What at first seemed like a case of food poisoning quickly turned critical, and by the time Tom had been transferred via emergency medevac to the world-class medical center at UC San Diego, where both he and Steffanie worked, blood work revealed why modern medicine was failing: Tom was fighting one of the most dangerous, antibiotic-resistant bacteria in the world.Frantic, Steffanie combed through research old and new and came across phage therapy: the idea that the right virus, aka "the perfect predator," can kill even the most lethal bacteria. Phage treatment had fallen out of favor almost 100 years ago, after antibiotic use went mainstream. Now, with time running out, Steffanie appealed to phage researchers all over the world for help. She found allies at the FDA, researchers from Texas A&M, and a clandestine Navy biomedical center -- and together they resurrected a forgotten cure.

    After World War II, Don's work with the Air Force brought them to Colorado, where their twelve children perfectly spanned the baby boom: the oldest born in 1945, the youngest in 1965. In those years, there was an established script for a family like the Galvins—aspiration, hard work, upward mobility, domestic harmony—and they worked hard to play their parts. But behind the scenes was a different story: psychological breakdown, sudden shocking violence, hidden abuse. By the mid-1970s, six of the ten Galvin boys, one after another, were diagnosed as schizophrenic. How could all this happen to one family?What took place inside the house on Hidden Valley Road was so extraordinary that the Galvins became one of the first families to be studied by the National Institute of Mental Health. Their story offers a shadow history of the science of schizophrenia, from the era of institutionalization, lobotomy, and the schizophrenogenic mother to the search for genetic markers for the disease, always amid profound disagreements about the nature of the illness itself. And unbeknownst to the Galvins, samples of their DNA informed decades of genetic research that continues today, offering paths to treatment, prediction, and even eradication of the disease for future generations.With clarity and compassion, bestselling and award-winning author Robert Kolker uncovers one family's unforgettable legacy of suffering, love, and hope.

    In memoirs, essays and stories that are funny, moving, visionary or insightful, twenty-three famous writers celebrate these places where minds open and the world expands.Public libraries are lifelines, to practical information as well as to the imagination, but funding is under threat all over the country. This book is published in support of libraries, with all royalties going to The Reading Agency's library programmes.

    As Professor of Anatomy and Forensic Anthropology, she focuses on mortal remains in her lab, at burial sites, at scenes of violence, murder and criminal dismemberment, and when investigating mass fatalities due to war, accident or natural disaster. In All that Remains she reveals the many faces of death she has come to know, using key cases to explore how forensic science has developed, and what her work has taught her. Do we expect a book about death to be sad? Macabre? Sue’s book is neither. There is tragedy, but there is also humour in stories as gripping as the best crime novel. Our own death will remain a great unknown. But as an expert witness from the final frontier, Sue Black is the wisest, most reassuring, most compelling of guides.

    And with a thump, down came Father Iggy.From shoot-outs at funerals to dead men screaming and runaway corpses, undertakers have plenty of unusual stories to tell--and a special way of telling them.In this macabre and moving compilation, funeral directors across the country share their most embarrassing, jaw-dropping, irreverent, and deeply poignant stories about life at death's door. Discover what scares them and what moves them to tears. Learn about rookie mistakes and why death sometimes calls for duct tape.Enjoy tales of the dearly departed spending eternity naked from the waist down and getting bottled and corked--in a wine bottle. And then meet their families--the weepers, the punchers, the stolidly dignified, and the ones who deliver their dead mother in a pickup truck.If there's one thing undertakers know, it's that death drives people crazy. These are the best "bodies of work" from America's darkest profession."Sick, funny, and brilliant! I love this book." --Jonathan Maberry

    In this riveting collection of thoughts and stories, Paulo Coelho, the author of 'The Alchemist', offers his personal reflections on a wide range of subjects from archery and music to elegance, traveling and the nature of good and evil. An old woman explains to her grandson how a mere pencil can show him the path to happiness...instructions on how to climb a mountain reveal the secret to making your dreams a reality!the story of Ghengis Khan and the Falcon that teaches about the folly of anger - and the art of friendship!a pianist who performs an example in fulfilling your destiny!the author learns three important lessons when he goes to the rescue of a man in the street - Paulo shows us how life has lessons for us in the greatest, smallest and most unusual of experiences. 'Like the Flowing River' includes jewel-like fables, packed with meaning and retold in Coelho's inimitable style. Sharing his thoughts on spirituality, life and ethics, Paulo touches you with his philosophy and invites you to go on an exciting journey of your own.

