Focusing on two romances - Jessica's dizzying infatuation with a hugely successful young heroin dealer, Boy George, and Coco's first love with Jessica's little brother, Cesar - Random Family is the story of young people trying to outrun their destinies. Jessica and Boy George ride the wild adventure between riches and ruin, while Coco and Cesar stick closer to the street, all four caught in a precarious dance between survival and death. Friends get murdered; the DEA and FBI investigate Boy George; Cesar becomes a fugitive; Jessica and Coco endure homelessness, betrayal, the heartbreaking separation of prison, and, throughout it all, the insidious damage of poverty.Charting the tumultuous cycle of the generations - as girls become mothers, boys become criminals, and hope struggles against deprivation - LeBlanc slips behind the cold statistics and sensationalism and comes back with a riveting, haunting, and true story.

    We take for granted that we can remember, feel emotion, navigate, empathize, and understand the world around us, but how would our lives change if these abilities were dramatically enhanced--or disappeared overnight?Helen Thomson has spent years traveling the world, tracking down incredibly rare brain disorders. In Unthinkable she tells the stories of nine extraordinary people she encountered along the way. From the man who thinks he's a tiger to the doctor who feels the pain of others just by looking at them to a woman who hears music that’s not there, their experiences illustrate how the brain can shape our lives in unexpected and, in some cases, brilliant and alarming ways.Story by remarkable story, Unthinkable takes us on an unforgettable journey through the human brain. Discover how to forge memories that never disappear, how to grow an alien limb, and how to make better decisions. Learn how to hallucinate and how to make yourself happier in a split second. Find out how to avoid getting lost, how to see more of your reality, even how exactly you can confirm you are alive. Think the unthinkable.

    She draws from her own experiences of illness and bodily injury to engage in an exploration that extends far beyond her life, spanning wide-ranging territory—from poverty tourism to phantom diseases, street violence to reality television, illness to incarceration—in its search for a kind of sight shaped by humility and grace.

    Nobel Prize winner Kandel intertwines cogntive psychology, neuroscience, and molecular biology with his own quest to understand memory.

    Veterans and their families deal with the painful aftermath of combat; one in five Americans has been molested; one in four grew up with alcoholics; one in three couples have engaged in physical violence. Such experiences inevitably leave traces on minds, emotions, and even on biology. Sadly, trauma sufferers frequently pass on their stress to their partners and children. Renowned trauma expert Bessel van der Kolk has spent over three decades working with survivors. In The Body Keeps the Score, he transforms our understanding of traumatic stress, revealing how it literally rearranges the brain’s wiring—specifically areas dedicated to pleasure, engagement, control, and trust. He shows how these areas can be reactivated through innovative treatments including neurofeedback, mindfulness techniques, play, yoga, and other therapies. Based on Dr. van der Kolk’s own research and that of other leading specialists, The Body Keeps the Score offers proven alternatives to drugs and talk therapy—and a way to reclaim lives.

    An experienced therapist offers groundbreaking and compassionate techniques for helping chronically inflexible children, who suffer from excessively immoderate tempers, showing how brain-based deficits contribute to these problems and offering positive and constructive ways to calm things down.

    Vincent DiMaio and veteran crime writer Ron Franscell guide us behind the morgue doors to tell a fascinating life story through the cases that have made Di Maio famous-from the exhumation of assassin Lee Harvey Oswald to the complex issues in the shooting of Florida teenager Trayvon Martin.Beginning with his street-smart Italian origins in Brooklyn, the book spans 40 years of work and more than 9,000 autopsies, and Di Maio's eventual rise into the pantheon of forensic scientists. One of the country's most methodical and intuitive criminal pathologists will dissect himself, maintaining a nearly continuous flow of suspenseful stories, revealing anecdotes, and enough macabre insider details to rivet the most fervent crime fans.

    And yet, the 1949 discovery of lithium as a cure for bipolar disorder is perhaps one of the most important—yet largely unsung—breakthroughs of the modern era. In Lithium, Walter Brown, a practicing psychiatrist and professor at Brown, reveals two unlikely success stories: that of John Cade, the physician whose discovery would come to save an untold number of lives and launch a pharmacological revolution, and that of a miraculous metal rescued from decades of stigmatization.From insulin comas and lobotomy to incarceration to exile, Brown chronicles the troubling history of the diagnosis and (often ineffective) treatment of bipolar disorder through the centuries, before the publication of a groundbreaking research paper in 1949. Cade’s “Lithium Salts in the Treatment of Psychotic Excitement” described, for the first time, lithium’s astonishing efficacy at both treating and preventing the recurrence of manic-depressive episodes, and would eventually transform the lives of patients, pharmaceutical researchers, and practicing physicians worldwide. And yet, as Brown shows, it would be decades before lithium would overcome widespread stigmatization as a dangerous substance, and the resistance from the pharmaceutical industry, which had little incentive to promote a naturally occurring drug that could not be patented.With a vivid portrait of the story’s unlikely hero, John Cade, Brown also describes a devoted naturalist who, unlike many modern medical researchers, did not benefit from prestigious research training or big funding sources (Cade’s “laboratory” was the unused pantry of an isolated mental hospital). As Brown shows, however, these humble conditions were the secret to his historic success: Cade was free to follow his own restless curiosity, rather than answer to an external funding source. As Lithium makes tragically clear, medical research—at least in America—has transformed in such a way that serendipitous discoveries like Cade’s are unlikely to occur ever again.Recently described by the New York Times as the “Cinderella” of psychiatric drugs, lithium has saved countless of lives and billions of dollars in healthcare costs. In this revelatory biography of a drug and the man who fought for its discovery, Brown crafts a captivating picture of modern medical history—revealing just how close we came to passing over this extraordinary cure.

