What at first seemed like a case of food poisoning quickly turned critical, and by the time Tom had been transferred via emergency medevac to the world-class medical center at UC San Diego, where both he and Steffanie worked, blood work revealed why modern medicine was failing: Tom was fighting one of the most dangerous, antibiotic-resistant bacteria in the world.Frantic, Steffanie combed through research old and new and came across phage therapy: the idea that the right virus, aka "the perfect predator," can kill even the most lethal bacteria. Phage treatment had fallen out of favor almost 100 years ago, after antibiotic use went mainstream. Now, with time running out, Steffanie appealed to phage researchers all over the world for help. She found allies at the FDA, researchers from Texas A&M, and a clandestine Navy biomedical center -- and together they resurrected a forgotten cure.

    Biden Jr.’s lifelong quest for the presidency by New Yorker political reporter and National Book Award winner Evan Osnos.Former vice president Joseph R. Biden Jr. has been called both the luckiest man and the unluckiest—fortunate to have sustained a fifty-year political career that reached the White House, but also marked by deep personal losses and disappointments that he has suffered. Yet even as Biden’s life has been shaped by drama, it has also been powered by a willingness, rare at the top ranks of politics, to confront his shortcomings, errors, and reversals of fortune. As he says, “Failure at some point in your life is inevitable, but giving up is unforgivable.” His trials have forged in him a deep empathy for others in hardship—an essential quality as he addresses Americans in the nation’s most dire hour in decades. In this concise and trenchant examination, Evan Osnos, winner of the National Book Award, draws on his writings for The New Yorker to capture Biden’s lifelong quest for the American presidency. It is based on lengthy interviews with Biden and on revealing conversations with more than a hundred others, including President Barack Obama, Cory Booker, Amy Klobuchar, Pete Buttigieg, and a range of progressive activists, advisers, opponents, and Biden family members. This portrayal illuminates Biden’s long and eventful career in the Senate, his eight years as Obama’s vice president, his sojourn in the political wilderness after being passed over for Hillary Clinton in 2016, his decision to challenge Donald Trump for the presidency, and his choice of Senator Kamala Harris as his running mate. Osnos ponders the difficulties Biden will face if elected and weighs how political circumstances, and changes in the candidate’s thinking, have altered his positions. In this nuanced portrait, Biden emerges as flawed, yet resolute, and tempered by the flame of tragedy—a man who just may be uncannily suited for his moment in history.

    It's a story that is one part danger, one part action, and all true. It's a story about how and why we fight for our democracy and win."Celebrated national leader and bestselling author Stacey Abrams offers a blueprint to end voter suppression, empower our citizens, and take back our country. A recognized expert on fair voting and civic engagement, Abrams chronicles a chilling account of how the right to vote and the principle of democracy have been and continue to be under attack. Abrams would have been the first African American woman governor, but experienced these effects firsthand, despite running the most innovative race in modern politics as the Democratic nominee in Georgia. Abrams didn’t win, but she has not conceded. The book compellingly argues for the importance of robust voter protections, an elevation of identity politics, engagement in the census, and a return to moral international leadership.Our Time Is Now draws on extensive research from national organizations and renowned scholars, as well as anecdotes from her life and others’ who have fought throughout our country’s history for the power to be heard. The stakes could not be higher. Here are concrete solutions and inspiration to stand up for who we are―now.

