The subject of thermodynamics deals with energy and has long been an essential part of engineering curricula all over the world. Its broad application area ranges from microscopic organisms to common household appliances, transportation vehicles, power generation systems, and even philosophy. This introductory book contains sufficient material for two sequential courses in thermodynamics, and students are assumed to have an adequate background in calculus and physics. A conscious effort is made to emphasize the basic principles of thermodynamics while also providing students with a perspective of how computational tools are used in engineering practice. The traditional classical, or macroscopic, approach is used throughout the text, with microscopic arguments serving in a supporting role as appropriate. This approach is more in line with students’ intuition and makes learning the subject matter much easier.

    Fundamentals of Biostatistics with CD-Rom.

    The Eighth Edition has been thoroughly revised and updated and is available in both print and e-book formats.Janeway s Immunobiology continues to set the standard for currency and authority with its clear writing style and organization, uniform art program, and scientific accuracy. It presents a consistent point of view throughout that of the host s interaction with an environment containing many species of potentially harmful microorganisms. The full-color art program is conceptually coherent and illustrates the processes and mechanisms underlying the concepts in the text. The 16 chapters in this readable, accessible textbook are organized and presented in such a way as to help deliver a complete one-semester immunology course, beginning with innate immunity, then moving to adaptive immunity, and ending with applied clinical immunology.Discussion questions are provided at the end of Chapters 2 to 16. These questions can be used for review, or as the basis for discussion in class or in informal study groups. Summaries conclude each section and each chapter. As in previous editions, a caduceus icon in the margins indicates topics which are correlated to Case Studies in Immunology, Sixth Edition by Geha and Notarangelo.New in the Eighth EditionInnate immunity has been updated and expanded and is now presented in two separate chapters (Chapters 2 and 3), as well as being further emphasized in the rest of the textbook. Chapter 2 covers antimicrobial peptides and the complement system, and Chapter 3 deals with cellular innate receptors and cell-mediated innate immunity (e.g. TLRs, phagocytosis, NK cells, interferon production, innate-like lymphocytes). The section on complement has been reworked and reconceived explaining the lectin pathway first making it easier to teach by placing it into the context of innate recognition. Evolution is now incorporated throughout the text, helping students see similar strategies used by different organisms. The text and figures of Chapter 7 Signaling Through Immune System Receptors have been revised to present a cohesive synthesis of signaling for immunology, focusing on improved illustration of antigen recognition signaling and lymphocyte activation. Signaling through other receptors is dealt with wherever appropriate throughout the book. Updated chapter on B-cell immune responses (Chapter 10), especially on trafficking of B cells in peripheral lymphoid organs (e.g. lymph nodes) and the locations at which they encounter antigen. Coverage of mucosal immunity (Chapter 12) has been brought up to date, including responses to the commensal microbiota and the role of specialized dendritic cells and the regulatory T cells in maintaining tolerance to food antigens and commensal bacteria. Chapter 13, Failures of Host Defense Mechanisms, has been reorganized and revised to structure an understanding of primary immunodeficiencies in the context of developmental pathways. Chapter 16, Manipulation of the Immune Response, has been heavily revised to include a greater emphasis on clinical issues and a complete update of immunotherapeutics and vaccines. Many new and revised figures illustrate the processes and mechanisms underlying the concepts presented in the text. The icons used have been updated and expanded to incorporate a new emphasis on signaling pathways. New references have been added throughout the text.

    Now that machine learning is thriving, even programmers who know close to nothing about this technology can use simple, efficient tools to implement programs capable of learning from data. This practical book shows you how.By using concrete examples, minimal theory, and two production-ready Python frameworks—Scikit-Learn and TensorFlow—author Aurélien Géron helps you gain an intuitive understanding of the concepts and tools for building intelligent systems. You’ll learn how to use a range of techniques, starting with simple Linear Regression and progressing to Deep Neural Networks. If you have some programming experience and you’re ready to code a machine learning project, this guide is for you.This hands-on book shows you how to use:Scikit-Learn, an accessible framework that implements many algorithms efficiently and serves as a great machine learning entry pointTensorFlow, a more complex library for distributed numerical computation, ideal for training and running very large neural networksPractical code examples that you can apply without learning excessive machine learning theory or algorithm details

    By 1949, Godel had produced a remarkable proof: In any universe described by the Theory of Relativity, time cannot exist. Einstein endorsed this result reluctantly but he could find no way to refute it, since then, neither has anyone else. Yet cosmologists and philosophers alike have proceeded as if this discovery was never made. In A World Without Time, Palle Yourgrau sets out to restore Godel to his rightful place in history, telling the story of two magnificent minds put on the shelf by the scientific fashions of their day, and attempts to rescue the brilliant work they did together.

    The algorithms you'll use most often as a programmer have already been discovered, tested, and proven. If you want to take a hard pass on Knuth's brilliant but impenetrable theories and the dense multi-page proofs you'll find in most textbooks, this is the book for you. This fully-illustrated and engaging guide makes it easy for you to learn how to use algorithms effectively in your own programs.Grokking Algorithms is a disarming take on a core computer science topic. In it, you'll learn how to apply common algorithms to the practical problems you face in day-to-day life as a programmer. You'll start with problems like sorting and searching. As you build up your skills in thinking algorithmically, you'll tackle more complex concerns such as data compression or artificial intelligence. Whether you're writing business software, video games, mobile apps, or system utilities, you'll learn algorithmic techniques for solving problems that you thought were out of your grasp. For example, you'll be able to:Write a spell checker using graph algorithmsUnderstand how data compression works using Huffman codingIdentify problems that take too long to solve with naive algorithms, and attack them with algorithms that give you an approximate answer insteadEach carefully-presented example includes helpful diagrams and fully-annotated code samples in Python. By the end of this book, you will know some of the most widely applicable algorithms as well as how and when to use them.

