The new edition is thoroughly updated, including most notably a new chapter on innate immunity, a capstone chapter on immune responses in time and space, and many new focus boxes drawing attention to exciting clinical, evolutionary, or experimental connections that help bring the material to life.See what's in the LaunchPad

    No one can stop him--but he walks away. A miracle? No...dysentery. Microbes saved the Roman Empire. Nearly a millennium later, the microbes of the Black Death ended the Middle Ages, making possible the Renaissance, western democracy, and the scientific revolution. Soon after, microbes ravaged the Americas, paving the way for their European conquest. Again and again, microbes have shaped our health, our genetics, our history, our culture, our politics, even our religion and ethics. This book reveals much that scientists and cultural historians have learned about the pervasive interconnections between infectious microbes and humans. It also considers what our ongoing fundamental relationship with infectious microbes might mean for the future of the human species. The "good side" of history's worst epidemics The surprising debt we owe to killer diseases Where diseases came from... ...and where they may be going Children of pestilence: disease and civilization From Egypt to Mexico, the Romans to Attila the Hun STDs, sexual behavior, and culture How microbes may shape cultural cycles of puritanism and promiscuity

    The book guides genealogists in understanding various tests and determining what DNA segments came from which ancestor. The book explains how DNA testing helps when written records stop and discusses how testing proves or disprove oral family history. Learn which tests help adoptees; understand why you resemble your relatives and how testing can connect you with cousins you never knew. Discover how to encourage potential cousins to test and learn guidelines for becoming a project administrator, genetic genealogy speaker or facilitator for your genealogical society’s DNA interest group. A Genetic Genealogy Handbook: The Basics and Beyond helps experienced and fledgling researchers become genetic genealogists able to use DNA testing to resolve genealogical roadblocks."

    The 10,000 Year Explosion: How Civilization Accelerated Human Evolution

    The coloring book helps you memorize the anatomy content you need to know in both veterinary medicine and veterinary technology and gives you a fun way to review the information you have studied. All illustrations in the book are suitable for coloring and are of the highest quality, created by expert medical illustrators.Organized by body region, the book is divided into sections devoted to the head and neck; neck, back, and vertebral column; thorax; abdomen; pelvis; forlimb; and hindlimb.Numbered lead lines clearly identify structures to be colored and correspond to a numbered list beneath the illustration so you can easily visualize the veterinary anatomy. Plus, you can create your own color code using the numbered boxes provided for each illustration.Comprehensive veterinary anatomy coverage helps you reinforce your understanding of canine, feline, equine, porcine, ruminants, and avian anatomy.High quality illustrations make it easy for you to color in each anatomic region and review anatomic details.Self-study format provides a fun and interactive way to prepare for exams throughout your veterinary courses.Part of Elsevier's complete veterinary anatomy learning system, integrating core anatomy knowledge, engaging review, hands-on practice, and clinical application to give you a solid foundation for success!

    At the time, Watson was only 24, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science's greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions & bitter rivalries. With humility unspoiled by false modesty, Watson relates his & Crick's desperate efforts to beat Linus Pauling to the Holy Grail of life sciences, the identification of the basic building block of life. Never has a scientist been so truthful in capturing in words the flavor of his work.

    The most fatal virus known to science, rabies — a disease that spreads avidly from animals to humans — kills nearly one hundred percent of its victims once the infection takes root in the brain. In this critically acclaimed exploration, journalist Bill Wasik and veterinarian Monica Murphy chart four thousand years of the history, science, and cultural mythology of rabies. From Greek myths to zombie flicks, from the laboratory heroics of Louis Pasteur to the contemporary search for a lifesaving treatment, Rabid is a fresh and often wildly entertaining look at one of humankind’s oldest and most fearsome foes.

    She shows how the stalling of early twentieth century efforts in this direction allowed Freudians and social scientists to insist, with some justification, that they had better ways of analyzing and fixing minds.But when the Freudians overreached, they drove psychiatry into a state of crisis that a new “biological revolution” was meant to alleviate. Harrington shows how little that biological revolution had to do with breakthroughs in science, and why the field has fallen into a state of crisis in our own time.Mind Fixers makes clear that psychiatry’s waxing and waning biological enthusiasms have been shaped not just by developments in the clinic and lab, but also by a surprising range of social factors, including immigration, warfare, grassroots activism, and assumptions about race and gender. Government programs designed to empty the state mental hospitals, acrid rivalries between different factions in the field, industry profit mongering, consumerism, and an uncritical media have all contributed to the story as well.In focusing particularly on the search for the biological roots of schizophrenia, depression, and bipolar disorder, Harrington underscores the high human stakes for the millions of people who have sought medical answers for their mental suffering. This is not just a story about doctors and scientists, but about countless ordinary people and their loved ones.A clear-eyed, evenhanded, and yet passionate tour de force, Mind Fixers recounts the past and present struggle to make mental illness a biological problem in order to lay the groundwork for creating a better future, both for those who suffer and for those whose job it is to care for them.

    Photos throughout.

