The discovery initiated Gessen into a club of sorts: the small (but exponentially expanding) group of people in possession of a new and different way of knowing themselves through what is inscribed in the strands of their DNA. As she wrestled with a wrenching personal decision—what to do with such knowledge—Gessen explored the landscape of this brave new world, speaking with others like her and with experts including medical researchers, historians, and religious thinkers. Blood Matters is a much-needed field guide to this unfamiliar and unsettling territory. It explores the way genetic information is shaping the decisions we make, not only about our physical and emotional health but about whom we marry, the children we bear, even the personality traits we long to have. And it helps us come to terms with the radical transformation that genetic information is engineering in our most basic sense of who we are and what we might become.

    Spelling and grammar errors go unseen after numerous reading. But then, as Bones might say, Jim, I'm a doctor, not an editor.

    If America could send a man to the moon, shouldn’t the best surgeons in the world be able to build an artificial heart? In Ticker, Texas Monthly executive editor and two time National Magazine Award winner Mimi Swartz shows just how complex and difficult it can be to replicate one of nature’s greatest creations. Part investigative journalism, part medical mystery, Ticker is a dazzling story of modern innovation, recounting fifty years of false starts, abysmal failures and miraculous triumphs, as experienced by one the world’s foremost heart surgeons, O.H. “Bud” Frazier, who has given his life to saving the un-savable. His journey takes him from a small town in west Texas to one of the country’s most prestigious medical institutions, The Texas Heart Institute, from the halls of Congress to the animal laboratories where calves are fitted with new heart designs. The roadblocks to success —medical setbacks, technological shortcomings, government regulations – are immense. Still, Bud and his associates persist, finding inspiration in the unlikeliest of places. A field beside the Nile irrigated by an Archimedes screw. A hardware store in Brisbane, Australia. A seedy bar on the wrong side of Houston. Until post WWII, heart surgery did not exist. Ticker provides a riveting history of the pioneers who gave their all to the courageous process of cutting into the only organ humans cannot live without. Heart surgeons Michael DeBakey and Denton Cooley, whose feud dominated the dramatic beginnings of heart surgery. Christian Barnaard, who changed the world overnight by performing the first heart transplant. Inventor Robert Jarvik, whose artificial heart made patient Barney Clark a worldwide symbol of both the brilliant promise of technology and the devastating evils of experimentation run amuck. Rich in supporting players, Ticker introduces us to Bud’s brilliant colleagues in his quixotic quest to develop an artificial heart: Billy Cohn, the heart surgeon and inventor who devotes his spare time to the pursuit of magic and music; Daniel Timms, the Brisbane biomedical engineer whose design of a lightweight, pulseless heart with but a single moving part offers a new way forward. And, as government money dries up, the unlikeliest of backers, Houston’s furniture king, Mattress Mack. In a sweeping narrative of one man’s obsession, Swartz raises some of the hardest questions of the human condition. What are the tradeoffs of medical progress? What is the cost, in suffering and resources, of offering patients a few more months, or years of life? Must science do harm to do good? Ticker takes us on an unforgettable journey into the power and mystery of the human heart.

    We’ll look at what identical twins can teach us about the epigenetic effects of our environment and experiences, why certain genes are 'switched on' or off at various stages of embryonic development, and how scientists have reversed the specialization of cells to clone frogs from a single gut cell. In Introducing Epigenetics, Cath Ennis and Oliver Pugh pull apart the double helix, examining how the epigenetic building blocks and messengers that interpret and edit our genes help to make us, well, us.

    Together these twenty-one articles on a wide range of today's most leading topics in science, from Dennis Overbye, Jonathan Weiner, and Richard Preston, among others, represent the full spectrum of scientific inquiry, proving once again that "good science writing is evidently plentiful" (American Scientist).

