Into the rarefied atmosphere of wealth and tradition comes the most unlikely of horses—a drab white former plow horse named Snowman—and his rider, Harry de Leyer. They were the longest of all longshots—and their win was the stuff of legend. Harry de Leyer first saw the horse he would name Snowman on a bleak winter afternoon between the slats of a rickety truck bound for the slaughterhouse. He recognized the spark in the eye of the beaten-up horse and bought him for eighty dollars. On Harry’s modest farm on Long Island, the horse thrived. But the recent Dutch immigrant and his growing family needed money, and Harry was always on the lookout for the perfect thoroughbred to train for the show-jumping circuit—so he reluctantly sold Snowman to a farm a few miles down the road. But Snowman had other ideas about what Harry needed. When he turned up back at Harry’s barn, dragging an old tire and a broken fence board, Harry knew that he had misjudged the horse. And so he set about teaching this shaggy, easygoing horse how to fly. One show at a time, against extraordinary odds and some of the most expensive thoroughbreds alive, the pair climbed to the very top of the sport of show jumping. Here is the dramatic and inspiring rise to stardom of an unlikely duo, based on the insight and recollections of “the Flying Dutchman” himself. Their story captured the heart of Cold War–era America—a story of unstoppable hope, inconceivable dreams, and the chance to have it all. Elizabeth Letts’s message is simple: Never give up, even when the obstacles seem sky-high. There is something extraordinary in all of us.

    Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings? A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.

    Eloquent and heartfelt."-- "Los Angeles Times"Of the many highly esteemed books Albert Schweitzer penned in his life, he valued his autobiography the most. He had become a legend and he wanted to remind readers that he was just a man, and a man who had learned from many others. He had been fortunate to be in the right places at the right times, to meet people of thought and sympathy. He wanted to report his debts to them. He wanted to clarify his reasons and methods for his undertakings and to respond to some of his critics. And, he wished to honor something greater than he was--reverence for life. Reverence for Life became his life's motto, and it brought him pain as well as joy as he sought to respect how precious and unique each life is. Schweitzer believed there was a way to live in the world, accept it, take joy from it--and who could know this better than a man who had placed himself so much in it, given so much for it, and had been ready to receive experience as a gift to be thankful for.In addition to a preface by Rhena Schweitzer Miller and Antje Bultmann Lemke, this translation incorporates revisions and additions Schweitzer made for the French translation of 1960 and those he made for thirty years in his own copy of the original German edition."This fascinating volume is the autobiography of the world-famous missionary doctor, organist, philosopher, theologian, and Nobel Peace Prize-winner, newly translated, researched, and corrected on the basis of recently discovered material."-- "Booklist""An authentic twentieth-century classic. Few books in our time have had a greater impact on the life and values of untold numbers of people."--Norman Cousins

    And as outbreaks of COVID-19, Ebola, MERS, and Zika have demonstrated, we are woefully underprepared to deal with the fallout. So what can -- and must -- we do in order to protect ourselves from mankind's deadliest enemy?Drawing on the latest medical science, case studies, policy research, and hard-earned epidemiological lessons, Deadliest Enemy explores the resources and programs we need to develop if we are to keep ourselves safe from infectious disease. The authors show how we could wake up to a reality in which many antibiotics no longer cure, bioterror is a certainty, and the threat of a disastrous influenza or coronavirus pandemic looms ever larger. Only by understanding the challenges we face can we prevent the unthinkable from becoming the inevitable.Deadliest Enemy is high scientific drama, a chronicle of medical mystery and discovery, a reality check, and a practical plan of action.

