They force us to confront a fundamental biological problem: how can something as large and complex as a human body organize itself from the simplicity of a fertilized egg? A convergence of ideas from embryology, genetics, physics, networks, and control theory has begun to provide real answers. Based on the central principle of 'adaptive self-organization, ' it explains how the interactions of many cells, and of the tiny molecular machines that run them, can organize tissue structures vastly larger than themselves, correcting errors as they go along and creating new layers of complexity where there were none before.Life Unfolding tells the story of human development from egg to adult, from this perspective, showing how our whole understanding of how we come to be has been transformed in recent years. Highlighting how embryological knowledge is being used to understand why bodies age and fail, Jamie A. Daviesexplores the profound and fascinating impacts of our newfound knowledge.

    Mythologized. Controversial.A Harvard evolutionary biologist debunks the myths and cultural stereotypes surrounding testosterone and reveals its far-reaching effects on gender and sexuality, sports, relationships, and many more aspects of our everyday lives.The biological source of virility and masculinity has inspired fascination, investigation, and controversy since antiquity. From the eunuchs in the royal courts of ancient China to the booming market for “elixirs” of youth in nineteenth-century Europe, humans have been obsessed with identifying and manipulating what we now know as testosterone. And the trends show no signs of slowing down—the modern market for testosterone supplements is booming. Thanks to this history and the methods of modern science, today we have a rich body of research about testosterone’s effects in both men and women.The science is clear: testosterone is a major, invisible player in our relationships, sex lives, athletic abilities, childhood play, gender transitions, parenting roles, violent crime, and so much more. But there is still a lot of pushback to the idea that it does, in fact, cause sex differences and significantly influence behavior.Carole Hooven argues in T that acknowledging testosterone as a potent force in society doesn’t reinforce stifling gender norms or patriarchal values. Testosterone and evolution work together to produce a huge variety of human behavior, and that includes a multitude of ways to be masculine or feminine. Understanding the science sheds light on how we work and relate to one another, how we express anger and love, and how we can fight bias and problematic behavior to build a more fair society.

    Teenage girls are taking courses of testosterone and disfiguring their bodies. Parents are undermined; experts are over-relied upon; dissenters in science and medicine are intimidated; free speech truckles under renewed attack; socialized medicine bears hidden consequences; and an intersectional era has arisen in which the desire to escape a dominant identity encourages individuals to take cover in victim groups. Every person who has ever had a skeptical thought about the sudden rush toward a non-binary future but been afraid to express it—this book is for you.

    McCoy, USMCIf you read one book in your lifetime on the warrior culture, this is that book. Active-duty Marine Colonel B. P. McCoy expertly relates his innermost thoughts and feelings, drawing on his mastery of personal leadership. Colonel McCoy understands the intangibles that make up our modern-day warriors, those young Americans on whom we place so much responsibility when we send them into harm's way.The author begins with the institutional design that leads some to believe that because of a manifestation of the American culture in which we're taught to kill from a young age through the use of video games, the task of a warrior would somehow be easily executed, based solely on these inequities. To the contrary, Colonel McCoy points out that the battlefield commander is hampered by the societal digression and the simple fact that young Americans can point a video weapon and kill, never feeling the true effects or suffering associated with actual combat. He explains that our culture is not that of predator, but more of prey. Through examples, he concludes that the American society places grave consequence on the taking of a human life, while we still require our young to bear arms against our enemies and to extinguish life. Only through superb training, conducted by passionate leaders, do our young Americans become moral warriors.Colonel McCoy describes the total cost of combat and the price paid by all who choose to become warriors. By pointing to positive training examples and keying on the effects of situational training—battle drills—conducted prior to and during combat, he successfully trained his Marines and developed the proper habits that would be the difference between life and death during combat. He directed his Marines to become "experts in the application of violence," without sacrificing their humanity. In the book, it became clear that he found the combination that allowed his men to achieve tactical superiority in every aspect.The essence of war is violence and the act of killing legitimate human targets without hesitation. To accomplish this, he instituted meaningful training and used his refined principles as a human being to guide him in the leadership and administration on the moral code that rules the field of battle. He is the perfect example of all that we hold dear in our warrior culture. He loved his men, showed them the right way through his personal example, guided his actions with passion and relayed his feelings to his men completely. He is quick to note his own shortcomings and how he overcame them and was the inspiration to the team that triumphed when all Marines survived the day.Emotionally riveting, The Passion of Command provides inside information into the warrior culture and allows one to grasp the complexities when hardening the mind, body, and spirit for the rigors of combat. Most find it difficult to communicate the human effects of combat to people who have never experienced the harsh realities associated with actually engaging an enemy. Colonel McCoy doesn't have that problem. He has opened the door and let the reader in

