Patient H.M.: A Story of Memory, Madness, and Family Secrets


Luke Dittrich - 2016
    These “psychosurgeons,” as they called themselves, occupied a gray zone between medical research and medical practice, and ended up subjecting untold numbers of people to the types of surgical experiments once limited to chimpanzees.The most important test subject to emerge from this largely untold chapter in American history was a twenty-seven-year-old factory worker named Henry Molaison. In 1953, Henry—who suffered from severe epilepsy—received a radical new version of the lobotomy, one that targeted the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry left the operating room profoundly amnesic, unable to create new long-term memories. Over the next sixty years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.Luke Dittrich uses the case of Patient H.M. as a starting point for a kaleidoscopic journey, one that moves from the first recorded brain surgeries in ancient Egypt to the cutting-edge laboratories of MIT. He takes readers inside the old asylums and operating theaters where psychosurgeons conducted their human experiments, and behind the scenes of a bitter custody battle over the ownership of the most important brain in the world. Throughout, Dittrich delves into the enduring mysteries of the mind while exposing troubling stories of just how far we’ve gone in our pursuit of knowledge. It is also, at times, a deeply personal journey. Dittrich’s grandfather was the brilliant, morally complex surgeon who operated on Molaison—and thousands of other patients. The author’s investigation into the dark roots of modern memory science ultimately forces him to confront unsettling secrets in his own family history, and to reveal the tragedy that fueled his grandfather’s relentless experimentation—experimentation that would revolutionize our understanding of ourselves.Patient H.M. combines the best of biography, memoir, and science journalism to create a haunting, endlessly fascinating story, one that reveals the wondrous and devastating things that can happen when hubris, ambition, and human imperfection collide.

A Liberated Mind: How to Pivot Toward What Matters


Steven C. Hayes - 2019
    Hayes describes it with more depth and clarity than ever before.-Mark Manson, #1 New York Times best-selling author of The Subtle Art of Not Giving a F*ck Life is not a problem to be solved. ACT shows how we can live full and meaningful lives by embracing our vulnerability and turning toward what hurts. In this landmark book, the originator and pioneering researcher into Acceptance and Commitment Therapy (ACT) lays out the psychological flexibility skills that make it one of the most powerful approaches research has yet to offer. These skills have been shown to help even where other approaches have failed. Science shows that they are useful in virtually every area--mental health (anxiety, depression, substance abuse, eating disorders, PTSD); physical health (chronic pain, dealing with diabetes, facing cancer); social processes (relationship issues, prejudice, stigma, domestic violence); and performance (sports, business, diet, exercise).How does psychological flexibility help? We struggle because the problem-solving mind tells us to run from what causes us fear and hurt. But we hurt where we care. If we run from a sense of vulnerability, we must also run from what we care about. By learning how to liberate ourselves, we can live with meaning and purpose, along with our pain when there is pain.Although that is a simple idea, it resists our instincts and programming. The flexibility skills counter those ingrained tendencies. They include noticing our thoughts with curiosity, opening to our emotions, attending to what is in the present, learning the art of perspective taking, discovering our deepest values, and building habits based around what we deeply want.Beginning with the epiphany Steven Hayes had during a panic attack, this book is a powerful narrative of scientific discovery filled with moving stories as well as advice for how we can put flexibility skills to work immediately. Hayes shows how allowing ourselves to feel fully and think freely moves us toward commitment to what truly matters to us. Finally, we can live lives that reflect the qualities we choose.

Zoobiquity: The Astonishing Connection Between Human and Animal Health


Barbara Natterson-Horowitz - 2012
    Beginning with the above questions, she began informally researching every affliction that she encountered in humans to learn whether it happened with animals, too. And usually, it did: dinosaurs suffered from brain cancer, koalas can catch chlamydia, reindeer seek narcotic escape in hallucinogenic mushrooms, stallions self-mutilate, and gorillas experience clinical depression. Natterson-Horowitz and science writer Kathryn Bowers have dubbed this pan-species approach to medicine zoobiquity. Here, they present a revelatory understanding of what animals can teach us about the human body and mind, exploring how animal and human commonality can be used to diagnose, treat, and heal patients of all species.

