This simple way to manage your household income and expenses includes a stylish cover, coin purse, places for your checkbook and check register, memo pad, debit card holders, and extra cash-management envelopes.

    Some of these drugs are truly transformative, offering major improvements in how long patients live or how they feel--but what is often missing from the popular narrative is that, far too often, these new drugs have marginal or minimal benefits. Some are even harmful. In Malignant, hematologist-oncologist Dr. Vinayak K. Prasad writes about the many sobering examples of how patients are too often failed by cancer policy and by how oncology is practiced. Throughout this work, Prasad illuminates deceptive practices which- promote novel cancer therapies long before credible data are available to support such treatment; and- exaggerate the potential benefits of new therapies, many of which cost thousands and in some cases hundreds of thousands of dollars.Prasad then critiques the financial conflicts of interest that pervade the oncology field, the pharmaceutical industry, and the US Food and Drug administration.This is a book about how the actions of human beings--our policies, our standards of evidence, and our drug regulation--incentivize the pursuit of marginal or unproven therapies at lofty and unsustainable prices. Prasad takes us through how cancer trials are conducted, how drugs come to market, and how pricing decisions are made, asking how we can ensure that more cancer drugs deliver both greater benefit and a lower price. Ultimately, Prasad says,- more cancer clinical trials should measure outcomes that actually matter to people with cancer;- patients on those trials should look more like actual global citizens;- we need drug regulators to raise, not perpetually lower, the bar for approval; and- we need unbiased patient advocates and experts.This well-written, opinionated, and engaging book explains what we can do differently to make serious and sustained progress against cancer--and how we can avoid repeating the policy and practice mistakes of the past.

    The Big Questions series is designed to let renowned experts address the 20 most fundamental and frequently asked questions of a major branch of science or philosophy. Each 3,000-word essay simply and concisely examines a question that has eternally perplexed enquiring minds, and provides answers based on the latest research. This ambitious project is a unique distillation of humanity's best ideas. In "The Big Questions: Evolution," Francisco Ayala answers the 20 key questions: What is evolution? Was Darwin right? What is natural selection? What is survival of the fittest? Is evolution a random process? What is a species? What are chromosomes, genes and DNA? How do genes build bodies? What is molecular evolution? How did life begin? What is the tree of life? Am I really a monkey? What does the fossil record tell us? What is the missing link? Is intelligence inherited? Will humans continue to evolve? Can I clone myself? Where does morality come from? Is language a uniquely human attribute? Is Creationism true?

    No rock, leaf, or cubic foot of air on Earth has escaped humanity's signature. The old distinctions—between natural and artificial, dystopia and utopia, science fiction and science fact—have blurred, losing all meaning. We inhabit an uncanny landscape of our own creation. In Second Nature, ordinary people make desperate efforts to preserve their humanity in a world that seems increasingly alien. Their stories—obsessive, intimate, and deeply reported—point the way to a new kind of environmental literature, in which dramatic narrative helps us to understand our place in a reality that resembles nothing human beings have known.From Odds Against Tomorrow to Losing Earth to the film Dark Waters (adapted from the first chapter of this book), Nathaniel Rich’s stories have come to define the way we think of contemporary ecological narrative. In Second Nature, he asks what it means to live in an era of terrible responsibility. The question is no longer, How do we return to the world that we’ve lost?It is, What world do we want to create in its place?

    Through fascinating portraits of a wide array of creatures, he introduces us to the many forms of sea life that humans have fished, hunted, and collected over the centuries, from charismatic whales and dolphins to the lowly menhaden, from sea turtles to cod, tuna, and coral.Rich in history, anecdote, and surprising fact, Richard Ellis’s descriptions bring to life the natural history of the various species, the threats they face, and the losses they have suffered. Killing has occurred on a truly stunning scale, with extinction all too often the result, leaving a once-teeming ocean greatly depleted. But the author also finds instances of hope and resilience, of species that have begun to make remarkable comebacks when given the opportunity.Written with passion and grace, and illustrated with Richard Ellis’s own drawings, The Empty Ocean brings to a wide audience a compelling view of the damage we have caused to life in the sea and what we can do about it. "

    In his hallmark friendly style, he explores the universal impact of being the right size. By examining stories ranging from Alice in Wonderland to Gulliver's Travels, he shows that humans have always been fascinated by things big and small. Why then does size always reside on the fringes of science and never on the center stage? Why do biologists and others ponder size only when studying something else--running speed, life span, or metabolism? Why Size Matters, a pioneering book of big ideas in a compact size, gives size its due by presenting a profound yet lucid overview of what we know about its role in the living world. Bonner argues that size really does matter--that it is the supreme and universal determinant of what any organism can be and do. For example, because tiny creatures are subject primarily to forces of cohesion and larger beasts to gravity, a fly can easily walk up a wall, something we humans cannot even begin to imagine doing.Bonner introduces us to size through the giants and dwarfs of human, animal, and plant history and then explores questions including the physics of size as it affects biology, the evolution of size over geological time, and the role of size in the function and longevity of living things.As this elegantly written book shows, size affects life in its every aspect. It is a universal frame from which nothing escapes.

    Dumb crooks, celebrities gone bad, unsolved mysteries, odd laws, and more—Strange Crime has plenty of stories that will make you ask yourself, “What could they possibly have been thinking?” This easily portable paperback book is ideal for readers on the go. Take it to school, to work, to jury duty!