    While you could probably learn a lot about each piece, you would have no idea about what the entire picture looks like. This is reductionism -- the idea that to understand the world we only need to study its pieces -- and it is how most social scientists approach their work. In A Crude Look at the Whole, social scientist and economist John H. Miller shows why we need to start looking at whole pictures. For one thing, whether we are talking about stock markets, computer networks, or biological organisms, individual parts only make sense when we remember that they are part of larger wholes. And perhaps more importantly, those wholes can take on behaviors that are strikingly different from that of their pieces. Miller, a leading expert in the computational study of complex adaptive systems, reveals astounding global patterns linking the organization of otherwise radically different structures: It might seem crude, but a beehive's temperature control system can help predict market fluctuations and a mammal's heartbeat can help us understand the "heartbeat" of a city and adapt urban planning accordingly. From enduring racial segregation to sudden stock market disasters, once we start drawing links between complex systems, we can start solving what otherwise might be totally intractable problems. Thanks to this revolutionary perspective, we can finally transcend the limits of reductionism and discover crucial new ideas. Scientifically founded and beautifully written, A Crude Look at the Whole is a powerful exploration of the challenges that we face as a society. As it reveals, taking the crude look might be the only way to truly see.

    Cave paintings of the giant beasts hint at the profound role they played in early human culture-our Ice Age ancestors built igloo-shaped huts out of mammoth bones and even feasted on mammoth tongues. Eager to uncover more clues to this mystical prehistoric age, explorers since the time of Peter the Great have scoured Siberia for mammoth remains. Now a new generation of explorers has taken to the tundra. Armed with GPS, ground-penetrating radar, and Soviet-era military helicopters, they seek an elusive prize: a mammoth carcass that will help determine how the creature lived, how it died-and how it might be brought back to life.In this adventure-filled narrative, science writer Richard Stone follows two teams of explorers-one Russian/Japanese, the other a French-led consortium-as they battle bitter cold, high winds, supply shortages, and the deeply rooted superstitions of indigenous peoples who fear the consequences of awakening the "rat beneath the ice." Stone travels from St. Petersburg to the Arctic Circle, from the North Sea to high-tech Japanese laboratories, as he traces the sometimes-surreal quest of these intrepid scientists, whose work could well rewrite our planet's evolutionary history. A riveting tale of high-stakes adventure and scientific hubris, Mammoth is also an intellectual voyage through uncharted moral terrain, as we confront the promise and peril of resurrecting creatures from the deep past.

    B&W photos throughout. Full-color insert.

    Meridian exercise is a technique developed and perfected over the course of thousands of years in the Asian healing arts traditions.

    Allen and Cowling start with the simple "prokaryotic" cell--cells with no nucleus--and show how the bodies of more complex plants and animals consist of billions of "eukaryotic" cells, of varying kinds, adapted to fill different roles--red blood cells, muscle cells, branched neurons. The authors also show that each cell is an astonishingly complex chemical factory, the activities of which we have only begun to unravel in the past fifty years.

    Indeed, starting from this tiny, common speck, Jan Zalasiewicz offers readers a stimulating tour that begins with the Universe's dramatic birth in the unimaginable violence of the Big Bang and explores the construction of the Solar System and the origins of our own planet. Zalasiewicz shows the almost incredible complexity present in the apparently mundane pebble, starting with the astonishing number of atoms in each. We learn that many events in the Earth's ancient past can be deciphered from a pebble: volcanic eruptions; the lives and deaths of extinct animals and plants; the alien nature of long-vanished oceans; and even the creations of fool's gold and oil deep underground. Zalasiewicz also demonstrates how geologists reach deep into the Earth's past by forensic analysis of even the tiniest amounts of mineral matter. The pebble may be small, and ordinary, but it is also an eloquent part of our Earth's extraordinary, never-ending story.

    How to approach complex normal and abnormal behaviors through biology. How to integrate disciplines including sociobiology, ethology, neuroscience, and endocrinology to examine behaviors such as aggression, sexual behavior, language use, and mental illness.36 hours lectures

    Alex Comfort has revised More Joy of Sex to provide sensible and informed advice on enjoying safe, healthful sex. But the basic mood and intention of More Joy of Sex remains as positive and refreshing as ever. Written with the same humor and balanced perspective that distinguishes its companion volume, The Joy of Sex, More Joy of Sex contains a wealth of challenging and original insights on sexuality and lovemaking. With 32 pages of exquisite, full-color paintings and 70 black-and-white line drawings, More Joy of Sex offers all couples new alternatives and opportunities to explore, enhance, and experience the greatest pleasure from making love.

