Few people know much about stem cell research beyond the ethical questions raised by using embryos. But in the last decade, stem cell research has made huge advances toward eliminating some of our most intractable diseases. Now this sweeping and accessible book introduces us to this cutting-edge science that will revolutionize medicine and change the way we think about and treat disease. Alice Park takes us from stem cell's controversial beginnings to the recent electrifying promise of being able to create the versatile cells without using embryos at all. She shows us how stem cells give researchers an unprecedented ability to study disease while giving patients the promise of replacing diseased cells with healthy new ones. And she profiles the scientists and leaders-many with their own compelling stories-who have fueled the quest and will continue to shape the field in years to come.

    Much as Brainiac offered a behind-the-scenes look at the little-known demimonde of competitive trivia buffs, Maphead finally gives equal time to that other downtrodden underclass: America's map nerds.In a world where geography only makes the headlines when college students are (endlessly) discovered to be bad at it, these hardy souls somehow thrive. Some crisscross the map working an endless geographic checklist: visiting all 3,143 U.S. counties, for example, or all 936 UNESCO World Heritage Sites. Some pore over million-dollar collections of the rarest maps of the past; others embrace the future by hunting real-world cartographic treasures like "geocaches" or "degree confluences" with GPS device in hand. Some even draw thousands of their own imaginary maps, lovingly detailing worlds that never were.Ken Jennings was a map nerd from a young age himself, you will not be surprised to learn, even sleeping with a bulky Hammond atlas at the side of his pillow, in lieu of the traditional Teddy bear. As he travels the nation meeting others of his tribe--map librarians, publishers, "roadgeeks," pint-sized National Geographic Bee prodigies, the computer geniuses behind Google Maps and other geo-technologies--he comes to admire these geographic obsessives. Now that technology and geographic illiteracy are increasingly insulating us from the lay of the land around us, we are going to be needing these people more than ever. Mapheads are the ones who always know exactly where they are--and where everything else is as well.

    Tedford have spent the past 20 years studying the evolutionary history of the family Canidae. Both are well known for having established the modern framework for the evolutionary relationship of canids. Combining their research with Mauricio Ant�n's impeccable reconstructions of both extinct and extant species, Wang and Tedford present a remarkably detailed and nuanced portrait of the origin and evolution of canids over the past 40 million years.The authors cull their history from the most recent scientific research conducted on the vast collections of the American Museum of Natural History and other leading institutions. The fossil record of the Canidae, particularly those from their birth place in North America, are the strongest of their kind among known groups of carnivorans. Such a wonderfully detailed evolutionary history provides access to a natural history that is not possible with many other groups of carnivorans.With their rich fossil record, diverse adaptations to various environments, and different predatory specializations, canids are an ideal model organism for the mapping of predator behavior and morphological specializations. They also offer an excellent contrast to felids, which remain entrenched in extreme predatory specializations. The innovative illustrated approach in this book is the perfect accompaniment to an extremely important branch of animal and fossil study. It transforms the science of paleontology into a thrilling visual experience and provides an unprecedented reference for anyone fascinated by dogs.

    It covers 3,000 years of history from the city’s quasi-mythical origins, through the Etruscan kings, the opulent glory of classical Rome, the decadence and decay of the Middle Ages and the beauty and corruption of the Renaissance, to its time at the heart of Mussolini’s fascist Italy. Exploring the city’s streets and buildings, peopled with popes, gladiators, emperors, noblemen and peasants, this volume details the turbulent and dramatic history of Rome in all its depravity and grandeur.

    With this revised edition, Wilford brings the story up to the present day, as he shows the impact of new technologies that make it possible for cartographers to go where no one has been before, from the deepest reaches of the universe (where astronomers are mapping time as well as space) to the inside of the human brain. These modern-day mapmakers join the many earlier adventurers–including ancient Greek stargazers, Renaissance seafarers, and the explorers who mapped the American West–whose exploits shape this dramatic story of human inventiveness and limitless curiosity.

    He had already proved that you could see the world without a dime in your pocket, and have a whale of a time doing it. Yet after various adventures on land and by sea, America's most dashing traveler decided there was only path left open for him - the sky itself. "The Flying Carpet" was Halliburton's fourth and most famous book and details his epic adventures flying a bi-plane through remote parts of the globe. It recounts how Halliburton landed in Timbuctoo, passed over Mt. Everest, flew over the Taj Mahal upside down, and dropped down into the jungles of Borneo to visit native head hunters. "Stephens," Halliburton told the pilot, "I've just given myself an airplane and I want you to fly us to all the outlandish places in the world, Turkey, Persia, Paris and - Pasadena. We're going to fly across deserts, over mountains, rescue imprisoned princesses and fight dragons. We must have the world. We can have the world!" If one book can summarize all the reckless love of life and romance that symbolized Richard Halliburton, then this is the book.

    Illustrated in full colour.

    Robert Oppenheimer rode out his political persecution in the Director's mansion. It is the Institute for Advanced Study in Princeton, New Jersey; at one time or another, home to fourteen Nobel laureates, most of the great physicists and mathematicians of the modern era, and two of the most exciting developments in twentieth-century science—cellular automata and superstrings.Who Got Einstein's Office? tells for the first time the story of this secretive institution and of its fascinating personalities.

