Arthur Allen reveals a history of vaccination that is both illuminated with hope and shrouded by controversy - covering Jenner's discovery to Pasteur's vaccines for rabies and cholera, to those that safeguarded the children of the 20th century.

    Eyes wide open. I was standing at an open window, staring at the dizzying curve of Riverside Drive, five floors below. I’d stopped, somehow, poised, about to jump.Growing up the good girl in an Irish American family full of drinkers and terrible sleepers, Kathleen Frazier was twelve when her seemingly innocent sleepwalking turned dangerous. Over the next few years, she was a popular A+ student by day, the star of her high school musical. At night, she both longed for and dreaded sleep.Frazier moved to Manhattan in the 1980s, hoping for a life in the theater but getting a run of sleepwalking performances instead. Efforts to abate her malady with drinking failed miserably. She became promiscuous, looking for nighttime companionship. Could a bed partner save her from flinging herself down a flight of stairs or out an open window? Exhaustion stalked her, and rest and love were seemingly out of reach.This is the journey Frazier illuminates in her intimate memoir. While highlighting her quest to beat her sleep terrors and insomnia, this is ultimately a story of health, hope, and redemption.

    This fascinating collection of historical curiosities explores some of the strangest cases that have perplexed doctors across the world.From seventeenth-century Holland to Tsarist Russia, from rural Canada to a whaler in the Pacific, many are monuments to human stupidity – such as the sailor who swallowed dozens of penknives to amuse his shipmates, or the chemistry student who in 1850 arrived at a hospital in New York with his penis trapped inside a bottle, having unwisely decided to relieve himself into a vessel containing highly reactive potassium. Others demonstrate exceptional surgical ingenuity long before the advent of anaesthesia – such as a daring nineteenth-century operation to remove a metal fragment from beneath a conscious patient’s heart. We also hear of the weird, often hilarious remedies employed by physicians of yore – from crow’s vomit to port-wine enemas – the hazards of such everyday objects as cucumbers and false teeth, and miraculous recovery from apparently terminal injuries.

    Experts in the media, medical science, and government alike are scrambling to find answers. What or who is responsiblefor this fat crisis, and what can we do to stop it?Abigail Saguy argues that these fraught and frantic debates obscure a more important question: How has fatness come to be understood as a public health crisis at all? Why, she asks, has the view of fat as a problem-a symptom of immorality, a medical pathology, a public health epidemic-come todominate more positive framings of weight-as consistent with health, beauty, or a legitimate rights claim-in public discourse? Why are heavy individuals singled out for blame? And what are the consequences of understanding weight in these ways?What's Wrong with Fat? presents each of the various ways in which fat is understood in America today, examining the implications of understanding fatness as a health risk, disease, and epidemic, and revealing why we've come to understand the issue in these terms, despite considerable scientificuncertainty and debate. Saguy shows how debates over the relationship between body size and health risk take place within a larger, though often invisible, contest over whether we should understand fatness as obesity at all. Moreover, she reveals that public discussions of the obesity crisis domore harm than good, leading to bullying, weight-based discrimination, and misdiagnoses.Showing that the medical framing of fat is literally making us sick, What's Wrong with Fat? provides a crucial corrective to our society's misplaced obsession with weight.

    But it took a team of Oxford scientists headed by Howard Florey and Ernst Chain four more years to develop it as the first antibiotic, and the most important family of drugs in the twentieth century. At once the world was transformed—major bacterial scourges such as blood poisoning and pneumonia, scarlet fever and diphtheria, gonorrhea and syphilis were defeated as penicillin helped to foster not only a medical revolution but a sexual one as well. In his wonderfully engaging book, acclaimed author Eric Lax tells the real story behind the discovery and why it took so long to develop the drug. He reveals the reasons why credit for penicillin was misplaced, and why this astonishing achievement garnered a Nobel Prize but no financial rewards for Alexander Fleming, Florey, and his team. The Mold in Dr. Florey’s Coat is the compelling story of the passage of medicine from one era to the next and of the eccentric individuals whose participation in this extraordinary accomplishment has, until now, remained largely unknown.