    A right wing survivalist amasses a cache of weapons and resists calls to surrender. A drug trafficker barricades himself and his family in a railroad car, and begins shooting. A cult leader in Waco, Texas faces the FBI in an armed stand-off that leaves many dead in a fiery blaze. A sniper, claiming to be God, terrorizes the DC metropolitan area. For most of us, these are events we hear about on the news. For Gary Noesner, head of the FBI’s groundbreaking Crisis Negotiation Unit, it was just another day on the job. In Stalling for Time, Noesner takes readers on a heart-pounding tour through many of the most famous hostage crises of the past thirty years. Specially trained in non-violent confrontation and communication techniques, Noesner’s unit successfully defused many potentially volatile standoffs, but perhaps their most hard-won victory was earning the recognition and respect of their law enforcement peers.Noesner pursued his dream of joining the FBI all the way to Quantico, where he not only became a Special Agent, but also—in the course of a distinguished thirty-year career—the FBI’s Chief Negotiator. Gaining respect for the fledgling art of crisis negotiation in the hard-boiled culture of The Bureau, where the shadow of J. Edgar Hoover still loomed large, was an uphill battle, educating FBI and law enforcement leaders on the job at an incident, and advocating the use of psychology rather than force whenever possible. Noesner’s many bloodless victories rarely garnered as much media attention as the notorious incident management blunders like the Branch Davidian disaster in Waco and the Ruby Ridge tragedy.Noesner offers a candid as well as fascinating look back at his years as a rebel in the ranks and a pioneer on the front lines. Whether vividly recounting showdowns with the radical Republic of Texas militia, the terrorist hijackers of the cruise ship Achille Lauro, and self-styled messiah David Koresh, or clashes with colleagues and superiors that expose the internal politics and power-plays of America’s premier law enforcement agency, Stalling for Time crackles with breathtaking suspense and insight in equal measure. Case by case, minute by minute, it’s a behind the scenes view of a visionary crime-fighter in action.

    Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with - and perished from - for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. From the Persian Queen Atossa, whose Greek slave cut off her malignant breast, to the nineteenth-century recipients of primitive radiation and chemotherapy to Mukherjee’s own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through fiercely demanding regimens in order to survive—and to increase our understanding of this iconic disease. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

    The daughter of immigrants, she was raised in an Oakland, California community that cared deeply about social justice; her parents--an esteemed economist from Jamaica and an admired cancer researcher from India--met as activists in the civil rights movement when they were graduate students at Berkeley. Growing up, Harris herself never hid her passion for justice, and when she became a prosecutor out of law school, a deputy district attorney, she quickly established herself as one of the most innovative change agents in American law enforcement. She progressed rapidly to become the elected District Attorney for San Francisco, and then the chief law enforcement officer of the state of California as a whole. Known for bringing a voice to the voiceless, she took on the big banks during the foreclosure crisis, winning a historic settlement for California's working families. Her hallmarks were applying a holistic, data-driven approach to many of California's thorniest issues, always eschewing stale "tough on crime" rhetoric as presenting a series of false choices. Neither "tough" nor "soft" but smart on crime became her mantra. Being smart means learning the truths that can make us better as a community, and supporting those truths with all our might. That has been the pole star that guided Harris to a transformational career as the top law enforcement official in California, and it is guiding her now as a transformational United States Senator, grappling with an array of complex issues that affect her state, our country, and the world, from health care and the new economy to immigration, national security, the opioid crisis, and accelerating inequality.By reckoning with the big challenges we face together, drawing on the hard-won wisdom and insight from her own career and the work of those who have most inspired her, Kamala Harris offers in The Truths We Hold a master class in problem-solving, in crisis management, and leadership in challenging times. Through the arc of her own life, on into the great work of our day, she communicates a vision of shared struggle, shared purpose, and shared values. In a book rich in many home truths, not least is that a relatively small number of people work very hard to convince a great many of us that we have less in common than we actually do, but it falls to us to look past them and get on with the good work of living our common truth. When we do, our shared effort will continue to sustain us and this great nation, now and in the years to come.

    Bush to victory. That was ironic, because Winchester, like countless American small towns, is fast becoming the bedrock of a permanent underclass. Two in five of the people in his old neighborhood do not have high school diplomas. Nearly everyone over fifty has serious health problems, and many have no health care. Credit ratings are low or nonexistent, and alcohol, overeating, and Jesus are the preferred avenues of escape.A raucous mix of storytelling and political commentary, Deer Hunting with Jesus is Bageant's report on what he learned by coming home. He writes of his childhood friends who work at factory jobs that are constantly on the verge of being outsourced; the mortgage and credit card rackets that saddle the working poor with debt, i.e., white trashonomics; the ubiquitous gun culture”and why the left doesn't get it; Scots Irish culture and how it played out in the young life of Lynddie England; and the blinkered magical thinking of the Christian right. (Bageant's brother is a Baptist pastor who casts out demons.) What it adds up to, he asserts, is an unacknowledged class war. By turns brutal, tender, incendiary, and seriously funny, this book is a call to arms for fellow progressives with little real understanding of the great beery, NASCAR-loving, church-going, gun-owning America that has never set foot in a Starbucks.Deer Hunting with Jesus is a potent antidote to what Bageant dubs the "American hologram" the televised, corporatized virtual reality that distracts us from the insidious realities of American life.

