A fun and fascinating look at great scientific paradoxes.   Throughout history, scientists have come up with theories and ideas that just don't seem to make sense.  These we call paradoxes.  The paradoxes Al-Khalili offers are drawn chiefly from physics and astronomy and represent those that have stumped some of the finest minds.  For example, how can a cat be both dead and alive at the same time?  Why will Achilles never beat a tortoise in a race, no matter how fast he runs?  And how can a person be ten years older than his twin?   With elegant explanations that bring the reader inside the mind of those who've developed them, Al-Khalili helps us to see that, in fact, paradoxes can be solved if seen from the right angle.  Just as surely as Al-Khalili narrates the enduring fascination of these classic paradoxes, he reveals their underlying logic.  In doing so, he brings to life a select group of the most exciting concepts in human knowledge.  Paradox is mind-expanding fun.

    Now he stands ready to revolutionize both neuroscience and computing in one stroke, with a new understanding of intelligence itself.Hawkins develops a powerful theory of how the human brain works, explaining why computers are not intelligent and how, based on this new theory, we can finally build intelligent machines.The brain is not a computer, but a memory system that stores experiences in a way that reflects the true structure of the world, remembering sequences of events and their nested relationships and making predictions based on those memories. It is this memory-prediction system that forms the basis of intelligence, perception, creativity, and even consciousness.In an engaging style that will captivate audiences from the merely curious to the professional scientist, Hawkins shows how a clear understanding of how the brain works will make it possible for us to build intelligent machines, in silicon, that will exceed our human ability in surprising ways.Written with acclaimed science writer Sandra Blakeslee, On Intelligence promises to completely transfigure the possibilities of the technology age. It is a landmark book in its scope and clarity.

    What happened, how it happened, and what it means to you today. A colorful cast of characters whose discoveries were often driven not only by personal tragedy, curiosity, and hard work, but petty bickering, dumb luck, and a healthy dose of humor. For anyone interested in science, medicine, and beyond... Why are you alive right now? Chances are, you owe your life to one of the remarkable medical discoveries in this book. Maybe it was vaccines. Or antibiotics. Or X-rays. Revolutionary medical breakthroughs like these haven’t just changed the way we treat disease, they’ve transformed how we understand ourselves and the world we live in. In Breakthrough!, Jon Queijo tells the hidden stories behind 10 of history’s most amazing medical discoveries. This isn’t dry history: These are life-and-death mysteries uncovered, tales of passionate, often-mocked individuals who stood their ground and were proven right. From germs to genetics, the ancient Hippocrates to the cutting edge, these are stories that have changed the world—and, quite likely, saved your life.

    Brenda Maddox tells a powerful story of a remarkably single-minded, forthright, and tempestuous young woman who, at the age of fifteen, decided she was going to be a scientist, but who was airbrushed out of the greatest scientific discovery of the twentieth century.

    Scientists have long supported this assumption by claiming that emotions are hardwired in the body or the brain. Today, however, the science of emotion is in the midst of a revolution on par with the discovery of relativity in physics and natural selection in biology—ans this paradigm shift has far-reaching implications for us all.Leading the charge is psychologist and neuroscientist Lisa Feldman Barrett, whose theory of emotion is driving a deeper understanding of the mind and brain, and shedding new light on what it means to be human. Her research overturns the widely held belief that emotions are housed in different parts of the brain and are universally expressed and recognized. Instead, she has shown that emotion is constructed in the moment, by core systems that interact across the whole brain, aided by a lifetime of learning. This new theory means that you play a much greater role in your emotional life than you ever thought. Its repercussions are already shaking the foundations not only of psychology but also of medicine, the legal system, child-rearing, meditation, and even airport security.Why do emotions feel automatic? Does rational thought really control emotion? How does emotion affect disease? How can you make your children more emotionally intelligent? How Emotions Are Made answers these questions and many more, revealing the latest research and intriguing practical applications of the new science of emotion, mind, and brain.

    On the eve of this centenary, journalist Johann Hari set off on an epic three-year, thirty-thousand-mile journey into the war on drugs. What he found is that more and more people all over the world have begun to recognize three startling truths: Drugs are not what we think they are. Addiction is not what we think it is. And the drug war has very different motives to the ones we have seen on our TV screens for so long.In Chasing the Scream, Hari reveals his discoveries entirely through the stories of people across the world whose lives have been transformed by this war. They range from a transsexual crack dealer in Brooklyn searching for her mother, to a teenage hit-man in Mexico searching for a way out. It begins with Hari's discovery that at the birth of the drug war, Billie Holiday was stalked and killed by the man who launched this crusade--and it ends with the story of a brave doctor who has led his country to decriminalize every drug, from cannabis to crack, with remarkable results.Chasing the Scream lays bare what we really have been chasing in our century of drug war--in our hunger for drugs, and in our attempt to destroy them. This book will challenge and change how you think about one of the most controversial--and consequential--questions of our time.

