Prusiner received a Nobel Prize, the world's most prestigious award for achievement in physiology or medicine. That he was the sole recipient of the award for the year was entirely appropriate, for his struggle to identify the agent responsible for ravaging the brains of animals suffering from scrapie and mad cow disease, and of humans with Creutzfeldt-Jakob disease, had been waged largely alone and in some cases in the face of strenuous disagreement.   In this book, Prusiner tells the remarkable story of his discovery of prions—infectious proteins that replicate and cause disease but surprisingly contain no genetic material—and reveals how superb and meticulous science is actually practiced using talented teams of researchers who persevere. He recounts the frustrations and rewards of years of research and offers fascinating portraits of his peers as they raced to discover the causes of fatal brain diseases. Prusiner’s hypothesis, once considered heresy, now stands as accepted science and the basis for developing diagnoses and eventual cures. He closes with a meditation on the legacy of his discovery: What will it take to cure Alzheimer’s, Parkinson’s, Lou Gehrig’s and other devastating diseases of the brain?

    Soon Gen Xers will be the only cohort of Americans who remember life as it was lived before the arrival of the Internet. They are, as Hennessey dubs them, “the last adult generation,” the sole remaining link to a time when childhood was still a bit dangerous but produced adults who were naturally resilient. More than a decade into the social media revolution, the American public is waking up to the idea that the tech sector’s intentions might not be as pure as advertised. The mountains of money being made off our browsing habits and purchase histories are used to fund ever-more extravagant and utopian projects that, by their very natures, will corrode the foundations of free society, leaving us all helpless and digitally enslaved to an elite crew of ultra-sophisticated tech geniuses. But it’s not too late to turn the tide. There’s still time for Gen X to write its own future. A spirited defense of free speech, eye contact, and the virtues of patience, Zero Hour for Gen X is a cultural history of the last 35 years, an analysis of the current social and historical moment, and a generational call to arms.

    Using graphics, checklists, and sample forms, this guide readies you for each step of the process, including selecting the committee, getting acclimated to academic writing, preparing for your oral defense, and publishing your research. New features include:A chapter on ethical considerations Expanded coverage of digital data collection and the Internet More detailed information on conducting the literature review A discussion of how to develop a theoretical or conceptual framework

    Ortner draws on her longstanding interest in theories of cultural practice to rethink key concepts of culture, agency, and subjectivity for the social sciences of the twenty-first century. The seven theoretical and interpretive essays in this volume each advocate reconfiguring, rather than abandoning, the concept of culture. Similarly, they all suggest that a theory which depends on the interested action of social beings—specifically practice theory, associated especially with the work of Pierre Bourdieu—requires a more developed notion of human agency and a richer conception of human subjectivity. Ortner shows how social theory must both build upon and move beyond classic practice theory in order to understand the contemporary world.Some of the essays reflect explicitly on theoretical concerns: the relationship between agency and power, the problematic quality of ethnographic studies of resistance, and the possibility of producing an anthropology of subjectivity. Others are ethnographic studies that apply Ortner’s theoretical framework. In these, she investigates aspects of social class, looking at the relationship between race and middle-class identity in the United States, the often invisible nature of class as a cultural identity and as an analytical category in social inquiry, and the role that public culture and media play in the creation of the class anxieties of Generation X. Written with Ortner’s characteristic lucidity, these essays constitute a major statement about the future of social theory from one of the leading anthropologists of our time.

    This contemporary and student-relevant text gives you all the key material you need for your introductory course, plus it will show you that anthropology is for you! With real world applications of the principles and practices of anthropology, this book will help you learn to appreciate other cultures as well as your own. Apply what you learn in this course to those situations that you are likely to encounter in your personal and professional life. What can you do with anthropology today? Check out the real-life examples of cross-cultural misunderstandings and issues (in our popular "Cross-Cultural Miscues" features) to view 'culture at work.' Also, the book takes a look at specialized vocabularies as illustrated by "chickspeak" (the language of single, urban, upwardly mobile women), the war in Iraq, environmental degradation, and other contemporary topics.

    

    Stephen Tow takes a second look at the music and community that vaulted the likes of Nirvana, Pearl Jam, Mudhoney, and Soundgarden to international fame. Chock-full of interviews with the starring characters, Tow extensively chronicles the rise of rock 'n' roll s last great statement and contextualizes what the music really meant to the key players. Delving deep into the archives, Tow paints a vivid picture of the underground rock circuit of tattered warehouses and community centers. Seattle s heady punk scene of the late '80s gave birth to a rowdy and raucous movement, influenced by metal, but wholly its own. Seattle made its own sound, a sound that came to be known internationally as grunge. Tow walks the reader through this sonic evolution, interviewing members of every band along the way. In 1991, Seattle s sound took the world by storm--but this same storm had been brewing in the Pacific Northwest for a decade before it hit MTV.The Strangest Tribeis a reframing of this last transformative era in music. Not just plaid shirts, bleached hair, and angst, grunge is a word used to describe a rich community of artists and jokers."

    Raised in a poor South London family with a history of mental illness, David Robert Jones was to become an emblem of his time whose fame rivaled that of Elvis Presley and the Beatles. He sang some of the most haunting pop songs of the 1970s and starred in some of the strangest plays and films of the period (The Elephant Man, The Hunger, The Man Who Fell to Earth). Androgynous, Jekyll and Hyde by turns, susceptible to cocaine and paranoia, casting off a series of managers and involved in complex lawsuits, Bowie eventually deserted Britain and America and moved to a house near the Berlin Wall. The Gillmans' formidable research enables them to smash many Bowie myths, but their sympathy for him and his disturbed family is evident, and they deal fairly with his wife, agents and lovers. Still, only obsessed Bowie fans will have the stamina to get all the way through this depressing 500-page odyssey. Photos. Copyright 1987 Reed Business Information, Inc.