    And survival is never a given. Somehow, a blind, defenseless tiger kitten must evolve into a deadly, efficient predator; a chimp must learn to distinguish edible plants from lethal poisons; a baby buffalo must be able to pick its mother out of a herd of hundreds. Contrary to common belief, not everything is "hardwired" -- or instinctual -- in the animal kingdom. Many skills a wild animal needs to thrive, to grow, to be what nature intended, must be developed through play, painstaking teaching, and often treacherous trial and error. The coming-of-age processes of the myriad creatures of plain, forest, ocean, and jungle are truly fascinating and often astonishing natural events.In Becoming a Tiger, Susan McCarthy, co-author of the critically acclaimed New York Times bestseller When Elephants Weep, offers readers an in-depth look into the amazing ways baby animals learn not only about themselves, but about their world and ours -- and how to survive in both. Based on extensive scientific research done in the lab, in controlled "natural" settings, as well as in the wild, her findings provide stunning new insights into the lives and development of Earth's nonhuman inhabitants -- not only tigers, but lions, bears, bats, rats, birds, dolphins, whales, apes, elephants, and dozens of other species.Sharing stories and discoveries at once captivating, funny, breathtaking, provocative, and heartwarming, Susan McCarthy carries us on a remarkable journey into untamed places, immersing us in the fascinating, complex, and hitherto unimagined societies and cultures of the beasts and birds. Along the way she shines a brilliant new light on subjects scientists, biologists, and zoologists have only begun to explore, revealing startling truths about the behavior, and sometimes humanlike foibles, of creatures great and small.Warm, informative, and beautifully written, Becoming a Tiger is an enthralling reading experience for animal lovers everywhere. In the transformation tales of playful pups, big-footed cubs, and scrawny chicks becoming deadly hunters, able foragers, and deft nest-builders are valuable and enriching life lessons for members of our own inquisitive, ever-developing species.

    Kirsch, M.D., an Orthopedic Surgeon for the common man. It is the result of 25 years of research into a new and simple exercise to prevent rotator cuff tears and impingement syndrome in the shoulder, as well as treating these conditions and frozen shoulder. Testimonials and research CT scan images are included as well as images of the exercises performed by models and patients.

    Ehrlich, author of The Dominant Animal  Biologist Rob Dunn’s Every Little Thing is the story of man’s obsessive quest to catalog life, from nanobacteria to new monkeys. In the tradition of E.O. Wilson, this engaging and fascinating work of popular science follows humanity’s unending quest to discover every living thing in our natural world—from the unimaginably small in the most inhospitable of places on earth to the unimaginably far away in the unexplored canals on Mars.

    This 8-hour free course introduced the study of philosophy and the methods employed by The Open University in teaching philosophy.

    The images were taken when Banksy joined Bristol's radical football team The Easton Cowboys on a tour of Mexico to play football against the Zapatista freedom fighters. The new edition also contains sections on the Banksy vs Bristol Museum show, Exit Through The Gift Shop, The Tesco Value Petrol Bomb, an interview with John Nation and more. The book is a celebration of Banksy's street art in his home city of Bristol and places him in the context of 3D, John Nation from the Barton Hill Youth Club, Inkie, Nick Walker and the other artists and musicians who were instrumental in linking Bristol to the original New York hip-hop scene. It is the most revealing account of Banksy's formative years and contains more than one hundred images of his Bristol art, as well as pictures of Banksy at work, many of which have never been published before. Steve Wright, traces Banksy's roots back to the rave culture of the Nineties and draws a rounded picture of an artist who is most famous for being anonymous.

    In his own lifetime, Suzuki has witnessed an explosion of scientific knowledge as well as a huge change in our relationship with the planet-a tripling of the world's population, a greatly increased ecological footprint through the global economy, and a huge growth in technological capacity. These changes have had a dire effect on Earth's ecosystems and consequently on our own well-being. To deal with this crisis, we must realize that the laws of nature have priority over the forces of economics and that the planet simply cannot sustain unfettered growth. We must also recognize the limits of scientific reductionism and the need to adopt a more holistic point of view. Perhaps most important, we must join together as a single species to respond to the problems we face. Suzuki ends by saying that change begins with each of us; all it takes is imagination and a faith in the inherent generosity of Mother Earth.Published in partnership with the David Suzuki Foundation. Also available in hardcover.

    Human waste, once considered a gift to the soil, has become toxic material that has broken the essential cycle of decay and regeneration. Here, award-winning author Derrick Jensen and activist Aric McBay weave historical analysis and devastatingly beautiful prose to remind us that life--human and nonhuman--will not go on unless we do everything we can to facilitate the most basic process on earth, the root of sustainability: one being's waste must always become another being's food.

    From constructing coops to rearing chicks, you’ll learn everything you need to know to make sure your chickens stay happy and healthy all year round.Which breed of chicken is right for you? What’s the best coop-bedding material? What sort of feed should you use? Let expert chicken keeper Anne Kuo answer these questions—and many others—in The Beginner’s Guide to Raising Chickens.The Beginner’s Guide to Raising Chickens includes: All cooped up—Create the perfect home for raising chickens using detailed backyard coop designs and construction guides. From chickens to eggs—Find out how to pick the right breed, raise chicks, collect eggs, keep your birds safe from predators, and more. Learn to speak bird—Start talking the talk thanks to an extensive glossary of common chicken-keeping terms. Get your own flock started in no time—The Beginner’s Guide to Raising Chickens shows you how.