Prusiner received a Nobel Prize, the world's most prestigious award for achievement in physiology or medicine. That he was the sole recipient of the award for the year was entirely appropriate, for his struggle to identify the agent responsible for ravaging the brains of animals suffering from scrapie and mad cow disease, and of humans with Creutzfeldt-Jakob disease, had been waged largely alone and in some cases in the face of strenuous disagreement.   In this book, Prusiner tells the remarkable story of his discovery of prions—infectious proteins that replicate and cause disease but surprisingly contain no genetic material—and reveals how superb and meticulous science is actually practiced using talented teams of researchers who persevere. He recounts the frustrations and rewards of years of research and offers fascinating portraits of his peers as they raced to discover the causes of fatal brain diseases. Prusiner’s hypothesis, once considered heresy, now stands as accepted science and the basis for developing diagnoses and eventual cures. He closes with a meditation on the legacy of his discovery: What will it take to cure Alzheimer’s, Parkinson’s, Lou Gehrig’s and other devastating diseases of the brain?

    Our beginners guide contains all the essential information you need in order to succeed. It covers the basic techniques, well illustrated with over a hundred images, and explains everything you need to know in an understandable way. Bonsai Empire is the world's most visited Bonsai website and has provided beginners with quality information for over a decade. We have developed this guide to help you get a taste of this fascinating and living art, and hope you'll enjoy it as much as we do! This book includes: - Over 100 stunning images - Over 80 pages - Explanations of the basic techniques - Care guides on the 10 most popular tree species - Background on the history, definition and styles Walter Pall: "Now here is the ultimate book to lead beginners. I am happy to have been able to contribute to this" Mauro Stemberger "Very clear" and "With great quality drawings and pics"

    This is not the full 200+ page book. This concise summary of Gawande’s manifesto will convey everything you need to know about how and why checklists are so effective and how to successfully compose your own checklists. These checklists will improve your level of success in any field or activity you are trying to achieve excellence in. Put yourself head and shoulders above the competition with this simple, intuitive tool. Not convinced that a checklist is sophisticated enough for your particular goal? Gawande presents case studies showing the effectiveness of the checklist in a range of complex environments from surgery to aviation, engineering to emergency response, venture capitalism to disease control. Imagine if you could substantially eradicate your own human fallibility with such a simple tool! By engaging with the simple concepts in this short guide you will be able to devise and implement the checklists that will ensure your peak performance in every area of your life.

    For the student and the professional.

    Hailed as the most outstanding book in the biomedical sciences when it was originally published in 1990, Manic-Depressive Illness was the first to survey this massive body of evidence comprehensively and to assess its meaning for both clinician and scientist. It also vividly portrayed the experience of manic-depressive illness from the perspective of patients, their doctors, and researchers. Encompassing an understanding about the illness as Kraeplin conceived of it- about its cyclical course and about the essential unity of its bipolar and recurrent unipolar forms- the book has become the definitive work on the topic, revered by both specialists and nonspecialists alike. Now, in this magnificent second edition, Drs. Frederick Goodwin and Kay Redfield Jamison bring their unique contribution to mental health science into the 21st century. In collaboration with a team of other leading scientists, a collaboration designed to preserve the unified voice of the two authors, they exhaustively review the biological and genetic literature that has dominated the field in recent years and incorporate cutting-edge research conducted since publication of the first edition. They also update their surveys of psychological and epidemiological evidence, as well as that pertaining to diagnostic issues, course, and outcome, and they offer practical guidelines for differential diagnosis and clinical management. The medical treatment of manic and depressive episodes is described, strategies for preventing future episodes are given in detail, and psychotherapeutic issues common in this illness are considered. Special emphasis is given to fostering compliance with medication regimens and treating patients who abuse drugs and alcohol or who pose a risk of suicide. This book, unique in the way that it retains the distinct perspective of its authors while assuring the maximum in-depth coverage of a vastly expanded base of scientific knowledge, will be a valuable and necessary addition to the libraries of psychiatrists and other physicians, psychologists, clinical social workers, neuroscientists, pharmacologists, and the patients and families who live with manic-depressive illness.

    This is a combination of what is speculation, along with some thoughts on life, business, society, and language. An excellent thought starter. Also contains Watts classic -Thoughts on Life- - short aphorisms of timeless wisdom. The orignal source for classic market wisdom such as: -Make your theories fit your facts, not your facts your theories.- -Look after the principal; the interest will look after itself.- -If a speculation keeps you awake at night, sell down to the sleeping point- This book is a must for any reader of classic investing wisdom.

