New emphasis has been given to complexity, networks, and patterns of organisation, leading to a novel kind of 'systemic' thinking. This volume integrates the ideas, models, and theories underlying the systems view of life into a single coherent framework. Taking a broad sweep through history and across scientific disciplines, the authors examine the appearance of key concepts such as autopoiesis, dissipative structures, social networks, and a systemic understanding of evolution. The implications of the systems view of life for health care, management, and our global ecological and economic crises are also discussed. Written primarily for undergraduates, it is also essential reading for graduate students and researchers interested in understanding the new systemic conception of life and its implications for a broad range of professions - from economics and politics to medicine, psychology and law.

    It recounts the life histories of those who had been victims of the 1920s encephalitis lethargica epidemic. Sacks chronicles his efforts in the late 1960s to help these patients at the Beth Abraham Hospital in the Bronx, New York.

    But what is it physically? And where is it really? Our mental map of the network is as blank as the map of the ocean that Columbus carried on his first Atlantic voyage. The Internet, its material nuts and bolts, is an unexplored territory. Until now.In Tubes, journalist Andrew Blum goes inside the Internet's physical infrastructure and flips on the lights, revealing an utterly fresh look at the online world we think we know. It is a shockingly tactile realm of unmarked compounds, populated by a special caste of engineer who pieces together our networks by hand; where glass fibers pulse with light and creaky telegraph buildings, tortuously rewired, become communication hubs once again. From the room in Los Angeles where the Internet first flickered to life to the caverns beneath Manhattan where new fiber-optic cable is buried; from the coast of Portugal, where a ten-thousand-mile undersea cable just two thumbs wide connects Europe and Africa, to the wilds of the Pacific Northwest, where Google, Microsoft, and Facebook have built monumental data centers—Blum chronicles the dramatic story of the Internet's development, explains how it all works, and takes the first-ever in-depth look inside its hidden monuments.This is a book about real places on the map: their sounds and smells, their storied pasts, their physical details, and the people who live there. For all the talk of the "placelessness" of our digital age, the Internet is as fixed in real, physical spaces as the railroad or telephone. You can map it and touch it, and you can visit it. Is the Internet in fact "a series of tubes" as Ted Stevens, the late senator from Alaska, once famously described it? How can we know the Internet's possibilities if we don't know its parts?Like Tracy Kidder's classic The Soul of a New Machine or Tom Vanderbilt's recent bestseller Traffic, Tubes combines on-the-ground reporting and lucid explanation into an engaging, mind-bending narrative to help us understand the physical world that underlies our digital lives.

    From the tenth to the fifteenth centuries the earth experienced a rise in surface temperature that changed climate worldwide—a preview of today's global warming. In some areas, including Western Europe, longer summers brought bountiful harvests and population growth that led to cultural flowering. In the Arctic, Inuit and Norse sailors made cultural connections across thousands of miles as they traded precious iron goods. Polynesian sailors, riding new wind patterns, were able to settle the remotest islands on earth. But in many parts of the world, the warm centuries brought drought and famine. Elaborate societies in western and central America collapsed, and the vast building complexes of Chaco Canyon and the Mayan Yucatan were left empty.As he did in his bestselling The Little Ice Age, anthropologist and historian Brian Fagan reveals how subtle changes in the environment had far-reaching effects on human life, in a narrative that sweeps from the Arctic ice cap to the Sahara to the Indian Ocean. The history of the Great Warming of a half millennium ago suggests that we may yet be underestimating the power of climate change to disrupt our lives today—and our vulnerability to drought, writes Fagan, is the "silent elephant in the room."Learn more at www.brianfagan.com.Brian Fagan discusses The Great Warming on The Daily Show with John Stewart.PRAISE for The Great Warming:"This is not only World History at its best, sweeping across all of humankind with a coherent vision, but also a feat of imagination and massive research. If Fagan has given the medieval period throughout the globe a new dimension, he has at the same time issued an irrefutable warning about climate change that is deeply troubling."—Theodore Rabb, author of The Last Days of the Renaissance"Climate has been making history for a very long time, though historians have rarely paid much attention to it. But as it turns out, a few less inches of rain, a change in temperature of just a degree or two can make all the difference in how human events unfold. The Great Warming demonstrates that although human beings make history, they very definitely do not make it under circumstances of their own choosing.”—Ted Steinberg, author of Down to Earth: Nature’s Role in American History and American Green: The Obsessive Quest for the Perfect Lawn