Rewire Your Anxious Brain: How to Use the Neuroscience of Fear to End Anxiety, Panic, and Worry


Catherine M. Pittman - 2015
    The amygdala acts as a primal response, and oftentimes, when this part of the brain processes fear, you may not even understand why you are afraid. By comparison, the cortex is the center of “worry.” That is, obsessing, ruminating, and dwelling on things that may or may not happen. In the book, Pittman and Karle make it simple by offering specific examples of how to manage fear by tapping into both of these pathways in the brain. As you read, you’ll gain a greater understanding how anxiety is created in the brain, and as a result, you will feel empowered and motivated to overcome it. The brain is a powerful tool, and the more you work to change the way you respond to fear, the more resilient you will become. Using the practical self-assessments and proven-effective techniques in this book, you will learn to literally “rewire” the brain processes that lie at the root of your fears.

Louder Than Words: The New Science of How the Mind Makes Meaning


Benjamin K. Bergen - 2012
    You can use it to talk about all sorts of things -- from your new labradoodle puppy to the expansive gardens at Versailles, from Roger Federer's backhand to things that don't exist at all, like flying pigs. And when you talk, your listener fills in lots of details you didn't mention -- the curliness of the dog's fur or the vast statuary on the grounds of the French palace. What's the trick behind this magic? How does meaning work?In Louder than Words, cognitive scientist Benjamin Bergen draws together a decade’s worth of research in psychology, linguistics, and neuroscience to offer a new theory of how our minds make meaning. When we hear words and sentences, Bergen contends, we engage the parts of our brain that we use for perception and action, repurposing these evolutionarily older networks to create simulations in our minds. These embodied simulations, as they're called, are what makes it possible for us to become better baseball players by merely visualizing a well-executed swing; what allows us to remember which cupboard the diapers are in without looking, and what makes it so hard to talk on a cell phone while we're driving on the highway. Meaning is more than just knowing definitions of words, as others have previously argued. In understanding language, our brains engage in a creative process of constructing rich mental worlds in which we see, hear, feel, and act.Through whimsical examples and ingenious experiments, Bergen leads us on a virtual tour of the new science of embodied cognition. A brilliant account of our human capacity to understand language, Louder than Words will profoundly change how you read, speak, and listen.

Cognitive Behavioral Therapy: Techniques for Retraining Your Brain


Jason M. Satterfield - 2015
    CBT illuminates the links between thoughts, emotions, behaviors, and physical health and uses those connections to develop concrete plans for self-improvement. Built on a solid foundation of neurological and behavioral research, CBT is an approach almost anyone can use for promoting greater mental health and improving quality of life. In 24 engaging half-hour lectures, you'll build a robust and effective self-improvement toolkit with the expert guidance of Professor Satterfield of the University of California, San Francisco. You will explore CBT's roots in Socratic and stoic philosophy, build a toolkit of CBT techniques, and hear about the latest research about its outcomes. Additionally this intriguing and practical course allows you to take on the role of medical student, physician, psychologist, and patient. Throughout the course you'll explore issues that cause people to seek out therapy. In some cases you'll get to hear Dr. Satterfield working with a patient, and in others you'll be delving into research to find what causes issues and how CBT helps to resolve them. Everyone has something about their life that they would like to improve. With the tools in CBT and the desire to make your situation better, you can create lasting change in your life.

The Panic Virus: A True Story of Medicine, Science, and Fear


Seth Mnookin - 2011
    The media seized hold of the story and, in the process, helped to launch one of the most devastating health scares ever. In the years to come Wakefield would be revealed as a profiteer in league with class-action lawyers, and he would eventually lose his medical license. Meanwhile, one study after another failed to find any link between childhood vaccines and autism. Yet the myth that vaccines somehow cause developmental disorders lives on. Despite the lack of corroborating evidence, it has been popularized by media personalities such as Oprah Winfrey and Jenny McCarthy and legitimized by journalists who claim that they are just being fair to “both sides” of an issue about which there is little debate. Meanwhile, millions of dollars have been diverted from potential breakthroughs in autism research; families have spent their savings on ineffective “miracle cures"; and declining vaccination rates have led to outbreaks of deadly illnesses like Hib, measles, and whooping cough. Most tragic of all is the increasing number of children dying from vaccine-preventable diseases. In The Panic Virus Seth Mnookin draws on interviews with parents, public-health advocates, scientists, and anti-vaccine activists to tackle a fundamental question: How do we decide what the truth is? The fascinating answer helps explain everything from the persistence of conspiracy theories about 9/11 to the appeal of talk-show hosts who demand that President Obama “prove” he was born in America. The Panic Virus is the ultimate cautionary tale for our time.