    For most of that time, she didn't know why. All of her trips to the ER and her daily anguish, pain, and lethargy only ever resulted in one question: How could any one person be this sick? Several drug addictions, three major hospitalizations, and over $100,000 later, she finally had a diagnosis: late-stage Lyme disease. Sick is Khakpour's arduous, emotional journey—as a woman, a writer, and a lifelong sufferer of undiagnosed health problems—through the chronic illness that perpetually left her a victim of anxiety, living a life stymied by an unknown condition.Divided by settings, Khakpour guides the reader through her illness by way of the locations that changed her course—New York, LA, New Mexico, and Germany—as she meditates on both the physical and psychological impacts of uncertainty, and the eventual challenge of accepting the diagnosis she had searched for over the course of her adult life. With candor and grace, she examines her subsequent struggles with mental illness, her addiction to the benzodiazepines prescribed by her psychiatrists, and her ever-deteriorating physical health. A story about survival, pain, and transformation, Sick is a candid, illuminating narrative of hope and uncertainty, boldly examining the deep impact of illness on one woman's life.

    She recounts the travails of growing up in a large, affluent family where there was a paucity of love and of basics such as food and clothing despite the presence of a chauffeur and a cook. She goes on to recount her early hospitalization for depression in poignant detail, as well as her complex relationship with her mercurial, withholding mother.Along the way Merkin also discusses her early, redemptive love of reading and gradual emergence as a writer. She eventually marries, has a child, and suffers severe postpartum depression, for which she is again hospitalized. Merkin also discusses her visits to various therapists and psychopharmocologists, which enables her to probe the causes of depression and its various treatments. The book ends in the present, where the writer has learned how to navigate her depression, if not “cure” it, after a third hospitalization in the wake of her mother’s death.

    Recounts stories from her vast case files that are alternately terrifying, tragically comic, and profoundly moving, all while she deals with her best friend and fellow doctor's fight with cancer.

    their doctors."It was the dog who found me."Such is the stark confession launching the harrowing scene that begins The Asylum for Wayward Victorian Girls as Emilie Autumn, a young musician on the verge of a bright career, attempts suicide by overdosing on the antipsychotics prescribed to treat her bipolar disorder. Upon being discovered, Emilie is revived and immediately incarcerated in a maximum-security psych ward, despite her protestations that she is not crazy, and can provide valid reasons for her actions if someone would only listen.Treated as a criminal, heavily medicated, and stripped of all freedoms, Emilie is denied communication with the outside world, and falls prey to the unwelcome attentions of Dr. Sharp, head of the hospital's psychiatry department. As Dr. Sharp grows more predatory by the day, Emilie begins a secret diary to document her terrifying experience, and to maintain her sanity in this environment that could surely drive anyone mad. But when Emilie opens her notebook to find a desperate letter from a young woman imprisoned within an insane asylum in Victorian England, and bearing her own name and description, a portal to another world is blasted wide open.As these letters from the past continue to appear, Emilie escapes further into this mysterious alternate reality where sisterhoods are formed, romance between female inmates blossoms, striped wallpaper writhes with ghosts, and highly intellectual rats speak the Queen's English.But is it real? Or is Emilie truly as mad as she is constantly told she is?The Asylum for Wayward Victorian Girls blurs harsh reality and magical historical fantasy whilst issuing a scathing critique of society's treatment of women and the mental health care industry's treatment of its patients, showing in the process that little has changed throughout the ages.Welcome to the Asylum. Are you committed?

    From the United States Memory Championship to deep within the author's own mind, this is an electrifying work of journalism that reminds us that, in every way that matters, we are the sum of our memories.

    Parents and family members who never thought they could get inside the head of their autistic loved one, at last, have a way to break through to the curious, subtle, and complex life within.Using an alphabet grid to painstakingly construct words, sentences, and thoughts that he is unable to speak out loud, Naoki answers even the most delicate questions that people want to know. Questions such as: “Why do people with autism talk so loudly and weirdly?” “Why do you line up your toy cars and blocks?” “Why don’t you make eye contact when you’re talking?” and “What’s the reason you jump?” (Naoki’s answer: “When I’m jumping, it’s as if my feelings are going upward to the sky.”) With disarming honesty and a generous heart, Naoki shares his unique point of view on not only autism but life itself. His insights—into the mystery of words, the wonders of laughter, and the elusiveness of memory—are so startling, so strange, and so powerful that you will never look at the world the same way again.

    During that year of physical recovery, Runyon began to question what he’d done, undertaking the complicated journey from near-death back to high school, and from suicide back to the emotional mainstream of life.In the tradition of Running with Scissors and Girl, Interrupted, The Burn Journals is a truly remarkable book about teenage despair and recovery.