    Over 100 problems at ends of chapters. Answers in back of book. 1962 edition.

    The first part deals with basic ideas, reviewing special relativity and electromagnetism while introducing the concept of extra dimensions. D-branes and the classical dynamics of relativistic strings are discussed next, and the quantization of open and closed bosonic strings in the light-cone gauge, along with a brief introduction to superstrings. The second part begins with a detailed study of D-branes followed by string thermodynamics. It discusses possible physical applications, and covers T-duality of open and closed strings, electromagnetic fields on D-branes, Born/Infeld electrodynamics, covariant string quantization and string interactions. Primarily aimed as a textbook for advanced undergraduate and beginning graduate courses, it will also be ideal for a wide range of scientists and mathematicians who are curious about string theory.

    Astronomy: A Beginner's Guide to the Universe.

    This long-awaited revision contains changes throughout the text. There are new implementations of most of the major programming systems in the book, including the interpreters and compilers, and the authors have incorporated many small changes that reflect their experience teaching the course at MIT since the first edition was published. A new theme has been introduced that emphasizes the central role played by different approaches to dealing with time in computational models: objects with state, concurrent programming, functional programming and lazy evaluation, and nondeterministic programming. There are new example sections on higher-order procedures in graphics and on applications of stream processing in numerical programming, and many new exercises. In addition, all the programs have been reworked to run in any Scheme implementation that adheres to the IEEE standard.

    You'll also learn how to make your programs interactive and how to test your code safely before adding it to a project. In the second half of the book, you'll put your new knowledge into practice with three substantial projects: a Space Invaders-inspired arcade game, data visualizations with Python's super-handy libraries, and a simple web app you can deploy online.As you work through Python Crash Course, you'll learn how to: Use powerful Python libraries and tools, including matplotlib, NumPy, and PygalMake 2D games that respond to keypresses and mouse clicks, and that grow more difficult as the game progressesWork with data to generate interactive visualizationsCreate and customize simple web apps and deploy them safely onlineDeal with mistakes and errors so you can solve your own programming problemsIf you've been thinking seriously about digging into programming, Python Crash Course will get you up to speed and have you writing real programs fast. Why wait any longer? Start your engines and code!

    Although molecular topics are presented first, instructors can assign the chapters in any sequence. Pedagogical features such as chapter-opening “Key Questions” and strategically placed “Keynotes” help readers to efficiently master genetic concepts. The Genetics Place Companion Website contains interactive iActivities and narrated animations that help readers visualize and understand processes and concepts that are illustrated in the book. Genetics: An Introduction, DNA: The Genetic Material, DNA Replication, Gene Control of Proteins, Gene Expression: Transcription,Gene Expression: Translation, DNA Mutation, DNA Repair, and Transposable Elements, Structural Genomics, Functional and Comparative Genomics, Recombinant DNA Technology, Mendelian Genetics, Chromosomal Basis of Inheritance, Extensions of and Deviations from Mendelian Genetic Principles, Genetic Mapping in Eukaryotes, Genetics of Bacteria and Bacteriophages, Variations in Chromosome Structure and Number, Regulation of Gene Expression in Bacteria and Bacteriophages, Regulation of Gene Expression in Eukaryotes, Genetic Analysis of Development, Genetics of Cancer, Quantitative Genetics, Population Genetics, Molecular Evolution Intended for those interested in learning the basics of genetics

    This book will offer students a broad outline of essential mathematics and will help to fill in the gaps in their knowledge. The author explains the basic points and a few key results of all the most important undergraduate topics in mathematics, emphasizing the intuitions behind the subject. The topics include linear algebra, vector calculus, differential and analytical geometry, real analysis, point-set topology, probability, complex analysis, set theory, algorithms, and more. An annotated bibliography offers a guide to further reading and to more rigorous foundations.

    Although it presents the main ideas of quantum theory essentially in nonmathematical terms, it follows these with a broad range of specific applications that are worked out in considerable mathematical detail. Addressed primarily to advanced undergraduate students, the text begins with a study of the physical formulation of the quantum theory, from its origin and early development through an analysis of wave vs. particle properties of matter. In Part II, Professor Bohm addresses the mathematical formulation of the quantum theory, examining wave functions, operators, Schrödinger's equation, fluctuations, correlations, and eigenfunctions.Part III takes up applications to simple systems and further extensions of quantum theory formulation, including matrix formulation and spin and angular momentum. Parts IV and V explore the methods of approximate solution of Schrödinger's equation and the theory of scattering. In Part VI, the process of measurement is examined along with the relationship between quantum and classical concepts.Throughout the text, Professor Bohm places strong emphasis on showing how the quantum theory can be developed in a natural way, starting from the previously existing classical theory and going step by step through the experimental facts and theoretical lines of reasoning which led to replacement of the classical theory by the quantum theory.

    Previously undocumented, these 23 patterns allow designers to create more flexible, elegant, and ultimately reusable designs without having to rediscover the design solutions themselves.The authors begin by describing what patterns are and how they can help you design object-oriented software. They then go on to systematically name, explain, evaluate, and catalog recurring designs in object-oriented systems. With Design Patterns as your guide, you will learn how these important patterns fit into the software development process, and how you can leverage them to solve your own design problems most efficiently. Each pattern describes the circumstances in which it is applicable, when it can be applied in view of other design constraints, and the consequences and trade-offs of using the pattern within a larger design. All patterns are compiled from real systems and are based on real-world examples. Each pattern also includes code that demonstrates how it may be implemented in object-oriented programming languages like C++ or Smalltalk.