    Joy White tells uncomfortable truths and blows apart our understanding of racism, crime and policing in our inner-cities.Since the 1980s, austerity, gentrification and structural racism have wreaked havoc on inner-city communities, widening inequality and entrenching poverty.In Terraformed, Joy White offers an insiders view of Forest Gate -- an urban neighbourhood in London -- analysing how these issues affect the black youth of today. Connecting the dots between music, politics and the built environment, it centres on the lived experiences of black youth who have had it all: huge student debt, invisible homelessness, custodial sentences, electronic tagging, surveillance, arrest, police brutality, issues with health and well-being, and of course, loss.Part ethnography, part memoir, Terraformed uses the history of Newham, London as an example of inner-city life across the globe and considers how young black lives are affected by racism, capitalism and austerity.

    Anselmi covers the bands and musicians that have impacted those styles most―Black Sabbath, Candlemass, Melvins, Eyehategod, Godflesh, Neurosis, Saint Vitus, and many others―while diving into the cultural doom that has spawned such music, from the bombing of Birmingham and hurricane devastation of New Orleans to glaring economic inequality, industrial alienation, climate change, and widespread addiction. Along the way, Anselmi interweaves the musical experiences that have led him to proudly identify as one of the doomed.

     Always straddling the fence between "po-po" and NYPD outsider, Derrick threatened police tradition to try to get the cases solved. He was the first detective to interview an informant offering a detailed account of Biggie Smalls's murder. He protected one of the only surviving eyewitnesses to the Jam Master Jay murder and knows the identity of the killers as well as the motivation behind the shooting. "Notorious C.O.P. "reveals hip-hop crimes that never made the paper--like the robbing of Foxy Brown and the first Hot 97 shooting--and answers some lingering questions about murders that have remained unsolved. The book that both the NYPD and the hip-hop community don't want you to read, "Notorious C.O.P. "is the first insider look at the real links between crime and hip-hop and the inefficiencies that have left some of the most widely publicized murders in entertainment history unsolved.

    Generations of theorists, however, have expunged life from their accounts, treating it as the mere output of patterns, codes, structures or systems variously defined as genetic or cultural, natural or social. Building on his classic work The Perception of the Environment, Tim Ingold sets out to restore life to where it should belong, at the heart of anthropological concern.Being Alive ranges over such themes as the vitality of materials, what it means to make things, the perception and formation of the ground, the mingling of earth and sky in the weather-world, the experiences of light, sound and feeling, the role of storytelling in the integration of knowledge, and the potential of drawing to unite observation and description.Our humanity, Ingold argues, does not come ready-made but is continually fashioned in our movements along ways of life. Starting from the idea of life as a process of wayfaring, Ingold presents a radically new understanding of movement, knowledge and description as dimensions not just of being in the world, but of being alive to what is going on there.

    It's a hard-bound, 898-page, full-color feast for the senses. Completists will get lost in thousands of freshly-manicured setlists, song histories, and charts. Prose junkies will binge on hundreds of evocative show reviews and fan stories. Photophiles will gape at 128 pages of dazzling Phish photography - most of which has never been published. And poster collectors, get ready: The Phish Companion's eight chapters are anchored by stunning original works from Welker, Masthay, Helton, and more - each of whom was commissioned to freely interpret a period of Phish. No need to wait in line before "doors" for this art. If that's not enough, the net proceeds of your purchase will benefit music education programs via grants from The Mockingbird Foundation. We firmly believe that music is not extracurricular, and we have seen first-hand how your generosity changes lives. Yes, the Phish story is one of epic sweep, but it's also personal. It's about the feeling that overtakes you when the lights go down and the roar comes up. Feel the feeling, right at your fingertips. Read The Book.

    From the woman suffering from "painful foot and moving toe syndrome" to the Indiana farmer who contacted a variant of mad cow disease from his herds of livestock, Klawans deduced a great deal from his patients, not only about the immediate causes of their ailments, but about the evolutionary underpinnings of their behavior.

    Rolling Stone ranked the Ramones at #26 on its list of the “100 Greatest Artists of All Time.” They received a Grammy Lifetime Achievement Award in 2011 and were inducted into the Rock ‘n’ Roll Hall of Fame in 2002. And Marky Ramone played a major part in this success—his “blitzkrieg” style of drumming drove the sound the Ramones pioneered. Now, fans can get the inside story.Before he joined the Ramones, Marc Bell was already a name in the New York music scene. But when he joined three other tough misfits, he became Marky Ramone, and the rhythm that came to epitomize punk was born.Having outlived his bandmates, Marky is the only person who can share the secrets and stories of the Ramones’ improbable rise from humble beginnings to induction into the Rock and Roll Hall of Fame. But it wasn’t all good times and hit songs, and Marky doesn’t shy away from discussing his own struggles for sobriety, including the addiction that led him to be temporarily kicked out of the band.From the cult film Rock ‘n’ Roll High School through “I Wanna Be Sedated” through his own struggle with alcoholism, Marky Ramone sets the record straight, painting an unflinching picture of the dysfunction behind the band that changed a generation. With exclusive behind-the-scenes photos, Pulsating to the Backbeat is both a cultural history of punk and a stirring story of addiction: the story that millions of fans have been waiting for.