    Written for both the casual reader and the science buff hungry for new information, The Vision Revolution is a resource that dispels commonly believed perceptions about sight and offers answers drawn from the field’s most recent research.Changizi focuses on four “why” questions:1. Why do we see in color?2. Why do our eyes face forward?3. Why do we see illusions?4. Why does reading come so naturally to us?Why Do We See in Color?It was commonly believed that color vision evolved to help our primitive ancestors identify ripe fruit. Changizi says we should look closer to home: ourselves. Human color vision evolved to give us greater insights into the mental states and health of other people. People who can see color changes in skin have an advantage over their color-blind counterparts; they can see when people are blushing with embarrassment, purple-faced with exertion or the reddening of rashes. Changizi’s research reveals that the cones in our eyes that allow us to see color are exquisitely designed exactly for seeing color changes in the skin. And it’s no coincidence that the primates with color vision are the ones with bare spots on their faces and other body parts; Changizi shows that the development of color vision in higher primates closely parallels the loss of facial hair, culminating in the near hairlessness and highly developed color vision of humans.Why Do Our Eyes Face Forward?Forward-facing eyes set us apart from most mammals, and there is much dispute as to why we have them. While some speculate that we evolved this feature to give us depth perception available through stereo vision, this type of vision only allows us to see short distances, and we already have other mechanisms that help us to estimate distance. Changizi’s research shows that with two forward-facing eyes, primates and humans have an x-ray ability. Specifically, we’re able to see through the cluttered leaves of the forest environment in which we evolved. This feature helps primates see their targets in a crowded, encroached environment. To see how this works, hold a finger in front of your eyes. You’ll find that you’re able to look “through” it, at what is beyond your finger. One of the most amazing feats of two forward-facing eyes? Our views aren’t blocked by our noses, beaks, etc.Why Do We See Illusions?We evolved to see moving objects, not where they are, but where they are going to be. Without this ability, we couldn’t catch a ball because the brain’s ability to process visual information isn’t fast enough to allow us to put our hands in the right place to intersect for a rapidly approaching baseball. “If our brains simply created a perception of the way the world was at the time light hit the eye, then by the time that perception was elicited—which takes about a tenth of a second for the brain to do—time would have marched on, and the perception would be of the recent past,” Changizi explains. Simply put, illusions occur when our brain is tricked into thinking that a stationary two-dimensional picture has an element that is moving. Our brains project the “moving” element into the future and, as a result, we don’t see what’s on the page, but what our brain thinks will be the case a fraction of a second into the future.Why Does Reading Come So Naturally to Us?We can read faster than we can hear, which is odd, considering that reading is relatively recent, and we’ve evolved to process speech for millions of years. Changizi’s research reveals that language has been carefully designed to tap in to elements of the visual processing center that have evolved for tens of millions of years. Visual signs of all languages are shaped like objects in nature, Changizi says, because we have evolved to see nature easily. “People have noticed letters in nature for some time, and there are artists who have a spent a lot of time photographing Latin letters in natural scenes or on butterfly wings,” Changizi says. “For example, if you look at an upper corner of the room you are in, you will see three contours meeting at a point, making a shape close to that of a ‘Y.’“ The Vision Revolution expands upon how our ancestors found the shapes of Latin letters and delves into how visual signs can have similar shapes even though their inspirations come from very different environments.In addition to these four areas, The Vision Revolution explores other phenomena such as cyclopses, peeking and many more you hadn’t even thought to wonder about. Changizi shows how deeply involved these evolutionary aspects of our vision are in why we see the way we do—and what the future holds for us.“…to understand how culture interacts with vision, one must understand not just the eye’s design, but the actual mechanisms we have evolved,” Changizi says, “for culture can tap in to both the designed responses of our brains and the unintended responses.”The Vision Revolution is a book that finally gives attention to what before has been largely neglected by other works on human vision—a book that looks at the “why.”

    The first and only true textbook written by professors who teach the undergraduate course, it presents the most current concepts in an experimental context with clinical advances highlighted in boxes, supported by the kind of helpful pedagogical tools that other books do not provide.