In 1996 Joseph LeDoux's "The Emotional Brain" presented a revelatory examination of the biological bases of our emotions and memories. Now, the world-renowned expert on the brain has produced with a groundbreaking work that tells a more profound story: how the little spaces between the neurons-the brain's synapses--are the channels through which we think, act, imagine, feel, and remember. Synapses encode the essence of personality, enabling each of us to function as a distinctive, integrated individual from moment to moment. Exploring the functioning of memory, the synaptic basis of mental illness and drug addiction, and the mechanism of self-awareness, "Synaptic Self" is a provocative and mind-expanding work that is destined to become a classic.

    Gina Rippon finally challenges this damaging myth by showing how the science community has engendered bias and stereotype by rewarding studies that show difference rather than sameness. Drawing on cutting edge research in neuroscience and psychology, Rippon presents the latest evidence which she argues, finally proves that brains are like mosaics comprised of both male and female components, and that they remain plastic, adapting throughout the course of a person’s life. Discernable gender identities, she asserts, are shaped by society where scientific misconceptions continue to be wielded and perpetuated to the detriment of our children, our own lives, and our culture.

    Far from preparing them for fulfilling relationships, viewing an endless stream of porn videos led to unexpected symptoms. Perhaps most surprisingly, for the first time in history erectile dysfunction was becoming a significant problem for young men. This led to one of the largest informal experiments in the history of science. Tens of thousands of people have tried abstaining from sexually stimulating material in a process they call ‘rebooting’. Many of them reported startling changes, from improved concentration and elevated mood to a greater capacity for real-life intimacy. Gary Wilson has listened to the stories of those who have tried giving up internet porn and related them to an account of how the reward system of the brain interacts with its environment. And now a growing body of research in neuroscience is confirming what these pioneers have discovered for themselves – internet pornography can be seriously addictive and damaging. In Your Brain on Porn Wilson provides a concise introduction to the phenomenon of internet porn addiction that draws on both first-person accounts and the findings of cognitive neuroscience. In a voice that is generous and humane, he also offers advice for those who want to stop using internet pornography. The publication of Your Brain on Porn is a landmark in our attempts to understand, and remain balanced in, a world where addiction is big business.

    But why are they on the rise?     Science writer Moises Velasquez-Manoff offers a new and controversial way of thinking about autoimmune disease—one that may foster a paradigm shift in the way we think about health and hygiene.     In the early twentieth century, the dawn of improved hygiene, water treatment, vaccines, and antibiotics saved countless lives, eradicating diseases that had plagued humanity for millennia. But in the wake of this triumph, a new threat arose: The human immune system began to malfunction.     A growing body of evidence suggests that the very steps we took to cure these maladies have also eradicated organisms that once kept our bodies in balance. To combat this “epidemic of absence,” a group of scientists has begun deliberately reintroducing parasitic worms—helminthes—to calm the immune system of their hosts. This book takes a close look at the scientists at the vanguard of “worm therapy,” which has been proven to not only preempt immune malfunction, but to send a number of disorders—from Crohn’s Disease to multiple sclerosis to asthma—into remission.     Exploring the greater context of rampant immune system dysfunction in the developed world, and its implications for developing countries, Velasquez-Manoff offers an eye-opening and elegant portrait of science’s new view of the human organism.

    A neurologist's insightful and compassionate look into the misunderstood world of psychosomatic disorders, told through individual case histories

    In this gripping account, David Quammen takes the reader along on this astonishing quest to learn how, where from, and why these diseases emerge and asks the terrifying question: What might the next big one be?

    This was the world of medicine when Thomas Dent Mütter began his trailblazing career as a plastic surgeon in Philadelphia during the middle of the nineteenth century.Although he died at just forty-eight, Mütter was an audacious medical innovator who pioneered the use of ether as anesthesia, the sterilization of surgical tools, and a compassion-based vision for helping the severely deformed, which clashed spectacularly with the sentiments of his time.   Brilliant, outspoken, and brazenly handsome, Mütter was flamboyant in every aspect of his life. He wore pink silk suits to perform surgery, added an umlaut to his last name just because he could, and amassed an immense collection of medical oddities that would later form the basis of Philadelphia’s Mütter Museum. Cristin O’Keefe Aptowicz chronicles how Mütter’s efforts helped establish Philadelphia as a global mecca for medical innovation—despite intense resistance from his numerous rivals.

    Four years in the writing, The Breakthrough is an "exciting read" about the discoveries which received the 2018 Nobel Prize winning discoveries in October, and a dramatic and exciting turning point in our relationship with a disease that has for too long defined us.For decades, scientists have puzzled over one of medicine's most confounding mysteries: Why doesn't our immune system recognize and fight cancer the way it does other diseases, like the common cold?As it turns out, the answer to that question can be traced to a series of tricks that cancer has developed to turn off normal immune responses-tricks that scientists have only recently discovered and learned to defeat. The result is what many are calling cancer's "penicillin moment," a revolutionary discovery in our understanding of cancer and how to beat it.In THE BREAKTHROUGH, Graeber guides readers through the revolutionary scientific research bringing immunotherapy out of the realm of the miraculous and into the forefront of twenty-first-century medical science. As advances in the fields of cancer research and the human immune system continue to fuel a therapeutic arms race among biotech and pharmaceutical research centers around the world, the next step-harnessing the wealth of new information to create modern and more effective patient therapies-is unfolding at an unprecedented pace, rapidly redefining our relationship with this all-too-human disease.Groundbreaking, riveting, and expertly told, THE BREAKTHROUGH is the story of the game-changing scientific discoveries that unleash our natural ability to recognize and defeat cancer, as told through the experiences of the patients, physicians, and cancer immunotherapy researchers who are on the front lines. This is the incredible true story of the race to find a cure, a dispatch from the life-changing world of modern oncological science, and a brave new chapter in medical history

