrage." --The New York Times Book Review From one of the world's foremost experts on the subject, a powerful argument that the greatest damage from drugs flows from their being illegal, and a hopeful reckoning with the possibility of their use as part of a responsible and happy lifeDr. Carl L. Hart, Ziff Professor at Columbia University and former chair of the Department of Psychology, is one of the world's preeminent experts on the effects of so-called recreational drugs on the human mind and body. Dr. Hart is open about the fact that he uses drugs himself, in a happy balance with the rest of his full and productive life as a colleague, husband, father, and friend. In Drug Use for Grown-Ups, he draws on decades of research and his own personal experience to argue definitively that the criminalization and demonization of drug use--not drugs themselves--have been a tremendous scourge on America, not least in reinforcing this country's enduring structural racism.Dr. Hart did not always have this view. He came of age in one of Miami's most troubled neighborhoods at a time when many ills were being laid at the door of crack cocaine. His initial work as a researcher was aimed at proving that drug use caused bad outcomes. But one problem kept cropping up: the evidence from his research did not support his hypothesis. From inside the massively well-funded research arm of the American war on drugs, he saw how the facts did not support the ideology. The truth was dismissed and distorted in order to keep fear and outrage stoked, the funds rolling in, and Black and brown bodies behind bars.Drug Use for Grown-Ups will be controversial, to be sure: the propaganda war, Dr. Hart argues, has been tremendously effective. Imagine if the only subject of any discussion about driving automobiles was fatal car crashes. Drug Use for Grown-Ups offers a radically different vision: when used responsibly, drugs can enrich and enhance our lives. We have a long way to go, but the vital conversation this book will generate is an extraordinarily important step.

    In this book, Christine Overall maintains that the burden of proof should be reversed: that the choice to have children calls for more careful justification and reasoning than the choice not to. Arguing that the choice to have children is not just a prudential or pragmatic decision but one with ethical repercussions, Overall offers a wide-ranging exploration of how we might think systematically and deeply about this fundamental aspect of human life. Writing from a feminist perspective, she also acknowledges the inevitably gendered nature of the decision; although both men and women must ponder the issue, the choice has different meanings, implications, and risks for women than it has for men. Overall considers a series of ethical perspectives on procreation, examining approaches that rely on reproductive rights; on fundamental religious, family, or political values; and on the anticipated consequences of the decision for both individuals and society. She examines some of the broader issues relevant to the decision, including population growth, resource depletion, and social policies governing reproduction. Finding the usual approaches to the question inadequate or incomplete, she offers instead a novel argument. Exploring the nature of the biological parent-child relationship--which is not only genetic but also psychological, physical, intellectual, and moral--she argues that the formation of that relationship is the best possible reason for choosing to have a child.

    Months later, several health professionals faced criminal allegations that they deliberately injected numerous patients with drugs to hasten their deaths. Five Days at Memorial, the culmination of six years of reporting, unspools the mystery of what happened in those days, bringing the reader into a hospital fighting for its life and into a conversation about the most terrifying form of health care rationing.In a voice at once involving and fair, masterful and intimate, Fink exposes the hidden dilemmas of end-of-life care and reveals just how ill-prepared we are in America for the impact of large-scale disasters—and how we can do better. A remarkable book, engrossing from start to finish, Five Days at Memorial radically transforms your understanding of human nature in crisis.

    But, as God's Own Party demonstrates, they shouldn't have been. The Christian Right goes back much farther than most journalists, political scientists, and historians realize. Relying onextensive archival and primary source research, Daniel K. Williams presents the first comprehensive history of the Christian Right, uncovering how evangelicals came to see the Republican Party as the vehicle through which they could reclaim America as a Christian nation. A fascinating andmuch-needed account of a key force in American politics, God's Own Party is the only full-scale analysis of the electoral shifts, cultural changes, and political activists at the movement's core--showing how the Christian Right redefined politics as we know it.

    But New Yorkers don't give it much attention. They leave their trash on the curb or drop it in a litter basket, and promptly forget about it. And why not? On a schedule so regular you could almost set your watch by it, someone always comes to take it away.But who, exactly, is that someone? And why is he—or she—so unknown?In Picking Up, the anthropologist Robin Nagle introduces us to the men and women of New York City's Department of Sanitation and makes clear why this small army of uniformed workers is the most important labor force on the streets. Seeking to understand every aspect of the Department's mission, Nagle accompanied crews on their routes, questioned supervisors and commissioners, and listened to story after story about blizzards, hazardous wastes, and the insults of everyday New Yorkers. But the more time she spent with the DSNY, the more Nagle realized that observing wasn't quite enough—so she joined the force herself. Driving the hulking trucks, she obtained an insider's perspective on the complex kinships, arcane rules, and obscure lingo unique to the realm of sanitation workers.Nagle chronicles New York City's four-hundred-year struggle with trash, and traces the city's waste-management efforts from a time when filth overwhelmed the streets to the far more rigorous practices of today, when the Big Apple is as clean as it's ever been.Throughout, Nagle reveals the many unexpected ways in which sanitation workers stand between our seemingly well-ordered lives and the sea of refuse that would otherwise overwhelm us. In the process, she changes the way we understand cities—and ourselves within them.