    The enemy sits across the table and sleeps in the next room. Her husband of twenty-one years is plotting against her because he feels increasingly threatened - by Elizabeth's intellect, independence, and unwillingness to stifle her own thoughts. So Theophilus makes a plan to put his wife back in her place. One summer morning, he has her committed to an insane asylum.The horrific conditions inside the Illinois State Hospital in Jacksonville, Illinois, are overseen by Dr. Andrew McFarland, a man who will prove to be even more dangerous to Elizabeth than her traitorous husband. But most disturbing is that Elizabeth is not the only sane woman confined to the institution. There are many rational women on her ward who tell the same story: they've been committed not because they need medical treatment, but to keep them in line - conveniently labeled "crazy" so their voices are ignored.No one is willing to fight for their freedom and, disenfranchised both by gender and the stigma of their supposed madness, they cannot possibly fight for themselves. But Elizabeth is about to discover that the merit of losing everything is that you then have nothing to lose...

    We see how they rebrand themselves as saviors of the poor; how they lavishly reward "thought leaders" who redefine "change" in winner-friendly ways; and how they constantly seek to do more good, but never less harm. We hear the limousine confessions of a celebrated foundation boss; witness an American president hem and haw about his plutocratic benefactors; and attend a cruise-ship conference where entrepreneurs celebrate their own self-interested magnanimity.Giridharadas asks hard questions: Why, for example, should our gravest problems be solved by the unelected upper crust instead of the public institutions it erodes by lobbying and dodging taxes? He also points toward an answer: Rather than rely on scraps from the winners, we must take on the grueling democratic work of building more robust, egalitarian institutions and truly changing the world. A call to action for elites and everyday citizens alike.

    In the span of twelve hours, lives can be lost, life-altering medical treatment decisions made, and dreams fulfilled or irrevocably stolen. In Brown’s skilled hands--as both a dedicated nurse and an insightful chronicler of events--we are given an unprecedented view into the individual struggles as well as the larger truths about medicine in this country, and by shift’s end, we have witnessed something profound about hope and healing and humanity. Every day, Theresa Brown holds patients' lives in her hands. On this day there are four. There is Mr. Hampton, a patient with lymphoma to whom Brown is charged with administering a powerful drug that could cure him--or kill him; Sheila, who may have been dangerously misdiagnosed; Candace, a returning patient who arrives (perhaps advisedly) with her own disinfectant wipes, cleansing rituals, and demands; and Dorothy, who after six weeks in the hospital may finally go home. Prioritizing and ministering to their needs takes the kind of skill, sensitivity, and, yes, humor that enable a nurse to be a patient’s most ardent advocate in a medical system marked by heartbreaking dysfunction as well as miraculous success.

    Jacobs tackles his most challenging experiment yet: a yearlong mission to radically improve every element of his body and mind—from his brain to his fingertips to his abs.From the bestselling author of The Year of Living Biblically and The Know-It-All comes the true and truly hilarious story of one person’s quest to become the healthiest man in the world. Hospitalized with a freak case of tropical pneumonia, goaded by his wife telling him, “I don’t want to be a widow at forty-five,” and ashamed of a middle-aged body best described as “a python that swallowed a goat,” A.J. Jacobs felt compelled to change his ways and get healthy. And he didn’t want only to lose weight, or finish a triathlon, or lower his cholesterol. His ambitions were far greater: maximal health from head to toe. The task was epic. He consulted an army of experts— sleep consultants and sex clinicians, nutritionists and dermatologists. He subjected himself to dozens of different workouts—from Strollercize classes to Finger Fitness sessions, from bouldering with cavemen to a treadmill desk. And he took in a cartload of diets: raw foods, veganism, high protein, calorie restriction, extreme chewing, and dozens more. He bought gadgets and helmets, earphones and juicers. He poked and he pinched. He counted and he measured. The story of his transformation is not only brilliantly entertaining, but it just may be the healthiest book ever written. It will make you laugh until your sides split and endorphins flood your bloodstream. It will alter the contours of your brain, imprinting you with better habits of hygiene and diet. It will move you emotionally and get you moving physically in surprising ways. And it will give you occasion to reflect on the body’s many mysteries and the ultimate pursuit of health: a well-lived life.