    A physician-anthropologist with more than fifteen years in the field, Farmer writes from the front lines of the war against these modern plagues and shows why, even more than those of history, they target the poor. This "peculiarly modern inequality" that permeates AIDS, TB, malaria, and typhoid in the modern world, and that feeds emerging (or re-emerging) infectious diseases such as Ebola and cholera, is laid bare in Farmer's harrowing stories of sickness and suffering.Challenging the accepted methodologies of epidemiology and international health, he points out that most current explanatory strategies, from "cost-effectiveness" to patient "noncompliance," inevitably lead to blaming the victims. In reality, larger forces, global as well as local, determine why some people are sick and others are shielded from risk. Yet this moving account is far from a hopeless inventory of insoluble problems. Farmer writes of what can be done in the face of seemingly overwhelming odds, by physicians determined to treat those in need. Infections and Inequalities weds meticulous scholarship with a passion for solutions—remedies for the plagues of the poor and the social maladies that have sustained them.

    When first published in 1969, this study was described by the Guardian as …as exciting and readable an account as you could wish." This new edition of the major study on the subject is illustrated by over seventy contemporary black and white illustrations and eight pages of color.A series of natural disasters in the furthest reaches of the Orient during the third of the fourteenth century heralded what was, for the population of Europe, the most devastating period of death and destruction in its history. By the autumn of 1347 the Black Death had reached the shores of the eastern Mediterranean, and the years that followed were to witness a horrifying and apparently relentless epidemic.One third of England's population died between the years 1347 and 1350, and over one thousand villages were deserted, never to be repopulated. In towns and cities the cemeteries were unable to provide space for all the dead, and violence and crime spiraled. Travel became dangerous and interruption of food and other supplies across the country added hunger and deprivation to the problems of people already overwhelmed by the threat of the vilest of deaths. In the countryside the population was halved in places, and as land became plentiful, landowners' profits fell and the government tried in vain to fix labourers' wages and prices, peasant unrest accelerated and the manorial system disintegrated, culminating eventually in the Peasants' Revolt of 1381. Throughout Europe whole societies were disrupted; racial tensions built as a direct result of the plague, and persecution of Jews began in earnest throughout the continent. The social and economic consequences of the period were to reach far into the following century.

    People are waking up to the seedy history of the world's art collections, and are starting to ask difficult questions about what the future of museums should look like. In The Whole Picture, art historian and Uncomfortable Art Tour guide Alice Procter provides a manual for deconstructing everything you thought you knew about art, and fills in the blanks with the stories that have been left out of the art history canon for centuries. The book is divided into four chronological sections, named after four different kinds of art space:The Palace The Classroom The Memorial The Playground Each section tackles the fascinating and often shocking stories of five different art pieces, including the propaganda painting that the East India Company used to justify its control in India; the Maori mokomokai skulls that were traded and collected by Europeans as 'art objects'; and Kara Walker's controversial contemporary sculpture A Subtlety, which raised questions about 'appropriate' interactions with art. Through these stories, Alice brings out the underlying colonial narrative lurking beneath the art industry today, and suggests different ways of seeing and thinking about art in the modern world.The Whole Picture is a much-needed provocation to look more critically at the accepted narratives about art, and rethink and disrupt the way we interact with the museums and galleries that display it.

    Intriguingly fascinating and entertaining reading for anyone who is interested in how society copes with catastrophe and pain. Relevant today in face of the worldwide medical calamity of AIDS. Continuously in print since its first publication in 1934, with over 75 printings.

    The birth gurus of ancient times told newlyweds that simultaneous orgasms were necessary for conception and that during pregnancy a woman should drink red wine but not too much and have sex but not too frequently. Over the last one hundred years, depending on the latest prevailing advice, women have taken morphine, practiced Lamaze, relied on ultrasound images, sampled fertility drugs, and shopped at sperm banks.In Get Me Out, the insatiably curious Randi Hutter Epstein journeys through history, fads, and fables, and to the fringe of science, where audacious researchers have gone to extreme measures to get healthy babies out of mothers. Here is an entertaining must-read—and an enlightening celebration of human life.