    Kennedy tells his extraordinary personal story--of his legendary family, politics, and fifty years at the center of national events.TRUE COMPASSThe youngest of nine children born to Joseph P. Kennedy and Rose Fitzgerald Kennedy, he came of age among siblings from whom much was expected. As a young man, he played a key role in the presidential campaign of his brother John F. Kennedy, recounted here in loving detail. In 1962 he was elected to the U.S. Senate, where he began a fascinating political education and became a legislator.In this historic memoir,Ted Kennedy takes us inside his family, re-creating life with his parents and brothers and explaining their profound impact on him. or the first time, he describes his heartbreak and years of struggle in the wake of their deaths. Through it all, he describes his work in the Senate on the major issues of our time--civil rights, Vietnam, Watergate, the quest for peace in Northern Ireland--and the cause of his life: improved health care for all Americans, a fight influenced by his own experiences in hospitals.His life has been marked by tragedy and perseverance, a love of family, and an abiding faith. There have been controversies, too, and Kennedy addresses them with unprecedented candor. At midlife, embattled and uncertain if he would ever fall in love again, he met the woman who changed his life, Victoria Reggie Kennedy. Facing a tough reelection campaign against an aggressive challenger named Mitt Romney, Kennedy found a new voice and began one of the great third acts in American politics, sponsoring major legislation, standing up for liberal principles, and making the pivotal endorsement of Barack Obama for president.Hundreds of books have been written about the Kennedys. TRUE COMPASS will endure as the definitive account from a member of America's most heralded family, an inspiring legacy to readers and to history, and a deeply moving story of a life like no other.

      Along the way, he reveals the untold story of Hans Asperger, the father of Asperger’s syndrome, whose “little professors” were targeted by the darkest social-engineering experiment in human history; exposes the covert campaign by child psychiatrist Leo Kanner to suppress knowledge of the autism spectrum for fifty years; and casts light on the growing movement of "neurodiversity" activists seeking respect, support, technological innovation, accommodations in the workplace and in education, and the right to self-determination for those with cognitive differences.

    ‘Sully’ Sullenberger—the pilot who miraculously landed a crippled US Airways Flight 1549 in New York’s Hudson River, saving the lives of all 155 passengers and crew.On January 15, 2009, the world witnessed a remarkable emergency landing when Captain "Sully" Sullenberger skillfully glided US Airways Flight 1549 onto the Hudson River, saving the lives of all 155 passengers and crew. His cool actions not only averted tragedy but made him a hero and an inspiration worldwide. His story is now a major motion picture from director / producer Clint Eastwood and stars Tom Hanks, Laura Linney and Aaron Eckhart.Sully's story is one of dedication, hope, and preparedness, revealing the important lessons he learned through his life, in his military service, and in his work as an airline pilot. It reminds us all that, even in these days of conflict, tragedy and uncertainty, there are values still worth fighting for—that life's challenges can be met if we're ready for them.

    Quickly becoming the biggest and most important medical initiative of the war, the project tasked dozens of the country’s top research scientists and university labs to find a treatment to remedy half a million U.S. troops incapacitated by malaria.Spearheading the new U.S. effort was Dr. Lowell T. Coggeshall, the son of a poor Indiana farmer whose persistent drive and curiosity led him to become one of the most innovative thinkers in solving the malaria problem. He recruited private corporations, such as today's Squibb and Eli Lilly, and the nation’s best chemists out of Harvard and Johns Hopkins to make novel compounds that skilled technicians tested on birds. Giants in the field of clinical research, including the future NIH director James Shannon, then tested the drugs on mental health patients and convicted criminals—including infamous murderer Nathan Leopold.By 1943, a dozen strains of malaria brought home in the veins of sick soldiers were injected into these human guinea pigs for drug studies. After hundreds of trials and many deaths, they found their “magic bullet,” but not in a U.S. laboratory. America 's best weapon against malaria, still used today, was captured in battle from the Nazis. Called chloroquine, it went on to save more lives than any other drug in history.Karen M. Masterson, a journalist turned malaria researcher, uncovers the complete story behind this dark tale of science, medicine and war. Illuminating, riveting and surprising, The Malaria Project captures the ethical perils of seeking treatments for disease while ignoring the human condition.

    At the heart of her story and abiding beliefs--her Jewish background. Tikkun olam, the Hebrew injunction to "repair the world," with its profound meaning for a young girl who grew up during the Holocaust and World War II. We see the influence of her mother, Celia Amster Bader, whose intellect inspired her daughter's feminism, insisting that Ruth become independent, as she witnessed her mother coping with terminal cervical cancer (Celia died the day before Ruth, at seventeen, graduated from high school). From Ruth's days as a baton twirler at Brooklyn's James Madison High School, to Cornell University, Harvard and Columbia Law Schools (first in her class), to being a law professor at Rutgers University (one of the few women in the field and fighting pay discrimination), hiding her second pregnancy so as not to risk losing her job; founding the Women's Rights Law Reporter, writing the brief for the first case that persuaded the Supreme Court to strike down a sex-discriminatory state law, then at Columbia (the law school's first tenured female professor); becoming the director of the women's rights project of the ACLU, persuading the Supreme Court in a series of decisions to ban laws that denied women full citizenship status with men. Her years on the U.S. Court of Appeals for the District of Columbia Circuit, deciding cases the way she played golf, as she, left-handed, played with right-handed clubs--aiming left, swinging right, hitting down the middle. Her years on the Supreme Court . . . A pioneering life and legal career whose profound mark on American jurisprudence, on American society, on our American character and spirit, will reverberate deep into the twenty-first century and beyond.

