Ten Drugs: How Plants, Powders, and Pills Have Shaped the History of Medicine


Thomas Hager - 2019
    It could be an oddball researcher’s genius insight, a catalyzing moment in geopolitical history, a new breakthrough technology, or an unexpected but welcome side effect discovered during clinical trials. Piece together these stories, as Thomas Hager does in this remarkable, century-spanning history, and you can trace the evolution of our culture and the practice of medicine.  ​Beginning with opium, the “joy plant,” which has been used for 10,000 years, Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.

The Wild Life of Our Bodies: Predators, Parasites, and Partners That Shape Who We Are Today


Rob Dunn - 2011
    Dunn illuminates the nuanced, often imperceptible relationships that exist between homo sapiens and other species, relationships that underpin humanity’s ability to thrive and prosper in every circumstance.

The Social Conquest of Earth


Edward O. Wilson - 2012
    Refashioning the story of human evolution in a work that is certain to generate headlines, Wilson draws on his remarkable knowledge of biology and social behavior to show that group selection, not kin selection, is the primary driving force of human evolution. He proves that history makes no sense without prehistory, and prehistory makes no sense without biology. Demonstrating that the sources of morality, religion, and the creative arts are fundamentally biological in nature, Wilson presents us with the clearest explanation ever produced as to the origin of the human condition and why it resulted in our domination of the Earth’s biosphere.

Fossil Men: The Quest for the Oldest Skeleton and the Origins of Humankind


Kermit Pattison - 2020
    Radiometric dating of nearby rocks indicated the skeleton, classified as Ardipithecus ramidus, was 4.4 million years old, more than a million years older than "Lucy," then the oldest known human ancestor. The findings challenged many assumptions about human evolution--how we started walking upright, how we evolved our nimble hands, and, most significantly, whether we were descended from an ancestor that resembled today's chimpanzee--and repudiated a half-century of paleoanthropological orthodoxy.Fossil Men is the first full-length exploration of Ardi, the fossil men who found her, and her impact on what we know about the origins of the human species. It is a scientific detective story played out in anatomy and the natural history of the human body. Kermit Pattison brings into focus a cast of eccentric, obsessive scientists, including one of the world's greatest fossil hunters, Tim White--an exacting and unforgiving fossil hunter whose virtuoso skills in the field were matched only by his propensity for making enemies; Gen Suwa, a Japanese savant who sometimes didn't bother going home at night to devote more hours to science; Owen Lovejoy, a onetime creationist-turned-paleoanthropologist; Berhane Asfaw, who survived imprisonment and torture to become Ethiopia's most senior paleoanthropologist and who fought for African scientists to gain equal footing in the study of human origins; and the Leakeys, for decades the most famous family in paloanthropology.An intriguing tale of scientific discovery, obsession and rivalry that moves from the sun-baked desert of Africa and a nation caught in a brutal civil war, to modern high-tech labs and academic lecture halls, Fossil Men is popular science at its best, and a must read for fans of Jared Diamond, Richard Dawkins, and Edward O. Wilson.

Death by Black Hole: And Other Cosmic Quandaries


Neil deGrasse Tyson - 2006
    "One of today's best popularizers of science." —Kirkus Reviews.Loyal readers of the monthly "Universe" essays in Natural History magazine have long recognized Neil deGrasse Tyson's talent for guiding them through the mysteries of the cosmos with stunning clarity and almost childlike enthusiasm. Here, Tyson compiles his favorite essays across a myriad of cosmic topics. The title essay introduces readers to the physics of black holes by explaining the gory details of what would happen to your body if you fell into one. "Holy Wars" examines the needless friction between science and religion in the context of historical conflicts. "The Search for Life in the Universe" explores astral life from the frontiers of astrobiology. And "Hollywood Nights" assails the movie industry's feeble efforts to get its night skies right. Known for his ability to blend content, accessibility, and humor, Tyson is a natural teacher who simplifies some of the most complex concepts in astrophysics while simultaneously sharing his infectious excitement about our universe.

Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients


Ben Goldacre - 2012
    We like to imagine that it’s based on evidence and the results of fair tests. In reality, those tests are often profoundly flawed. We like to imagine that doctors are familiar with the research literature surrounding a drug, when in reality much of the research is hidden from them by drug companies. We like to imagine that doctors are impartially educated, when in reality much of their education is funded by industry. We like to imagine that regulators let only effective drugs onto the market, when in reality they approve hopeless drugs, with data on side effects casually withheld from doctors and patients.All these problems have been protected from public scrutiny because they’re too complex to capture in a sound bite. But Dr. Ben Goldacre shows that the true scale of this murderous disaster fully reveals itself only when the details are untangled. He believes we should all be able to understand precisely how data manipulation works and how research misconduct on a global scale affects us. In his own words, “the tricks and distortions documented in these pages are beautiful, intricate, and fascinating in their details.” With Goldacre’s characteristic flair and a forensic attention to detail, Bad Pharma reveals a shockingly broken system and calls for something to be done. This is the pharmaceutical industry as it has never been seen before.