    For decades after the structure of DNA was identified, scientists focused purely on genes, the regions of the genome that contain codes for the production of proteins. Other regions - 98% of the human genome - were dismissed as 'junk'. But in recent years researchers have discovered that variations in this 'junk' DNA underlie many previously intractable diseases, and they can now generate new approaches to tackling them. Nessa Carey explores, for the first time for a general audience, the incredible story behind a controversy that has generated unusually vituperative public exchanges between scientists. She shows how junk DNA plays an important role in areas as diverse as genetic diseases, viral infections, sex determination in mammals, human biological complexity, disease treatments, even evolution itself - and reveals how we are only now truly unlocking its secrets, more than half a century after Crick and Watson won their Nobel prize for the discovery of the structure of DNA in 1962.

    Our books shape us, define us, enchant us, and even sometimes infuriate us. Our books are a part of who we are as people, and we can't imagine life without them.I'd Rather Be Reading is the perfect literary companion for everyone who feels that way. In this collection of charming and relatable reflections on the reading life, beloved blogger and author Anne Bogel leads readers to remember the book that first hooked them, the place where they first fell in love with reading, and all of the moments afterward that helped make them the reader they are today. Known as a reading tastemaker through her popular podcast What Should I Read Next?, Bogel invites book lovers into a community of like-minded people to discover new ways to approach literature, learn fascinating new things about books and publishing, and reflect on the role reading plays in their lives.The perfect gift for the bibliophile in everyone's life, I'd Rather Be Reading will command an honored place on the overstuffed bookshelves of any book lover.

    Like twelve million other Americans, Sandra Beasley suffers from food allergies. Her allergies—severe and lifelong—include dairy, egg, soy, beef, shrimp, pine nuts, cucumbers, cantaloupe, honeydew, mango, macadamias, pistachios, cashews, swordfish, and mustard. Add to that mold, dust, grass and tree pollen, cigarette smoke, dogs, rabbits, horses, and wool, and it’s no wonder Sandra felt she had to live her life as “Allergy Girl.” When butter is deadly and eggs can make your throat swell shut, cupcakes and other treats of childhood are out of the question—and so Sandra’s mother used to warn guests against a toxic, frosting-tinged kiss with “Don’t kill the birthday girl!” It may seem that such a person is “not really designed to survive,” as one blunt nutritionist declared while visiting Sandra’s fourth-grade class. But Sandra has not only survived, she’s thrived—now an essayist, editor, and award-winning poet, she has learned to navigate a world in which danger can lurk in an unassuming corn chip. Don’t Kill the Birthday Girl is her story. With candor, wit, and a journalist’s curiosity, Sandra draws on her own experiences while covering the scientific, cultural, and sociological terrain of allergies. She explains exactly what an allergy is, describes surviving a family reunion in heart-of-Texas beef country with her vegetarian sister, delves into how being allergic has affected her romantic relationships, exposes the dark side of Benadryl, explains how parents can work with schools to protect their allergic children, and details how people with allergies should advocate for themselves in a restaurant. A compelling mix of memoir, cultural history, and science, Don’t Kill the Birthday Girl is mandatory reading for the millions of families navigating the world of allergies—and a not-to-be-missed literary treat for the rest of us.

