Arriving in Manhattan in the mid-nineties, Goodwillie quickly falls into one implausible job after another. He becomes a private investigator, imagining himself as a gumshoe, a hired gun—only to realize that he's more adept at bungling cases than at solving them. When, in his stint as a freelance journalist, he unveils the Mafia in a magazine exposé, he succeeds only in becoming a target of their wrath. As a copywriter for a sports auction house, he imagines documenting the great histories hidden in priceless artifacts but finds himself forced to write about a lock of Mickey Mantle's hair. Even when he seems to break through, somehow becoming the sports expert at Sotheby's auction house—appearing on major news networks, raking in a hefty salary—he's lured away by the promise of Internet millions...just in time for the dot-com crash. Teeming with the vibrancy of a city in hyperdrive, Seemed Like a Good Idea at the Time recounts a dizzying and enthralling search for authenticity in a cynical, superficial—and suddenly dangerous—age. In his heartbreaking and hilarious struggle to become a big-city writer, Goodwillie becomes something more: an important voice of the lost generation he so elegantly describes.

    Everyone is doing it now.Disarmed of falsehood, he was left only with the awful truth: John Hodgman is an older white male monster with bad facial hair, wandering like a privileged Sasquatch through three wildernesses: the hills of Western Massachusetts where he spent much of his youth; the painful beaches of Maine that want to kill him (and some day will); and the metaphoric haunted forest of middle age that connects them.Vacationland collects these real life wanderings, and through them you learn of the horror of freshwater clams, the evolutionary purpose of the mustache, and which animals to keep as pets and which to kill with traps and poison. There is also some advice on how to react when the people of coastal Maine try to sacrifice you to their strange god.Though wildly, Hodgmaniacally funny as usual, it is also a poignant and sincere account of one human facing his forties, those years when men in particular must stop pretending to be the children of bright potential they were and settle into the failing bodies of the wiser, weird dads that they are.

    As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his co-discovery of the structure of DNA. She and her collaborators turned ​a curiosity ​of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020.

    The disintegration of this group, a process that has been slowly occurring now for more than forty years, has been reported with growing frequency and alarm, but has never before been written about as searingly from the inside. J. D. Vance tells the true story of what a social, regional, and class decline feels like when you were born with it hung around your neck.The Vance family story begins hopefully in postwar America. J. D.’s grandparents were “dirt poor and in love,” and moved north from Kentucky’s Appalachia region to Ohio in the hopes of escaping the dreadful poverty around them. They raised a middle-class family, and eventually one of their grandchildren would graduate from Yale Law School, a conventional marker of success in achieving generational upward mobility. But as the family saga of Hillbilly Elegy plays out, we learn that J.D.'s grandparents, aunt, uncle, sister, and, most of all, his mother struggled profoundly with the demands of their new middle-class life, never fully escaping the legacy of abuse, alcoholism, poverty, and trauma so characteristic of their part of America. With piercing honesty, Vance shows how he himself still carries around the demons of his chaotic family history.A deeply moving memoir, with its share of humor and vividly colorful figures, Hillbilly Elegy is the story of how upward mobility really feels. And it is an urgent and troubling meditation on the loss of the American dream for a large segment of this country.

    Only a few weeks old, on the coldest night of the year, he was stuffed into the returned book slot at the Spencer Public Library. He was found the next working by library director Vicki Myron, a single mother who had survived the loss of her family farm, a breast cancer scare, and an alcoholic husband. Dewey won her heart, and the hearts of the staff, by pulling himself up and hobbling on frostbitten feet to nudge each of hem in a gesture of thanks and love. For the next nineteen years, he never stopped charming the people of Spencer with this enthusiasm, warmth, humility (for a cat), and, above all, his sixth sense about who needed him most.As his fame grew from town to town, then state to state, and finally, amazingly, worldwide, Dewey became more than just a friend; he became a source of pride for an extraordinary Heartland farming town pulling its way slowly back from the greatest crisis in its long history.