Woman: An Intimate Geography


Natalie Angier - 1999
    Angier takes readers on a mesmerizing tour of female anatomy and physiology that explores everything from organs to orgasm, and delves into topics such as exercise, menopause, and the mysterious properties of breast milk.A self-proclaimed "scientific fantasia of womanhood." Woman ultimately challenges widely accepted Darwinian-based gender stereotypes. Angier shows how cultural biases have influenced research in evolutionary psychology (the study of the biological bases of behavior) and consequently led to dubious conclusions about "female nature." such as the idea that women are innately monogamous while men are natural philanderers.But Angier doesn't just point fingers; she offers optimistic alternatives and transcends feminist polemics with an enlightened subversiveness that makes for a joyful, fresh vision of womanhood. Woman is a seminal work that will endure as an essential read for anyone intersted in how biology affects who we are as women, as men, and as human beings.

Pandora's Seed: The Unforeseen Cost of Civilization


Spencer Wells - 2010
    Using the latest genetic and anthropological data, Spencer Wells demonstrates that although humankind's decision to control our own food supply is what propelled us into the modern world, it had many downsides that we're just now beginning to recognize.

The Upright Thinkers: The Human Journey from Living in Trees to Understanding the Cosmos


Leonard Mlodinow - 2015
      Leonard Mlodinow takes us on a passionate and inspiring tour through the exciting history of human progress and the key events in the development of science. In the process, he presents a fascinating new look at the unique characteristics of our species and our society that helped propel us from stone tools to written language and through the birth of chemistry, biology, and modern physics to today’s technological world.   Along the way he explores the cultural conditions that influenced scientific thought through the ages and the colorful personalities of some of the great philosophers, scientists, and thinkers: Galileo, who preferred painting and poetry to medicine and dropped out of university; Isaac Newton, who stuck needlelike bodkins into his eyes to better understand changes in light and color; and Antoine Lavoisier, who drank nothing but milk for two weeks to examine its effects on his body. Charles Darwin, Albert Einstein, Werner Heisenberg, and many lesser-known but equally brilliant minds also populate these pages, each of their stories showing how much of human achievement can be attributed to the stubborn pursuit of simple questions (why? how?), bravely asked.  The Upright Thinkers is a book for science lovers and for anyone interested in creative thinking and in our ongoing quest to understand our world. At once deeply informed, accessible, and infused with the author’s trademark wit, this insightful work is a stunning tribute to humanity’s intellectual curiosity.  (With black-and-white illustrations throughout.)

The Rise and Fall of the Dinosaurs: A New History of a Lost World


Stephen Brusatte - 2018
    Sixty-six million years ago, the Earth’s most fearsome creatures vanished. Today they remain one of our planet’s great mysteries. Now The Rise and Fall of the Dinosaurs reveals their extraordinary, 200-million-year-long story as never before.In this captivating narrative (enlivened with more than seventy original illustrations and photographs), Steve Brusatte, a young American paleontologist who has emerged as one of the foremost stars of the field—naming fifteen new species and leading groundbreaking scientific studies and fieldwork—masterfully tells the complete, surprising, and new history of the dinosaurs, drawing on cutting-edge science to dramatically bring to life their lost world and illuminate their enigmatic origins, spectacular flourishing, astonishing diversity, cataclysmic extinction, and startling living legacy. Captivating and revelatory, The Rise and Fall of the Dinosaurs is a book for the ages.Brusatte traces the evolution of dinosaurs from their inauspicious start as small shadow dwellers—themselves the beneficiaries of a mass extinction caused by volcanic eruptions at the beginning of the Triassic period—into the dominant array of species every wide-eyed child memorizes today, T. rex, Triceratops, Brontosaurus, and more. This gifted scientist and writer re-creates the dinosaurs’ peak during the Jurassic and Cretaceous, when thousands of species thrived, and winged and feathered dinosaurs, the prehistoric ancestors of modern birds, emerged. The story continues to the end of the Cretaceous period, when a giant asteroid or comet struck the planet and nearly every dinosaur species (but not all) died out, in the most extraordinary extinction event in earth’s history, one full of lessons for today as we confront a “sixth extinction.”Brusatte also recalls compelling stories from his globe-trotting expeditions during one of the most exciting eras in dinosaur research—which he calls “a new golden age of discovery”—and offers thrilling accounts of some of the remarkable findings he and his colleagues have made, including primitive human-sized tyrannosaurs; monstrous carnivores even larger than T. rex; and paradigm-shifting feathered raptors from China.An electrifying scientific history that unearths the dinosaurs’ epic saga, The Rise and Fall of the Dinosaurs will be a definitive and treasured account for decades to come.