    Working in the kitchens of the upper class, she left a trail of disease in her wake, until one enterprising and ruthless “medical engineer” proposed the inconceivable notion of the “asymptomatic carrier”—and from then on Mary Mallon was a hunted woman. In order to keep New York’s citizens safe from Mallon, the Department of Health sent her to North Brother Island where she was kept in isolation from 1907-1910. She was released under the condition that she never work as a cook again. Yet for Mary—spoiled by her status and income and genuinely passionate about cooking—most domestic and factory jobs were heinous. She defied the edict.Bringing early twentieth-century New York alive—the neighborhoods, the bars, the park being carved out of upper Manhattan, the emerging skyscrapers, the boat traffic—Fever is as fiercely compelling as Typhoid Mary herself, an ambitious retelling of a forgotten life. In the hands of Mary Beth Keane, Mary Mallon becomes an extraordinarily dramatic, vexing, sympathetic, uncompromising, and unforgettable character.

    Heralded by Publishers Weekly as one of the best science books of the year, it is a provocative and deeply engaging book that elucidates the ties between a woman's experience of her vagina and her sense of self; her impulses, dreams, and courage; and her role in love and in society in completely new and revelatory ways sure to provoke impassioned conversation.A brilliant and nuanced synthesis of physiology, history, and cultural criticism, Vagina: A New Biography explores the physical, political, and spiritual implications of this startling series of new scientific breakthroughs for women and for society as a whole, from a writer whose conviction and keen intelligence have propelled her works to the tops of bestseller lists, and firmly into the realms of modern classics.

    It is essential reading for our times.In 28, Stephanie Nolen, the Globe and Mail’s Africa Bureau Chief, puts a human face to the crisis created by HIV-AIDS in Africa. She has achieved, in this amazing book, something extraordinary: she writes with a power, understanding and simplicity that makes us listen, makes us understand and care. Through riveting anecdotal stories – one for each of the million people living with HIV-AIDS in Africa – Nolen explores the effects of an epidemic that well exceeds the Black Plague in magnitude. It is a calamity that is unfolding just a 747-flight away, and one that will take the lives of these 28 million without the help of massive, immediate intervention on an unprecedented scale. 28 is a timely, transformative, thoroughly accessible book that shows us definitively why we continue to ignore the growth of HIV-AIDS in Africa only at our peril and at an intolerable moral cost.28’s stories are much more than a record of the suffering and loss in 28 emblematic lives. Here we meet women and men fighting vigorously on the frontlines of disease: Tigist Haile Michael, a smart, shy 14-year-old Ethiopian orphan fending for herself and her baby brother on the slum streets of Addis Ababa; Alice Kadzanja, an HIV-positive nurse in Malawi, where one in six adults has the virus, and where the average adult’s life expectancy is 36; and Zackie Achmat, the hero of South Africa’s politically fragmented battle against HIV-AIDS. 28 also tells us how the virus works, spreads and, ultimately, kills. It explains the connection of HIV-AIDS to conflict, famine and the collapse of states; shows us how easily treatment works for those lucky enough to get it and details the struggles of those who fight to stay alive with little support. It makes vivid the strong, desperate people doing all they can, and maintaining courage, dignity and hope against insurmountable odds. It is – in its humanity, beauty and sorrow – a call to action for all who read it.