    In The Viral Storm, award-winning biologist Nathan Wolfe tells the story of how viruses and human beings have evolved side by side through history; how deadly viruses like HIV, swine flu, and bird flu almost wiped us out in the past; and why modern life has made our species vulnerable to the threat of a global pandemic.Wolfe's research missions to the jungles of Africa and the rain forests of Borneo have earned him the nickname "the Indiana Jones of virus hunters," and here Wolfe takes readers along on his groundbreaking and often dangerous research trips—to reveal the surprising origins of the most deadly diseases and to explain the role that viruses have played in human evolution.In a world where each new outbreak seems worse than the one before, Wolfe points the way forward, as new technologies are brought to bear in the most remote areas of the world to neutralize these viruses and even harness their power for the good of humanity. His provocative vision of the future will change the way we think about viruses, and perhaps remove a potential threat to humanity's survival.

    This Harriman House edition includes Charles Mackay's account of the three infamous financial manias - John Law's Mississipi Scheme, the South Sea Bubble, and Tulipomania.Between the three of them, these historic episodes confirm that greed and fear have always been the driving forces of financial markets, and, furthermore, that being sensible and clever is no defence against the mesmeric allure of a popular craze with the wind behind it.In writing the history of the great financial manias, Charles Mackay proved himself a master chronicler of social as well as financial history. Blessed with a cast of characters that covered all the vices, gifted a passage of events which was inevitably heading for disaster, and with the benefit of hindsight, he produced a record that is at once a riveting thriller and absorbing historical document. A century and a half later, it is as vibrant and lurid as the day it was written.For modern-day investors, still reeling from the dotcom crash, the moral of the popular manias scarcely needs spelling out. When the next stock market bubble comes along, as it surely will, you are advised to recall the plight of some of the unfortunates on these pages, and avoid getting dragged under the wheels of the careering bandwagon yourself.

    Our intellectual capacity, our introversion or extraversion, our vulnerability to mental illness, even whether we are a morning person - all of these aspects of our personality are profoundly shaped by our inherited DNA differences.In Blueprint, Robert Plomin, a pioneer in the field of behavioural genetics, draws on a lifetime's worth of research to make the case that DNA is the most important factor shaping who we are. Our families, schools and the environment around us are important, but they are not as influential as our genes. This is why, he argues, teachers and parents should accept children for who they are, rather than trying to mould them in certain directions. Even the environments we choose and the signal events that impact our lives, from divorce to addiction, are influenced by our genetic predispositions. Now, thanks to the DNA revolution, it is becoming possible to predict who we will become, at birth, from our DNA alone. As Plomin shows us, these developments have sweeping implications for how we think about parenting, education, and social mobility.A game-changing book by a leader in the field, Blueprint shows how the DNA present in the single cell with which we all begin our lives can impact our behaviour as adults.

    Focusing especially on Christianity but including Judaism, Islam, Buddhism, Hinduism, and Chinese spiritualities, Armstrong examines the diminished impulse toward religion in our own time, when a significant number of people either want nothing to do with God or question the efficacy of faith. Why has God become unbelievable? Why is it that atheists and theists alike now think and speak about God in a way that veers so profoundly from the thinking of our ancestors?Answering these questions with the same depth of knowledge and profound insight that have marked all her acclaimed books, Armstrong makes clear how the changing face of the world has necessarily changed the importance of religion at both the societal and the individual level. And she makes a powerful, convincing argument for drawing on the insights of the past in order to build a faith that speaks to the needs of our dangerously polarized age. Yet she cautions us that religion was never supposed to provide answers that lie within the competence of human reason; that, she says, is the role of logos. The task of religion is “to help us live creatively, peacefully, and even joyously with realities for which there are no easy explanations.” She emphasizes, too, that religion will not work automatically. It is, she says, a practical discipline: its insights are derived not from abstract speculation but from “dedicated intellectual endeavor” and a “compassionate lifestyle that enables us to break out of the prism of selfhood.”