    The linear metaphor is ubiquitous in everyday visual representations of time—in almanacs, calendars, charts, and graphs of all sorts. Even our everyday speech is filled with talk of time having a "before" and an "after" or being "long" and "short." The timeline is such a familiar part of our mental furniture that it is sometimes hard to remember that we invented it in the first place. And yet, in its modern form, the timeline is not even 250 years old. The story of what came before has never been fully told, until now. Cartographies of Time is the first comprehensive history of graphic representations of time in Europe and the United States from 1450 to the present. Authors Daniel Rosenberg and Anthony Grafton have crafted a lively history featuring fanciful characters and unexpected twists and turns. From medieval manuscripts to websites, Cartographies of Time features a wide variety of timelines that in their own unique ways—curving, crossing, branching—defy conventional thinking about the form. A fifty-four-foot-long timeline from 1753 is mounted on a scroll and encased in a protective box. Another timeline uses the different parts of the human body to show the genealogies of Jesus Christ and the rulers of Saxony. Ladders created by missionaries in eighteenth-century Oregon illustrate Bible stories in a vertical format to convert Native Americans. Also included is the April 1912 Marconi North Atlantic Communication chart, which tracked ships, including the Titanic, at points in time rather than by theirgeographic location, alongside little-known works by famous figures, including a historical chronology by the mapmaker Gerardus Mercator and a chronological board game patented by Mark Twain. Presented in a lavishly illustrated edition, Cartographies of Time is a revelation to anyone interested in the role visual forms have played in our evolving conception of history.

    Yet for Andrea Doria, the Admiral of the King of France, he soon learns that the battles he confronts are not confined to sea alone. The House of Dorian is plagued with conflict, both within and without, and Andrea finds that he has very real enemies in his midst.

    Boosters of the city have long capitalized on this splendor, recently likening it to the fairytale capital of L. Frank Baum’s The Wizard of Oz, the Emerald City. But just as Dorothy, Toto, and their traveling companions discover a darker reality upon entering the green gates of the imaginary Emerald City, those who look more closely at Seattle’s landscape will find that it reveals a history marked by environmental degradation and urban inequality.This book explores the role of nature in the development of the city of Seattle from the earliest days of its settlement to the present. Combining environmental history, urban history, and human geography, Matthew Klingle shows how attempts to reshape nature in and around Seattle have often ended not only in ecological disaster but also social inequality. The price of Seattle’s centuries of growth and progress has been paid by its wildlife, including the famous Pacific salmon, and its poorest residents. Klingle proposes a bold new way of understanding the interdependence between nature and culture, and he argues for what he calls an “ethic of place.” Using Seattle as a compelling case study, he offers important insights for every city seeking to live in harmony with its natural landscape.

    He traveled the world in order to find things that no one else had seen—but what did he really discover? The stories that he told upon his return to his homeland of the Republic of Venice were so unusual that his fellow compatriots often had a hard time believing him. When he described things such as paper money, gun powder, and coal, these were still so far out of the daily routine of the west that they seemed utterly bizarre to his contemporaries.But even now that Marco Polo’s discoveries are less exotic and more commonplace, do we truly understand what it was that he uncovered? This book will delve deep into the life and legend of Marco Polo.

    The posthumous influence of the Roman Republic and Empire have no equal in all of history. Their varied culture, stunning art, brilliant philosophy, and towering architecture is embedded in our modern world. Roman innovation has left behind a legacy that has remained admired and emulated for over a thousand years. They built massive networks of roads before the birth of Christ. They constructed elaborate public sewer systems over 1,500 years before the United States became a Nation, and had networks of aqueducts bringing running water. Their tactics in battle are still studied by historians and military leaders of today. Their history is filled with great conflicts, compelling love stories, and the most treacherous of leaders. Hollywood has explored their culture time and again on the silver screen. Larger than life commanders like Julius Caesar would help shape their ultimate destiny. In his book entitled The Rise and Fall of the Roman Empire: Life, Liberty, and the Death of the Republic author Barry Linton highlights and explains the significant struggles and contributions that have made Rome so well known. Join us as we explore the meteoric rise, monumental life, inevitable death, and eventual rebirth of Rome.

    Isolated and desolate, they were largely overlooked by early explorers until Charles Darwin arrived there in the 1830s. It was Darwin who recognized that Galapagos' isolation and desolation were advantages: the paucity of species and lack of outside influences made the workings of natural selection crystal clear. Since then, every important advance and controversy in evolutionary thinking has had its reflection on the Galapagos. In every sense-intellectually, institutionally, and culturally-the history of science on these islands is a history of the way evolutionary science was done for the past 150 years. Evolution's Workshop tells the story of Darwin's explorations there; the fabulous Gilded Age expeditions, run from rich men's gigantic yachts, that featured rough-and-ready science during the day and black-tie dinners every night; the struggle for control of research on the Galapagos; the current efforts by "creation scientists" to use the Galapagos to undercut evolutionary teaching; and many other compelling stories.

    What drives the drug trade, and how has it come to be what it is today? A global history of the acquisition of progressively more potent means of altering ordinary waking consciousness, this book is the first to provide the big picture of the discovery, interchange, and exploitation of the planet's psychoactive resources, from tea and kola to opiates and amphetamines.