Proven with mathematics this book describes genuine ancient knowledge that conflicts with modern science but upholds the Biblical story of Genesis.

    The Eighth Edition has been thoroughly revised and updated and is available in both print and e-book formats.Janeway s Immunobiology continues to set the standard for currency and authority with its clear writing style and organization, uniform art program, and scientific accuracy. It presents a consistent point of view throughout that of the host s interaction with an environment containing many species of potentially harmful microorganisms. The full-color art program is conceptually coherent and illustrates the processes and mechanisms underlying the concepts in the text. The 16 chapters in this readable, accessible textbook are organized and presented in such a way as to help deliver a complete one-semester immunology course, beginning with innate immunity, then moving to adaptive immunity, and ending with applied clinical immunology.Discussion questions are provided at the end of Chapters 2 to 16. These questions can be used for review, or as the basis for discussion in class or in informal study groups. Summaries conclude each section and each chapter. As in previous editions, a caduceus icon in the margins indicates topics which are correlated to Case Studies in Immunology, Sixth Edition by Geha and Notarangelo.New in the Eighth EditionInnate immunity has been updated and expanded and is now presented in two separate chapters (Chapters 2 and 3), as well as being further emphasized in the rest of the textbook. Chapter 2 covers antimicrobial peptides and the complement system, and Chapter 3 deals with cellular innate receptors and cell-mediated innate immunity (e.g. TLRs, phagocytosis, NK cells, interferon production, innate-like lymphocytes). The section on complement has been reworked and reconceived explaining the lectin pathway first making it easier to teach by placing it into the context of innate recognition. Evolution is now incorporated throughout the text, helping students see similar strategies used by different organisms. The text and figures of Chapter 7 Signaling Through Immune System Receptors have been revised to present a cohesive synthesis of signaling for immunology, focusing on improved illustration of antigen recognition signaling and lymphocyte activation. Signaling through other receptors is dealt with wherever appropriate throughout the book. Updated chapter on B-cell immune responses (Chapter 10), especially on trafficking of B cells in peripheral lymphoid organs (e.g. lymph nodes) and the locations at which they encounter antigen. Coverage of mucosal immunity (Chapter 12) has been brought up to date, including responses to the commensal microbiota and the role of specialized dendritic cells and the regulatory T cells in maintaining tolerance to food antigens and commensal bacteria. Chapter 13, Failures of Host Defense Mechanisms, has been reorganized and revised to structure an understanding of primary immunodeficiencies in the context of developmental pathways. Chapter 16, Manipulation of the Immune Response, has been heavily revised to include a greater emphasis on clinical issues and a complete update of immunotherapeutics and vaccines. Many new and revised figures illustrate the processes and mechanisms underlying the concepts presented in the text. The icons used have been updated and expanded to incorporate a new emphasis on signaling pathways. New references have been added throughout the text.

    What happened, how it happened, and what it means to you today. A colorful cast of characters whose discoveries were often driven not only by personal tragedy, curiosity, and hard work, but petty bickering, dumb luck, and a healthy dose of humor. For anyone interested in science, medicine, and beyond... Why are you alive right now? Chances are, you owe your life to one of the remarkable medical discoveries in this book. Maybe it was vaccines. Or antibiotics. Or X-rays. Revolutionary medical breakthroughs like these haven’t just changed the way we treat disease, they’ve transformed how we understand ourselves and the world we live in. In Breakthrough!, Jon Queijo tells the hidden stories behind 10 of history’s most amazing medical discoveries. This isn’t dry history: These are life-and-death mysteries uncovered, tales of passionate, often-mocked individuals who stood their ground and were proven right. From germs to genetics, the ancient Hippocrates to the cutting edge, these are stories that have changed the world—and, quite likely, saved your life.

    It's ever-present. Without it, you would die in minutes. And it has an epic story to tell.In Caesar's Last Breath, New York Times bestselling author Sam Kean takes us on a journey through the periodic table, around the globe, and across time to tell the story of the air we breathe, which, it turns out, is also the story of earth and our existence on it.With every breath, you literally inhale the history of the world. On the ides of March, 44 BC, Julius Caesar died of stab wounds on the Senate floor, but the story of his last breath is still unfolding; in fact, you're probably inhaling some of it now. Of the sextillions of molecules entering or leaving your lungs at this moment, some might well bear traces of Cleopatra's perfumes, German mustard gas, particles exhaled by dinosaurs or emitted by atomic bombs, even remnants of stardust from the universe's creation.Tracing the origins and ingredients of our atmosphere, Kean reveals how the alchemy of air reshaped our continents, steered human progress, powered revolutions, and continues to influence everything we do. Along the way, we'll swim with radioactive pigs, witness the most important chemical reactions humans have discovered, and join the crowd at the Moulin Rouge for some of the crudest performance art of all time. Lively, witty, and filled with the astounding science of ordinary life, Caesar's Last Breath illuminates the science stories swirling around us every second.