    From such twenty-first-century forces, we have seen declines in previous global health gains, with sharp increases in vaccine-preventable and neglected diseases on the Arabian Peninsula, in Venezuela, in parts of Africa, and even on the Gulf Coast of the United States. In Preventing the Next Pandemic, international vaccine scientist and tropical disease and coronavirus expert Peter J. Hotez, MD, PhD, argues that we can--and must--rely on vaccine diplomacy to address this new world order in disease and global health. Detailing his years in the lab developing new vaccines, Hotez also recounts his travels around the world to shape vaccine partnerships with people in countries both rich and poor in an attempt to head off major health problems. Building on the legacy of Dr. Albert Sabin, who developed the oral polio vaccine with Soviet scientists at the height of the Cold War, he explains how he is still working to refresh and redirect vaccine diplomacy toward neglected and newly emerging diseases.Hotez reveals how--during his Obama-era tenure as the US Science Envoy for the Middle East and North Africa, which coincided with both the rise in these geopolitical forces and climate change--he witnessed tropical infectious diseases and established vaccine partnerships that may still combat them up close. He explores why, since 2015, we've seen the decline of global cooperation and cohesion, to the detriment of those programs that are meant to benefit the most vulnerable people in the world. Unfortunately, Hotez asserts, these negative global events kick off a never-ending loop. Problems in a country may lead to disease outbreaks, but those outbreaks can lead to further problems--such as the impact of coronavirus on China's society and economy, which has been felt around the globe. Zeroing in on the sociopolitical and environmental factors that drive our most controversial and pressing global health concerns, Hotez proposes historically proven methods to soothe fraught international relations while preparing us for a safer, healthier future. He hammers home the importance of public engagement to communicate the urgency of embracing science during troubled times.Touching on a range of disease, from leishmaniasis, schistosomiasis, and Middle East Respiratory Syndrome (MERS) to COVID-19, Preventing the Next Pandemic has always been a timely goal, but it will be even more important in a COVID and post-COVID world.

    Here is the ultimate guide to over 450 of the most significant intellectual terms, movements, and religions that help shape the society we live in. Simply, concisely, and with personality, ‘Isms and ‘Ologies clarifies buzz terms like jihad, often defined as “holy war” but which literally means “striving” ;and illustrates the differences between Conservatism, Paleoconservatism, and Neoconservatism. It explains String Theory (which attempts to unify Quantum Mechanics and Einsteinian Relativity); describes Fauvism (an artistic movement that paved the way for Expressionism and Cubism); defines Locofocoism (an American political ideology named after a “self-lighting cigar)”; and identifies and explores so much more. Helpfully divided into categories–including politics, history, philosophy and the arts, economics, religion, science, and medicine–cross referenced, and thoroughly indexed, ‘Isms and ‘Ologies is a must have for the budding intellectual in everyone.

    Bernard Haisch contends that there is a purpose and an underlying intelligence behind the Universe, one that is consistent with modern science, especially the Big Bang and evolution. It is based on recent discoveries that there are numerous coincidences and fine-tunings of the laws of nature that seem extraordinarily unlikely.A more rational concept of God is called for. As astrophysicist Sir James Jeans wrote, "the Universe begins to look more like a great thought than like a great machine."Despite bestsellers by Christopher Hitchens, Richard Dawkins, and Sam Harris that have denounced the evils of religion and proclaimed that science has shown that there is no God, The Purpose-Guided Universe shows how one can believe in God and science.

    A brief, but insightful look at history shows the evolution of combat, the development of the physical and psychological leverage that enables humans to kill other humans, followed by an objective examination of domestic violence in America. The authors reveal the nature of the warrior, brave men and women who train their minds and bodies to go to that place from which others flee. After examining the incredible impact of a few true warriors in battle, On Combat presents new and exciting research as to how to train the mind to become inoculated to stress, fear and even pain.

    Moreover, present-day research on electricity and ion channels has created one of the most exciting fields in science, shedding light on conditions ranging from diabetes and allergies to cystic fibrosis, migraines, and male infertility. With inimitable wit and a clear, fresh voice, award-winning researcher Frances Ashcroft weaves together compelling real-life stories with the latest scientific findings, giving us a spectacular account of the body electric.

    Yet despite its influence on the 20th century, there are no modern histories of the trial and its aftermath. This book fills that void not only by skillfully narrating the trial's events, but also by framing it in a broader social context, showing how its influence has cut across religious, cultural, educational and political lines. With new material from both the prosecution and the defense, along with the author's astute historical and legal analysis, "Summer for the Gods" is destined to become a new classic about a pivotal milestone in American history.

    The Age of Reason represents the results of years of study and reflection by Thomas Paine on the place of religion in society.Paine wrote: "Of all the tyrannies that affect mankind, tyranny in religion is the worst; every other species of tyranny is limited to the world we live in; but this attempts to stride beyond the grave, and seeks to pursue us into eternity."The cool rationale of Paine's The Age of Reason influenced religious thinking throughout the world; and its pervasieve influence continues to the present day.