That is until 1904, when the disease broke out in a household in Oyster Bay, Long Island. Authorities suspected the family cook, Mary Mallon, of being a carrier. But before she could be tested, the woman, soon to be known as Typhoid Mary, had disappeared. Over the course of the next three years, Mary worked at several residences, spreading her pestilence as she went. In 1907, she was traced to a home on Park Avenue, and taken into custody. Institutionalized at Riverside Hospital for three years, she was released only when she promised never to work as a cook again. She promptly disappeared.For the next five years Mary worked in homes and institutions in and around New York, often under assumed names. In February 1915, a devastating outbreak of typhoid at the Sloane Hospital for Women was traced to her. She was finally apprehended and reinstitutionalized at Riverside Hospital, where she would remain for the rest of her life.Typhoid Mary is the story of her infamous life. Anthony Bourdain reveals the seedier side of the early 1900s, and writes with his renowned panache about life in the kitchen, uncovering the horrifying conditions that allowed the deadly spread of typhoid over a decade. Typhoid Mary is a true feast for history lovers and Bourdain lovers alike.

    Sharon Moalem turns our current understanding of illness on its head and challenges us to fundamentally change the way we think about our bodies, our health, and our relationship to just about every other living thing on earth, from plants and animals to insects and bacteria.Through a fresh and engaging examination of our evolutionary history, Dr. Moalem reveals how many of the conditions that are diseases today actually gave our ancestors a leg up in the survival sweepstakes. When the option is a long life with a disease or a short one without it, evolution opts for disease almost every time.Everything from the climate our ancestors lived in to the crops they planted and ate to their beverage of choice can be seen in our genetic inheritance. But Survival of the Sickest doesn't stop there. It goes on to demonstrate just how little modern medicine really understands about human health, and offers a new way of thinking that can help all of us live longer, healthier lives..

    In this sensational and macabre story, we meet the surgeon who counted not only luminaries Benjamin Franklin, Lord Byron, Adam Smith, and Thomas Gainsborough among his patients but also “resurrection men” among his close acquaintances. A captivating portrait of his ruthless devotion to uncovering the secrets of the human body, and the extraordinary lengths to which he went to do so—including body snatching, performing pioneering medical experiments, and infecting himself with venereal disease—this rich historical narrative at last acknowledges this fascinating man and the debt we owe him today.

    Complications lays bare a science not in its idealized form but as it actually is--uncertain, perplexing, and profoundly human.Complications is a 2002 National Book Award Finalist for Nonfiction.

    Lies My Teacher Told Me won the American Book Award and the Oliver Cromwell Cox Award for Distinguished Anti-Racist Scholarship.James W. Loewen, a sociology professor and distinguished critic of history education, puts 12 popular textbooks under the microscope-and what he discovers will surprise you. In his opinion, every one of these texts fails to make its subject interesting or memorable. Worse still is the proliferation of blind patriotism, mindless optimism and misinformation filling the pages.From the truth about Christopher Columbus to the harsh reality of the Vietnam War, Loewen picks apart the lies we've been told. This audiobook, narrated by Brian Keeler (The Hurricane, "All My Children") will forever change your view of the past.

    Lisa Sanders, author of the monthly New York Times Magazine column "Diagnosis," the inspiration for the hit Fox TV series House, M.D.The experience of being ill can be like waking up in a foreign country. Life, as you formerly knew it, is on hold while you travel through this other world as unknown as it is unexpected. When I see patients in the hospital or in my office who are suddenly, surprisingly ill, what they really want to know is, ‘What is wrong with me?’ They want a road map that will help them manage their new surroundings. The ability to give this unnerving and unfamiliar place a name, to know it–on some level–restores a measure of control, independent of whether or not that diagnosis comes attached to a cure. Because, even today, a diagnosis is frequently all a good doctor has to offer.A healthy young man suddenly loses his memory–making him unable to remember the events of each passing hour. Two patients diagnosed with Lyme disease improve after antibiotic treatment–only to have their symptoms mysteriously return. A young woman lies dying in the ICU–bleeding, jaundiced, incoherent–and none of her doctors know what is killing her. In Every Patient Tells a Story, Dr. Lisa Sanders takes us bedside to witness the process of solving these and other diagnostic dilemmas, providing a firsthand account of the expertise and intuition that lead a doctor to make the right diagnosis.Never in human history have doctors had the knowledge, the tools, and the skills that they have today to diagnose illness and disease. And yet mistakes are made, diagnoses missed, symptoms or tests misunderstood. In this high-tech world of modern medicine, Sanders shows us that knowledge, while essential, is not sufficient to unravel the complexities of illness. She presents an unflinching look inside the detective story that marks nearly every illness–the diagnosis–revealing the combination of uncertainty and intrigue that doctors face when confronting patients who are sick or dying. Through dramatic stories of patients with baffling symptoms, Sanders portrays the absolute necessity and surprising difficulties of getting the patient’s story, the challenges of the physical exam, the pitfalls of doctor-to-doctor communication, the vagaries of tests, and the near calamity of diagnostic errors. In Every Patient Tells a Story, Dr. Sanders chronicles the real-life drama of doctors solving these difficult medical mysteries that not only illustrate the art and science of diagnosis, but often save the patients’ lives.