    The DOs chronicles the development of this controversial medical movement from the nineteenth century to the present. Historian Norman Gevitz describes the philosophy and practice of osteopathy, as well as its impact on medical care. From the theories underlying the use of spinal manipulation developed by osteopathy's founder, Andrew Taylor Still, Gevitz traces the movement's early success, despite attacks from the orthodox medical community, and details the internal struggles to broaden osteopathy's scope to include the full range of pharmaceuticals and surgery. He also recounts the efforts of osteopathic colleges to achieve parity with institutions granting M.D. degrees and looks at the continuing effort by osteopathic physicians and surgeons to achieve greater recognition and visibility.In print continuously since 1982, The DOs has now been thoroughly updated and expanded to include two new chapters addressing recent and current challenges and to bring the history of the profession up to the beginning of the new millennium.

    The Sackler name adorns the walls of many storied institutions: Harvard, the Metropolitan Museum of Art, Oxford, the Louvre. They are one of the richest families in the world, known for their lavish donations to the arts and sciences. The source of the family fortune was vague, however, until it emerged that the Sacklers were responsible for making and marketing OxyContin, a blockbuster painkiller that was a catalyst for the opioid crisis.Empire of Pain is a masterpiece of narrative reporting and writing, exhaustively documented and ferociously compelling.

    Cross-country truckers and suburban mothers. Trailer parks, gay sex clubs, college campuses, and military battlefields. In this fascinating book, Frank Owen traces the spread of methamphetamine—meth—from its origins as a cold and asthma remedy to the stimulant wiring every corner of American culture.            Meth is the latest “epidemic” to attract the attention of law enforcement and the media, but like cocaine and heroin its roots are medicinal. It was first synthesized in the late nineteenth century and applied in treatment of a wide range of ailments; by the 1940s meth had become a wonder drug, used to treat depression, hyperactivity, obesity, epilepsy, and addictions to other drugs and alcohol. Allied, Nazi, and Japanese soldiers used it throughout World War II, and the returning waves of veterans drove demand for meth into the burgeoning postwar suburbs, where it became the “mother’s helper” for a bored and lonely generation.            But meth truly exploded in the 1960s and ’70s, when biker gang cooks using burners, beakers, and plastic tubes brought their expertise from California to the Ozarks, the Southwest, and other remote rural areas where the drug could be manufactured in kitchen labs. Since then, meth has been the target of billions of dollars in federal, state, and local anti-drug wars. Murders, violent assaults, thefts, fires, premature births, and AIDS—rises in all of these have been blamed on the drug that crosses classes and subcultures like no other.            Acclaimed journalist Frank Owen follows the users, cooks, dealers, and law enforcers to uncover a dramatic story being played out in cities, small towns, and farm communities across America. No Speed Limit is a panoramic, high-octane investigation by a journalist who knows firsthand the powerful highs and frightening lows of meth.

    A work of extraordinary imaginative invention, it might be described as “novelistic fantasy”—a pioneering new direction in fiction which created its own protean form as it was written. Patchen mingled narrative with dream visions, surrealism with satire, poetry with statements of principle, and explored the then almost uncharted territory of visual word structures twenty years before “Concrete Poetry” became a popular international movement.Sleepers Awake is a rallying cry to young and old, as Patchen advances his long struggle against inhumanity, oppression, war and hypocrisy. Now brutal, now lyrical, he gives us life and the world as we must take these if they are to have full meaning; the horror and the beauty, the joy and the suffering together.

    As the mother of forensic science, Frances Glessner Lee is the reason why homicide detectives are a thing. She is responsible for the popularity of forensic science in television shows and pop culture. Long overlooked in the history books, this extremely detailed and thoroughly researched biography will at long last tell the story of the life and contributions of this pioneering woman.