    Or perhaps you're trying to find a nice way of dissuading someone from wasting money on a homeopathy cure. Or you met someone at a party who insisted the Holocaust never happened or that no one ever walked on the moon. How do you find a gently persuasive way of steering people away from unfounded beliefs, bogus cures, conspiracy theories, and the like? This down-to-earth, entertaining exploration of commonly held extraordinary claims will help you set the record straight. The author, a veteran journalist, has not only surveyed a vast body of literature, but has also interviewed leading scientists, explored "the most haunted house in America," frolicked in the inviting waters of the Bermuda Triangle, and even talked to a "contrite Roswell alien." He is not out simply to debunk unfounded beliefs. Wherever possible, he presents alternative scientific explanations, which in most cases are even more fascinating than the wildest speculation. For example, stories about UFOs and alien abductions lack good evidence, but science gives us plenty of reasons to keep exploring outer space for evidence that life exists elsewhere in the vast universe. The proof for Bigfoot or the Loch Ness Monster may be nonexistent, but scientists are regularly discovering new species, some of which are truly stranger than fiction.Stressing the excitement of scientific discovery and the legitimate mysteries and wonder inherent in reality, this book invites readers to share the joys of rational thinking and the skeptical approach to evaluating our extraordinary world.

    From the world’s most painful hornet, to the flies that transmit deadly diseases, to millipedes that stop traffic, to the “bookworms” that devour libraries, to the Japanese beetles munching on your roses, Wicked Bugs delves into the extraordinary powers of many-legged creatures. With wit, style, and exacting research, Stewart has uncovered the most terrifying and titillating stories of bugs gone wild. It’s an A to Z of insect enemies, interspersed with sections that explore bugs with kinky sex lives (“She’s Just Not That Into You”), creatures lurking in the cupboard (“Fear No Weevil”), insects eating your tomatoes (“Gardener’s Dirty Dozen”), and phobias that feed our (sometimes) irrational responses to bugs (“Have No Fear”). Intricate and strangely beautiful etchings and drawings by Briony Morrow-Cribbs capture diabolical bugs of all shapes and sizes in this mixture of history, science, murder, and intrigue that begins—but doesn’t end—in your own backyard.

    And certainly no one wants to overeat for years, become overweight, and end up with a high risk of diabetes or heart disease--yet two thirds of Americans do precisely that. Even though we know better, we often eat too much. Why does our behavior betray our own intentions to be lean and healthy? The problem, argues obesity and neuroscience researcher Stephan J. Guyenet, is not necessarily a lack of willpower or an incorrect understanding of what to eat. Rather, our appetites and food choices are led astray by ancient, instinctive brain circuits that play by the rules of a survival game that no longer exists. And these circuits don’t care about how you look in a bathing suit next summer.To make the case, The Hungry Brain takes readers on an eye-opening journey through cutting-edge neuroscience that has never before been available to a general audience. The Hungry Brain delivers profound insights into why the brain undermines our weight goals and transforms these insights into practical guidelines for eating well and staying slim. Along the way, it explores how the human brain works, revealing how this mysterious organ makes us who we are.

    It will make you angry. It will amaze you with the courage of some of the people described in the book...The Autoimmune Epidemic is every bit as compelling as Upton Sinclair's The Jungle...It is also every bit as necessary as An Inconvenient Truth.... You will leave this book with no reservations about the veracity of the conclusions: put simply, there is no doubt that autoimmune diseases are on the rise and increasing environmental exposures of toxins and chemicals is fueling this rise. The research is sound. The conclusions unassailable.... Reading The Autoimmune Epidemic is a necessary first step. Reading The Autoimmune Epidemic is a life-altering event. It needs to be."

    You're not stuck with the brain you're born with. Here are just a few of neuropsychiatrist Dr. Daniel Amen's surprising--and effective--"brain prescriptions" that can help heal your brain and change your life:To Quell Anxiety and Panic: ¸  Use simple breathing techniques to immediately calm inner turmoilTo Fight Depression: ¸  Learn how to kill ANTs (automatic negative thoughts)To Curb Anger: ¸  Follow the Amen anti-anger diet and learn the nutrients that calm rageTo Conquer Impulsiveness and Learn to Focus: ¸  Develop total focus with the "One-Page Miracle"To Stop Obsessive Worrying: ¸  Follow the "get unstuck" writing exercise and learn other problem-solving exercises

    We rely on them every day of our lives. They make us who we are. And yet the truth is they are far from being the accurate record of the past we like to think they are. True, we can all admit to having suffered occasional memory lapses, such as entering a room and immediately forgetting why, or suddenly being unable to recall the name of someone we've met dozens of times. But what if our minds have the potential for more profound errors, that enable the manipulation or even outright fabrication of our memories?In The Memory Illusion, forensic psychologist and memory expert Dr Julia Shaw uses the latest research to show the astonishing variety of ways in which our brains can indeed be led astray. She shows why we can sometimes misappropriate other people's memories, subsequently believing them to be our own. She explains how police officers can imprison an innocent man for life on the basis of many denials and just one confession. She demonstrates the way radically false memories can be deliberately implanted, leading people to believe they had tea with Prince Charles, or committed crimes that never happened. And she reveals how, in spite of all this, we can improve our memory through simple awareness of its fallibility. Fascinating and unnerving in equal measure, The Memory Illusion offers a unique insight into the human brain, challenging you to question how much you can ever truly know about yourself.

    From the classroom to the courtroom and from financial markets to supermarkets, Mlodinow's intriguing and illuminating look at how randomness, chance, and probability affect our daily lives will intrigue, awe, and inspire.