    Engel seamlessly weaves together science, politics, and culture, writing with an even hand—noting the excesses of the more radical edges of the ACT UP movement as well as the conservative religious leaders who thought AIDS victims deserved what they got.The story of AIDS is one of the most compelling human dramas of our time, both in its profound tragedy and in the extraordinary scientific efforts impelled on its behalf. For gay Americans, it has been the story of the past generation, redefining the community and the community's sexuality. For the Third World, AIDS has created endless devastation, toppling economies, social structures, and whole villages and regions. And the worst may yet be to come: AIDS is expanding quickly into India, Russia, China, and elsewhere, while still raging insub-Saharan Africa.A distinguished medical historian, Engel lets his characters speak for themselves. Whether gay activists, government officials, public health professionals, scientists, or frightened parents of schoolchildren, they responded as best they could to tragic happenstance that emerged seemingly from nowhere. There is much drama here, and human weakness and heroism too. Writing with vivid immediacy, Engel allows us to relive the short but tumultuous history of a modern scourge.

    But one perspective has been missing up to this point—a 360-degree account of the day told through firsthand.Now, in The Only Plane in the Sky, Garrett Graff tells the story of the day as it was lived—in the words of those who lived it. Drawing on never-before-published transcripts, declassified documents, original interviews, and oral histories from nearly five hundred government officials, first responders, witnesses, survivors, friends, and family members, he paints the most vivid and human portrait of the September 11 attacks yet.Beginning in the predawn hours of airports in the Northeast, we meet the ticket agents who unknowingly usher terrorists onto their flights, and the flight attendants inside the hijacked planes. In New York, first responders confront a scene of unimaginable horror at the Twin Towers. From a secret bunker under the White House, officials watch for incoming planes on radar. Aboard unarmed fighter jets in the air, pilots make a pact to fly into a hijacked airliner if necessary to bring it down. In the skies above Pennsylvania, civilians aboard United 93 make the ultimate sacrifice in their place. Then, as the day moves forward and flights are grounded nationwide, Air Force One circles the country alone, its passengers isolated and afraid.More than simply a collection of eyewitness testimonies, The Only Plane in the Sky is the historic narrative of how ordinary people grappled with extraordinary events in real time: the father and son caught on different ends of the impact zone; the firefighter searching for his wife who works at the World Trade Center; the operator of in-flight telephone calls who promises to share a passenger’s last words with his family; the beloved FDNY chaplain who bravely performs last rites for the dying, losing his own life when the Towers collapse; and the generals at the Pentagon who break down and weep when they are barred from trying to rescue their colleagues.At once a powerful tribute to the courage of everyday Americans and an essential addition to the literature of 9/11, The Only Plane in the Sky weaves together the unforgettable personal experiences of the men and women who found themselves caught at the center of an unprecedented human drama. The result is a unique, profound, and searing exploration of humanity on a day that changed the course of history, and all of our lives.

    In The Demon in the Freezer, his first nonfiction book since The Hot Zone, a #1 New York Times bestseller, Richard Preston takes us into the heart of Usamriid, the United States Army Medical Research Institute of Infectious Diseases at Fort Detrick, Maryland, once the headquarters of the U.S. biological weapons program and now the epicenter of national biodefense.Peter Jahrling, the top scientist at Usamriid, a wry virologist who cut his teeth on Ebola, one of the world’s most lethal emerging viruses, has ORCON security clearance that gives him access to top secret information on bioweapons. His most urgent priority is to develop a drug that will take on smallpox-and win. Eradicated from the planet in 1979 in one of the great triumphs of modern science, the smallpox virus now resides, officially, in only two high-security freezers-at the Centers for Disease Control in Atlanta and in Siberia, at a Russian virology institute called Vector. But the demon in the freezer has been set loose. It is almost certain that illegal stocks are in the possession of hostile states, including Iraq and North Korea. Jahrling is haunted by the thought that biologists in secret labs are using genetic engineering to create a new superpox virus, a smallpox resistant to all vaccines.Usamriid went into a state of Delta Alert on September 11 and activated its emergency response teams when the first anthrax letters were opened in New York and Washington, D.C. Preston reports, in unprecedented detail, on the government’s response to the attacks and takes us into the ongoing FBI investigation. His story is based on interviews with top-level FBI agents and with Dr. Steven Hatfill.Jahrling is leading a team of scientists doing controversial experiments with live smallpox virus at CDC. Preston takes us into the lab where Jahrling is reawakening smallpox and explains, with cool and devastating precision, what may be at stake if his last bold experiment fails.