At his death last spring, Roueche left behind seven new narratives that have never been published in book form. This book collects these works along with one earlier classic--all relating true tales of strange illnesses, rare diseases, and the brilliant minds who race to understand and conquer them.

    Brinkley–America’s most brazen young con man–arrived in the tiny town of Milford, Kansas. He set up a medical practice and introduced an outlandish surgical method using goat glands to restore the fading virility of local farmers.It was all nonsense, of course, but thousands of paying customers quickly turned “Dr.” Brinkley into America’s richest and most famous surgeon. His notoriety captured the attention of the great quackbuster Morris Fishbein, who vowed to put the country’s “most daring and dangerous” charlatan out of business.Their cat-and-mouse game lasted throughout the 1920s and ’30s, but despite Fishbein’s efforts Brinkley prospered wildly. When he ran for governor of Kansas, he invented campaigning techniques still used in modern politics. Thumbing his nose at American regulators, he built the world’s most powerful radio transmitter just across the Rio Grande to offer sundry cures, and killed or maimed patients by the score, yet his warped genius produced innovations in broadcasting that endure to this day. By introducing country music and blues to the nation, Brinkley also became a seminal force in rock ’n’ roll. In short, he is the most creative criminal this country has ever produced.Culminating in a decisive courtroom confrontation that pit Brinkley against his nemesis Fishbein, Charlatan is a marvelous portrait of a boundlessly audacious rogue on the loose in an America that was ripe for the bamboozling.

    The tycoon had close ties to the U.S. government, and he soon asked Elizebeth to apply her language skills to an exciting new venture: code-breaking. There she met the man who would become her husband, groundbreaking cryptologist William Friedman. In The Woman Who Smashed Codes, Jason Fagone chronicles the life of Elizebeth Smith who played an integral role in our nation's history for forty years. After World War I, Smith used her talents to catch gangsters and smugglers during Prohibition, then accepted a covert mission to discover and expose Nazi spy rings that were spreading like wildfire across South America, advancing ever closer to the United States. As World War II raged, Elizebeth fought a highly classified battle of wits against Hitler's Reich, cracking multiple versions of the Enigma machine used by German spies. Meanwhile, inside an Army vault in Washington, William worked furiously to break Purple, the Japanese version of Enigma--and eventually succeeded, at a terrible cost to his personal life.Fagone unveils America's code-breaking history through the prism of Smith's life, bringing into focus the unforgettable events and colorful personalities that would help shape modern intelligence.

    Bush describes the critical decisions that shaped his presidency and personal life.George W. Bush served as president of the United States during eight of the most consequential years in American history. The decisions that reached his desk impacted people around the world and defined the times in which we live.Decision Points brings readers inside the Texas governor’s mansion on the night of the 2000 election, aboard Air Force One during the harrowing hours after the attacks of September 11, 2001, into the Situation Room moments before the start of the war in Iraq, and behind the scenes at the White House for many other historic presidential decisions.For the first time, we learn President Bush’s perspective and insights on:His decision to quit drinking and the journey that led him to his Christian faithThe selection of the vice president, secretary of defense, secretary of state, Supreme Court justices, and other key officialsHis relationships with his wife, daughters, and parents, including heartfelt letters between the president and his father on the eve of the Iraq WarHis administration’s counterterrorism programs, including the CIA’s enhanced interrogations and the Terrorist Surveillance ProgramWhy the worst moment of the presidency was hearing accusations that race played a role in the federal government’s response to Hurricane Katrina, and a critical assessment of what he would have done differently during the crisisHis deep concern that Iraq could turn into a defeat costlier than Vietnam, and how he decided to defy public opinion by ordering the troop surgeHis legislative achievements, including tax cuts and reforming education and Medicare, as well as his setbacks, including Social Security and immigration reformThe relationships he forged with other world leaders, including an honest assessment of those he did and didn’t trustWhy the failure to bring Osama bin Laden to justice ranks as his biggest disappointment and why his success in denying the terrorists their fondest wish—attacking America again—is among his proudest achievementsA groundbreaking new brand of presidential memoir, Decision Points will captivate supporters, surprise critics, and change perspectives on eight remarkable years in American history—and on the man at the center of events.

    With the same eye for drama and humor that Corson brings to the exploits of the chefs, he delves into the biology and natural history of the creatures of the sea. He illuminates sushi's beginnings as an Indo-Chinese meal akin to cheese, describes its reinvention in bustling nineteenth-century Tokyo as a cheap fast food, and tells the story of the pioneers who brought it to America. He shows how this unlikely meal is now exploding into the American heartland just as the long-term future of sushi may be unraveling.The Zen of Fish is a compelling tale of human determination as well as a delectable smorgasbord of surprising food science, intrepid reporting, and provocative cultural history.

