As his young daughter starts to investigate the world around her, he too finds himself exploring a new landscape - the shifting and bewildering territory of the brain.Determined to master his new environment, Christian takes us on a fascinating and illuminating journey: through the history of neurology, the joys and anxieties of parenthood, and the ultimate realisation of what, after everything you take for granted has been stripped away from you, is truly important in life.

    Translated into eight languages, it is an essential textbook, an accessible reference, and a bestselling text worldwide.This authoritative textbook retains the successful layout and approach of the bestselling fourth edition Four extra chapters have been added on dry eye, scleritis, corneal and refractive surgery, and systemic diseases.Each chapter have been updated and expanded and the number of illustrations greatly increased.Over a third of the illustrations are new for this editionFour extra chapters have been added on dry eye, scleritis, corneal and refractive surgery, and systemic diseases.The contents of each chapter have been updated and expanded and the number of illustrations has significantly increased.

    Armed with a healthy dose of wit and curiosity, medical journalist Randi Hutter Epstein reveals the “invigorating history” (Nature) of hormones and the age-old quest to control them through the back rooms, basements, and labs where endocrinology began.

    Indeed, most are only barely aware of the diseases caused by them, except, perhaps, for mad cow disease. Yet prions are the stuff of a revolutionary science?a science that might lead to cures for some of humankind?s most devastating diseases.Fatal Flaws is a scientific detective story about this elusive protein, starting with the discovery of kuru, a disease unique to New Guinea in the 1950s that baffled scientists and carried with it whispers of cannibalism. Kuru began a scientific stampede to seek out the agent of this mysterious disease?the prion?a misfolded protein whose existence some of the world?s top scientists still find difficult to accept. Today, the subject of prions remains controversial, yet the proteins might promise new treatments for some of the most intractable brain diseases, ones that affect millions around the planet, including Parkinson?s, ALS and Alzheimer?s.In Fatal Flaws, Jay Ingram unties a complicated interweaving of biology, medicine, human tragedy, surprise and disbelief in the world of prions, and he unravels some of history?s most stunning revelations about disease, the brain and infection.

    Like most people, you probably wake up, get hungry for meals and doze off in bed around the same time every day. If you’ve ever experienced jet lag or pulled an all-nighter, you know that this schedule can easily be thrown off kilter. But for some people, that imbalance—difficulty sleeping at night, hunger at odd times, or sudden fatigue at noon—is a constant. If you're one of those people, Dr. Satchin Panda, one of the leading researchers on circadian rhythms, has a plan to reset your body clock.Beginning with an in-depth explanation of the circadian clock—why it’s important, how it works, and how to know it isn’t working—The Circadian Code outlines lifestyle changes to make to get back on track. It's a concrete plan to enhance weight loss, improve sleep, optimize exercise, and manage technology so that it doesn’t interfere with your body’s natural rhythm. Dr. Panda’s life-changing methods show you how to prevent and reverse ailments like diabetes, cancer, and dementia, as well as microbiome conditions like acid reflux, heartburn, and irritable bowel disease.

    From his intimate knowledge of S., the mnemonist, gained from conversations and testing over a period of almost thirty years, A. R. Luria is able to reveal in rich detail not only the obvious strengths of S.’s astonishing memory but also his surprising weaknesses: his crippling inability to forget, his pattern of reacting passively to life, and his uniquely handicapped personality.

    A man who sees cartoon characters running across the room; a girl whose world turns all Alice in Wonderland; another who transforms into a ragdoll whenever she even thinks about moving.The brain is the most complex structure in the universe. Neurologists must puzzle out life-changing diagnoses from the tiniest of clues. It’s the ultimate medical detective work. In this riveting book, one of the UK’s leading neurologists will take you with her as she follows the clues of her patients’ symptoms. It’s a journey that will open your eyes to the unfathomable intricacies of our brains, and the infinite variety of human capacity and experience.

    Despite its relatively narrow focus, it is chock full of the pearls of clinical wisdom that students and practitioners treasure, and many of these lessons apply to medicine in general. The book was well characterized by a reviewer of an earlier edition for The New England Journal of Medicine: If only one book about surgery could be made available to physicians from all specialties, it should probably be Silen's recent revision of Cope's Early Diagnosis of the Acute Abdomen. Since the book first appeared more than 30 years ago, it has remained the classic treatise on the initial approach to abdominal pain. Because acute, severe abdominal pain is still a common problem whose misdiagnosis can result in quick death, each generation of beginning physicians is faced with the urgency of learning to make a diagnosis in this high anxiety situation and they appreciate the wise, humane, precisely detailed guidance offered by Cope and Silen. For the 21st Edition, Dr. Silen has again updated the text in a respectful but significant way. He has strengthened its emphasis on pitfalls in the interpretation of CT and ultrasound scans, on misadventures caused by over-reliance on blood tests and radiographs, and on careful history-taking to avoid the costs of inappropriate lab tests. He has also reviewed the data from a randomized clinical trial indicating that patients should receive adequate analgesia while awaiting a definitive diagnosis, a dictum that is contrary to traditional teaching