    Like a house. We could just buy a block of land, you know, the four of us, and have a go.' It was just an idea. then it started to take shape. In this frank, funny and thought-provoking memoir, Richard Glover describes how he and his friend Philip and their partners built a house in the bush on weekends. It was a huge and exhausting undertaking ... not least because they decided to use mudbricks. 'Imagine this - with mudbrick you have a building that is made out of the very earth it stands on ... there is another thing: the stuff is free. Once we buy the land we'll have no money left. this way we can get started as soon as we have the block.' In the end it took three years simply to make the bricks. As for the house itself ... But the process gave Richard the opportunity to examine things he had never quite reconciled to himself - big things like what it means to be a man, the nature of male relationships, fatherhood - and to challenge himself in the kind of blokey environment he had rejected. Above all, the mud house proved that even if it 'wasn't the ceiling of the Sistine Chapel' there is nothing like the satisfaction of making something with your own hands.

    I know. No one says it but I know…” —from Signs of Life Twenty-four-year-old Natalie Taylor was leading a charmed life. At the age of twenty four, she had a fulfilling job as a high school English teacher, a wonderful husband, a new house and a baby on the way.  Then, while visiting her sister, she gets the news that Josh has died in a freak accident.  Four months before the birth of her son, Natalie is leveled by loss.   What follows is an incredibly powerful emotional journey, as Natalie calls upon resources she didn’t even know she had in order to re-imagine and re-build a life for her and her son. In vivid and immediate detail, Natalie documents her life from the day of Josh’s death through the birth their son, Kai, as she struggles in her role as a new mother where everyone is watching her for signs of impending collapse.  With honesty, raw pain, and most surprising, a wicked sense of humor, Natalie recounts the agonies and unexpected joys of her new life.  There is the frustration of holidays, navigating the relationship with her in-laws, the comfort she finds and unlikely friendship she forges in support groups and the utterly breathtaking, but often overwhelming new motherhood.   When she returns to the classroom, she finds that little is more healing than the honesty and egocentricity of teenagers.   Drawing on lessons from beloved books like The Color Purple and The Catcher in the Rye and the talk shows she suddenly can’t get enough of, from the strength of her family and friends, and from a rich fantasy life—including a saucy fairy godmother who guides her grieving—Natalie embarks on the ultimate journey of self-discovery and realizes you can sometimes find the best in yourself during the worst life has to offer.  And she delivers these lessons, in way that feels like she’s right beside you in her bathrobe and with a glass of wine--the cool, funny girlfriend you love to stay up all night with.   Unforgettable and utterly absorbing, Signs of Life features a powerful, wholly original debut voice that will have you crying and laughing to the very last page.

    She writes songs about her anatomy, talks trash about her one-eyed rescue pug, and sexually harasses her husband, Stephen. And it pays the bills! Now, in her first-ever book, Laura recounts how she went from being a dangerously impulsive, broke, unemployable, suicidal, cocaine-addicted narcissist, crippled by fear and hopping from one toxic romance to the next…to a more-happy-than-not, somewhat rational, meditating, vegan yogi with good credit, a great marriage, a fantastic career, and four unfortunate-looking rescue animals. Still, above all, Laura remains an amazingly talented, adorable, and vulnerable, self-described…Idiot. With her signature brand of offbeat, no-holds-barred humor, Idiot introduces you to a wildly original—and undeniably relatable—new voice.Oh, the places I've peed --High school Hammer time --My summer of (possibly too much) freedom --How to ignore a hundred red flags --The Damon inside --A spoonful of sugar --Look, Mom! I'm on TV! --New beginnings (but, like, for real) --Two apartments and a home --Maggie: cat --Walking through fear

    By the time he turned sixty, he had lost everything except his Ivy League education and his sense of entitlement. First, he was downsized at work. Next, an affair ended his twenty-year marriage. Then, he was diagnosed with a slow-growing brain tumor, prognosis undetermined. Around the same time, his girlfriend gave birth to a son. Gill had no money, no health insurance, and no prospects. One day as Gill sat in a Manhattan Starbucks with his last affordable luxury—a latté—brooding about his misfortune and quickly dwindling list of options, a 28-year-old Starbucks manager named Crystal Thompson approached him, half joking, to offer him a job. With nothing to lose, he took it, and went from drinking coffee in a Brooks Brothers suit to serving it in a green uniform. For the first time in his life, Gill was a minority--the only older white guy working with a team of young African-Americans. He was forced to acknowledge his ingrained prejudices and admit to himself that, far from being beneath him, his new job was hard. And his younger coworkers, despite having half the education and twice the personal difficulties he’d ever faced, were running circles around him. The other baristas treated Gill with respect and kindness despite his differences, and he began to feel a new emotion: gratitude. Crossing over the Starbucks bar was the beginning of a dramatic transformation that cracked his world wide open. When all of his defenses and the armor of entitlement had been stripped away, a humbler, happier and gentler man remained. One that everyone, especially Michael’s kids, liked a lot better. The backdrop to Gill's story is a nearly universal cultural phenomenon: the Starbucks experience. In How Starbucks Saved My Life, we step behind the counter of one of the world's best-known companies and discover how it all really works, who the baristas are and what they love (and hate) about their jobs. Inside Starbucks, as Crystal and Mike’s friendship grows, we see what wonders can happen when we reach out across race, class, and age divisions to help a fellow human being.