    Building a house would entail no more work than planting a seed in the ground. These scenarios may seem far-fetched, but pioneering geneticist George Church and science writer Ed Regis show that synthetic biology is bringing us ever closer to making such visions a reality. In Regenesis, Church and Regis explore the possibilities—and perils—of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. Until now, nature has been the exclusive arbiter of life, death, and evolution; with synthetic biology, we now have the potential to write our own biological future. Indeed, as Church and Regis show, it even enables us to revisit crucial points in the evolution of life and, through synthetic biological techniques, choose different paths from those nature originally took. Such exploits will involve far more than just microbial tinkering. Full-blown genomic engineering will make possible incredible feats, from resurrecting woolly mammoths and other extinct organisms to creating mirror life forms with a molecular structure the opposite of our own. These technologies—far from the out-of-control nightmare depicted in science fiction—have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span. A breathtaking look at the potential of this world-changing technology, Regenesis is nothing less than a guide to the future of life.

    Rather, they recruited an elite group of young women who, with only pencil, paper, and mathematical prowess, transformed rocket design, helped bring about the first American satellites, and made the exploration of the solar system possible. For the first time, Rise of the Rocket Girls tells the stories of these women--known as "human computers"--who broke the boundaries of both gender and science. Based on extensive research and interviews with all the living members of the team, Rise of the Rocket Girls offers a unique perspective on the role of women in science: both where we've been, and the far reaches of space to which we're heading.

    From the values Madoff was taught growing up in the working class town of Laurelton, Queens to his high-life on Wall Street and the super-rich enclaves of Palm Beach and the French Riviera, bestselling author Jerry Oppenheimer follows the disgraced money manager's trail as he works his way up the social and economic ladder, and eventually scams his trusting clients in a $50 billion Ponzi scheme.Through Oppenheimer's in-depth reporting, you'll discover new revelations in this startling case, and become familiar with the trusting victims-ranging from non-profit Jewish charities to the likes of seemingly sophisticated individuals such as actress Jane Fonda who would "like to shake Madoff until his teeth fall out," the scion of the Baskin-Robbins ice cream empire who lost a bundle and was forced to rent out rooms in his house, and New Jersey Senator Frank Lautenberg. There's even Madoff's own sister-in-law and talk show host Larry King, who apparently didn't ask the right questions when he invested. All lost their much-needed life savings, while others saw fortunes small and large evaporate in the greedy financial operations of one of history's all-time charlatans.Madoff With the MoneyDelves into the details of the illusive man that lost investors billions Weaves stories of Madoff's past with those of the present in an engaging and accessible style Explores how the financial scam that Madoff ran cost individuals and institutions billions of dollars Other titles by Oppenheimer: Toy Monster: The Big, Bad World of Mattel, and Just Desserts: Martha Stewart the Unauthorized BiographyWhile there may be other books on the Bernie Madoff debacle, none digs as deep or goes as far to uncover the truth behind the man, and his incredible scam.

    In How to Clone a Mammoth, Beth Shapiro, evolutionary biologist and pioneer in "ancient DNA" research, walks readers through the astonishing and controversial process of de-extinction. From deciding which species should be restored, to sequencing their genomes, to anticipating how revived populations might be overseen in the wild, Shapiro vividly explores the extraordinary cutting-edge science that is being used--today--to resurrect the past. Journeying to far-flung Siberian locales in search of ice age bones and delving into her own research--as well as those of fellow experts such as Svante Paabo, George Church, and Craig Venter--Shapiro considers de-extinction's practical benefits and ethical challenges. Would de-extinction change the way we live? Is this really cloning? What are the costs and risks? And what is the ultimate goal?Using DNA collected from remains as a genetic blueprint, scientists aim to engineer extinct traits--traits that evolved by natural selection over thousands of years--into living organisms. But rather than viewing de-extinction as a way to restore one particular species, Shapiro argues that the overarching goal should be the revitalization and stabilization of contemporary ecosystems. For example, elephants with genes modified to express mammoth traits could expand into the Arctic, re-establishing lost productivity to the tundra ecosystem.Looking at the very real and compelling science behind an idea once seen as science fiction, How to Clone a Mammoth demonstrates how de-extinction will redefine conservation's future.