Darwin's Dangerous Idea: Evolution and the Meanings of Life


Daniel C. Dennett - 1995
    Dennett, whom Chet Raymo of The Boston Globe calls "one of the most provocative thinkers on the planet," focuses his unerringly logical mind on the theory of natural selection, showing how Darwin's great idea transforms and illuminates our traditional view of humanity's place in the universe. Dennett vividly describes the theory itself and then extends Darwin's vision with impeccable arguments to their often surprising conclusions, challenging the views of some of the most famous scientists of our day.

10% Human: How Your Body's Microbes Hold the Key to Health and Happiness


Alanna Collen - 2015
    For every one of the cells that make up the vessel that you call your body, there are nine impostor cells hitching a ride. You are not just flesh and blood, muscle and bone, brain and skin, but also bacteria and fungi. Over your lifetime, you will carry the equivalent weight of five African elephants in microbes. You are not an individual but a colony.Until recently, we had thought our microbes hardly mattered, but science is revealing a different story, one in which microbes run our bodies and becoming a healthy human is impossible without them.In this riveting, shocking, and beautifully written book, biologist Alanna Collen draws on the latest scientific research to show how our personal colony of microbes influences our weight, our immune system, our mental health, and even our choice of partner. She argues that so many of our modern diseases—obesity, autism, mental illness, digestive disorders, allergies, autoimmunity afflictions, and even cancer—have their root in our failure to cherish our most fundamental and enduring relationship: that with our personal colony of microbes.Many of the questions about modern diseases left unanswered by the Human Genome Project are illuminated by this new science. And the good news is that unlike our human cells, we can change our microbes for the better. Collen's book is a revelatory and indispensable guide. It is science writing at its most relevant: life—and your body—will never seem the same again.

The Panic Virus: A True Story of Medicine, Science, and Fear


Seth Mnookin - 2011
    The media seized hold of the story and, in the process, helped to launch one of the most devastating health scares ever. In the years to come Wakefield would be revealed as a profiteer in league with class-action lawyers, and he would eventually lose his medical license. Meanwhile, one study after another failed to find any link between childhood vaccines and autism. Yet the myth that vaccines somehow cause developmental disorders lives on. Despite the lack of corroborating evidence, it has been popularized by media personalities such as Oprah Winfrey and Jenny McCarthy and legitimized by journalists who claim that they are just being fair to “both sides” of an issue about which there is little debate. Meanwhile, millions of dollars have been diverted from potential breakthroughs in autism research; families have spent their savings on ineffective “miracle cures"; and declining vaccination rates have led to outbreaks of deadly illnesses like Hib, measles, and whooping cough. Most tragic of all is the increasing number of children dying from vaccine-preventable diseases. In The Panic Virus Seth Mnookin draws on interviews with parents, public-health advocates, scientists, and anti-vaccine activists to tackle a fundamental question: How do we decide what the truth is? The fascinating answer helps explain everything from the persistence of conspiracy theories about 9/11 to the appeal of talk-show hosts who demand that President Obama “prove” he was born in America. The Panic Virus is the ultimate cautionary tale for our time.

The Telomere Effect: A Revolutionary Approach to Living Younger, Healthier, Longer


Elizabeth Blackburn - 2017
    Elizabeth Blackburn discovered a biological indicator called telomerase, the enzyme that replenishes telomeres, which protect our genetic heritage. Dr. Blackburn and Dr. Elissa Epel's research shows that the length and health of one's telomeres are a biological underpinning of the long-hypothesized mind-body connection. They and other scientists have found that changes we can make to our daily habits can protect our telomeres and increase our health spans (the number of years we remain healthy, active, and disease-free).THE TELOMERE EFFECT reveals how Blackburn and Epel's findings, together with research from colleagues around the world, cumulatively show that sleep quality, exercise, aspects of diet, and even certain chemicals profoundly affect our telomeres, and that chronic stress, negative thoughts, strained relationships, and even the wrong neighborhoods can eat away at them. Drawing from this scientific body of knowledge, they share lists of foods and suggest amounts and types of exercise that are healthy for our telomeres, mind tricks you can use to protect yourself from stress, and information about how to protect your children against developing shorter telomeres, from pregnancy through adolescence. And they describe how we can improve our health spans at the community level, with neighborhoods characterized by trust, green spaces, and safe streets. THE TELOMERE EFFECT will make you reassess how you live your life on a day-to-day basis. It is the first book to explain how we age at a cellular level and how we can make simple changes to keep our chromosomes and cells healthy, allowing us to stay disease-free longer and live more vital and meaningful lives.

On Immunity: An Inoculation


Eula Biss - 2014
    She finds that you cannot immunize your child, or yourself, from the world.In this bold, fascinating book, Biss investigates the metaphors and myths surrounding our conception of immunity and its implications for the individual and the social body. As she hears more and more fears about vaccines, Biss researches what they mean for her own child, her immediate community, America, and the world, both historically and in the present moment. She extends a conversation with other mothers to meditations on Voltaire's Candide, Bram Stoker's Dracula, Rachel Carson's Silent Spring, Susan Sontag's AIDS and Its Metaphors, and beyond.On Immunity is a moving account of how we are all interconnected-our bodies and our fates.