Hacking Darwin: Genetic Engineering and the Future of Humanity


Jamie Metzl - 2019
    After 3.8 billion years humankind is about to start evolving by new rules...From leading geopolitical expert and technology futurist Jamie Metzl comes a groundbreaking exploration of the many ways genetic-engineering is shaking the core foundations of our lives -- sex, war, love, and death.At the dawn of the genetics revolution, our DNA is becoming as readable, writable, and hackable as our information technology. But as humanity starts retooling our own genetic code, the choices we make today will be the difference between realizing breathtaking advances in human well-being and descending into a dangerous and potentially deadly genetic arms race.Enter the laboratories where scientists are turning science fiction into reality. Look towards a future where our deepest beliefs, morals, religions, and politics are challenged like never before and the very essence of what it means to be human is at play. When we can engineer our future children, massively extend our lifespans, build life from scratch, and recreate the plant and animal world, should we?

Social: Why Our Brains Are Wired to Connect


Matthew D. Lieberman - 2013
    It is believed that we must commit 10,000 hours to master a skill.  According to Lieberman, each of us has spent 10,000 hours learning to make sense of people and groups by the time we are ten.  Social argues that our need to reach out to and connect with others is a primary driver behind our behavior.  We believe that pain and pleasure alone guide our actions.  Yet, new research using fMRI – including a great deal of original research conducted by Lieberman and his UCLA lab -- shows that our brains react to social pain and pleasure in much the same way as they do to physical pain and pleasure.  Fortunately, the brain has evolved sophisticated mechanisms for securing our place in the social world.  We have a unique ability to read other people’s minds, to figure out their hopes, fears, and motivations, allowing us to effectively coordinate our lives with one another.  And our most private sense of who we are is intimately linked to the important people and groups in our lives.  This wiring often leads us to restrain our selfish impulses for the greater good.  These mechanisms lead to behavior that might seem irrational, but is really just the result of our deep social wiring and necessary for our success as a species.   Based on the latest cutting edge research, the findings in Social have important real-world implications.  Our schools and businesses, for example, attempt to minimalize social distractions.  But this is exactly the wrong thing to do to encourage engagement and learning, and literally shuts down the social brain, leaving powerful neuro-cognitive resources untapped.  The insights revealed in this pioneering book suggest ways to improve learning in schools, make the workplace more productive, and improve our overall well-being.

I Contain Multitudes: The Microbes Within Us and a Grander View of Life


Ed Yong - 2016
    Many people think of microbes as germs to be eradicated, but those that live with us—the microbiome—build our bodies, protect our health, shape our identities, and grant us incredible abilities. In this astonishing book, Ed Yong takes us on a grand tour through our microbial partners, and introduces us to the scientists on the front lines of discovery. Yong, whose humor is as evident as his erudition, prompts us to look at ourselves and our animal companions in a new light—less as individuals and more as the interconnected, interdependent multitudes we assuredly are. The microbes in our bodies are part of our immune systems and protect us from disease. Those in cows and termites digest the plants they eat. In the deep oceans, mysterious creatures without mouths or guts depend on microbes for all their energy. Bacteria provide squids with invisibility cloaks, help beetles to bring down forests, and allow worms to cause diseases that afflict millions of people. I Contain Multitudes is the story of these extraordinary partnerships, between the creatures we are familiar with and those we are not. It reveals how we humans are disrupting these partnerships and how we might manipulate them for our own good. It will change both our view of nature and our sense of where we belong in it.