    Operations on the brain carry grave risks. Every day, leading neurosurgeon Henry Marsh must make agonizing decisions, often in the face of great urgency and uncertainty.If you believe that brain surgery is a precise and exquisite craft, practiced by calm and detached doctors, this gripping, brutally honest account will make you think again. With astonishing compassion and candor, Marsh reveals the fierce joy of operating, the profoundly moving triumphs, the harrowing disasters, the haunting regrets, and the moments of black humor that characterize a brain surgeon's life.Do No Harm provides unforgettable insight into the countless human dramas that take place in a busy modern hospital. Above all, it is a lesson in the need for hope when faced with life's most difficult decisions.

    And so, in this rich and original work that explores the Gulf through our human connection with the sea, environmental historian Jack E. Davis finally places this exceptional region into the American mythos in a sweeping history that extends from the Pleistocene age to the twenty-first century.Significant beyond tragic oil spills and hurricanes, the Gulf has historically been one of the world's most bounteous marine environments, supporting human life for millennia. Davis starts from the premise that nature lies at the center of human existence, and takes readers on a compelling and, at times, wrenching journey from the Florida Keys to the Texas Rio Grande, along marshy shorelines and majestic estuarine bays, profoundly beautiful and life-giving, though fated to exploitation by esurient oil men and real-estate developers.Rich in vivid, previously untold stories, The Gulf tells the larger narrative of the American Sea—from the sportfish that brought the earliest tourists to Gulf shores to Hollywood’s engagement with the first offshore oil wells—as it inspired and empowered, sometimes to its own detriment, the ethnically diverse groups of a growing nation. Davis' pageant of historical characters is vast, including: the presidents who directed western expansion toward its shores, the New England fishers who introduced their own distinct skills to the region, and the industries and big agriculture that sent their contamination downstream into the estuarine wonderland. Nor does Davis neglect the colorfully idiosyncratic individuals: the Tabasco king who devoted his life to wildlife conservation, the Texas shrimper who gave hers to clean water and public health, as well as the New York architect who hooked the “big one” that set the sportfishing world on fire.Ultimately, Davis reminds us that amidst the ruin, beauty awaits its return, as the Gulf is, and has always been, an ongoing story. Sensitive to the imminent effects of climate change, and to the difficult task of rectifying grievous assaults of recent centuries, The Gulf suggests how a penetrating examination of a single region's history can inform the country's path ahead.

    The lifesaving serum was a thousand miles away, the port was icebound, and planes couldn't fly in blizzard conditions—only the dogs could make it. The heroic dash of dog teams across the Alaskan wilderness to Nome inspired the annual Iditarod Trail Sled Dog Race and immortalized Balto, the lead dog of the last team whose bronze statue still stands in New York City's Central Park. This is the greatest dog story, never fully told until now.

    is the first deep-dive investigation of a hazardous and illicit industry that has created a worldwide epidemic, ravaging communities and overwhelming and confounding government agencies that are challenged to combat it. "A whole new crop of chemicals is radically changing the recreational drug landscape," writes Ben Westhoff. "These are known as Novel Psychoactive Substances (NPS) and they include replacements for known drugs like heroin, cocaine, ecstasy, and marijuana. They are synthetic, made in a laboratory, and are much more potent than traditional drugs"--and all-too-often tragically lethal. Drugs like fentanyl, K2, and Spice--and those with arcane acronyms like 25i-NBOMe-- were all originally conceived in legitimate laboratories for proper scientific and medicinal purposes. Their formulas were then hijacked and manufactured by rogue chemists, largely in China, who change their molecular structures to stay ahead of the law, making the drugs' effects impossible to predict. Westhoff has infiltrated this shadowy world, becoming the first journalist to report from inside an illicit Chinese fentanyls lab and providing startling and original reporting on how China's vast chemical industry operates, and how the Chinese government subsidizes it. He tracks down the little-known scientists who invented these drugs and inadvertently killed thousands, as well as a mysterious drug baron who turned the law upside down in his home country of New Zealand. Poignantly, Westhoff chronicles the lives of addicted users and dealers, families of victims, law enforcement officers, and underground drug awareness organizers in the U.S. and Europe. Together they represent the shocking and riveting full anatomy of a calamity we are just beginning to understand. From its depths, as Westhoff relates, are emerging new strategies that may provide essential long-term solutions to the drug crisis that has affected so many.