    In the great halls of science, dogma holds that Darwin's theory of natural selection explains every branch on the tree of life: which species thrive, which wither away to extinction, and what features each evolves. But can adaptation by natural selection really account for everything we see in nature? Yale University ornithologist Richard Prum--reviving Darwin's own views--thinks not. Deep in tropical jungles around the world are birds with a dizzying array of appearances and mating displays: Club-winged Manakins who sing with their wings, Great Argus Pheasants who dazzle prospective mates with a four-foot-wide cone of feathers covered in golden 3D spheres, Red-capped Manakins who moonwalk. In thirty years of fieldwork, Prum has seen numerous display traits that seem disconnected from, if not outright contrary to, selection for individual survival. To explain this, he dusts off Darwin's long-neglected theory of sexual selection in which the act of choosing a mate for purely aesthetic reasons--for the mere pleasure of it--is an independent engine of evolutionary change. Mate choice can drive ornamental traits from the constraints of adaptive evolution, allowing them to grow ever more elaborate. It also sets the stakes for sexual conflict, in which the sexual autonomy of the female evolves in response to male sexual control. Most crucially, this framework provides important insights into the evolution of human sexuality, particularly the ways in which female preferences have changed male bodies, and even maleness itself, through evolutionary time. The Evolution of Beauty presents a unique scientific vision for how nature's splendor contributes to a more complete understanding of evolution and of ourselves.

    Today’s "machine-learning" systems, trained by data, are so effective that we’ve invited them to see and hear for us?and to make decisions on our behalf. But alarm bells are ringing. Recent years have seen an eruption of concern as the field of machine learning advances. When the systems we attempt to teach will not, in the end, do what we want or what we expect, ethical and potentially existential risks emerge. Researchers call this the alignment problem.Systems cull résumés until, years later, we discover that they have inherent gender biases. Algorithms decide bail and parole?and appear to assess Black and White defendants differently. We can no longer assume that our mortgage application, or even our medical tests, will be seen by human eyes. And as autonomous vehicles share our streets, we are increasingly putting our lives in their hands.The mathematical and computational models driving these changes range in complexity from something that can fit on a spreadsheet to a complex system that might credibly be called “artificial intelligence.” They are steadily replacing both human judgment and explicitly programmed software.In best-selling author Brian Christian’s riveting account, we meet the alignment problem’s “first-responders,” and learn their ambitious plan to solve it before our hands are completely off the wheel. In a masterful blend of history and on-the ground reporting, Christian traces the explosive growth in the field of machine learning and surveys its current, sprawling frontier. Readers encounter a discipline finding its legs amid exhilarating and sometimes terrifying progress. Whether they—and we—succeed or fail in solving the alignment problem will be a defining human story.The Alignment Problem offers an unflinching reckoning with humanity’s biases and blind spots, our own unstated assumptions and often contradictory goals. A dazzlingly interdisciplinary work, it takes a hard look not only at our technology but at our culture—and finds a story by turns harrowing and hopeful.

    Nuclear devastation. Bio-hazards. The Large Hadron Collider. What do these things have in common? They all have the potential to end our world. Every great scientific creation of man is balanced by an equal amount of danger—as there’s no progress without risk. Armageddon Science is an authoritative look at the real “mad science” at work today, that recklessly puts life on Earth at risk for the pursuit of knowledge and personal gain. This book explores the reality of the dangers that science poses to the human race, from the classic fear of nuclear destruction to the latest possibilities for annihilation. Combining the science behind those threats with an understanding of the real people responsible as well as providing an assessment of the likelihood of the end of the world, this isn’t a disaster movie, it’s Armageddon Science.

    Peter H. Duesberg argues that HIV is merely a harmless passenger virus that does not cause AIDS. Sure to spark intense debate, this provocative book offers an original and incisive critique of the rise and fall of HIV.

    It is a waste product and a commodity pricier than oil. It can save lives and transmit deadly infections. Each one of us has roughly nine pints of it, yet many don’t even know their own blood type. And for all its ubiquity, the few tablespoons of blood discharged by 800 million women are still regarded as taboo; menstruation is perhaps the single most demonized biological event.Rose George, author of The Big Necessity, is renowned for her intrepid work on topics that are invisible but vitally important. In Nine Pints, she takes us from ancient practices of bloodletting to modern “hemovigilance” teams that track blood-borne diseases. She introduces Janet Vaughan, who set up the world’s first system of mass blood donation during the Blitz, and Arunachalam Muruganantham, known as “Menstrual Man” for his work on sanitary pads for developing countries. She probes the lucrative business of plasma transfusions, in which the U.S. is known as the “OPEC of plasma.” And she looks to the future, as researchers seek to bring synthetic blood to a hospital near you.Spanning science and politics, stories and global epidemics, Nine Pints reveals our life's blood in an entirely new light.