    Teenage girls are taking courses of testosterone and disfiguring their bodies. Parents are undermined; experts are over-relied upon; dissenters in science and medicine are intimidated; free speech truckles under renewed attack; socialized medicine bears hidden consequences; and an intersectional era has arisen in which the desire to escape a dominant identity encourages individuals to take cover in victim groups. Every person who has ever had a skeptical thought about the sudden rush toward a non-binary future but been afraid to express it—this book is for you.

    He traces LSD's path from a promising psychiatric research medicine to a recreational drug sparking hysteria and prohibition. We follow Dr. Hofmann's trek across Mexico to discover sacred plants related to LSD, and listen in as he corresponds with other notable figures about his remarkable discovery. Underlying it all is Dr. Hofmann's powerful conclusion that mystical experience may be our planet's best hope for survival. Whether induced by LSD, meditation, or arising spontaneously, such experiences help us to comprehend "the wonder, the mystery of the divine‹in the microcosm of the atom, in the macrocosm of the spiral nebula, in the seeds of plants, in the body and soul of people." More than sixty years after the birth of Albert Hofmann's problem child, his vision of its true potential is more relevant, and more needed, than ever.

    Stephen Gundry believes that these defense strategies make the seemingly virtuous plants that we consume every day--fruits, vegetables, grains, nuts, and seeds--far less "good for us" than we assume. Dr. Gundry outlines the health hazards posed by lectins. The main sources of lectins in the American diet include conventionally-raised dairy products, beans, and other legumes, wheat and grains, and specific vegetables and fruitsWith a full list of lectin-containing foods and simple substitutes for each; a step-by-step detox and eating plan; and easy lectin-free recipes, The Plant Paradox illuminates the hidden dangers lurking in your salad bowl—and shows you how to eat whole foods in a whole new way.

    It has been inspired by the scientific ferment that swept through Britain at the end of the 18th century, and which Holmes now radically redefines as 'the revolution of Romantic Science'.

    hopeful news [for those] suffering from functional bowel disease.”  — New York Times Book ReviewDr. Gershon’s groundbreaking book fills the gap between what you need to know—and what your doctor has time to tell you.Dr. Michael Gershon has devoted his career to understanding the human bowel (the stomach, esophagus, small intestine, and colon). His thirty years of research have led to an extraordinary rediscovery: nerve cells in the gut that act as a brain. This "second brain" can control our gut all by itself. Our two brains—the one in our head and the one in our bowel—must cooperate. If they do not, then there is chaos in the gut and misery in the head—everything from "butterflies" to cramps, from diarrhea to constipation. Dr. Gershon's work has led to radical new understandings about a wide range of gastrointestinal problems including gastroenteritis, nervous stomach, and irritable bowel syndrome.The Second Brain represents a quantum leap in medical knowledge and is already benefiting patients whose symptoms were previously dismissed as neurotic or "it's all in your head."

    These “psychosurgeons,” as they called themselves, occupied a gray zone between medical research and medical practice, and ended up subjecting untold numbers of people to the types of surgical experiments once limited to chimpanzees.The most important test subject to emerge from this largely untold chapter in American history was a twenty-seven-year-old factory worker named Henry Molaison. In 1953, Henry—who suffered from severe epilepsy—received a radical new version of the lobotomy, one that targeted the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry left the operating room profoundly amnesic, unable to create new long-term memories. Over the next sixty years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.Luke Dittrich uses the case of Patient H.M. as a starting point for a kaleidoscopic journey, one that moves from the first recorded brain surgeries in ancient Egypt to the cutting-edge laboratories of MIT. He takes readers inside the old asylums and operating theaters where psychosurgeons conducted their human experiments, and behind the scenes of a bitter custody battle over the ownership of the most important brain in the world. Throughout, Dittrich delves into the enduring mysteries of the mind while exposing troubling stories of just how far we’ve gone in our pursuit of knowledge. It is also, at times, a deeply personal journey. Dittrich’s grandfather was the brilliant, morally complex surgeon who operated on Molaison—and thousands of other patients. The author’s investigation into the dark roots of modern memory science ultimately forces him to confront unsettling secrets in his own family history, and to reveal the tragedy that fueled his grandfather’s relentless experimentation—experimentation that would revolutionize our understanding of ourselves.Patient H.M. combines the best of biography, memoir, and science journalism to create a haunting, endlessly fascinating story, one that reveals the wondrous and devastating things that can happen when hubris, ambition, and human imperfection collide.