The Secret Life of the Grown-Up Brain: The Surprising Talents of the Middle-Aged Mind


Barbara Strauch - 2010
    But new research from neuroscientists and psychologists suggests that, in fact, the brain reorganizes, improves in important functions, and even helps us adopt a more optimistic outlook in middle age. Growth of white matter and brain connectors allow us to recognize patterns faster, make better judgments, and find unique solutions to problems. Scientists call these traits cognitive expertise and they reach their highest levels in middle age. In her impeccably researched book, science writer Barbara Strauch explores the latest findings that demonstrate, through the use of technology such as brain scans, that the middle-aged brain is more flexible and more capable than previously thought. For the first time, long-term studies show that our view of middle age has been misleading and incomplete. By detailing exactly the normal, healthy brain functions over time, Strauch also explains how its optimal processes can be maintained. Part scientific survey, part how-to guide, "The Secret Life of the Grown-Up Brain" is a fascinating glimpse at our surprisingly talented middle-aged minds."

Mind to Matter: The Astonishing Science of How Your Brain Creates Material Reality


Dawson Church - 2018
    It’s held as a firm proposition in metaphysics, and some spiritual teachers ascribe infinite powers to the mind. But are these claims scientifically accurate? What does the scientific evidence tell us about the scope of the human mind to transform thoughts into reality?New research and new discoveries in epigenetics, neuroscience, electromagnetism, psychology, cymatics (the study of wave phenomena), public health, and quantum physics are demonstrating that thoughts can indeed be profoundly creative. In Mind to Matter, award-winning author Dawson Church examines the scientific facts and reviews the studies that show, step by step, exactly how our minds create material form. As each piece of the puzzle falls into place, the science turns out to be even more astonishing than the metaphysics.Throughout the book, Church shares illuminating case histories—up-close, authentic personal accounts of people who had an experience of turning mind into matter. Drawn from the worlds of medicine, sports, business, healing, art, and scientific discovery, these stories run the gamut from profound to inspiring to heart-wrenching. Meticulously researched evidence is presented in highly relatable form, using engaging, understandable, nontechnical analogies. Photos and illustrations enrich the text.As we discover how the universe operates synchronistically, we come to understand that while we have individual local minds, we also participate in universal nonlocal mind. Mind to Matter shows us that as we take charge of our individual power to create, we have the potential, as a species, to catalyze a transformation of our whole world.

Being You: A New Science of Consciousness


Anil Seth - 2020
    Somehow, within each of our brains, billions of neurons work to create our conscious experience. How does this happen? Why do we experience life in the first person? After over twenty years researching the brain, world-renowned neuroscientist Anil Seth puts forward a radical new theory of consciousness and self. His unique theory of what it means to 'be you' challenges our understanding of perception and reality and it turns what you thought you knew about yourself on its head.'Awe-inspiring and humane.' NEW STATESMAN (Books of the Year)'Fascinating.' FINANCIAL TIMES (Books of the Year)'Profound.' GUARDIAN (Books of the Year)'Brilliant.' CLAIRE TOMALIN, NEW YORK TIMES'Outstanding.' PSYCHOLOGY TODAY 'Amazing . . . a brilliant read.'RUSSELL BRAND'Beautifully written, crystal clear, deeply insightful.'DAVID EAGLEMAN, Pulitzer Prize-nominated author of Livewired'Offers us new cause for astonishment and wonder.'ANNAKA HARRIS, author of Conscious'A fascinating book. A joy to read.'NIGEL WARBURTON'Truly compelling.'PROFESSOR KARL FRISTON, Universty College London'A wonderfully accessible and comprehensive account.'SEAN CARROLL, author of Something Deeply Hidden

When the Body Says No: The Cost of Hidden Stress


Gabor Maté - 2003
    With great compassion and erudition, Gabor Maté demystifies medical science and, as he did in Scattered Minds, invites us all to be our own health advocates.

Heart: A History


Sandeep Jauhar - 2018
    It’s so bound up with our deepest feelings that emotional trauma causes it to change shape.Practising cardiologist Sandeep Jauhar beautifully weaves his own experiences with the defining discoveries of the past to tell the story of our most vital organ. He looks at some of the pioneers who risked their careers and their patients’ lives to better understand the heart. People like Daniel Hale Williams, who performed the world’s first documented heart surgery, and Wilson Greatbatch, who accidentally invented the pacemaker.Amid gripping scenes from the operating theatre, Jauhar interweaves stories about the patients he’s treated with the moving tale of his family’s own history of heart problems, from his grandfather’s sudden death in India – an event that sparked his life-long obsession – to the ominous signs of how he himself might die.He also confronts the limits of medical technology and argues that future progress will be determined more by how we choose to live rather than by any device we invent.