    Foner begins with Lincoln's youth in Indiana and Illinois and follows the trajectory of his career across an increasingly tense and shifting political terrain from Illinois to Washington, D.C. Although “naturally anti-slavery” for as long as he can remember, Lincoln scrupulously holds to the position that the Constitution protects the institution in the original slave states. But the political landscape is transformed in 1854 when the Kansas-Nebraska Act makes the expansion of slavery a national issue.A man of considered words and deliberate actions, Lincoln navigates the dynamic politics deftly, taking measured steps, often along a path forged by abolitionists and radicals in his party. Lincoln rises to leadership in the new Republican Party by calibrating his politics to the broadest possible antislavery coalition. As president of a divided nation and commander in chief at war, displaying a similar compound of pragmatism and principle, Lincoln finally embraces what he calls the Civil War's “fundamental and astounding” result: the immediate, uncompensated abolition of slavery and recognition of blacks as American citizens.Foner's Lincoln emerges as a leader, one whose greatness lies in his capacity for moral and political growth through real engagement with allies and critics alike. This powerful work will transform our understanding of the nation's greatest president and the issue that mattered most.

    It is a waste product and a commodity pricier than oil. It can save lives and transmit deadly infections. Each one of us has roughly nine pints of it, yet many don’t even know their own blood type. And for all its ubiquity, the few tablespoons of blood discharged by 800 million women are still regarded as taboo; menstruation is perhaps the single most demonized biological event.Rose George, author of The Big Necessity, is renowned for her intrepid work on topics that are invisible but vitally important. In Nine Pints, she takes us from ancient practices of bloodletting to modern “hemovigilance” teams that track blood-borne diseases. She introduces Janet Vaughan, who set up the world’s first system of mass blood donation during the Blitz, and Arunachalam Muruganantham, known as “Menstrual Man” for his work on sanitary pads for developing countries. She probes the lucrative business of plasma transfusions, in which the U.S. is known as the “OPEC of plasma.” And she looks to the future, as researchers seek to bring synthetic blood to a hospital near you.Spanning science and politics, stories and global epidemics, Nine Pints reveals our life's blood in an entirely new light.

    Though the world at first recoiled at the notion of a woman studying medicine, her intelligence and intensity ultimately won her the acceptance of the male medical establishment. In 1849, she became the first woman in America to receive an M.D. She was soon joined in her iconic achievement by her younger sister, Emily, who was actually the more brilliant physician.Exploring the sisters’ allies, enemies, and enduring partnership, Janice P. Nimura presents a story of trial and triumph. Together, the Blackwells founded the New York Infirmary for Indigent Women and Children, the first hospital staffed entirely by women. Both sisters were tenacious and visionary, but their convictions did not always align with the emergence of women’s rights—or with each other. From Bristol, Paris, and Edinburgh to the rising cities of antebellum America, this richly researched new biography celebrates two complicated pioneers who exploded the limits of possibility for women in medicine. As Elizabeth herself predicted, "a hundred years hence, women will not be what they are now."

    Gordon S. Wood depicts a revolution that was about much more than a break from England, rather it transformed an almost feudal society into a democratic one, whose emerging realities sometimes baffled and disappointed its founding fathers.

    Beloved and hated, venerated and reviled, Andrew Jackson was an orphan who fought his way to the pinnacle of power, bending the nation to his will in the cause of democracy. Jackson's election in 1828 ushered in a new and lasting era in which the people, not distant elites, were the guiding force in American politics. Democracy made its stand in the Jackson years, and he gave voice to the hopes and the fears of a restless, changing nation facing challenging times at home and threats abroad. To tell the saga of Jackson's presidency, acclaimed author Jon Meacham goes inside the Jackson White House. Drawing on newly discovered family letters and papers, he details the human drama-the family, the women, and the inner circle of advisers- that shaped Jackson's private world through years of storm and victory.One of our most significant yet dimly recalled presidents, Jackson was a battle-hardened warrior, the founder of the Democratic Party, and the architect of the presidency as we know it. His story is one of violence, sex, courage, and tragedy. With his powerful persona, his evident bravery, and his mystical connection to the people, Jackson moved the White House from the periphery of government to the center of national action, articulating a vision of change that challenged entrenched interests to heed the popular will- or face his formidable wrath. The greatest of the presidents who have followed Jackson in the White House-from Lincoln to Theodore Roosevelt to FDR to Truman-have found inspiration in his example, and virtue in his vision.Jackson was the most contradictory of men. The architect of the removal of Indians from their native lands, he was warmly sentimental and risked everything to give more power to ordinary citizens. He was, in short, a lot like his country: alternately kind and vicious, brilliant and blind; and a man who fought a lifelong war to keep the republic safe-no matter what it took.