    Performing as a living statue in a wedding dress, she wordlessly asked thousands of passersby for their dollars. When she became a singer, songwriter, and musician, she was not afraid to ask her audience to support her as she surfed the crowd (and slept on their couches while touring). And when she left her record label to strike out on her own, she asked her fans to support her in making an album, leading to the world's most successful music Kickstarter.Even while Amanda is both celebrated and attacked for her fearlessness in asking for help, she finds that there are important things she cannot ask for-as a musician, as a friend, and as a wife. She learns that she isn't alone in this, that so many people are afraid to ask for help, and it paralyzes their lives and relationships. In this groundbreaking book, she explores these barriers in her own life and in the lives of those around her, and discovers the emotional, philosophical, and practical aspects of The Art Of Asking.Part manifesto, part revelation, this is the story of an artist struggling with the new rules of exchange in the twenty-first century, both on and off the Internet. The Art Of Asking will inspire readers to rethink their own ideas about asking, giving, art, and love.

    

    The heart of her work on her national public radio program and podcast, On Being, has been to shine a light on people whose insights kindle in us a sense of wonder and courage. Scientists in a variety of fields; theologians from an array of faiths; poets, activists, and many others have all opened themselves up to Tippett's compassionate yet searching conversation.   In Becoming Wise, Tippett distills the insights she has gleaned from this luminous conversation in its many dimensions into a coherent narrative journey, over time and from mind to mind. The book is a master class in living, curated by Tippett and accompanied by a delightfully ecumenical dream team of teaching faculty.   The open questions and challenges of our time are intimate and civilizational all at once, Tippett says – definitions of when life begins and when death happens, of the meaning of community and family and identity, of our relationships to technology and through technology. The wisdom we seek emerges through the raw materials of the everyday. And the enduring question of what it means to be human has now become inextricable from the question of who we are to each other.   This book offers a grounded and fiercely hopeful vision of humanity for this century – of personal growth but also renewed public life and human spiritual evolution. It insists on the possibility of a common life for this century marked by resilience and redemption, with beauty as a core moral value and civility and love as muscular practice. Krista Tippett's great gift, in her work and in Becoming Wise, is to avoid reductive simplifications but still find the golden threads that weave people and ideas together into a shimmering braid.   One powerful common denominator of the lessons imparted to Tippett is the gift of presence, of the exhilaration of engagement with life for its own sake, not as a means to an end. But presence does not mean passivity or acceptance of the status quo. Indeed Tippett and her teachers are people whose work meets, and often drives, powerful forces of change alive in the world today. In the end, perhaps the greatest blessing conveyed by the lessons of spiritual genius Tippett harvests in Becoming Wise is the strength to meet the world where it really is, and then to make it better.

    A Slip of the Keyboard brings together for the first time the finest examples of Pratchett's non fiction writing, both serious and surreal: from musings on mushrooms to what it means to be a writer (and why banana daiquiris are so important); from memories of Granny Pratchett to speculation about Gandalf's love life, and passionate defences of the causes dear to him.With all the humour and humanity that have made his novels so enduringly popular, this collection brings Pratchett out from behind the scenes of the Discworld to speak for himself - man and boy, bibliophile and computer geek, champion of hats, orang-utans and Dignity in Dying.

    Today he is the director of the Center for Compassion and Altruism Research and Education (CCARE) at Stanford University, of which the Dalai Lama is a founding benefactor. But back then his life was at a dead end until at twelve he wandered into a magic shop looking for a plastic thumb. Instead he met Ruth, a woman who taught him a series of exercises to ease his own suffering and manifest his greatest desires. Her final mandate was that he keep his heart open and teach these techniques to others. She gave him his first glimpse of the unique relationship between the brain and the heart.Doty would go on to put Ruth’s practices to work with extraordinary results—power and wealth that he could only imagine as a twelve-year-old, riding his orange Sting-Ray bike. But he neglects Ruth’s most important lesson, to keep his heart open, with disastrous results—until he has the opportunity to make a spectacular charitable contribution that will virtually ruin him. Part memoir, part science, part inspiration, and part practical instruction, Into the Magic Shop shows us how we can fundamentally change our lives by first changing our brains and our hearts.

    She draws from her own experiences of illness and bodily injury to engage in an exploration that extends far beyond her life, spanning wide-ranging territory—from poverty tourism to phantom diseases, street violence to reality television, illness to incarceration—in its search for a kind of sight shaped by humility and grace.