    Powell first arrived at the servants' entrance of one of those great houses in the 1920s. As a kitchen maid - the lowest of the low - she entered an entirely new world; one of stoves to be blacked, vegetables to be scrubbed, mistresses to be appeased, and bootlaces to be ironed. Work started at 5:30am and went on until after dark. It was a far cry from her childhood on the beaches of Hove, where money and food were scarce, but warmth and laughter never were. Yet from the gentleman with a penchant for stroking the housemaids' curlers, to raucous tea-dances with errand boys, to the heartbreaking story of Agnes the pregnant under-parlormaid, fired for being seduced by her mistress's nephew, Margaret's tales of her time in service are told with wit, warmth, and a sharp eye for the prejudices of her situation. Margaret Powell's true story of a life spent in service is a fascinating "downstairs" portrait of the glittering, long-gone worlds behind the closed doors of Downton Abbey and 165 Eaton Place.

    When I almost died it was just after midday.When the Taliban took control of the Swat Valley in Pakistan, one girl spoke out. Malala Yousafzai refused to be silenced and fought for her right to an education.On Tuesday, October 9, 2012, when she was fifteen, she almost paid the ultimate price. She was shot in the head at point-blank range while riding the bus home from school, and few expected her to survive. Instead, Malala's miraculous recovery has taken her on an extraordinary journey from a remote valley in northern Pakistan to the halls of the United Nations in New York. At sixteen, she has become a global symbol of peaceful protest and the youngest-ever Nobel Peace Prize laureate.I Am Malala is the remarkable tale of a family uprooted by global terrorism, of the fight for girls' education, of a father who, himself a school owner, championed and encouraged his daughter to write and attend school, and of brave parents who have a fierce love for their daughter in a society that prizes sons.

    Now I’m letting my guard down.” —Hillary Rodham Clinton, from the introduction of What HappenedFor the first time, Hillary Rodham Clinton reveals what she was thinking and feeling during one of the most controversial and unpredictable presidential elections in history. Now free from the constraints of running, Hillary takes you inside the intense personal experience of becoming the first woman nominated for president by a major party in an election marked by rage, sexism, exhilarating highs and infuriating lows, stranger-than-fiction twists, Russian interference, and an opponent who broke all the rules. This is her most personal memoir yet. In these pages, she describes what it was like to run against Donald Trump, the mistakes she made, how she has coped with a shocking and devastating loss, and how she found the strength to pick herself back up afterward. With humor and candor, she tells readers what it took to get back on her feet—the rituals, relationships, and reading that got her through, and what the experience has taught her about life. She speaks about the challenges of being a strong woman in the public eye, the criticism over her voice, age, and appearance, and the double standard confronting women in politics. She lays out how the 2016 election was marked by an unprecedented assault on our democracy by a foreign adversary. By analyzing the evidence and connecting the dots, Hillary shows just how dangerous the forces are that shaped the outcome, and why Americans need to understand them to protect our values and our democracy in the future. The election of 2016 was unprecedented and historic. What Happened is the story of that campaign and its aftermath—both a deeply intimate account and a cautionary tale for the nation.