    Her story and others like it show that humans are not the only species with the capacity for love, hate, fear, shame, guilt, joy, disgust, and empathy, and open our hearts and minds to the many ways in which humans and other animals are connected. “Through colorful stories and riveting prose, de Waal firmly puts to rest the stubborn notion that humans alone in the animal kingdom experience a broad array of emotions.” — Barbara J. King, NPR“De Waal’s eye- opening observations argue for better treatment and greater appreciation of animals, even as he ensures that you’ll never look at them—or yourself—the same way again.” — People

    But if we are supposedly evolution’s greatest creation, why do we have such bad knees? Why do we catch head colds so often—two hundred times more often than a dog does? How come our wrists have so many useless bones? Why is the vast majority of our genetic code pointless? And are we really supposed to swallow and breathe through the same narrow tube? Surely there’s been some kind of mistake. As professor of biology Nathan H. Lents explains in Human Errors, our evolutionary history is nothing if not a litany of mistakes, each more entertaining and enlightening than the last. The human body is one big pile of compromises. But that is also a testament to our greatness: as Lents shows, humans have so many design flaws precisely because we are very, very good at getting around them.   A rollicking, deeply informative tour of humans’ four billion year long evolutionary saga, Human Errors both celebrates our imperfections and offers an unconventional accounting of the cost of our success.

    And yet we have sacrificed conversation for mere connection. Preeminent author and researcher Sherry Turkle has been studying digital culture for over thirty years. Long an enthusiast for its possibilities, here she investigates a troubling consequence: at work, at home, in politics, and in love, we find ways around conversation, tempted by the possibilities of a text or an email in which we don’t have to look, listen, or reveal ourselves. We develop a taste for what mere connection offers. The dinner table falls silent as children compete with phones for their parents’ attention. Friends learn strategies to keep conversations going when only a few people are looking up from their phones. At work, we retreat to our screens although it is conversation at the water cooler that increases not only productivity but commitment to work. Online, we only want to share opinions that our followers will agree with – a politics that shies away from the real conflicts and solutions of the public square. The case for conversation begins with the necessary conversations of solitude and self-reflection. They are endangered: these days, always connected, we see loneliness as a problem that technology should solve. Afraid of being alone, we rely on other people to give us a sense of ourselves, and our capacity for empathy and relationship suffers. We see the costs of the flight from conversation everywhere: conversation is the cornerstone for democracy and in business it is good for the bottom line. In the private sphere, it builds empathy, friendship, love, learning, and productivity. But there is good news: we are resilient. Conversation cures. Based on five years of research and interviews in homes, schools, and the workplace, Turkle argues that we have come to a better understanding of where our technology can and cannot take us and that the time is right to reclaim conversation. The most human—and humanizing—thing that we do. The virtues of person-to-person conversation are timeless, and our most basic technology, talk, responds to our modern challenges. We have everything we need to start, we have each other.

    But are there limits to what we can discover about our physical universe?In this very personal journey to the edges of knowledge, Marcus du Sautoy investigates how leading experts in fields from quantum physics and cosmology, to sensory perception and neuroscience, have articulated the current lie of the land. In doing so, he travels to the very boundaries of understanding, questioning contradictory stories and consulting cutting edge data.Is it possible that we will one day know everything? Or are there fields of research that will always lie beyond the bounds of human comprehension? And if so, how do we cope with living in a universe where there are things that will forever transcend our understanding?In What We Cannot Know, Marcus du Sautoy leads us on a thought-provoking expedition to the furthest reaches of modern science. Prepare to be taken to the edge of knowledge to find out if there’s anything we truly cannot know.

    We see it, touch it, and live in it every day. It is a habitat for a mesmerizingly complex world of micro-organisms and physical functions that are vital to our health and our survival. It is also a waste removal plant, a warning system for underlying disease and a dynamic immune barrier to infection. One of the first things people see about us, skin is crucial to our sense of identity, providing us with social significance and psychological meaning. And yet our skin and the fascinating way it functions is largely unknown to us. In prose as lucid as his research underlying it is rigorous, blending in memorable stories from the past and from his own medical experience, Monty Lyman has written a revelatory book exploring our outer surface that will surprise and enlighten in equal measure. Through the lenses of science, sociology, and history--on topics as diverse as the mechanics and magic of touch (how much goes on in the simple act of taking keys out of a pocket and unlocking a door is astounding), the close connection between the skin and the gut, what happens instantly when one gets a paper cut, and how a midnight snack can lead to sunburn--Lyman leads us on a journey across our most underrated and unexplored organ and reveals how our skin is far stranger, more wondrous, and more complex than we have ever imagined.

    Gut, an international bestseller, gives the alimentary canal its long-overdue moment in the spotlight. With quirky charm, rising science star Giulia Enders explains the gut’s magic, answering questions like: Why does acid reflux happen? What’s really up with gluten and lactose intolerance? How does the gut affect obesity and mood? Communication between the gut and the brain is one of the fastest-growing areas of medical research—on par with stem-cell research. Our gut reactions, we learn, are intimately connected with our physical and mental well-being. Enders’s beguiling manifesto will make you finally listen to those butterflies in your stomach: they’re trying to tell you something important.