    Humans have feared them for centuries, long considering them the assassins and pariahs of the natural world.Now, in Venomous, the biologist Christie Wilcox investigates and illuminates the animals of our nightmares, arguing that they hold the keys to a deeper understanding of evolution, adaptation, and immunity. She reveals just how venoms function and what they do to the human body. With Wilcox as our guide, we encounter a jellyfish with tentacles covered in stinging cells that can kill humans in minutes; a two-inch caterpillar with toxic bristles that trigger hemorrhaging; and a stunning blue-ringed octopus capable of inducing total paralysis. How do these animals go about their deadly work? How did they develop such intricate, potent toxins? Wilcox takes us around the world and down to the cellular level to find out.Throughout her journey, Wilcox meets the intrepid scientists who risk their lives studying these lethal beasts, as well as “self-immunizers” who deliberately expose themselves to snakebites. Along the way, she puts her own life on the line, narrowly avoiding being envenomated herself. Drawing on her own research, Wilcox explains how venom scientists are untangling the mechanisms of some of our most devastating diseases, and reports on pharmacologists who are already exploiting venoms to produce lifesaving drugs. We discover that venomous creatures are in fact keystone species that play crucial roles in their ecosystems and ours—and for this alone, they ought to be protected and appreciated.Thrilling and surprising at every turn, Venomous will change everything you thought you knew about the planet’s most dangerous animals.

    They were hunter-gatherers, consummate foraging experts, but taking the world as they found it. Then a revolution occurred – our ancestors’ interaction with other species changed. They began to tame them. The human population boomed; civilization began.In her new book, Tamed, Alice Roberts uncovers the amazing deep history of ten familiar species with incredible wild pasts: dogs, apples and wheat; cattle; potatoes and chickens; rice, maize, and horses – and, finally, humans. Alice Roberts not only reveals how becoming part of our world changed these animals and plants, but shows how they became our allies, essential to the survival and success of our own species – and to our future.Enlightening, wide-ranging and endlessly fascinating, Tamed is an epic story, encompassing hundreds of thousands of years of history and archaeology alongside cutting-edge genetics and anthropology. Yet it is also a deeply personal journey that will change how we see ourselves and the species on which we have left our mark.

    These great beasts, or “megafauna,” lived on every habitable continent and on many islands. With a handful of exceptions, all are now gone.What caused the disappearance of these prehistoric behemoths? No one event can be pinpointed as a specific cause, but several factors may have played a role. Paleomammalogist Ross D. E. MacPhee explores them all, examining the leading extinction theories, weighing the evidence, and presenting his own conclusions. He shows how theories of human overhunting and catastrophic climate change fail to account for critical features of these extinctions, and how new thinking is needed to elucidate these mysterious losses.Along the way, we learn how time is determined in earth history; how DNA is used to explain the genomics and phylogenetic history of megafauna—and how synthetic biology and genetic engineering may be able to reintroduce these giants of the past. Until then, gorgeous four-color illustrations by Peter Schouten re-create these megabeasts here in vivid detail.

    It strikes a balance between theory and application by incorporating real-world examples; helping students visualize the three-dimensional atomic and molecular structures that are the basis of chemical activity; and developing problem-solving and critical thinking skills. Although the fifth edition incorporates many new features, such as macro to micro artwork, six new animations correlated to the text, and the addition of new hand-sketched worked examples, General Chemistry is still 200 to 300 pages shorter and much less expensive than other two-semester textbooks. Dr. Chang's concise-but-thorough approach will appeal to efficiency-minded instructors and value-conscious students.

    Juan is that rarest of rarities, a scholar with a sense of humor. He fearlessly tours the brain's mysterious corridors, discussing such wide-ranging topics as phobias, compulsive water drinking, serial killers, the secrets of hypnotism, and the man who thought he was a cat. You will find this book absolutely engrossing.Do kleptomaniacs have a legitimate excuse to steal? Can excessive TV watching physically "shape" a child's growing brain?These answers and scores more fill Dr. Stephen Juan's fascinating and endlessly entertaining book The Odd Brain. Following up his popular first book, The Odd Body, Dr. Juan takes us on an animated tour of the enigmatic organ that sits on top of them all.Equal parts scholarly professor--he teaches at the University of Sydney--cultural detective, and theater of oddities tour guide, Dr. Juan explores bizarre brain disorders and the normal-but-still-weird brain phenomena that we all occasionally experience (like deja vu). Through it all, Dr. Juan pulls off the nifty trick of making the clinical both clear and entertaining.Each chapter is packed with real-life anecdotes and case studies. These include the Criminal Brain, the Savant Brain, the Shy Brain, the Suicidal Brain, the Thrill-Seeking Brain, the Obsessive-Compulsive Brain, and more than 20 others.For anyone who's ever witnessed unusual behavior and thought, "Now, what would make a person do that?" The Odd Brain is sure to have an answer.

    Yet The Origin of Species (1859) is also a humane and inspirational vision of ecological interrelatedness, revealing the complex mutual interdependencies between animal and plant life, climate and physical environment, and—by implication—within the human world. Written for the general reader, in a style which combines the rigour of science with the subtlety of literature, The Origin of Species remains one of the founding documents of the modern age.