    Fear and Trembling and The Sickness Unto Death established Kierkegaard as the father of existentialism and have come to define his contribution to philosophy. Lowrie's translation, first published in 1941 and later revised, was the first in English, and it has introduced hundreds of thousands of readers to Kierkegaard's thought. Kierkegaard counted Fear and Trembling and The Sickness Unto Death among "the most perfect books I have written," and in them he introduces two terms--"the absurd" and "despair"--that have become key terms in modern thought. Fear and Trembling takes up the story of Abraham and Isaac to explore a faith that transcends the ethical, persists in the face of the absurd, and meets its reward in the return of all that the faithful one is willing to sacrifice, while The Sickness Unto Death examines the spiritual anxiety of despair.

    A dynamic table of contents enables to jump directly to the chapter selected. Table of Contents - About This Book - The Duty Of Inquiry - The Weight Of Authority - The Limits Of Inference

    Hawkins M.D., Ph.D., on the nature of consciousness, spirit, and ego are known worldwide by students seeking to realize spiritual Truth.        As a mystic, Dr. Hawkins has infused the truths found in the precepts of Western religion with the core of Eastern philosophy, bridging the familiar, physical world to the nonlinear, spiritual domain.        This collection of passages, carefully selected from Dr. Hawkins’s extensive writings, offers readers a new contemplation for each day. Any one of these passages, fully understood, can elevate one’s level of consciousness.

    What is needed is the courage to face the way things are, and the wisdom and imagination to work out how to make things better.'Australia's unprecedented run of economic growth has failed to deliver a more stable or harmonious society. Individualism is rampant. Income inequality is growing. Public education is under-resourced. The gender revolution is stalling. We no longer trust our major institutions or our political leaders. We are more socially fragmented, more anxious, more depressed, more overweight, more medicated, deeper in debt and increasingly addicted - whether to our digital devices, drugs, pornography or 'stuff'.Yet esteemed social researcher Hugh Mackay remains optimistic. Twenty-five years ago, he revolutionised Australian social analysis with the publication of Reinventing Australia. Now he takes another unflinching look at us and offers some compelling proposals for a more compassionate and socially cohesive Australia. You might not agree with everything he suggests, but you'll find it hard to get some of his ideas out of your head.Argued with intelligence and passion, this book is essential reading for everyone who loves Australia enough to want to make it a better place for us all.

    A lady code. It’s ancient, it’s deeply spiritual and more than that, it’s powerful. Fiercely powerful. So powerful that it’s barely been spoken about in over 2,000 years. Your menstrual cycle. Yep, your period is way more than PMS, carb cravings and lady rage, your menstrual cycle/period/ragtime/ – insert whatever you call your ’time of the month’ here – is actually a 4-part lady code, that once cracked, will uncover a series of monthly superpowers that can be used to enhance your relationships with others, build a better business, have incredible sex + create a ‘bloody’ amazing life. Code Red, from the creatrix of www.thesassyshe.com, Lisa Lister, is a call to action. A rallying cry that dares you to explore, navigate and most importantly, love your lady landscape. You'll learn how to live and work in complete alignment with the rhythms of nature, the moon and your menstrual cycle, be inspired by insights from Wise + Wild Women like Meggan Watterson, Alexandra Pope + Uma Dinsmore Tuli and gain access to easy-to-follow strategies and SHE Flow yoga practices. You'll be invited to connect with your true nature as a woman, tap into the transformational power of your innate feminine wisdom and use your menstrual cycle as an ever-unfolding map to crack your lady code. REVIEWS “Lisa Lister is the woman we all wish we were lucky enough to have as our sister. But short of having her on speed dial, this book is the next best thing to a full on feminine support system!” - Kathleen McGowan, Activist and International Bestselling Author of The Expected One & The Book of Love “Code Red is a modern priestess guide for women to go within and use their feminine cycles to lead the good life. Lisa Lister is sounding the call for you to heal your cycle, accept your ever changing body, and honor your feminine soul. This is the essential foundation and practice for you to get in your ‘FLO’ and become the powerful force of nature that you are designed to be!” - Alisa Vitti, Hormonal Health Expert and Author of WomanCode “Lisa Lister doesn’t mess around. She’s here to break boundaries and barriers that have been created by what society defines ‘normal’ and in turn, remind us what’s real. Teaching and leading other girls to honour their divinity inside and out is no easy task and for that reason alone, I respect Lisa wholeheartedly. As far as I’m concerned, Lisa is part angel, part goddess and part rocker – she writes in a way that’s friendly, honest and captivating. This book is filled with ‘aha!’ moments from beginning to end. Let Code Red help you recognize your monthly flow – as a reminder you are fiercely feminine.” - Kyle Gray, Bestselling Author of Angel Prayers “Lisa’s sheer passion is palpable, whether she’s presenting her practical guide to getting the most out of your cycle or tackling complex philosophical questions of femaleness. She stands strong in that space between cycle-worship and cycle-commodification, making room for more women to feel self-knowledge through body acceptance is here for them, too. To paraphrase Gail Dines, if women loved their bodies, how much might society change for the better? Lisa gives us a glimpse of a bright future.” - Holly Grigg-Spall, Author of Sweetening the Pill: or How We Got Hooked on the Hormonal Birth Control "I've been searching for this book for years. Lisa Lister sheds the veil on the hidden power of the divine feminine with sass, compassion and deep wisdom. Jam packed full of tools, stories and even tips for guys...