    In this unconventional introduction, physicist Leonard Susskind and hacker-scientist George Hrabovsky offer a first course in physics and associated math for the ardent amateur. Unlike most popular physics books—which give readers a taste of what physicists know but shy away from equations or math—Susskind and Hrabovsky actually teach the skills you need to do physics, beginning with classical mechanics, yourself. Based on Susskind's enormously popular Stanford University-based (and YouTube-featured) continuing-education course, the authors cover the minimum—the theoretical minimum of the title—that readers need to master to study more advanced topics.An alternative to the conventional go-to-college method, The Theoretical Minimum provides a tool kit for amateur scientists to learn physics at their own pace.

    Throughout his celebrated career, Schaller has spent more time in Tibet than in any other part of the world, devoting more than thirty years to the wildlife, culture, and landscapes that captured his heart and continue to compel him to protect them.  Tibet Wild is Schaller’s account of three decades of exploration in the most remote stretches of Tibet: the wide, sweeping rangelands of the Chang Tang and the hidden canyons and plunging ravines of the southeastern forests. As engaging as he is enlightening, Schaller illustrates the daily struggles of a field biologist trying to traverse the impenetrable Chang Tang, discover the calving grounds of the chiru or Tibetan antelope, and understand the movements of the enigmatic snow leopard.    As changes in the region accelerated over the years, with more roads, homes, and grazing livestock, Schaller watched the clash between wildlife and people become more common—and more destructive. Thus what began as a purely scientific endeavor became a mission: to work with local communities, regional leaders, and national governments to protect the unique ecological richness and culture of the Tibetan Plateau.    Whether tracking brown bears, penning fables about the tiny pika, or promoting a conservation preserve that spans the borders of four nations, Schaller has pursued his goal with a persistence and good humor that will inform and charm readers.  Tibet Wild is an intimate journey through the changing wilderness of Tibet, guided by the careful gaze and unwavering passion of a life-long naturalist.

    Supersized life spans are going to radically alter society, and present an unprecedented opportunity to change our approach not only to old age but to all of life’s stages. The ramifications are just beginning to dawn on us.... yet in the meantime, we keep thinking about, and planning for, life as it used to be lived. In A Long Bright Future, longevity and aging expert Laura Carstensen guides us into the new possibilities offered by a longer life. She debunks the myths and misconceptions about aging that stop us from adequately preparing for the future both as individuals and as a society: that growing older is associated with loneliness and unhappiness, and that only the genetically blessed live well and long. She then focuses on other important components of a long life, including finances, health, social relationships, Medicare and Social Security, challenging our preconceived notions of “old age” every step of the way.

    Emphasis is placed on connections in nature, the importance of ecology to environmental health and services, and links to evolution.

    Alice Dreger focuses on events in France and Britain in the late nineteenth century, a moment of great tension for questions of sex roles. While feminists, homosexuals, and anthropological explorers openly questioned the natures and purposes of the two sexes, anatomical hermaphrodites suggested a deeper question: just how many human sexes are there? Ultimately hermaphrodites led doctors and scientists to another surprisingly difficult question: what is sex, really?Hermaphrodites and the Medical Invention of Sex takes us inside the doctors' chambers to see how and why medical and scientific men constructed sex, gender, and sexuality as they did, and especially how the material conformation of hermaphroditic bodies--when combined with social exigencies--forced peculiar constructions. Throughout the book Dreger indicates how this history can help us to understand present-day conceptualizations of sex, gender, and sexuality. This leads to an epilogue, where the author discusses and questions the protocols employed today in the treatment of intersexuals (people born hermaphroditic). Given the history she has recounted, should these protocols be reconsidered and revised?A meticulously researched account of a fascinating problem in the history of medicine, this book will compel the attention of historians, physicians, medical ethicists, intersexuals themselves, and anyone interested in the meanings and foundations of sexual identity.