    The media seized hold of the story and, in the process, helped to launch one of the most devastating health scares ever. In the years to come Wakefield would be revealed as a profiteer in league with class-action lawyers, and he would eventually lose his medical license. Meanwhile, one study after another failed to find any link between childhood vaccines and autism. Yet the myth that vaccines somehow cause developmental disorders lives on. Despite the lack of corroborating evidence, it has been popularized by media personalities such as Oprah Winfrey and Jenny McCarthy and legitimized by journalists who claim that they are just being fair to “both sides” of an issue about which there is little debate. Meanwhile, millions of dollars have been diverted from potential breakthroughs in autism research; families have spent their savings on ineffective “miracle cures"; and declining vaccination rates have led to outbreaks of deadly illnesses like Hib, measles, and whooping cough. Most tragic of all is the increasing number of children dying from vaccine-preventable diseases. In The Panic Virus Seth Mnookin draws on interviews with parents, public-health advocates, scientists, and anti-vaccine activists to tackle a fundamental question: How do we decide what the truth is? The fascinating answer helps explain everything from the persistence of conspiracy theories about 9/11 to the appeal of talk-show hosts who demand that President Obama “prove” he was born in America. The Panic Virus is the ultimate cautionary tale for our time.

    Evicted transforms our understanding of poverty and economic exploitation while providing fresh ideas for solving one of 21st-century America's most devastating problems. Its unforgettable scenes of hope and loss remind us of the centrality of home, without which nothing else is possible.

    But in her speech she was in a mood to consider her life, her legacy, her departure from the country she was now triumphantly returning to. “I was a devil in other countries, and I was a little devil in America, too,” she told the crowd. Inspired by these few words, Hanif Abdurraqib has written a profound and lasting reflection on how Black performance is inextricably woven into the fabric of American culture. Each moment in every performance he examines—whether it’s the twenty-seven seconds in “Gimme Shelter” in which Merry Clayton wails the words “rape, murder,” a schoolyard fistfight, a dance marathon, or the instant in a game of spades right after the cards are dealt—has layers of resonance in Black and white cultures, the politics of American empire, and Abdurraqib’s own personal history of love, grief, and performance.Abdurraqib writes prose brimming with jubilation and pain, infused with the lyricism and rhythm of the musicians he loves. With care and generosity, he explains the poignancy of performances big and small, each one feeling intensely familiar and vital, both timeless and desperately urgent. Filled with sharp insight, humor, and heart, A Little Devil in America exalts the Black performance that unfolds in specific moments in time and space—from midcentury Paris to the moon, and back down again to a cramped living room in Columbus, Ohio.

    Now he broadens the warning: the entire human game, he suggests, has begun to play itself out.Bill McKibben’s groundbreaking book The End of Nature -- issued in dozens of languages and long regarded as a classic -- was the first book to alert us to global warming. But the danger is broader than that: even as climate change shrinks the space where our civilization can exist, new technologies like artificial intelligence and robotics threaten to bleach away the variety of human experience.Falter tells the story of these converging trends and of the ideological fervor that keeps us from bringing them under control. And then, drawing on McKibben’s experience in building 350.org, the first truly global citizens movement to combat climate change, it offers some possible ways out of the trap. We’re at a bleak moment in human history -- and we’ll either confront that bleakness or watch the civilization our forebears built slip away.Falter is a powerful and sobering call to arms, to save not only our planet but also our humanity.