Just a half century ago, this idea was revolutionary. In April 1953, James Watson and Francis Crick published in Nature their groundbreaking work revealing the double helix structure of DNA. While this discovery received wide attention from both mainstream media and the academic community, it was just one part of the bigger story in this history of molecular biology. By the mid-1950s, the scientific community confirmed that genes were indeed comprised of DNA; they just needed to crack the genetic code—and the race was on. Life’s Greatest Secret is the full and rich history of this challenge and the characters—many of whom were not biologists—whose work contributed to this grand scientific endeavor: mathematician and father of cybernetics Norbert Wiener, physicist Erwin Schrödinger, information theorist Claude Shannon, and biologists Jacques Monod and Marshall Nirenberg.In Life’s Greatest Secret, science historian and zoologist Matthew Cobb shows that the race to crack the genetic code was mostly a matter of craft—individuals or small groups struggling with ideas and concepts as much as they were with facts, trying to find the right experiment to answer the right questions, even if they didn’t know what the questions were, and finding that, even when the most definitive answer served mostly to reveal more ignorance, whether in 1953, with Watson and Crick, or in 1961, when Nirenberg and Matthaei showed how DNA codes for specific amino acids, and again and again thereafter, or in 2000, with the first publication of a human genome. Each discovery was a leap forward in our understanding of the natural world and our place within in, akin to the discoveries of Galileo and Einstein in the realm of physics, or the publication of Darwin’s On the Origin of Species. And each served to show how much bigger the problem was that anyone had previously imagined, a trend that continues, as Cobb shows, even today, whether we are discussing gene regulation, epigenetics, or GMOs.Life’s Greatest Secret is a story of ideas and of experimentation, of ingenuity, insight, and dead-ends, in the hunt to make the greatest discovery of twentieth century biology. Ultimately, though, this is a story of humans exploring what it is that makes us human.

    This is just as well, according to Mark Lynas in Nuclear 2.0, because nuclear energy is essential to avoid catastrophic global warming. Using the latest world energy statistics Lynas shows that with wind and solar still at only about 1 percent of global primary energy, asking renewables to deliver all the world’s power is “dangerously delusional”. Moreover, there is no possibility of using less energy, he reminds us, when the developing world is fast extricating itself from poverty and adding the equivalent of a new Brazil to global electricity consumption each year. The anti-nuclear movement of the 1970s and 80s succeeded only in making the world more dependent on fossil fuels, he shows: its history is “not lit by sunshine, but shrouded in coal smoke”. Instead of making the same mistake again, all those who want to see a low-carbon future need to join forces, he insists, concluding the book with an ambitious proposal for an Apollo Program-style combined investment in wind, solar and nuclear power. Mark Lynas is an environmental writer and campaigner. His previous books have drawn attention to the perils of global warming, and he was Climate Advisor to the President of the Maldives from 2009-2011. He is a Visiting Research Associate at Oxford University’s School of Geography and the Environment, and a member of the World Economic Forum’s Global Agenda Council on Emerging Technologies. He recently featured in the movie documentary Pandora’s Promise, which inspired the writing of this book.

    David Horowitz’s classic Why Israel is the Victim, updated by the author, sets the record straight about the basic truths of the Middle East conflict. In addition to restoring the authentic history of the region – a history of obsessive aggression first by Arab countries determined to physically annihilate the Jewish State and later by terror groups determined to destroy its will to survive and right to exist—this booklet brings the story up to date by showing the systematic way in which Hamas and Hezbollah, under Iran’s direction, have subverted peace in the Middle East. As Shillman Fellow Daniel Greenfield notes in his insightful introduction, this pamphlet “tells us why we should reject the “Blame Israel First” narrative that has so thoroughly saturated the mainstream media… It confronts the myth of Palestinian victimhood… and it delivers a rousing restatement of the true history of the hate that led us to all this.” America should be Israel’s protector. Instead, as David Horowitz notes, under the leadership of Barack Obama, it has become its prosecutor.

    It is within the realm of possibility that their work may usher in a change in global economics as profound as the Industrial Revolution. As may be expected, press reports dealing with asteroid mining have been numerous, ranging in scope from short and breezy to broad and serious, and in quality from accurate to impressionistic to simply uninformed. There is good reason to be curious about what may be the biggest game-changer in human economic history. And there is good reason to look closely at the underlying science and engineering that form the foundation of this work.

