With more than one in every five people over the age of fourteen addicted, drug abuse has been called the most formidable health problem worldwide. If we are not victims ourselves, we all know someone struggling with the merciless compulsion to alter their experience by changing how their brain functions.Drawing on years of research--as well as personal experience as a recovered addict--researcher and professor Judy Grisel has reached a fundamental conclusion: for the addict, there will never be enough drugs. The brain's capacity to learn and adapt is seemingly infinite, allowing it to counteract any regular disruption, including that caused by drugs. What begins as a normal state punctuated by periods of being high transforms over time into a state of desperate craving that is only temporarily subdued by a fix, explaining why addicts are unable to live either with or without their drug. One by one, Grisel shows how different drugs act on the brain, the kind of experiential effects they generate, and the specific reasons why each is so hard to kick.Grisel's insights lead to a better understanding of the brain's critical contributions to addictive behavior, and will help inform a more rational, coherent, and compassionate response to the epidemic in our homes and communities.

    Nina Stibbe's Love, Nina: Despatches from Family Life is the laugh-out-loud story of the trials and tribulations of a very particular family.

    Yankee Doodle called his feathered cap "Macaroni."

    Hitchins doesn’t shy away from his failures or celebrate his mild successes — he sacrifices them for an audience’s amusement. He roasts his younger self, the effeminate ginger-haired kid with a competitive streak. The ups and downs of being a sperm donor to a lesbian couple. Then the fiery redhead professes his love for actress Shelley Long, declares his hatred of musical theatre, and recounts a summer spent in Provincetown working as a drag queen.Nothing is sacred. His first major break-up, how his mother plotted the murder of the family cat, his difficult relationship with his father, becoming an unintentional spokesperson for all redheads, and mandy moore many more.Blunt, awkward, emotional, ribald, this anthology of humiliation culminates in a greater understanding of love, work, and family. Like the final scene in a Murder She Wrote episode, A Brief History of Oversharing promises everyone the A-ha! moment Oprah tells us to experience. Paired with bourbon, Scottish wool, and Humpty Dumpty Party Mix, this journey is best read through a lens of schadenfreude.

    The remaining twenty percent, however, are socially maladjusted psychopaths. WAITER RANT offers the server's unique point of view, replete with tales of customer stupidity, arrogant misbehavior, and unseen bits of human grace transpiring in the most unlikely places. Through outrageous stories, The Waiter reveals the secrets to getting good service, proper tipping etiquette, and how to keep him from spitting in your food. The Waiter also shares his ongoing struggle, at age thirty-eight, to figure out if he can finally leave the first job at which he's really thrived."The other shoe finally drops. The front-of-the-house version of Kitchen Confidential; a painfully funny, excruciatingly true-life account of the waiter's life. As useful as it is entertaining. You will never look at your waiter the same way again�and will never tip less than 20%." --Anthony Bourdain, author of Kitchen Confidential"I really enjoyed WAITER RANT. The book is engaging and funny, a story told from my polar opposite perspective. I will now do my best to act better as a Chef -- and I dare say, I'll never be rude to a waiter again, as long as I live."--John DeLucie, Chef of The Waverly Inn

    This is a book for anyone who has ever failed. Which means it’s a book for everyone. If I have learned one thing from this shockingly beautiful venture called life, it is this: failure has taught me lessons I would never otherwise have understood. I have evolved more as a result of things going wrong than when everything seemed to be going right. Out of crisis has come clarity, and sometimes even catharsis.Part memoir, part manifesto, and including chapters on dating, work, sport, babies, families, anger and friendship, it is based on the simple premise that understanding why we fail ultimately makes us stronger. It's a book about learning from our mistakes and about not being afraid. Uplifting, inspiring and rich in stories from Elizabeth’s own life, How to Fail reveals that failure is not what defines us; rather it is how we respond to it that shapes us as individuals. Because learning how to fail is actually learning how to succeed better. And everyone needs a bit of that.