    What he discovered is a revolution under way—an explosion of new ideas about what cancer really is and where it comes from. In a provocative and intellectually vibrant exploration, he takes us on an adventure through the history and recent advances of cancer research that will challenge everything you thought you knew about the disease. Deftly excavating and illuminating decades of investigation and analysis, he reveals what we know and don’t know about cancer, showing why a cure remains such a slippery concept. We follow him as he combs through the realms of epidemiology, clinical trials, laboratory experiments, and scientific hypotheses—rooted in every discipline from evolutionary biology to game theory and physics. Cogently extracting fact from a towering canon of myth and hype, he describes tumors that evolve like alien creatures inside the body, paleo-oncologists who uncover petrified tumors clinging to the skeletons of dinosaurs and ancient human ancestors, and the surprising reversals in science’s comprehension of the causes of cancer, with the foods we eat and environmental toxins playing a lesser role. Perhaps most fascinating of all is how cancer borrows natural processes involved in the healing of a wound or the unfolding of a human embryo and turns them, jujitsu-like, against the body. Throughout his pursuit, Johnson clarifies the human experience of cancer with elegiac grace, bearing witness to the punishing gauntlet of consultations, surgeries, targeted therapies, and other treatments. He finds compassion, solace, and community among a vast network of patients and professionals committed to the fight and wrestles to comprehend the cruel randomness cancer metes out in his own family. For anyone whose life has been affected by cancer and has found themselves asking why?, this book provides a new understanding. In good company with the works of Atul Gawande, Siddhartha Mukherjee, and Abraham Verghese, The Cancer Chronicles is endlessly surprising and as radiant in its prose as it is authoritative in its eye-opening science.

    . . a book that enriches our understanding of how the struggle to think new thoughts is shared across time and space and people.”—The Sunday Telegraph (London)Christmas, 1859. Just one month after the publication of On the Origin of Species, Charles Darwin received an unsettling letter. He had expected criticism; in fact, letters were arriving daily, most expressing outrage and accusations of heresy. But this letter was different. It accused him of failing to acknowledge his predecessors, of taking credit for a theory that had already been discovered by others. Darwin realized that he had made an error in omitting from Origin of Species any mention of his intellectual forebears. Yet when he tried to trace all of the natural philosophers who had laid the groundwork for his theory, he found that history had already forgotten many of them.Darwin’s Ghosts tells the story of the collective discovery of evolution, from Aristotle, walking the shores of Lesbos with his pupils, to Al-Jahiz, an Arab writer in the first century, from Leonardo da Vinci, searching for fossils in the mine shafts of the Tuscan hills, to Denis Diderot in Paris, exploring the origins of species while under the surveillance of the secret police, and the brilliant naturalists of the Jardin de Plantes, finding evidence for evolutionary change in the natural history collections stolen during the Napoleonic wars. Evolution was not discovered single-handedly, Rebecca Stott argues, contrary to what has become standard lore, but is an idea that emerged over many centuries, advanced by daring individuals across the globe who had the imagination to speculate on nature’s extraordinary ways, and who had the courage to articulate such speculations at a time when to do so was often considered heresy.With each chapter focusing on an early evolutionary thinker, Darwin’s Ghosts is a fascinating account of a diverse group of individuals who, despite the very real dangers of challenging a system in which everything was presumed to have been created perfectly by God, felt compelled to understand where we came from. Ultimately, Stott demonstrates, ideas—including evolution itself—evolve just as animals and plants do, by intermingling, toppling weaker notions, and developing over stretches of time. Darwin’s Ghosts presents a groundbreaking new theory of an idea that has changed our very understanding of who we are.

    Sarno saved me from a life of pain.” — Howard Stern  The New York Times bestseller that has helped thousands leverage the mind-body connection to heal lower back pain and live pain free—without drugs, surgery, or physical therapy.  Offering a surprising, noninvasive solution to an epidemic of pain, Dr. John E. Sarno’s research on TMS (Tension Myoneural Syndrome) reveals that stress, anxiety and other psychological factors, not structural abnormalities, are the root cause of chronic pain. TMS develops as a result of repressed emotions which trigger tension in the body and deprive muscles and nerves of oxygen. The solution? Recognize the emotional roots of your TMS and sever the connection between mental and physical pain. With Dr. Sarno’s expert guidance you will learn:How the mind-body connection can permanently heal shoulder, neck, and lower back painHow accepting negative emotions like anger, anxiety, fear, or grief can reverse physical symptomsHow we condition ourselves to think back pain is inevitableWhy you should resume physical activity as soon as possibleSharing case histories and the results of his extensive, groundbreaking research, Dr. Sarno’s life-changing insights show readers how to banish back pain and reclaim their lives for good.