    C. R. Licklider, Doug Engelbart, Bob Taylor, and Alan Kay.The digital revolution did not begin with the teenage millionaires of Silicon Valley, claims Howard Rheingold, but with such early intellectual giants as Charles Babbage, George Boole, and John von Neumann. In a highly engaging style, Rheingold tells the story of what he calls the patriarchs, pioneers, and infonauts of the computer, focusing in particular on such pioneers as J. C. R. Licklider, Doug Engelbart, Bob Taylor, and Alan Kay. Taking the reader step by step from nineteenth-century mathematics to contemporary computing, he introduces a fascinating collection of eccentrics, mavericks, geniuses, and visionaries.The book was originally published in 1985, and Rheingold's attempt to envision computing in the 1990s turns out to have been remarkably prescient. This edition contains an afterword, in which Rheingold interviews some of the pioneers discussed in the book. As an exercise in what he calls retrospective futurism, Rheingold also looks back at how he looked forward.

    

    Drawing partly on his own career—from young scientist in awe of his elders to crotchety elder statesman—Tattersall offers an idiosyncratic look at the competitive world of paleoanthropology, beginning with Charles Darwin 150 years ago, and continuing through the Leakey dynasty in Africa, and concluding with the latest astonishing findings in the Caucasus.The book's title refers to the 1856 discovery of a clearly very old skull cap in Germany's Neander Valley. The possessor had a brain as large as a modern human, but a heavy low braincase with a prominent brow ridge. Scientists tried hard to explain away the inconvenient possibility that this was not actually our direct relative. One extreme interpretation suggested that the preserved leg bones were curved by both rickets, and by a life on horseback. The pain of the unfortunate individual's affliction had caused him to chronically furrow his brow in agony, leading to the excessive development of bone above the eye sockets.The subsequent history of human evolutionary studies is full of similarly fanciful interpretations. With tact and humor, Tattersall concludes that we are not the perfected products of natural processes, but instead the result of substantial doses of random happenstance.

    The calls to ban it were more or less instant.Re:cyclists is the tale of what happened next, of how we have spent two centuries wheeling our way about town and country on bikes--or on two-wheeled things that vaguely resembled what we now call bikes. Michael Hutchinson picks his way through those 200 years, discovering how cycling became a kinky vaudeville act for Parisians, how it became an American business empire, and how it went on to find a unique home in the British Isles. He considers the penny-farthing riders exploring the abandoned and lonely coaching roads during the railway era, and the Victorian high-society cyclists of the 1890s bicycle craze--a time when no aristocratic house party was without bicycles and when the Prince of Wales used to give himself an illicit thrill on a weekday afternoon by watching the women's riding-school in the Royal Albert Hall.Re:cyclists looks at how cycling became the sport, the pastime and the social life of millions of ordinary people, how it grew and how it suffered through the 1960s and '70s, and how at the dawn of the twenty-first century it rose again, much changed but still ultimately just someone careering along on two wheels.

    From such twenty-first-century forces, we have seen declines in previous global health gains, with sharp increases in vaccine-preventable and neglected diseases on the Arabian Peninsula, in Venezuela, in parts of Africa, and even on the Gulf Coast of the United States. In Preventing the Next Pandemic, international vaccine scientist and tropical disease and coronavirus expert Peter J. Hotez, MD, PhD, argues that we can--and must--rely on vaccine diplomacy to address this new world order in disease and global health. Detailing his years in the lab developing new vaccines, Hotez also recounts his travels around the world to shape vaccine partnerships with people in countries both rich and poor in an attempt to head off major health problems. Building on the legacy of Dr. Albert Sabin, who developed the oral polio vaccine with Soviet scientists at the height of the Cold War, he explains how he is still working to refresh and redirect vaccine diplomacy toward neglected and newly emerging diseases.Hotez reveals how--during his Obama-era tenure as the US Science Envoy for the Middle East and North Africa, which coincided with both the rise in these geopolitical forces and climate change--he witnessed tropical infectious diseases and established vaccine partnerships that may still combat them up close. He explores why, since 2015, we've seen the decline of global cooperation and cohesion, to the detriment of those programs that are meant to benefit the most vulnerable people in the world. Unfortunately, Hotez asserts, these negative global events kick off a never-ending loop. Problems in a country may lead to disease outbreaks, but those outbreaks can lead to further problems--such as the impact of coronavirus on China's society and economy, which has been felt around the globe. Zeroing in on the sociopolitical and environmental factors that drive our most controversial and pressing global health concerns, Hotez proposes historically proven methods to soothe fraught international relations while preparing us for a safer, healthier future. He hammers home the importance of public engagement to communicate the urgency of embracing science during troubled times.Touching on a range of disease, from leishmaniasis, schistosomiasis, and Middle East Respiratory Syndrome (MERS) to COVID-19, Preventing the Next Pandemic has always been a timely goal, but it will be even more important in a COVID and post-COVID world.