    Today, it is the most common form of officially classified mental illness. Scott Stossel gracefully guides us across the terrain of an affliction that is pervasive yet too often misunderstood. Drawing on his own long-standing battle with anxiety, Stossel presents an astonishing history, at once intimate and authoritative, of the efforts to understand the condition from medical, cultural, philosophical, and experiential perspectives. He ranges from the earliest medical reports of Galen and Hippocrates, through later observations by Robert Burton and Søren Kierkegaard, to the investigations by great nineteenth-century scientists, such as Charles Darwin, William James, and Sigmund Freud, as they began to explore its sources and causes, to the latest research by neuroscientists and geneticists. Stossel reports on famous individuals who struggled with anxiety, as well as on the afflicted generations of his own family. His portrait of anxiety reveals not only the emotion’s myriad manifestations and the anguish anxiety produces but also the countless psychotherapies, medications, and other (often outlandish) treatments that have been developed to counteract it. Stossel vividly depicts anxiety’s human toll—its crippling impact, its devastating power to paralyze—while at the same time exploring how those who suffer from it find ways to manage and control it. My Age of Anxiety is learned and empathetic, humorous and inspirational, offering the reader great insight into the biological, cultural, and environmental factors that contribute to the affliction.

    Using mostly short entries organized from A to Z, many of which are cross-referenced, Rosenthal captures in wonderful and episodic detail the moments, observations, and emotions that comprise a contemporary life. Start anywhere—preferably at the beginning—and see how one young woman’s alphabetized existence can open up and define the world in new and unexpected ways.An ordinary life, perhaps, but an extraordinary book.Cross-section of ordinary life at this exact momentA security guard is loosening his belt.A couple is at a sushi restaurant with some old friends. They are reminiscing. In the back of their minds, they are thinking of being home.A woman is trying to suck on a cherry Lifesaver but will end up biting it in six seconds.A little boy is riding the train home with his dad after spending the day together at his office.A man is running back into a grocery store to look for a scarf he dropped. He will leave with the phone number of a woman who will become his wife.Words the author meant to useFlair, Luxurious, Panoply, Churlish, Dainty, FollyWines that go nicely with this bookreds: Marcel Lapierre Morgon (France), Alario Dolcetto d’Alba Costa Fiore (Italy) whites: King Estate Pinot Gris (Oregon), Landmark Chardonnay Overlook (CaliforniaBook, standing in the bookstore holding aIf I am standing there with the book in my hand, one of three things has already happened: Friend recommended it. Read a good review. Cover caught my eye. I can appreciate a cool cover. But it’s like the extra credit part of a test—it only enhances an already solid grade. Getting it right won’t help if most everything else is wrong. And getting it wrong won’t hurt if most everything else is right. (There are countless books I cherish whose covers I don’t like too much, or cannot even now recall.) The interior of the book—the terrain of its pages, where all those words took me, the tiny but very real spot it ultimately occupies in my mind—that becomes the book. Next I go to the flaps. The front flap needs to intrigue/not bore me, and the bio needs to tell me just enough about the author. I’ll do my best to extract the author’s entire existence from their 2-X-2 inch photo.Off to the back cover. I’ll be momentarily impressed when I see a blurb by a hot writer like ____, but I know that it is just as likely that I’ll like the book as hate it regardless of these quotes. I look at them in a more voyeuristic way, like a literary gaper’s delay: Wow, the author knows So and So. Bet they send each other clever text messages. Really the only thing I can gauge from the blurbs is my own pathetic jealousy level.To get a true sense of the book, I have to spend a minute inside. I’ll glance at the first couple pages, then flip to the middle, see if the language matches me somehow. It’s like dating, only with sentences. Some sentences, no matter how well-dressed or nice, just don’t do it for me. Others I click with instantly. It could be something as simple yet weirdly potent as a single word choice (tangerine). We’re meant to be, that sentence and me. And when it happens, you just know.

    She was a poor Southern tobacco farmer who worked the same land as her enslaved ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine. The first “immortal” human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. If you could pile all HeLa cells ever grown onto a scale, they’d weigh more than 50 million metric tons—as much as a hundred Empire State Buildings. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions.Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave.Now Rebecca Skloot takes us on an extraordinary journey, from the “colored” ward of Johns Hopkins Hospital in the 1950s to stark white laboratories with freezers full of HeLa cells; from Henrietta’s small, dying hometown of Clover, Virginia — a land of wooden quarters for enslaved people, faith healings, and voodoo — to East Baltimore today, where her children and grandchildren live and struggle with the legacy of her cells.Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family — past and present — is inextricably connected to the history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of.Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah, who was devastated to learn about her mother’s cells. She was consumed with questions: Had scientists cloned her mother? Did it hurt her when researchers infected her cells with viruses and shot them into space? What happened to her sister, Elsie, who died in a mental institution at the age of fifteen? And if her mother was so important to medicine, why couldn’t her children afford health insurance?Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.