    

    But, despite appearances, these are not dogs—they are foxes. They are the result of the most astonishing experiment in breeding ever undertaken—imagine speeding up thousands of years of evolution into a few decades. In 1959, biologists Dmitri Belyaev and Lyudmila Trut set out to do just that, by starting with a few dozen silver foxes from fox farms in the USSR and attempting to recreate the evolution of wolves into dogs in real time in order to witness the process of domestication. This is the extraordinary, untold story of this remarkable undertaking. Most accounts of the natural evolution of wolves place it over a span of about 15,000 years, but within a decade, Belyaev and Trut’s fox breeding experiments had resulted in puppy-like foxes with floppy ears, piebald spots, and curly tails. Along with these physical changes came genetic and behavioral changes, as well. The foxes were bred using selection criteria for tameness, and with each generation, they became increasingly interested in human companionship. Trut has been there the whole time, and has been the lead scientist on this work since Belyaev’s death in 1985, and with Lee Dugatkin, biologist and science writer, she tells the story of the adventure, science, politics, and love behind it all.  In How to Tame a Fox, Dugatkin and Trut take us inside this path-breaking experiment in the midst of the brutal winters of Siberia to reveal how scientific history is made and continues to be made today. To date, fifty-six generations of foxes have been domesticated, and we continue to learn significant lessons from them about the genetic and behavioral evolution of domesticated animals. How to Tame a Fox offers an incredible tale of scientists at work, while also celebrating the deep attachments that have brought humans and animals together throughout time.

    This elegant, humane, and engaging book "captures what we know of the development of what makes us human" (Nature).Visit Armand Marie Leroi on the web: http: //armandleroi.com/index.htmlStepping effortlessly from myth to cutting-edge science,

    The 4 quilts in this pattern use 1 big block to make quilts that are about 45 inches square finished. The units for these quilts include four patches, nine patches, half square triangles and tri square triangles.

    Updated atlas contains maps of every U.S. state that are 35% larger than the standard atlas version plus over 350 detailed city inset and national park maps and a comprehensive, unabridged index. Road construction projects and updates highlighted for every state and conveniently located above the maps. Contains mileage chart showing distances between 77 North American cities and national parks with driving times map. Tough spiral binding allows the book to lay open easily. Other Features Best of the Road - Our editor's favorite road trips from our Best of the Road collection follows scenic routes along stretches of coastline, both east and west, to forests mountains, and prairies; and through small towns and big cities. For a weekend or a week there's something for everyone. Tell Rand! As much as we work to keep our atlases up to date, conditions change quickly and new construction projects begin frequently. If you know of something we haven't captured in our atlas, let us know at randmcnally.com/tellrand. Tourism websites and phone numbers for every U.S. state and Canadian province on map pages

    This Rosary tool has also been consistently in the Amazon top ten best selling books of Prayer since every month since its release; this includes paperback and kindle prayer books. Buy with confidence and may it enhance your opportunity to pray to Our Lady.This is a tool to allow you to use your Kindle to pray the rosary. This version of the rosary is intended to allow for praying the rosary with the turn of each page acting as a rosary bead. It contains all four rosary mysteries Joyful, Sorrowful, Glorious, and Luminous. The table of contents will allow you to jump to any of the four mysteries. Given that the Kindle, Nook, and other eBook devices allow thousands of books to be carried within them, it makes sense that the most powerful prayer in the world should also be included. Turning one page for each bead of the rosary makes the device feel and respond like a rosary necklace. Praying the rosary is an art which includes a certain rhythm of changing beads and prayers while in contemplation. Other rosary books either teach the prayers or outline the process but don’t account for the rhythm an art of contemplation that the process itself supports. This version allows that process to be integrated into the book itself; no beads required. While I personally love rosary beads, I don’t always have them available. I also like having the precise bible scriptures associated with each Mystery integrated into the process itself; it allows a more detailed focus by reading the actual living word of God without losing rhythm. While I personally know what the mysteries are about and what each decade story is, it adds a bit of opportunity to read in detail the bible passages of each mystery while not breaking stride with the prayer process. And, if there is ever a moment of distraction by events around me, I never lose my exact spot in praying the rosary.I pray that this book enhances opportunity for you to pray the rosary on many occasions when otherwise you may not have, and I hope it enhances your prayers on a regular basis through deeper connection with the scriptures which are the living word of God. The following updates were made based on user recommendations:VERSION UPDATED JULY 22, 2012 - Changed the table of contents to show the correct day for Luminous Mysteries to be prayed 'Thursday', updated the Glory Be prayer to be included after the first 3 Hail Mary's at the opening of each Mystery, Updated the Glory Be to be worded more technically correct.VERSION UPDATED DECEMBER 11, 2011 - Changed language of Apostle's Creed to match Catholic Church New Translation, fixed misspelled word "beech" to read "beseech", fixed missing bible verse for Mysteries "crowning with thorns" and "coronation of mary".