    Sixteen weeks later, Frank Borman, Jim Lovell, and Bill Anders were aboard the first manned spacecraft to depart Earth’s orbit, reach the moon, and return safely to Earth, delivering a tear-inducing Christmas Eve message along the way.

    She conjures up early operating theaters--no place for the squeamish--and surgeons, working before anesthesia, who were lauded for their speed and brute strength. These medical pioneers knew that the aftermath of surgery was often more dangerous than their patients' afflictions, and they were baffled by the persistent infections that kept mortality rates stubbornly high. At a time when surgery couldn't have been more hazardous, an unlikely figure stepped forward: a young, melancholy Quaker surgeon named Joseph Lister, who would solve the deadly riddle and change the course of history.Fitzharris dramatically recounts Lister's discoveries in gripping detail, culminating in his audacious claim that germs were the source of all infection--and could be countered by antiseptics. Focusing on the tumultuous period from 1850 to 1875, she introduces us to Lister and his contemporaries--some of them brilliant, some outright criminal--and takes us through the grimy medical schools and dreary hospitals where they learned their art, the deadhouses where they studied anatomy, and the graveyards they occasionally ransacked for cadavers.Eerie and illuminating, The Butchering Art celebrates the triumph of a visionary surgeon whose quest to unite science and medicine delivered us into the modern world.

    Here he recounts in his inimitable voice his experience trading ideas on atomic physics with Einstein and Bohr and ideas on gambling with Nick the Greek; cracking the uncrackable safes guarding the most deeply held nuclear secrets; accompanying a ballet on his bongo drums; painting a naked female toreador. In short, here is Feynman's life in all its eccentric—a combustible mixture of high intelligence, unlimited curiosity, and raging chutzpah.

    Willie Parker grew up in the Deep South, lived in a Christian household, and converted to an even more fundamentalist form of Christianity as a young man. But upon reading an interpretation of the Good Samaritan in a sermon by Dr. Martin Luther King, Jr., he realized that in order to be a true Christian, he must show compassion for all women regardless of their needs. In 2009, he stopped practicing obstetrics to focus entirely on providing safe abortions for the women who need help the most—often women in poverty and women of color—and in the hot bed of the pro-choice debate: the South. He soon thereafter traded in his private practice and his penthouse apartment in Hawaii for the life of an itinerant abortion provider, focusing most recently on women in the Deep South. In Life’s Work, Dr. Willie Parker tells a deeply personal and thought-provoking narrative that illuminates the complex societal, political, religious, and personal realities of abortion in the United States from the unique perspective of someone who performs them and defends the right to do so every day. He also looks at how a new wave of anti-abortion activism, aimed at making incremental changes in laws and regulations state by state, are slowly chipping away at the rights of women to control their own lives. In revealing his daily battle against mandatory waiting periods and bogus rules governing the width of hallways, Dr. Parker uncovers the growing number of strings attached to the right to choose and makes a powerful Christian case for championing reproductive rights.

    What they don’t know is her trailblazing career was a happy accident. In this funny and intimate memoir, Penny takes us from the stage of The Jackie Gleason Show in 1955 to Hollywood’s star-studded sets, offering up some hilarious detours along the way.My Mother Was Nuts is an intimate backstage pass to Penny’s personal life, her breakout role on The Odd Couple, her exploits with Cindy Williams and John Belushi, and her travels across Europe with Art Garfunkel on the back of a motorcycle. We see Penny get married. And divorced. And married again (the second time to Rob Reiner). We meet a young Carrie Fisher, whose close friendship with Penny has spanned decades. And we see Penny at work with Tom Hanks, Mark Wahlberg, Whoopi Goldberg, Robert De Niro, and Whitney Houston.Throughout it all, from her childhood spent tap dancing in the Bronx, to her rise as the star of Laverne & Shirley, Penny lived by simple rules: “try hard, help your friends, don’t get too crazy, and have fun.” With humor and heart, My Mother Was Nuts reveals there’s no one else quite like Penny Marshall.

     Giving shape to the deep depression that pervaded Lincoln's adult life, Joshua Wolf Shenk's Lincoln's Melancholy reveals how this illness influenced both the president's character and his leadership. Lincoln forged a hard path toward mental health from the time he was a young man. Shenk draws from historical record, interviews with Lincoln scholars, and contemporary research on depression to understand the nature of his unhappiness. In the process, he discovers that the President's coping strategies—among them, a rich sense of humor and a tendency toward quiet reflection—ultimately helped him to lead the nation through its greatest turmoil.