    Join us on a journey through how we understand the Universe, from its most basic particles and forces, to planets, stars and galaxies, and back through cosmic history to the birth of the cosmos. Conflicting notions about our place in the Universe are defined, defended and critiqued from scientific, philosophical and religious viewpoints. The authors' engaging and witty style addresses what fine-tuning might mean for the future of physics and the search for the ultimate laws of nature. Tackling difficult questions and providing thought-provoking answers, this volumes challenges us to consider our place in the cosmos, regardless of our initial convictions.

    It's impossible to look up at the stars and NOT think about it: Are we alone in the universe? Books, movies and television shows proliferate that attempt to answer this question and explore it. In Out There Space.com senior writer Dr. Michael Wall treats that question as merely the beginning, touching off a wild ride of exploration into the final frontier. He considers, for instance, the myriad of questions that would arise once we do discover life beyond Earth (an eventuality which, top NASA officials told Wall, is only drawing closer). What would the first aliens we meet look like?Would they be little green men or mere microbes?Would they be found on a planet in our own solar system or orbiting a star far, far away?Would they intend to harm us, and if so, how might they do it?And might they already have visited?Out There is arranged in a simple question-and-answer format. The answers are delivered in Dr. Wall's informal but informative style, which mixes in a healthy dose of humor and pop culture to make big ideas easier to swallow. Dr. Wall covers questions far beyond alien life, venturing into astronomy, physics, and the practical realities of what long-term life might be like for we mere humans in outer space, such as the idea of lunar colonies, and even economic implications. Dr. Wall also shares the insights of some of the leading lights in space exploration today, and shows how the next space age might be brighter than ever.

    In Beast and Man Mary Midgley, one of our foremost intellectuals, stresses continuities. What makes people tick? Largely, she asserts, the same things as animals. She tells us humans are rather more like other animals than we previously allowed ourselves to believe, and reminds us just how primitive we are in comparison to the sophistication of many animals. A veritable classic for our age, Beast and Man has helped change the way we think about ourselves and the world in which we live.

    Perhaps ideas have us. After all, ideas do appear to have a life of their own. And it is they, not us, that benefit most when they are spread. Many biologists have already come to the opinion that our genes are selfish entities, tricking us into helping them to reproduce. Is it the same with our ideas?     Jonnie Hughes, a science writer and documentary filmmaker, investigates the evolution of ideas in order to find out. Adopting the role of a cultural Charles Darwin, Hughes heads off, with his brother in tow, across the Midwest to observe firsthand the natural history of ideas—the patterns of their variation, inheritance, and selection in the cultural landscape. In place of Darwin’s oceanic islands, Hughes visits the “mind islands” of Native American tribes. Instead of finches, Hughes searches for signs of natural selection among the tepees.     With a knack for finding the humor in the quirks of the American cultural landscape, Hughes takes us on a tour from the Mall of America in Minneapolis to what he calls the “maul” of America—Custer’s last stand—stopping at road-sides and discoursing on sandwiches, the shape of cowboy hats, the evolution of barn roofs, the wording of jokes, the wearing of moustaches, and, of course, the telling features from tepees of different tribes. Original, witty, and engaging, On the Origin of Tepees offers a fresh way of understanding both our ideas and ourselves.

    But most of us know very little about how the disease works, why we treat it the way we do, and the personalities whose dedication got us where we are today. For fifty years, Dr. Vincent T. DeVita Jr. has been one of those key players: he has held just about every major position in the field, and he developed the first successful chemotherapy treatment for Hodgkin’s lymphoma, a breakthrough the American Society of Clinical Oncologists has called the top research advance in half a century of chemotherapy. As one of oncology’s leading figures, DeVita knows what cancer looks like from the lab bench and the bedside. The Death of Cancer is his illuminating and deeply personal look at the science and the history of one of the world’s most formidable diseases. In DeVita’s hands, even the most complex medical concepts are comprehensible.Cowritten with DeVita’s daughter, the science writer Elizabeth DeVita-Raeburn, The Death of Cancer is also a personal tale about the false starts and major breakthroughs, the strong-willed oncologists who clashed with conservative administrators (and one another), and the courageous patients whose willingness to test cutting-edge research helped those oncologists find potential treatments. An emotionally compelling and informative read, The Death of Cancer is also a call to arms. DeVita believes that we’re well on our way to curing cancer but that there are things we need to change in order to get there. Mortality rates are declining, but America’s cancer patients are still being shortchanged—by timid doctors, by misguided national agendas, by compromised bureaucracies, and by a lack of access to information about the strengths and weaknesses of the nation’s cancer centers.With historical depth and authenticity, DeVita reveals the true story of the fight against cancer. The Death of Cancer is an ambitious, vital book about a life-and-death subject that touches us all.