    Instead of struggling even harder to manage or eliminate your anger, you can stop anger feelings from determining who you are and how you live your life. Based on a revolutionary psychological approach called acceptance and commitment therapy (ACT), the techniques in ACT on Life Not on Anger can help you let go of anger and start living your life to the fullest.Your path begins as you learn to accept your angry feelings as they occur, without judging or trying to manage them. Then, using techniques based in mindfulness practice, you'll discover how to observe your feelings of anger without acting on them. Value-identification exercises help you figure out what truly matters to you so that you can commit to short- and long-term goals that turn your values into reality. In the process, anger will lose power over your life-and, amazingly, you'll gain control over your life by simply letting go of your angry feelings.

    Born in Los Angeles, she is taken to Mexico to live with her extended family until the age of three. Olivia then returns to L.A. to live with her mother, Carmen, the live-in maid to a wealthy family. Mother and daughter sleep in the maid’s room, just off the kitchen. Olivia is raised alongside the other children of the family. She goes to school with them, eats meals with them, and is taken shopping for clothes with them. She is like a member of the family. Except she is not. Based on over twenty years of research, Mary Romero brings Olivia’s remarkable story to life. We watch as she grows up among the children of privilege, struggles through adolescence, declares her independence and eventually goes off to college and becomes a successful professional. Much of this extraordinary story is told in Olivia’s voice and we hear of both her triumphs and setbacks. We come to understand the painful realization of wanting to claim a Mexican heritage that is in many ways not her own and of her constant struggle to come to terms with the great contradictions in her life.

    Regular price: $4.99.***+FREE GIFT INSIDE: link to download my 120 page e-book “Mindfulness Based Stress and Anxiety Management Tools” for free! Dear Friends, Contrary to popular belief, Zen is not a discipline reserved for monks practicing Kung Fu. Although there is some truth to this idea, Zen is a practice that is applicable, useful, and pragmatic for anyone to study regardless of what religion you follow (or don’t follow). Zen is the practice of studying your subconscious and seeing your true nature. The purpose of this work is to show you how to apply and utilize the teachings and essence of Zen in everyday life in the Western society. I’m not really an “absolute truth seeker” unworldly type of person - I just believe in practical plans and blueprints that actually help in living a better life. Of course I will tell you about the origin of Zen and the traditional ways of practicing it, but I will also show you my side of things, my personal point of view and translation of many Zen truths through a more “contemporary” and practical language. It is a “modern Zen lifestyle” type of book. I invite you to take this journey into the peaceful world of Zen Buddhism with me today! In This Book You Will Read About: • Where Did Zen Come From? - A short history and explanation of Zen • What Does Zen Teach? - The major teachings and precepts of Zen • Various Zen meditation techniques that are applicable and practical for everyone! • The benefits of a Zen lifestyle • What Zen Buddhism is NOT? • How to slow down and start enjoying your life • How to accept everything and lose nothing • Why being alone can be beneficial • Why pleasure is NOT happiness • Six Ways to Practically Let Go • How to de-clutter your life and live simply • "Mindfulness on Steroids" • How to Take Care of your Awareness and Focus • Where to start and how to practice Zen as a regular person • And many other interesting concepts... Scroll to the top of the page and click the orange buy button to instantly download this book to your PC, Kindle, Mac or smartphone!

    Like the dogs he loves, Masson's writing--drawn from myth and literature, scientific studies and true accounts--will capture readers with its playful, mysterious, and serious sides.